Result of FASTA (omim) for
pF1KB7547
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7547, 185 aa
1>>>pF1KB7547 185 - 185 aa - 185 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4214+/-0.000306; mu= 13.9354+/- 0.019
mean_var=113.4150+/-23.323, 0's: 0 Z-trim(118.9): 306 B-trim: 84 in 1/54
Lambda= 0.120431
statistics sampled from 31847 (32270) to 31847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.378), width: 16
Scan time: 5.380
The best scores are: opt bits E(85289)
XP_016862910 (OMIM: 182230,601802) PREDICTED: home ( 185) 1273 231.1 7.7e-61
XP_011532507 (OMIM: 182230,601802) PREDICTED: home ( 185) 1273 231.1 7.7e-61
XP_006713442 (OMIM: 182230,601802) PREDICTED: home ( 185) 1273 231.1 7.7e-61
XP_011532506 (OMIM: 182230,601802) PREDICTED: home ( 185) 1273 231.1 7.7e-61
XP_005265583 (OMIM: 182230,601802) PREDICTED: home ( 185) 1273 231.1 7.7e-61
NP_003856 (OMIM: 182230,601802) homeobox expressed ( 185) 1273 231.1 7.7e-61
NP_776248 (OMIM: 138890,602471) homeobox protein g ( 257) 280 58.8 8.2e-09
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 248 53.4 5.2e-07
XP_006711451 (OMIM: 167420,202650) PREDICTED: pair ( 198) 238 51.3 1.1e-06
NP_008833 (OMIM: 167420,202650) paired mesoderm ho ( 217) 238 51.4 1.2e-06
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 238 51.4 1.2e-06
NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245) 238 51.5 1.3e-06
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 235 50.9 1.7e-06
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 237 51.5 2e-06
NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 235 51.1 2.2e-06
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 235 51.2 2.5e-06
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 235 51.2 2.6e-06
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 235 51.2 2.6e-06
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 235 51.2 2.6e-06
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 235 51.2 2.6e-06
NP_001595 (OMIM: 106210,120430,136520,148190,16555 ( 436) 235 51.2 2.6e-06
NP_001245391 (OMIM: 106210,120430,136520,148190,16 ( 436) 235 51.2 2.6e-06
NP_001245392 (OMIM: 106210,120430,136520,148190,16 ( 436) 235 51.2 2.6e-06
NP_001297087 (OMIM: 106210,120430,136520,148190,16 ( 436) 235 51.2 2.6e-06
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 231 50.4 3.4e-06
NP_001297089 (OMIM: 106210,120430,136520,148190,16 ( 286) 230 50.1 3.6e-06
NP_001297090 (OMIM: 106210,120430,136520,148190,16 ( 286) 230 50.1 3.6e-06
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 229 50.0 4.1e-06
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 225 49.1 5.1e-06
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 226 49.4 5.6e-06
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 225 49.2 6.1e-06
NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324) 223 49.0 9.2e-06
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 223 49.1 1e-05
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 223 49.1 1e-05
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 223 49.1 1e-05
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 221 48.6 1.2e-05
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 221 48.6 1.2e-05
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 221 48.6 1.2e-05
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 220 48.4 1.2e-05
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289) 220 48.4 1.2e-05
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 220 48.4 1.2e-05
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297) 220 48.4 1.2e-05
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297) 220 48.4 1.2e-05
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 220 48.5 1.5e-05
XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280) 217 47.9 1.7e-05
NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301) 217 47.9 1.8e-05
NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271) 216 47.7 1.9e-05
XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271) 216 47.7 1.9e-05
NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271) 216 47.7 1.9e-05
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 217 48.0 2e-05
>>XP_016862910 (OMIM: 182230,601802) PREDICTED: homeobox (185 aa)
initn: 1273 init1: 1273 opt: 1273 Z-score: 1213.3 bits: 231.1 E(85289): 7.7e-61
Smith-Waterman score: 1273; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
130 140 150 160 170 180
pF1KB7 TNLLE
:::::
XP_016 TNLLE
>>XP_011532507 (OMIM: 182230,601802) PREDICTED: homeobox (185 aa)
initn: 1273 init1: 1273 opt: 1273 Z-score: 1213.3 bits: 231.1 E(85289): 7.7e-61
Smith-Waterman score: 1273; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
130 140 150 160 170 180
pF1KB7 TNLLE
:::::
XP_011 TNLLE
>>XP_006713442 (OMIM: 182230,601802) PREDICTED: homeobox (185 aa)
initn: 1273 init1: 1273 opt: 1273 Z-score: 1213.3 bits: 231.1 E(85289): 7.7e-61
