Result of FASTA (omim) for pF1KB7538
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7538, 258 aa
  1>>>pF1KB7538 258 - 258 aa - 258 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1817+/-0.000302; mu= 6.7779+/- 0.019
 mean_var=118.7945+/-23.919, 0's: 0 Z-trim(120.7): 8  B-trim: 0 in 0/57
 Lambda= 0.117673
 statistics sampled from 36268 (36276) to 36268 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.425), width:  16
 Scan time:  6.570

The best scores are:                                      opt bits E(85289)
NP_057351 (OMIM: 300583) transcription cofactor ve ( 258) 1788 313.7 2.1e-85
NP_872586 (OMIM: 609979) transcription cofactor ve ( 317)  230 49.3   1e-05
XP_005266940 (OMIM: 609979) PREDICTED: transcripti ( 318)  230 49.3   1e-05
NP_001307422 (OMIM: 609980) transcription cofactor ( 320)  218 47.2 4.3e-05
XP_006713201 (OMIM: 609980) PREDICTED: transcripti ( 325)  218 47.2 4.3e-05
NP_057290 (OMIM: 609980) transcription cofactor ve ( 326)  218 47.2 4.3e-05
NP_703154 (OMIM: 609979) transcription cofactor ve ( 143)  205 44.8  0.0001


>>NP_057351 (OMIM: 300583) transcription cofactor vestig  (258 aa)
 initn: 1788 init1: 1788 opt: 1788  Z-score: 1654.3  bits: 313.7 E(85289): 2.1e-85
Smith-Waterman score: 1788; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)

               10        20        30        40        50        60
pF1KB7 MEEMKKTAIRLPKGKQKPIKTEWNSRCVLFTYFQGDISSVVDEHFSRALSNIKSPQELTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MEEMKKTAIRLPKGKQKPIKTEWNSRCVLFTYFQGDISSVVDEHFSRALSNIKSPQELTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 SSQSEGVMLKNDDSMSPNQWRYSSPWTKPQPEVPVTNRAANCNLHVPGPMAVNQFSPSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SSQSEGVMLKNDDSMSPNQWRYSSPWTKPQPEVPVTNRAANCNLHVPGPMAVNQFSPSLA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RRASVRPGELWHFSSLAGTSSLEPGYSHPFPARHLVPEPQPDGKREPLLSLLQQDRCLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RRASVRPGELWHFSSLAGTSSLEPGYSHPFPARHLVPEPQPDGKREPLLSLLQQDRCLAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 PQESAARENGNPGQIAGSTGLLFNLPPGSVHYKKLYVSRGSASTSLPNETLSELETPGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PQESAARENGNPGQIAGSTGLLFNLPPGSVHYKKLYVSRGSASTSLPNETLSELETPGKY
              190       200       210       220       230       240

              250        
pF1KB7 SLTPPNHWGHPHRYLQHL
       ::::::::::::::::::
NP_057 SLTPPNHWGHPHRYLQHL
              250        

>>NP_872586 (OMIM: 609979) transcription cofactor vestig  (317 aa)
 initn: 217 init1: 184 opt: 230  Z-score: 223.5  bits: 49.3 E(85289): 1e-05
Smith-Waterman score: 251; 33.8% identity (51.8% similar) in 228 aa overlap (15-210:72-294)

                               10        20         30        40   
pF1KB7                 MEEMKKTAIRLPKGKQKPIKTEW-NSRCVLFTYFQGDISSVVDE
                                     :..: ..:. ::::::::::::::::::::
NP_872 NASPSSSGSGSSSFSSQTPASIKEEEGSPEKERPPEAEYINSRCVLFTYFQGDISSVVDE
              50        60        70        80        90       100 

