FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7543, 182 aa
1>>>pF1KB7543 182 - 182 aa - 182 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5816+/-0.000315; mu= 12.6690+/- 0.020
mean_var=83.7922+/-16.735, 0's: 0 Z-trim(116.7): 17 B-trim: 65 in 1/53
Lambda= 0.140111
statistics sampled from 27983 (28000) to 27983 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.328), width: 16
Scan time: 5.810
The best scores are: opt bits E(85289)
NP_001746 (OMIM: 121360) core-binding factor subun ( 182) 1240 259.7 1.9e-69
NP_074036 (OMIM: 121360) core-binding factor subun ( 187) 1150 241.5 5.9e-64
XP_016879302 (OMIM: 121360) PREDICTED: core-bindin ( 143) 647 139.7 1.9e-33
XP_005256269 (OMIM: 121360) PREDICTED: core-bindin ( 148) 647 139.7 2e-33
XP_016879301 (OMIM: 121360) PREDICTED: core-bindin ( 143) 593 128.8 3.7e-30
XP_006721384 (OMIM: 121360) PREDICTED: core-bindin ( 148) 503 110.6 1.1e-24
>>NP_001746 (OMIM: 121360) core-binding factor subunit b (182 aa)
initn: 1240 init1: 1240 opt: 1240 Z-score: 1367.7 bits: 259.7 E(85289): 1.9e-69
Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
130 140 150 160 170 180
pF1KB7 RP
::
NP_001 RP
>>NP_074036 (OMIM: 121360) core-binding factor subunit b (187 aa)
initn: 1175 init1: 1150 opt: 1150 Z-score: 1269.3 bits: 241.5 E(85289): 5.9e-64
Smith-Waterman score: 1150; 98.2% identity (99.4% similar) in 170 aa overlap (1-170:1-170)
10 20 30 40 50 60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_074 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_074 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
:::::::::::::::::::::::::::::::::::::::::::::.: .:
NP_074 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLGG
130 140 150 160 170 180
pF1KB7 RP
NP_074 GDDLKLR
>>XP_016879302 (OMIM: 121360) PREDICTED: core-binding fa (143 aa)
initn: 662 init1: 647 opt: 647 Z-score: 721.4 bits: 139.7 E(85289): 1.9e-33
Smith-Waterman score: 870; 78.6% identity (78.6% similar) in 182 aa overlap (1-182:1-143)
10 20 30 40 50 60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
::::::::::::::::::::::::::::::::::
XP_016 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGK--------------------------
70 80 90
130 140 150 160 170 180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------------QEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
100 110 120 130 140
pF1KB7 RP
::
XP_016 RP
>>XP_005256269 (OMIM: 121360) PREDICTED: core-binding fa (148 aa)
initn: 869 init1: 647 opt: 647 Z-score: 721.2 bits: 139.7 E(85289): 2e-33
Smith-Waterman score: 780; 75.3% identity (76.5% similar) in 170 aa overlap (1-170:1-131)
10 20 30 40 50 60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
::::::::::::::::::::::::::::::::::
XP_005 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGK--------------------------
70 80 90
130 140 150 160 170 180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
::::::::::::::::::::::::::::::::.: .:
XP_005 -------------QEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLGG
100 110 120 130 140
pF1KB7 RP
XP_005 GDDLKLR
>>XP_016879301 (OMIM: 121360) PREDICTED: core-binding fa (143 aa)
initn: 593 init1: 593 opt: 593 Z-score: 662.4 bits: 128.8 E(85289): 3.7e-30
Smith-Waterman score: 892; 78.6% identity (78.6% similar) in 182 aa overlap (1-182:1-143)
10 20 30 40 50 60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEI-----
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
::::::::::::::::::::::::::
XP_016 ----------------------------------VYLKAPMILNGVCVIWKGWIDLQRLD
60 70 80
130 140 150 160 170 180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
90 100 110 120 130 140
pF1KB7 RP
::
XP_016 RP
>>XP_006721384 (OMIM: 121360) PREDICTED: core-binding fa (148 aa)
initn: 896 init1: 503 opt: 503 Z-score: 563.9 bits: 110.6 E(85289): 1.1e-24
Smith-Waterman score: 802; 75.3% identity (76.5% similar) in 170 aa overlap (1-170:1-131)
10 20 30 40 50 60
pF1KB7 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEI-----
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
::::::::::::::::::::::::::
XP_006 ----------------------------------VYLKAPMILNGVCVIWKGWIDLQRLD
60 70 80
130 140 150 160 170 180
pF1KB7 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
:::::::::::::::::::::::::::::::::::::::::::::.: .:
XP_006 GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLGG
90 100 110 120 130 140
pF1KB7 RP
XP_006 GDDLKLR
182 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:35:31 2016 done: Fri Nov 4 08:35:32 2016
Total Scan time: 5.810 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]