Smith-Waterman score: 1273; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
130 140 150 160 170 180
pF1KB7 TNLLE
:::::
XP_006 TNLLE
>>XP_011532506 (OMIM: 182230,601802) PREDICTED: homeobox (185 aa)
initn: 1273 init1: 1273 opt: 1273 Z-score: 1213.3 bits: 231.1 E(85289): 7.7e-61
Smith-Waterman score: 1273; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
130 140 150 160 170 180
pF1KB7 TNLLE
:::::
XP_011 TNLLE
>>XP_005265583 (OMIM: 182230,601802) PREDICTED: homeobox (185 aa)
initn: 1273 init1: 1273 opt: 1273 Z-score: 1213.3 bits: 231.1 E(85289): 7.7e-61
Smith-Waterman score: 1273; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
130 140 150 160 170 180
pF1KB7 TNLLE
:::::
XP_005 TNLLE
>>NP_003856 (OMIM: 182230,601802) homeobox expressed in (185 aa)
initn: 1273 init1: 1273 opt: 1273 Z-score: 1213.3 bits: 231.1 E(85289): 7.7e-61
Smith-Waterman score: 1273; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFN
130 140 150 160 170 180
pF1KB7 TNLLE
:::::
NP_003 TNLLE
>>NP_776248 (OMIM: 138890,602471) homeobox protein goose (257 aa)
initn: 289 init1: 269 opt: 280 Z-score: 279.2 bits: 58.8 E(85289): 8.2e-09
Smith-Waterman score: 280; 43.0% identity (71.1% similar) in 114 aa overlap (59-170:111-222)
30 40 50 60 70 80
pF1KB7 LDQKKDCVPLMKPHRPWADTCSSSGKDGNLCLHVPNPPSGISFP-SVVDHPMPEERASKY
: ::.:: : : ::. :.:.. :
NP_776 NNYFYGQLHVQAAPVGPACCGAVPPLGAQQCSCVPTPP-GYEGPGSVLVSPVPHQMLP-Y
90 100 110 120 130
90 100 110 120 130 140
pF1KB7 ENYFSASE-RLSLKRELSWYRGRRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLN
: . :. .:.: .: : :: :: ::..:.:.:::.:. . :: . ::.::.:..
NP_776 MNVGTLSRTELQLLNQLHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVH
140 150 160 170 180 190
150 160 170 180
pF1KB7 LEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFNTNLLE
:.:.....::.::::: .:..: :
NP_776 LREEKVEVWFKNRRAKWRRQKRSSSEESENAEKWNKTSSSKASPEKREEEGKSDLDSDS
200 210 220 230 240 250
>>NP_703149 (OMIM: 300154) homeobox protein ESX1 [Homo s (406 aa)
initn: 243 init1: 243 opt: 248 Z-score: 246.8 bits: 53.4 E(85289): 5.2e-07
Smith-Waterman score: 249; 35.4% identity (54.9% similar) in 144 aa overlap (30-168:83-199)
10 20 30 40 50
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHR-----PWADTCSSSGK
.:... :: ::.. : . . . .
NP_703 YGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEE
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB7 DGNLCLHVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTA
. .. :.: : :.... :.: :: :: :::
NP_703 PPQTTVEGPQPAEG---PQTAEGPQPPERK------------------------RRRRTA
120 130 140
120 130 140 150 160 170
pF1KB7 FTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLM
::: :.. ::: : . :: . :: :: .::: :::.:.:::::::: ::..:
NP_703 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN
150 160 170 180 190 200
180
pF1KB7 AKKNFNTNLLE
NP_703 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRP
210 220 230 240 250 260
>>XP_006711451 (OMIM: 167420,202650) PREDICTED: paired m (198 aa)
initn: 247 init1: 230 opt: 238 Z-score: 241.1 bits: 51.3 E(85289): 1.1e-06
Smith-Waterman score: 238; 48.6% identity (80.6% similar) in 72 aa overlap (107-178:46-114)
80 90 100 110 120 130
pF1KB7 HPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQIEVLENVFRVNCYPGID
. :: ::.:...:...:: ::. . ::
XP_006 SLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAF
20 30 40 50 60 70
140 150 160 170 180
pF1KB7 IREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFNTNLLE
.:::::...:: : :.:.::::::::..:..: ..:.::
XP_006 VREDLARRVNLTEARVQVWFQNRRAKFRRNERA---MLANKNASLLKSYSGDVTAVEQPI
80 90 100 110 120 130
XP_006 VPRPAPRPTDYLSWGTASPYSAMATYSATCANNSPAQGINMANSIANLRLKAKEYSLQRN
140 150 160 170 180 190
>>NP_008833 (OMIM: 167420,202650) paired mesoderm homeob (217 aa)
initn: 230 init1: 230 opt: 238 Z-score: 240.6 bits: 51.4 E(85289): 1.2e-06
Smith-Waterman score: 240; 32.7% identity (58.5% similar) in 159 aa overlap (20-178:33-161)
10 20 30 40
pF1KB7 MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTC
.::. ..: :.. : : . ::
NP_008 SSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQ------ADE-
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 SSSGKDGNLCLHVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGR
. :. : :. :. :: . :. . . :. .: .. :
NP_008 -NVGEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQ-------------------R
60 70 80 90
110 120 130 140 150 160
pF1KB7 RPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRE
: ::.:...:...:: ::. . :: .:::::...:: : :.:.::::::::..:..:
NP_008 RNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA
100 110 120 130 140 150
170 180
pF1KB7 SQFLMAKKNFNTNLLE
..:.::
NP_008 ---MLANKNASLLKSYSGDVTAVEQPIVPRPAPRPTDYLSWGTASPYRSSSLPRCCLHEG
160 170 180 190 200 210
185 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:07:38 2016 done: Sat Nov 5 18:07:39 2016
Total Scan time: 5.380 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]