FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7533, 171 aa 1>>>pF1KB7533 171 - 171 aa - 171 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2965+/-0.000269; mu= 13.2085+/- 0.017 mean_var=71.8379+/-14.707, 0's: 0 Z-trim(119.2): 55 B-trim: 1904 in 1/60 Lambda= 0.151320 statistics sampled from 32981 (33043) to 32981 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.387), width: 16 Scan time: 4.830 The best scores are: opt bits E(85289) XP_011521131 (OMIM: 609759) PREDICTED: probable hi ( 377) 1175 264.9 9.6e-71 XP_016878373 (OMIM: 609759) PREDICTED: probable hi ( 313) 811 185.4 6.9e-47 XP_016878372 (OMIM: 609759) PREDICTED: probable hi ( 419) 811 185.5 8.7e-47 XP_016878371 (OMIM: 609759) PREDICTED: probable hi ( 419) 811 185.5 8.7e-47 NP_001091643 (OMIM: 609759) probable histone-lysin ( 492) 811 185.6 9.9e-47 XP_005256331 (OMIM: 609759) PREDICTED: probable hi ( 492) 811 185.6 9.9e-47 NP_001297143 (OMIM: 609760) histone-lysine N-methy ( 894) 798 182.9 1.1e-45 NP_064612 (OMIM: 609760) histone-lysine N-methyltr ( 894) 798 182.9 1.1e-45 XP_011518532 (OMIM: 616347) PREDICTED: PR domain-c ( 516) 333 81.2 2.7e-15 NP_001243625 (OMIM: 616347) PR domain-containing p ( 477) 331 80.8 3.4e-15 XP_011518533 (OMIM: 616347) PREDICTED: PR domain-c ( 477) 331 80.8 3.4e-15 XP_011518530 (OMIM: 616347) PREDICTED: PR domain-c ( 968) 331 81.0 6e-15 XP_011518525 (OMIM: 616347) PREDICTED: PR domain-c (1177) 331 81.0 7e-15 XP_011518524 (OMIM: 616347) PREDICTED: PR domain-c (1177) 331 81.0 7e-15 XP_011518526 (OMIM: 616347) PREDICTED: PR domain-c (1177) 331 81.0 7e-15 NP_001243624 (OMIM: 616347) PR domain-containing p (1177) 331 81.0 7e-15 XP_011518527 (OMIM: 616347) PREDICTED: PR domain-c (1177) 331 81.0 7e-15 NP_036538 (OMIM: 605780) PR domain zinc finger pro ( 801) 160 43.6 0.00089 XP_005268650 (OMIM: 605780) PREDICTED: PR domain z ( 808) 149 41.2 0.0047 NP_001129082 (OMIM: 601196) PR domain zinc finger ( 226) 142 39.3 0.0049 XP_016857753 (OMIM: 601196) PREDICTED: PR domain z ( 310) 142 39.4 0.0063 XP_016866676 (OMIM: 603423) PREDICTED: PR domain z ( 789) 145 40.3 0.0085 XP_011534365 (OMIM: 603423) PREDICTED: PR domain z ( 789) 145 40.3 0.0085 XP_006715613 (OMIM: 603423) PREDICTED: PR domain z ( 796) 145 40.3 0.0086 NP_001189 (OMIM: 603423) PR domain zinc finger pro ( 825) 145 40.3 0.0088 XP_011534364 (OMIM: 603423) PREDICTED: PR domain z ( 839) 145 40.3 0.0089 >>XP_011521131 (OMIM: 609759) PREDICTED: probable histon (377 aa) initn: 1175 init1: 1175 opt: 1175 Z-score: 1391.1 bits: 264.9 E(85289): 9.6e-71 Smith-Waterman score: 1175; 100.0% identity (100.0% similar) in 171 aa overlap (1-171:207-377) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPN :::::::::::::::::::::::::::::: XP_011 EGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPN 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB7 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT 240 250 260 270 280 290 100 110 120 130 140 150 pF1KB7 KGRNCYEYVDGKDKSSANWMRTKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRTIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGRNCYEYVDGKDKSSANWMRTKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRTIC 300 310 320 330 340 350 160 170 pF1KB7 KKTSPTRESLPRGSESGAAIF ::::::::::::::::::::: XP_011 KKTSPTRESLPRGSESGAAIF 360 370 >>XP_016878373 (OMIM: 609759) PREDICTED: probable histon (313 aa) initn: 814 init1: 794 opt: 811 Z-score: 962.8 bits: 185.4 E(85289): 6.9e-47 Smith-Waterman score: 811; 84.8% identity (90.6% similar) in 138 aa overlap (1-136:28-165) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSA ::::::::::::::::::::::::::::::::: XP_016 MYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITKGR 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 NCYEYVDGKDKSSANWMR--TKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRTICK :::::::::::::::::: . ::: . ... .. .: :: XP_016 NCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVWSGD 130 140 150 160 170 180 160 170 pF1KB7 KTSPTRESLPRGSESGAAIF XP_016 EYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQRSIH 190 200 210 220 230 240 >>XP_016878372 (OMIM: 609759) PREDICTED: probable histon (419 aa) initn: 814 init1: 794 opt: 811 Z-score: 960.9 bits: 185.5 E(85289): 8.7e-47 Smith-Waterman score: 811; 84.8% identity (90.6% similar) in 138 aa overlap (1-136:134-271) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPN :::::::::::::::::::::::::::::: XP_016 EGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPN 110 120 130 140 150 160 40 50 60 70 80 90 pF1KB7 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT 170 180 190 200 210 220 100 110 120 130 140 pF1KB7 KGRNCYEYVDGKDKSSANWMR--TKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRT ::::::::::::::::::::: . ::: . ... .. .: :: XP_016 KGRNCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVW 230 240 250 260 270 280 150 160 170 pF1KB7 ICKKTSPTRESLPRGSESGAAIF XP_016 SGDEYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQR 290 300 310 320 330 340 >>XP_016878371 (OMIM: 609759) PREDICTED: probable histon (419 aa) initn: 814 init1: 794 opt: 811 Z-score: 960.9 bits: 185.5 E(85289): 8.7e-47 Smith-Waterman score: 811; 84.8% identity (90.6% similar) in 138 aa overlap (1-136:134-271) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPN :::::::::::::::::::::::::::::: XP_016 EGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPN 110 120 130 140 150 160 40 50 60 70 80 90 pF1KB7 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT 170 180 190 200 210 220 100 110 120 130 140 pF1KB7 KGRNCYEYVDGKDKSSANWMR--TKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRT ::::::::::::::::::::: . ::: . ... .. .: :: XP_016 KGRNCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVW 230 240 250 260 270 280 150 160 170 pF1KB7 ICKKTSPTRESLPRGSESGAAIF XP_016 SGDEYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQR 290 300 310 320 330 340 >>NP_001091643 (OMIM: 609759) probable histone-lysine N- (492 aa) initn: 814 init1: 794 opt: 811 Z-score: 959.9 bits: 185.6 E(85289): 9.9e-47 Smith-Waterman score: 811; 84.8% identity (90.6% similar) in 138 aa overlap (1-136:207-344) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPN :::::::::::::::::::::::::::::: NP_001 EGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPN 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB7 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT 240 250 260 270 280 290 100 110 120 130 140 pF1KB7 KGRNCYEYVDGKDKSSANWMR--TKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRT ::::::::::::::::::::: . ::: . ... .. .: :: NP_001 KGRNCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVW 300 310 320 330 340 350 150 160 170 pF1KB7 ICKKTSPTRESLPRGSESGAAIF NP_001 SGDEYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQR 360 370 380 390 400 410 >>XP_005256331 (OMIM: 609759) PREDICTED: probable histon (492 aa) initn: 814 init1: 794 opt: 811 Z-score: 959.9 bits: 185.6 E(85289): 9.9e-47 Smith-Waterman score: 811; 84.8% identity (90.6% similar) in 138 aa overlap (1-136:207-344) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPN :::::::::::::::::::::::::::::: XP_005 EGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPN 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB7 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT 240 250 260 270 280 290 100 110 120 130 140 pF1KB7 KGRNCYEYVDGKDKSSANWMR--TKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRT ::::::::::::::::::::: . ::: . ... .. .: :: XP_005 KGRNCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVW 300 310 320 330 340 350 150 160 170 pF1KB7 ICKKTSPTRESLPRGSESGAAIF XP_005 SGDEYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQR 360 370 380 390 400 410 >>NP_001297143 (OMIM: 609760) histone-lysine N-methyltra (894 aa) initn: 