FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7541, 178 aa 1>>>pF1KB7541 178 - 178 aa - 178 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1750+/-0.000263; mu= 15.2903+/- 0.017 mean_var=75.4663+/-14.892, 0's: 0 Z-trim(120.9): 4 B-trim: 0 in 0/54 Lambda= 0.147638 statistics sampled from 36651 (36655) to 36651 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.43), width: 16 Scan time: 6.200 The best scores are: opt bits E(85289) NP_542382 (OMIM: 610237) mediator of RNA polymeras ( 178) 1191 261.7 4.4e-70 XP_011515662 (OMIM: 610237) PREDICTED: mediator of ( 157) 992 219.3 2.3e-57 NP_001269915 (OMIM: 610237) mediator of RNA polyme ( 143) 762 170.3 1.2e-42 >>NP_542382 (OMIM: 610237) mediator of RNA polymerase II (178 aa) initn: 1191 init1: 1191 opt: 1191 Z-score: 1379.1 bits: 261.7 E(85289): 4.4e-70 Smith-Waterman score: 1191; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178) 10 20 30 40 50 60 pF1KB7 MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 PNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 DGSKNDDRAGPPRFASEERREIAEVNKKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 DGSKNDDRAGPPRFASEERREIAEVNKKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN 130 140 150 160 170 >>XP_011515662 (OMIM: 610237) PREDICTED: mediator of RNA (157 aa) initn: 1006 init1: 992 opt: 992 Z-score: 1150.8 bits: 219.3 E(85289): 2.3e-57 Smith-Waterman score: 992; 99.3% identity (99.3% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KB7 MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 DGSKNDDRAGPPRFASEERREIAEVNKKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN ::::::::::::::::::::::::::: : XP_011 DGSKNDDRAGPPRFASEERREIAEVNKALSSVPEFLP 130 140 150 >>NP_001269915 (OMIM: 610237) mediator of RNA polymerase (143 aa) initn: 794 init1: 762 opt: 762 Z-score: 886.6 bits: 170.3 E(85289): 1.2e-42 Smith-Waterman score: 878; 80.3% identity (80.3% similar) in 178 aa overlap (1-178:1-143) 10 20 30 40 50 60 pF1KB7 MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEE :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVE-------- 70 80 90 100 110 130 140 150 160 170 pF1KB7 DGSKNDDRAGPPRFASEERREIAEVNKKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN ::::::::::::::::::::::::::::::: NP_001 ---------------------------KLKQKNQQLKQIMDQLRNLIWDINAMLAMRN 120 130 140 178 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:33:46 2016 done: Fri Nov 4 08:33:47 2016 Total Scan time: 6.200 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]