FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7526, 251 aa 1>>>pF1KB7526 251 - 251 aa - 251 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2828+/-0.000346; mu= 0.8008+/- 0.022 mean_var=162.4367+/-33.525, 0's: 0 Z-trim(119.6): 7 B-trim: 440 in 1/56 Lambda= 0.100631 statistics sampled from 33830 (33839) to 33830 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.397), width: 16 Scan time: 7.280 The best scores are: opt bits E(85289) NP_057059 (OMIM: 300754) transcription initiation ( 251) 1658 252.1 7.1e-67 NP_001015892 (OMIM: 600822) transcription initiati ( 264) 1317 202.6 6e-52 NP_003178 (OMIM: 600822) transcription initiation ( 264) 1317 202.6 6e-52 >>NP_057059 (OMIM: 300754) transcription initiation fact (251 aa) initn: 1658 init1: 1658 opt: 1658 Z-score: 1321.6 bits: 252.1 E(85289): 7.1e-67 Smith-Waterman score: 1658; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251) 10 20 30 40 50 60 pF1KB7 MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 AKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 CLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 QRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKR 190 200 210 220 230 240 250 pF1KB7 KHEDDDDNDIM ::::::::::: NP_057 KHEDDDDNDIM 250 >>NP_001015892 (OMIM: 600822) transcription initiation f (264 aa) initn: 1492 init1: 831 opt: 1317 Z-score: 1053.7 bits: 202.6 E(85289): 6e-52 Smith-Waterman score: 1317; 80.8% identity (92.2% similar) in 255 aa overlap (1-249:1-255) 10 20 30 40 50 60 pF1KB7 MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH ::::: : ::. :.:: .:::::::::::::::::::::::::::::::::::::::::: NP_001 MESGKTASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRY ::: .:::::::::::::::::::::::::::::::::.:::::::::::.::::::::: NP_001 AKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRY 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 CLTAPNYRLKSLIKKGPNQ-GRL-VPRLSVGAVSSKPTTPTIATP--QTVSVPNKVATPM :::::::::::: ::. .. ::. :::::::.:.:.:.:::..:: ::.:: .::.::: NP_001 CLTAPNYRLKSLQKKASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPM 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 SVTSQRFTVQIPPSQSTPVKP-VPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEA :.:.::::::.: ::: :: .:::.::::::::::.:: :::::::::.::::::::. NP_001 SLTGQRFTVQMPTSQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANES 190 200 210 220 230 240 240 250 pF1KB7 -NPLKRKHEDDDDNDIM : ::::.:::::.: NP_001 SNALKRKREDDDDDDDDDDDYDNL 250 260 >>NP_003178 (OMIM: 600822) transcription initiation fact (264 aa) initn: 1492 init1: 831 opt: 1317 Z-score: 1053.7 bits: 202.6 E(85289): 6e-52 Smith-Waterman score: 1317; 80.8% identity (92.2% similar) in 255 aa overlap (1-249:1-255) 10 20 30 40 50 60 pF1KB7 MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH ::::: : ::. :.:: .:::::::::::::::::::::::::::::::::::::::::: NP_003 MESGKTASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRY ::: .:::::::::::::::::::::::::::::::::.:::::::::::.::::::::: NP_003 AKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRY 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 CLTAPNYRLKSLIKKGPNQ-GRL-VPRLSVGAVSSKPTTPTIATP--QTVSVPNKVATPM :::::::::::: ::. .. ::. :::::::.:.:.:.:::..:: ::.:: .::.::: NP_003 CLTAPNYRLKSLQKKASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPM 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 SVTSQRFTVQIPPSQSTPVKP-VPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEA :.:.::::::.: ::: :: .:::.::::::::::.:: :::::::::.::::::::. NP_003 SLTGQRFTVQMPTSQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANES 190 200 210 220 230 240 240 250 pF1KB7 -NPLKRKHEDDDDNDIM : ::::.:::::.: NP_003 SNALKRKREDDDDDDDDDDDYDNL 250 260 251 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:56:04 2016 done: Sat Nov 5 07:56:05 2016 Total Scan time: 7.280 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]