            50        60        70           80           90       
pF1KB7 HFSRALSNIKSPQELTPSSQSEGVMLKND---DSMSPNQWRY--SSPWTKP-QPEVPVTN
       :::::::   .:.  .::  :  .  ..    :   : . :   .: :..  :  ::   
NP_872 HFSRALS---QPSSYSPSCTSSKAPRSSGPWRDCSFPMSQRSFPASFWNSAYQAPVPPPL
                110       120       130       140       150        

       100       110        120         130       140              
pF1KB7 RAANCNLHVPGPMAV-NQFSPSLARRASVRPG--ELWHFSSLAGTSSLEP--------GY
        .   . :   :.:. . .::. : .. .. :  : :: .    .   .:        . 
NP_872 GSPLATAHSELPFAAADPYSPA-ALHGHLHQGATEPWHHAHPHHAHPHHPYALGGALGAQ
      160       170       180        190       200       210       

        150          160       170       180       190             
pF1KB7 SHPFP---ARHLVPEPQPDGKREPLLSLLQQDRCLARPQESAARENGNP-------GQIA
       . :.:   : : :  :. : .  :::    . :  ::   . :   :.:       :. :
NP_872 AAPYPRPAAVHEVYAPHFDPRYGPLLMPAASGRP-ARLATAPAPAPGSPPCELSGKGEPA
       220       230       240       250        260       270      

            200       210       220       230       240       250  
pF1KB7 GST----GLLFNLPPGSVHYKKLYVSRGSASTSLPNETLSELETPGKYSLTPPNHWGHPH
       :..    :  :  : :.:                                          
NP_872 GAAWAGPGGPFASPSGDVAQGLGLSVDSARRYSLCGASLLS                   
        280       290       300       310                          

>>XP_005266940 (OMIM: 609979) PREDICTED: transcription c  (318 aa)
 initn: 217 init1: 184 opt: 230  Z-score: 223.5  bits: 49.3 E(85289): 1e-05
Smith-Waterman score: 251; 33.8% identity (51.8% similar) in 228 aa overlap (15-210:72-294)

                               10        20         30        40   
pF1KB7                 MEEMKKTAIRLPKGKQKPIKTEW-NSRCVLFTYFQGDISSVVDE
                                     :..: ..:. ::::::::::::::::::::
XP_005 NASPSSSGSGSSSFSSQTPASIKEEEGSPEKERPPEAEYINSRCVLFTYFQGDISSVVDE
              50        60        70        80        90       100 

            50        60        70           80           90       
pF1KB7 HFSRALSNIKSPQELTPSSQSEGVMLKND---DSMSPNQWRY--SSPWTKP-QPEVPVTN
       :::::::   .:.  .::  :  .  ..    :   : . :   .: :..  :  ::   
XP_005 HFSRALS---QPSSYSPSCTSSKAPRSSGPWRDCSFPMSQRSFPASFWNSAYQAPVPPPL
                110       120       130       140       150        

       100       110        120         130       140              
pF1KB7 RAANCNLHVPGPMAV-NQFSPSLARRASVRPG--ELWHFSSLAGTSSLEP--------GY
        .   . :   :.:. . .::. : .. .. :  : :: .    .   .:        . 
XP_005 GSPLATAHSELPFAAADPYSPA-ALHGHLHQGATEPWHHAHPHHAHPHHPYALGGALGAQ
      160       170       180        190       200       210       

        150          160       170       180       190             
pF1KB7 SHPFP---ARHLVPEPQPDGKREPLLSLLQQDRCLARPQESAARENGNP-------GQIA
       . :.:   : : :  :. : .  :::    . :  ::   . :   :.:       :. :
XP_005 AAPYPRPAAVHEVYAPHFDPRYGPLLMPAASGRP-ARLATAPAPAPGSPPCELSGKGEPA
       220       230       240       250        260       270      

            200       210       220       230       240       250  
pF1KB7 GST----GLLFNLPPGSVHYKKLYVSRGSASTSLPNETLSELETPGKYSLTPPNHWGHPH
       :..    :  :  : :.:                                          
XP_005 GAAWAGPGGPFASPSGDVAQGLGLSVDSGLQPQDKSKDVYWF                  
        280       290       300       310                          

