FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7546, 264 aa 1>>>pF1KB7546 264 - 264 aa - 264 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4348+/-0.000767; mu= 2.8085+/- 0.046 mean_var=220.3210+/-46.911, 0's: 0 Z-trim(117.0): 860 B-trim: 438 in 1/55 Lambda= 0.086406 statistics sampled from 16702 (17686) to 16702 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.837), E-opt: 0.2 (0.543), width: 16 Scan time: 2.930 The best scores are: opt bits E(32554) CCDS13423.1 SNAI1 gene_id:6615|Hs108|chr20 ( 264) 1843 241.3 5.1e-64 CCDS6146.1 SNAI2 gene_id:6591|Hs108|chr8 ( 268) 903 124.2 9.7e-29 CCDS32505.1 SNAI3 gene_id:333929|Hs108|chr16 ( 292) 687 97.3 1.3e-20 CCDS13006.1 SCRT2 gene_id:85508|Hs108|chr20 ( 307) 519 76.3 2.7e-14 CCDS6421.1 SCRT1 gene_id:83482|Hs108|chr8 ( 348) 512 75.5 5.5e-14 >>CCDS13423.1 SNAI1 gene_id:6615|Hs108|chr20 (264 aa) initn: 1843 init1: 1843 opt: 1843 Z-score: 1262.8 bits: 241.3 E(32554): 5.1e-64 Smith-Waterman score: 1843; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264) 10 20 30 40 50 60 pF1KB7 MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPYDQAHLLAAIPPPEILNPTASLPMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPYDQAHLLAAIPPPEILNPTASLPMLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 WDSVLAPQAQPIAWASLRLQESPRVAELTSLSDEDSGKGSQPPSPPSPAPSSFSSTSVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 WDSVLAPQAQPIAWASLRLQESPRVAELTSLSDEDSGKGSQPPSPPSPAPSSFSSTSVSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRSHTLPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRSHTLPC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQA 190 200 210 220 230 240 250 260 pF1KB7 CARTFSRMSLLHKHQESGCSGCPR :::::::::::::::::::::::: CCDS13 CARTFSRMSLLHKHQESGCSGCPR 250 260 >>CCDS6146.1 SNAI2 gene_id:6591|Hs108|chr8 (268 aa) initn: 921 init1: 745 opt: 903 Z-score: 629.5 bits: 124.2 E(32554): 9.7e-29 Smith-Waterman score: 903; 54.4% identity (71.5% similar) in 274 aa overlap (1-259:1-264) 10 20 30 40 50 pF1KB7 MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPY-DQAHLLAAIPPPEILNPTASLPML :::::::.: . ..::::::: :.. .. .:: ... . .:: ::::. : :. CCDS61 MPRSFLVKKHFNASKKPNYSEL-DTHT--VIISPYLYESYSMPVIPQPEILSSGAYSPIT 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 IWDSVLAPQAQ-PIAWASLRLQESP--RVAELTSLSDEDSGKGSQPPSPPSPAPSSFSS- .: .. .:: : . . : : ::. :: .: : :: : ..: CCDS61 VWTTAAPFHAQLPNGLSPLSGYSSSLGRVSP-PPPSDTSSKDHSGSESPISDEEERLQSK 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 -TSVSSLEAE---------AYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLS .. ..::: .:..: ::.. ::: : :.::.:.::::.:::.: CCDS61 LSDPHAIEAEKFQCNLCNKTYSTFSGLAK-HKQLH-----CDAQSRKSFSCKYCDKEYVS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 LGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRA :::::::::.::::::: ::::::::::::::.::::::::::::::.::::::::::: CCDS61 LGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRA 180 190 200 210 220 230 230 240 250 260 pF1KB7 HLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR :::::::::::::. :..:::::::::::.:::: CCDS61 HLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCVAH 240 250 260 >>CCDS32505.1 SNAI3 gene_id:333929|Hs108|chr16 (292 