FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7527, 155 aa 1>>>pF1KB7527 155 - 155 aa - 155 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1422+/-0.000291; mu= 9.2156+/- 0.018 mean_var=96.3741+/-18.808, 0's: 0 Z-trim(119.5): 6 B-trim: 30 in 1/51 Lambda= 0.130645 statistics sampled from 33562 (33568) to 33562 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.394), width: 16 Scan time: 5.560 The best scores are: opt bits E(85289) NP_004764 (OMIM: 604500) zinc finger HIT domain-co ( 155) 1057 208.4 3.8e-54 NP_001268361 (OMIM: 604500) zinc finger HIT domain ( 148) 659 133.4 1.4e-31 NP_001268362 (OMIM: 604500) zinc finger HIT domain ( 80) 486 100.6 5.6e-22 NP_001268363 (OMIM: 604500) zinc finger HIT domain ( 99) 402 84.8 3.9e-17 >>NP_004764 (OMIM: 604500) zinc finger HIT domain-contai (155 aa) initn: 1057 init1: 1057 opt: 1057 Z-score: 1093.0 bits: 208.4 E(85289): 3.8e-54 Smith-Waterman score: 1057; 100.0% identity (100.0% similar) in 155 aa overlap (1-155:1-155) 10 20 30 40 50 60 pF1KB7 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TVKPVENKDDDDSIADFLNSDEEEDRVSLQNLKNLGESATLRSLLLNPHLRQLMVNLDQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TVKPVENKDDDDSIADFLNSDEEEDRVSLQNLKNLGESATLRSLLLNPHLRQLMVNLDQG 70 80 90 100 110 120 130 140 150 pF1KB7 EDKAKLMRAYMQEPLFVEFADCCLGIVEPSQNEES ::::::::::::::::::::::::::::::::::: NP_004 EDKAKLMRAYMQEPLFVEFADCCLGIVEPSQNEES 130 140 150 >>NP_001268361 (OMIM: 604500) zinc finger HIT domain-con (148 aa) initn: 659 init1: 659 opt: 659 Z-score: 687.9 bits: 133.4 E(85289): 1.4e-31 Smith-Waterman score: 659; 100.0% identity (100.0% similar) in 95 aa overlap (1-95:1-95) 10 20 30 40 50 60 pF1KB7 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TVKPVENKDDDDSIADFLNSDEEEDRVSLQNLKNLGESATLRSLLLNPHLRQLMVNLDQG ::::::::::::::::::::::::::::::::::: NP_001 TVKPVENKDDDDSIADFLNSDEEEDRVSLQNLKNLDGLSSCHPGWSAAAQSRLTATSPSQ 70 80 90 100 110 120 130 140 150 pF1KB7 EDKAKLMRAYMQEPLFVEFADCCLGIVEPSQNEES NP_001 IQAILMPQPPEQLGLQAPATTPNQFLYF 130 140 >>NP_001268362 (OMIM: 604500) zinc finger HIT domain-con (80 aa) initn: 486 init1: 486 opt: 486 Z-score: 515.5 bits: 100.6 E(85289): 5.6e-22 Smith-Waterman score: 486; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:1-68) 10 20 30 40 50 60 pF1KB7 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TVKPVENKDDDDSIADFLNSDEEEDRVSLQNLKNLGESATLRSLLLNPHLRQLMVNLDQG :::::::: NP_001 TVKPVENKVMRKKTEFLCRI 70 80 >>NP_001268363 (OMIM: 604500) zinc finger HIT domain-con (99 aa) initn: 402 init1: 402 opt: 402 Z-score: 428.6 bits: 84.8 E(85289): 3.9e-17 Smith-Waterman score: 570; 63.9% identity (63.9% similar) in 155 aa overlap (1-155:1-99) 10 20 30 40 50 60 pF1KB7 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK ::::::::::::::::::::::::::::::::::::::: NP_001 MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHK--------------------- 10 20 30 70 80 90 100 110 120 pF1KB7 TVKPVENKDDDDSIADFLNSDEEEDRVSLQNLKNLGESATLRSLLLNPHLRQLMVNLDQG ::::::::::::::::::::::::: NP_001 -----------------------------------GESATLRSLLLNPHLRQLMVNLDQG 40 50 60 130 140 150 pF1KB7 EDKAKLMRAYMQEPLFVEFADCCLGIVEPSQNEES ::::::::::::::::::::::::::::::::::: NP_001 EDKAKLMRAYMQEPLFVEFADCCLGIVEPSQNEES 70 80 90 155 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:27:43 2016 done: Fri Nov 4 08:27:43 2016 Total Scan time: 5.560 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]