781 init1: 781 opt: 798 Z-score: 940.9 bits: 182.9 E(85289): 1.1e-45 Smith-Waterman score: 798; 83.3% identity (89.9% similar) in 138 aa overlap (1-136:207-344) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPN :::::::::::::::::::::::::::::: NP_001 ERKMYSLRERKGHAYKEVSEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPN 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB7 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: NP_001 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANNGYSWLIT 240 250 260 270 280 290 100 110 120 130 140 pF1KB7 KGRNCYEYVDGKDKSSANWMR--TKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRT ::::::::::::::: ::::: . ::: . ... .. .: :: NP_001 KGRNCYEYVDGKDKSWANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVW 300 310 320 330 340 350 150 160 170 pF1KB7 ICKKTSPTRESLPRGSESGAAIF NP_001 YGDEYGQELGIKWGSKWKKELMAGREPKPEIHPCPSCCLAFSSQKFLSQHVERNHSSQNF 360 370 380 390 400 410 >>NP_064612 (OMIM: 609760) histone-lysine N-methyltransf (894 aa) initn: 781 init1: 781 opt: 798 Z-score: 940.9 bits: 182.9 E(85289): 1.1e-45 Smith-Waterman score: 798; 83.3% identity (89.9% similar) in 138 aa overlap (1-136:207-344) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPN :::::::::::::::::::::::::::::: NP_064 ERKMYSLRERKGHAYKEVSEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPN 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB7 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLIT ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: NP_064 RSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANNGYSWLIT 240 250 260 270 280 290 100 110 120 130 140 pF1KB7 KGRNCYEYVDGKDKSSANWMR--TKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRT ::::::::::::::: ::::: . ::: . ... .. .: :: NP_064 KGRNCYEYVDGKDKSWANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVW 300 310 320 330 340 350 150 160 170 pF1KB7 ICKKTSPTRESLPRGSESGAAIF NP_064 YGDEYGQELGIKWGSKWKKELMAGREPKPEIHPCPSCCLAFSSQKFLSQHVERNHSSQNF 360 370 380 390 400 410 >>XP_011518532 (OMIM: 616347) PREDICTED: PR domain-conta (516 aa) initn: 344 init1: 177 opt: 333 Z-score: 395.7 bits: 81.2 E(85289): 2.7e-15 Smith-Waterman score: 333; 41.6% identity (72.6% similar) in 113 aa overlap (2-114:79-188) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPNR ::..:.: : ::::.::.:. : : :.: XP_011 MEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDR 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 SALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITK .::..: :... . .. . ::. .: : ::::::.:. ....:. .::::. XP_011 AALTIPQGMEVVKDTSGESDVRCVNEV--IPKGHIFGPYEGQISTQDKSAGF-FSWLIVD 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB7 GRNCYEYVDGKDKSSANWMRTKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRTICK : :. .::.:...:::::. : XP_011 KNNRYKSIDGSDETKANWMRNVAHLAERKRKPKFSKEELDILVTEVTHHEAVLFGRETMR 170 180 190 200 210 220 >>NP_001243625 (OMIM: 616347) PR domain-containing prote (477 aa) initn: 325 init1: 177 opt: 331 Z-score: 393.8 bits: 80.8 E(85289): 3.4e-15 Smith-Waterman score: 331; 41.8% identity (72.7% similar) in 110 aa overlap (2-111:79-185) 10 20 30 pF1KB7 MCQNFFIDSCAAHGPPTFVKDSAVDKGHPNR ::..:.: : ::::.::.:. : : :.: NP_001 MEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDR 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 SALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITK .::..: :... . .. . ::. .: : ::::::.:. ....:. .::::. NP_001 AALTIPQGMEVVKDTSGESDVRCVNEV--IPKGHIFGPYEGQISTQDKSAGF-FSWLIVD 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB7 GRNCYEYVDGKDKSSANWMRTKARDPSMSLMLSGLFKSKISQSTCGTQSLLSELPRTICK : :. .::.:...::::: NP_001 KNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWY 170 180 190 200 210 220 171 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:07:12 2016 done: Sat Nov 5 18:07:13 2016 Total Scan time: 4.830 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]