aa) initn: 746 init1: 678 opt: 687 Z-score: 483.4 bits: 97.3 E(32554): 1.3e-20 Smith-Waterman score: 713; 46.1% identity (67.7% similar) in 297 aa overlap (1-263:1-290) 10 20 30 40 50 pF1KB7 MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPYDQAHLLAAIPPPEILNPTA--SLPM :::::::. :. .: ::: .:. .. :.. . :.. . : . :.. .::. CCDS32 MPRSFLVKTHSS-HRVPNYRRLE-TQREIN-GACSACGGLVVPLLPRDKEAPSVPGDLPQ 10 20 30 40 50 60 70 80 90 100 pF1KB7 LIWD--SVLA-------PQAQPIAWAS----LRLQE-SPRVAELTSLSDEDS-GKGSQPP :: :..: :. . :: :...: .::... . . .:: .. . :: CCDS32 -PWDRSSAVACISLPLLPRIEEALGASGLDALEVSEVDPRASRAAIVPLKDSLNHLNLPP 60 70 80 90 100 110 110 120 130 140 pF1KB7 S---P----PSPAPSSFSSTSVSSLEAEAYAAFPGLGQV-----PKQ-LAQLSEAKDL-- : :. .:. .. . : :: . :: . : . :: :.. ..: CCDS32 LLVLPTRWSPTLGPDRHGAPE-KLLGAERMPRAPGGFECFHCHKPYHTLAGLARHRQLHC 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB7 --QARKAFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGEK :. ..:.::::.::: ::::::::::.:::::.: :::::::::::::::::::::: CCDS32 HLQVGRVFTCKYCDKEYTSLGALKMHIRTHTLPCTCKICGKAFSRPWLLQGHVRTHTGEK 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 PFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR :..: :::::::::::::::::::::.:::.:. :..:::::::: .:.:::: :: CCDS32 PYACSHCSRAFADRSNLRAHLQTHSDAKKYRCRRCTKTFSRMSLLARHEESGC--CPGP 240 250 260 270 280 290 >>CCDS13006.1 SCRT2 gene_id:85508|Hs108|chr20 (307 aa) initn: 669 init1: 467 opt: 519 Z-score: 370.0 bits: 76.3 E(32554): 2.7e-14 Smith-Waterman score: 519; 58.3% identity (82.6% similar) in 115 aa overlap (146-260:178-292) 120 130 140 150 160 170 pF1KB7 TSVSSLEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRS ..:... : .: :.: :.:. :: ::. . CCDS13 QAGGGHRHACAECGKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHLLT 150 160 170 180 190 200 180 190 200 210 220 230 pF1KB7 HTLPCVCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKK :.: ::.::::::::::::::.:.:::::::.: ::..:::::::::::.:::: :. CCDS13 HNLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKH 210 220 230 240 250 260 240 250 260 pF1KB7 YQCQACARTFSRMSLLHKHQESGCSGCPR :.:. : ..:. : :::: :..:. CCDS13 YRCRQCDKSFALKSYLHKHCEAACAKAAEPPPPTPAGPAS 270 280 290 300 >>CCDS6421.1 SCRT1 gene_id:83482|Hs108|chr8 (348 aa) initn: 704 init1: 456 opt: 512 Z-score: 364.5 bits: 75.5 E(32554): 5.5e-14 Smith-Waterman score: 512; 57.9% identity (80.7% similar) in 114 aa overlap (146-259:214-327) 120 130 140 150 160 170 pF1KB7 TSVSSLEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRS ..:... : : :.: :.:. :. ::. . CCDS64 AAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLT 190 200 210 220 230 240 180 190 200 210 220 230 pF1KB7 HTLPCVCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKK : : ::.::::::::::::::.:.:::::::.: ::..:::::::::::.:::: :. CCDS64 HDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKH 250 260 270 280 290 300 240 250 260 pF1KB7 YQCQACARTFSRMSLLHKHQESGCSGCPR .::. : ..:. : :.:: ::.: CCDS64 FQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAPAPPQLSPVQA 310 320 330 340 264 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:37:20 2016 done: Fri Nov 4 08:37:20 2016 Total Scan time: 2.930 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]