FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7532, 256 aa 1>>>pF1KB7532 256 - 256 aa - 256 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2289+/-0.000332; mu= -1.4558+/- 0.021 mean_var=268.6598+/-55.562, 0's: 0 Z-trim(123.5): 6 B-trim: 428 in 1/59 Lambda= 0.078248 statistics sampled from 43334 (43340) to 43334 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.508), width: 16 Scan time: 7.700 The best scores are: opt bits E(85289) NP_006226 (OMIM: 601206) POU domain class 2-associ ( 256) 1755 210.3 2.7e-54 XP_006718922 (OMIM: 601206) PREDICTED: POU domain ( 276) 1711 205.4 9e-53 XP_005271650 (OMIM: 601206) PREDICTED: POU domain ( 303) 1707 205.0 1.3e-52 XP_005271651 (OMIM: 601206) PREDICTED: POU domain ( 303) 1707 205.0 1.3e-52 XP_016873421 (OMIM: 601206) PREDICTED: POU domain ( 157) 1047 130.2 2.2e-30 XP_006718923 (OMIM: 601206) PREDICTED: POU domain ( 204) 999 124.9 1.1e-28 >>NP_006226 (OMIM: 601206) POU domain class 2-associatin (256 aa) initn: 1755 init1: 1755 opt: 1755 Z-score: 1095.7 bits: 210.3 E(85289): 2.7e-54 Smith-Waterman score: 1755; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256) 10 20 30 40 50 60 pF1KB7 MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPAVGPPLEGPEHQAPLTYFPWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPAVGPPLEGPEHQAPLTYFPWP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAASSLTIDKLLLEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAASSLTIDKLLLEEE 190 200 210 220 230 240 250 pF1KB7 DSDAYALNHTLSVEGF :::::::::::::::: NP_006 DSDAYALNHTLSVEGF 250 >>XP_006718922 (OMIM: 601206) PREDICTED: POU domain clas (276 aa) initn: 1705 init1: 1705 opt: 1711 Z-score: 1068.4 bits: 205.4 E(85289): 9e-53 Smith-Waterman score: 1711; 98.0% identity (99.2% similar) in 256 aa overlap (2-256:21-276) 10 20 30 40 pF1KB7 MLWQKP-TAPEQAPAPARPYQGVRVKEPVKELLRRKRGHAS .:.. :::::::::::::::::::::::::::::::::: XP_006 MEQRQPILSGTMAADPVVSAVWMRAATAPEQAPAPARPYQGVRVKEPVKELLRRKRGHAS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 SGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 PWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 VGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDM 190 200 210 220 230 240 230 240 250 pF1KB7 EDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF :::::::::::::::::::::::::::::::::::: XP_006 EDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF 250 260 270 >>XP_005271650 (OMIM: 601206) PREDICTED: POU domain clas (303 aa) initn: 1707 init1: 1707 opt: 1707 Z-score: 1065.4 bits: 205.0 E(85289): 1.3e-52 Smith-Waterman score: 1707; 99.2% identity (99.6% similar) in 252 aa overlap (5-256:52-303) 10 20 30 pF1KB7 MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRR . :::::::::::::::::::::::::::: XP_005 LQNSLAAGCGHVPGSQETRGSCGSPATSIGRATAPEQAPAPARPYQGVRVKEPVKELLRR 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 KRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPA 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 TLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTR 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB7 SSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPE 210 220 230 240 250 260 220 230 240 250 pF1KB7 PVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF :::::::::::::::::::::::::::::::::::::::::: XP_005 PVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF 270 280 290 300 >>XP_005271651 (OMIM: 601206) PREDICTED: POU domain clas (303 aa) initn: 1707 init1: 1707 opt: 1707 Z-score: 1065.4 bits: 205.0 E(85289): 1.3e-52 Smith-Waterman score: 1707; 99.2% identity (99.6% similar) in 252 aa overlap (5-256:52-303) 10 20 30 pF1KB7 MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRR . :::::::::::::::::::::::::::: XP_005 LQNSLAAGCGHVPGSQETRGSCGSPATSIGRATAPEQAPAPARPYQGVRVKEPVKELLRR 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 KRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPA 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 TLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTR 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB7 SSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPE 210 220 230 240 250 260 220 230 240 250 pF1KB7 PVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF :::::::::::::::::::::::::::::::::::::::::: XP_005 PVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF 270 280 290 300 >>XP_016873421 (OMIM: 601206) PREDICTED: POU domain clas (157 aa) initn: 1047 init1: 1047 opt: 1047 Z-score: 666.5 bits: 130.2 E(85289): 2.2e-30 Smith-Waterman score: 1047; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152) 10 20 30 40 50 60 pF1KB7 MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPAVGPPLEGPEHQAPLTYFPWP :::::::::::::::::::::::::::::::: XP_016 DMYVQPVCPSYTVVGPSSVLTYASPPLITNVTGPVSS 130 140 150 190 200 210 220 230 240 pF1KB7 QPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAASSLTIDKLLLEEE >>XP_006718923 (OMIM: 601206) PREDICTED: POU domain clas (204 aa) initn: 999 init1: 999 opt: 999 Z-score: 635.7 bits: 124.9 E(85289): 1.1e-28 Smith-Waterman score: 999; 98.6% identity (99.3% similar) in 148 aa overlap (5-152:52-199) 10 20 30 pF1KB7 MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRR . :::::::::::::::::::::::::::: XP_006 LQNSLAAGCGHVPGSQETRGSCGSPATSIGRATAPEQAPAPARPYQGVRVKEPVKELLRR 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 KRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPA 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 TLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTGP 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB7 SSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPE XP_006 VSS 256 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:29:28 2016 done: Fri Nov 4 08:29:30 2016 Total Scan time: 7.700 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]