>>NP_001307422 (OMIM: 609980) transcription cofactor ves  (320 aa)
 initn: 251 init1: 170 opt: 218  Z-score: 212.5  bits: 47.2 E(85289): 4.3e-05
Smith-Waterman score: 222; 36.2% identity (60.1% similar) in 163 aa overlap (15-157:75-232)

                               10        20         30        40   
pF1KB7                 MEEMKKTAIRLPKGKQKPIKTEW-NSRCVLFTYFQGDISSVVDE
                                     :..: . :. ::::::::::::::.:::::
NP_001 LAVFSKMQDSLEVTLPSKQEEEDEEEEEEEKDQPAEMEYLNSRCVLFTYFQGDIGSVVDE
           50        60        70        80        90       100    

            50        60         70        80              90      
pF1KB7 HFSRALSNIKSPQELTPSSQSE-GVMLKNDDSMSPNQWRYSSP---WT---KPQPEVPVT
       ::::::..  . .  .  :.:. :.     :: . .. : : :   ::   .: : .:  
NP_001 HFSRALGQAITLHPESAISKSKMGLTPLWRDSSALSSQRNSFPTSFWTSSYQPPP-APCL
          110       120       130       140       150        160   

        100          110           120          130       140      
pF1KB7 NRAANCNLHVPGP---MAVNQFSP----SLARRASVRP---GELWHFSSLAGTSSLEPGY
       . ... ...: ::   ... . ::    .: . . . :   .: : .     ::.. :.:
NP_001 G-GVHPDFQVTGPPGTFSAADPSPWPGHNLHQTGPAPPPAVSESWPYPL---TSQVSPSY
            170       180       190       200       210            

        150         160       170       180       190       200    
pF1KB7 SHPFPA--RHLVPEPQPDGKREPLLSLLQQDRCLARPQESAARENGNPGQIAGSTGLLFN
       ::   .  ::  :                                               
NP_001 SHMHDVYMRHHHPHAHMHHRHRHHHHHHHPPAGSALDPSYGPLLMPSVHAARIPAPQCDI
     220       230       240       250       260       270         

>>XP_006713201 (OMIM: 609980) PREDICTED: transcription c  (325 aa)
 initn: 251 init1: 170 opt: 218  Z-score: 212.3  bits: 47.2 E(85289): 4.3e-05
Smith-Waterman score: 222; 36.2% identity (60.1% similar) in 163 aa overlap (15-157:74-231)

                               10        20         30        40   
pF1KB7                 MEEMKKTAIRLPKGKQKPIKTEW-NSRCVLFTYFQGDISSVVDE
                                     :..: . :. ::::::::::::::.:::::
XP_006 LAVFSKMQDSLEVTLPSKQEEEDEEEEEEEKDQPAEMEYLNSRCVLFTYFQGDIGSVVDE
            50        60        70        80        90       100   

            50        60         70        80              90      
pF1KB7 HFSRALSNIKSPQELTPSSQSE-GVMLKNDDSMSPNQWRYSSP---WT---KPQPEVPVT
       ::::::..  . .  .  :.:. :.     :: . .. : : :   ::   .: : .:  
XP_006 HFSRALGQAITLHPESAISKSKMGLTPLWRDSSALSSQRNSFPTSFWTSSYQPPP-APCL
           110       120       130       140       150        160  

        100          110           120          130       140      
pF1KB7 NRAANCNLHVPGP---MAVNQFSP----SLARRASVRP---GELWHFSSLAGTSSLEPGY
       . ... ...: ::   ... . ::    .: . . . :   .: : .     ::.. :.:
XP_006 G-GVHPDFQVTGPPGTFSAADPSPWPGHNLHQTGPAPPPAVSESWPYPL---TSQVSPSY
             170       180       190       200       210           

