FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7530, 255 aa
  1>>>pF1KB7530 255 - 255 aa - 255 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7752+/-0.000301; mu= 14.1056+/- 0.019
 mean_var=104.7032+/-22.164, 0's: 0 Z-trim(119.7): 68  B-trim: 1780 in 1/53
 Lambda= 0.125341
 statistics sampled from 33807 (33977) to 33807 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.398), width:  16
 Scan time:  7.170

The best scores are:                                      opt bits E(85289)
NP_005584 (OMIM: 159990) myogenic factor 5 [Homo s ( 255) 1745 325.4 6.3e-89
NP_002469 (OMIM: 159970) myoblast determination pr ( 320)  564 111.9 1.4e-24
NP_002460 (OMIM: 159991,614408) myogenic factor 6  ( 242)  499 100.0 4.1e-21
NP_002470 (OMIM: 159980) myogenin [Homo sapiens]   ( 224)  471 94.9 1.3e-19


>>NP_005584 (OMIM: 159990) myogenic factor 5 [Homo sapie  (255 aa)
 initn: 1745 init1: 1745 opt: 1745  Z-score: 1717.5  bits: 325.4 E(85289): 6.3e-89
Smith-Waterman score: 1745; 100.0% identity (100.0% similar) in 255 aa overlap (1-255:1-255)

               10        20        30        40        50        60
pF1KB7 MDVMDGCQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGAHKAELQGSDEDEHVRAPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDVMDGCQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGAHKAELQGSDEDEHVRAPTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 HHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 TFDSIYCPDVSNVYATDKNSLSSLDCLSNIVDRITSSEQPGLPLQDLASLSPVASTDSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TFDSIYCPDVSNVYATDKNSLSSLDCLSNIVDRITSSEQPGLPLQDLASLSPVASTDSQP
              190       200       210       220       230       240

              250     
pF1KB7 ATPGASSSRLIYHVL
       :::::::::::::::
NP_005 ATPGASSSRLIYHVL
              250     

>>NP_002469 (OMIM: 159970) myoblast determination protei  (320 aa)
 initn: 758 init1: 550 opt: 564  Z-score: 562.0  bits: 111.9 E(85289): 1.4e-24
Smith-Waterman score: 767; 48.7% identity (68.5% similar) in 279 aa overlap (5-247:17-294)

                             10        20        30        40      
pF1KB7             MDVMDG--CQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGAH-KAE
                       ::  :.:. .. :::  :. ::. .: ... ::.   ::  : :
NP_002 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE
               10        20        30        40        50        60

                     50        60        70        80        90    
pF1KB7 LQ-----------GSDEDEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERR
        .           :. ::::::::.::::::.::.:::::::::.:. ::::::::::::
NP_002 EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR
               70        80        90       100       110       120

          100       110       120       130       140              
pF1KB7 RLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQ-------VENYYS
       ::.:::.:::::::::..::::::::::::::::::::.:: :::.:       .  .:.
NP_002 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA
              130       140       150       160       170       180

           150             160       170        180       190      
pF1KB7 L----PGQSC------SEPTSPTSNCSDGMPECNSP-VWSRKSSTFDSIYCPDVSNVYAT
            ::..       :. .:: ::::::: . ..:   .:. . ... :  .. .    
NP_002 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP
              190       200       210       220       230       240

        200        210       220          230       240       250  
pF1KB7 DKNS-LSSLDCLSNIVDRITSSEQPGLP---LQDLASLSPVASTDSQPATPGASSSRLIY
        :.. .:::::::.::.:: :.:.:. :   : :. : ::    ..   . : ::     
NP_002 GKSAAVSSLDCLSSIVERI-STESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQ
              250        260       270       280       290         

                            
pF1KB7 HVL                  
                            
NP_002 SPDAAPQCPAGANPNPIYQVL
     300       310       320

>>NP_002460 (OMIM: 159991,614408) myogenic factor 6 [Hom  (242 aa)
 initn: 484 init1: 396 opt: 499  Z-score: 500.1  bits: 100.0 E(85289): 4.1e-21
Smith-Waterman score: 499; 50.5% identity (69.6% similar) in 184 aa overlap (48-223:53-234)

        20        30        40        50          60           70  
pF1KB7 GSCIPSPEGEFGDEFVPRVAAFGAHKAELQGSDE--DEHVRAPTG---HHQAGHCLMWAC
                                     :::   .::: :: :    :  :.::.:::
NP_002 QPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWAC
             30        40        50        60        70        80  

             80        90       100       110       120       130  
pF1KB7 KACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIE
       :.:::::.  :::::::.::::::::.:.:::.::: :..:::::::::::::.:: :::
NP_002 KTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIE
             90       100       110       120       130       140  

              140       150        160       170       180         
pF1KB7 SLQELLR--EQVENYYSLPGQSCS-EPTSPTSNCSDGMPECNSPVWSRKSSTFDSIYCPD
        ::.::.  .: :..  :  .  : .: . . . .: .  :.:  :   :.   ..    
NP_002 RLQDLLHRLDQQEKMQELGVDPFSYRPKQENLEGADFLRTCSSQ-WPSVSDHSRGLVITA
            150       160       170       180        190       200 

     190       200       210       220       230       240         
pF1KB7 VSNVYATDKNSLSSLDCLSNIVDRITSSEQPGLPLQDLASLSPVASTDSQPATPGASSSR
         .  . :... ::: :::.::: : :::.  ::                          
NP_002 KEGGASIDSSASSSLRCLSSIVDSI-SSEERKLPCVEEVVEK                  
             210       220        230       240                    

     250     
pF1KB7 LIYHVL

>>NP_002470 (OMIM: 159980) myogenin [Homo sapiens]        (224 aa)
 initn: 461 init1: 393 opt: 471  Z-score: 473.1  bits: 94.9 E(85289): 1.3e-19
Smith-Waterman score: 471; 42.9% identity (64.8% similar) in 219 aa overlap (9-215:4-209)

               10        20        30            40              50
pF1KB7 MDVMDGCQFSPSEYFYDGSCIPSPEGEFGDEFVP-RVAAF---GAHKAELQ------GSD
               .  : :::.      :.   :....: .. .:   : ...::       :  
NP_002      MELYETSPYFYQ-----EPRFYDGENYLPVHLQGFEPPGYERTELTLSPEAPGPL
                    10             20        30        40        50

               60        70        80        90       100       110
pF1KB7 EDEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCT
       ::. . .:  .:  :.:: ::::.:::::...:::.:::.::.:::::::.:::.::: :
NP_002 EDKGLGTP--EHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRST
                 60        70        80        90       100        

              120       130         140       150       160        
pF1KB7 TTNPNQRLPKVEILRNAIRYIESLQELLR--EQVENYYSLPGQSCSEPTSPTSNCSDGMP
         :::::::::::::.::.::: :: ::   .: :      : .  .:  : :.::.   
NP_002 LLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVP-SECSSHSA
      110       120       130       140       150        160       

      170       180       190       200       210       220        
pF1KB7 ECNSPVWSRKSSTFDSIYCPDVSNVYATDKNSLSSLDCLSNIVDRITSSEQPGLPLQDLA
        : :: :.   :...    :  ... ..: ..  .:  :..::: ::             
NP_002 SC-SPEWG---SALEFSANPG-DHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETM
        170          180        190       200       210       220  

      230       240       250     
pF1KB7 SLSPVASTDSQPATPGASSSRLIYHVL
                                  
NP_002 PN                         
                                  




255 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:02:06 2016 done: Sat Nov  5 04:02:07 2016
 Total Scan time:  7.170 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]