        150         160       170       180       190       200    
pF1KB7 SHPFPA--RHLVPEPQPDGKREPLLSLLQQDRCLARPQESAARENGNPGQIAGSTGLLFN
       ::   .  ::  :                                               
XP_006 SHMHDVYMRHHHPHAHMHHRHRHHHHHHHPPAGSALDPSYGPLLMPSVHAARIPAPQCDI
      220       230       240       250       260       270        

>>NP_057290 (OMIM: 609980) transcription cofactor vestig  (326 aa)
 initn: 251 init1: 170 opt: 218  Z-score: 212.3  bits: 47.2 E(85289): 4.3e-05
Smith-Waterman score: 222; 36.2% identity (60.1% similar) in 163 aa overlap (15-157:75-232)

                               10        20         30        40   
pF1KB7                 MEEMKKTAIRLPKGKQKPIKTEW-NSRCVLFTYFQGDISSVVDE
                                     :..: . :. ::::::::::::::.:::::
NP_057 LAVFSKMQDSLEVTLPSKQEEEDEEEEEEEKDQPAEMEYLNSRCVLFTYFQGDIGSVVDE
           50        60        70        80        90       100    

            50        60         70        80              90      
pF1KB7 HFSRALSNIKSPQELTPSSQSE-GVMLKNDDSMSPNQWRYSSP---WT---KPQPEVPVT
       ::::::..  . .  .  :.:. :.     :: . .. : : :   ::   .: : .:  
NP_057 HFSRALGQAITLHPESAISKSKMGLTPLWRDSSALSSQRNSFPTSFWTSSYQPPP-APCL
          110       120       130       140       150        160   

        100          110           120          130       140      
pF1KB7 NRAANCNLHVPGP---MAVNQFSP----SLARRASVRP---GELWHFSSLAGTSSLEPGY
       . ... ...: ::   ... . ::    .: . . . :   .: : .     ::.. :.:
NP_057 G-GVHPDFQVTGPPGTFSAADPSPWPGHNLHQTGPAPPPAVSESWPYPL---TSQVSPSY
            170       180       190       200       210            

        150         160       170       180       190       200    
pF1KB7 SHPFPA--RHLVPEPQPDGKREPLLSLLQQDRCLARPQESAARENGNPGQIAGSTGLLFN
       ::   .  ::  :                                               
NP_057 SHMHDVYMRHHHPHAHMHHRHRHHHHHHHPPAGSALDPSYGPLLMPSVHAARIPAPQCDI
     220       230       240       250       260       270         

>>NP_703154 (OMIM: 609979) transcription cofactor vestig  (143 aa)
 initn: 205 init1: 184 opt: 205  Z-score: 205.8  bits: 44.8 E(85289): 0.0001
Smith-Waterman score: 210; 54.8% identity (68.5% similar) in 73 aa overlap (15-86:72-129)

                               10        20         30        40   
pF1KB7                 MEEMKKTAIRLPKGKQKPIKTEW-NSRCVLFTYFQGDISSVVDE
                                     :..: ..:. ::::::::::::::::::::
NP_703 NASPSSSGSGSSSFSSQTPASIKEEEGSPEKERPPEAEYINSRCVLFTYFQGDISSVVDE
              50        60        70        80        90       100 

            50        60        70        80        90       100   
pF1KB7 HFSRALSNIKSPQELTPSSQSEGVMLKNDDSMSPNQWRYSSPWTKPQPEVPVTNRAANCN
       :::::::.   :.  .::  :         : .:   : :.::                 
NP_703 HFSRALSQ---PSSYSPSCTS---------SKAP---RSSGPWRARRYSLCGASLLS   
                110                120          130       140      

           110       120       130       140       150       160   
pF1KB7 LHVPGPMAVNQFSPSLARRASVRPGELWHFSSLAGTSSLEPGYSHPFPARHLVPEPQPDG




258 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 08:32:12 2016 done: Fri Nov  4 08:32:13 2016
 Total Scan time:  6.570 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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