FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7554, 270 aa 1>>>pF1KB7554 270 - 270 aa - 270 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0692+/-0.00032; mu= 5.7305+/- 0.020 mean_var=253.4285+/-51.818, 0's: 0 Z-trim(124.1): 174 B-trim: 2320 in 1/57 Lambda= 0.080565 statistics sampled from 44944 (45176) to 44944 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.53), width: 16 Scan time: 8.760 The best scores are: opt bits E(85289) NP_002720 (OMIM: 604420) hematopoietically-express ( 270) 1870 229.3 5.7e-60 NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 322 49.4 8.6e-06 NP_068777 (OMIM: 142995) H2.0-like homeobox protei ( 488) 326 50.2 8.8e-06 NP_004088 (OMIM: 600034) homeobox protein EMX1 [Ho ( 290) 296 46.4 7.1e-05 NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 285 45.2 0.00017 NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 ( 367) 276 44.2 0.00041 NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 259 42.0 0.0012 XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 258 42.1 0.0017 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 257 41.9 0.0017 NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 251 40.9 0.0018 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 254 41.5 0.002 NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 255 41.8 0.0022 XP_016868632 (OMIM: 610772) PREDICTED: homeobox pr ( 265) 249 40.9 0.0029 NP_004089 (OMIM: 269160,600035) homeobox protein E ( 252) 248 40.8 0.0031 XP_016867454 (OMIM: 603354) PREDICTED: homeobox pr ( 203) 246 40.4 0.0031 XP_016867453 (OMIM: 603354) PREDICTED: homeobox pr ( 204) 246 40.4 0.0032 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 246 40.5 0.0036 NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 245 40.5 0.0041 XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 245 40.5 0.0041 XP_011530999 (OMIM: 600034) PREDICTED: homeobox pr ( 119) 238 39.2 0.0042 NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 246 40.7 0.0043 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 244 40.3 0.0044 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 244 40.3 0.0044 NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 243 40.2 0.0048 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 244 40.4 0.0049 NP_796374 (OMIM: 605955) homeobox protein Nkx-6.2 ( 277) 243 40.2 0.0049 NP_067545 (OMIM: 603260) homeobox protein BarH-lik ( 254) 242 40.1 0.005 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 243 40.3 0.0054 XP_011538047 (OMIM: 186770) PREDICTED: T-cell leuk ( 269) 241 40.0 0.0056 XP_016872278 (OMIM: 605955) PREDICTED: homeobox pr ( 277) 241 40.0 0.0058 NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 240 40.0 0.0072 XP_011541345 (OMIM: 604823) PREDICTED: homeobox pr ( 233) 235 39.2 0.0083 NP_003649 (OMIM: 604823) homeobox protein BarH-lik ( 279) 235 39.3 0.0094 NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 236 39.5 0.0095 >>NP_002720 (OMIM: 604420) hematopoietically-expressed h (270 aa) initn: 1870 init1: 1870 opt: 1870 Z-score: 1197.6 bits: 229.3 E(85289): 5.7e-60 Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270) 10 20 30 40 50 60 pF1KB7 MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSP 190 200 210 220 230 240 250 260 270 pF1KB7 ASQEDLESEISEDSDQEVDIEGDKSYFNAG :::::::::::::::::::::::::::::: NP_002 ASQEDLESEISEDSDQEVDIEGDKSYFNAG 250 260 270 >>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa) initn: 301 init1: 238 opt: 322 Z-score: 225.0 bits: 49.4 E(85289): 8.6e-06 Smith-Waterman score: 322; 36.3% identity (62.6% similar) in 171 aa overlap (41-204:56-224) 20 30 40 50 60 pF1KB7 GAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTL-PSPNSSFTSLVSPYRTPV : .. :: .: : :.:: .. . :.:. NP_057 SGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAPLPGSSGVGPGGVIRVPA 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB7 YEPTPIHPAFSHHSAAALAAAYG-PGGFGGPLYPFP----RTVNDYTHALLRHDPL-GKP ..: :. : . :. .. : ::..: .:. : ..: : : .:. : NP_057 HRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAAL--SPFSGTR 90 100 110 120 130 140 130 140 150 160 170 180 pF1KB7 LLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKT . :. .: ::: .. :: .:..:::..: ::::. :: ::: :.... :::: NP_057 RIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKT 150 160 170 180 190 200 190 200 210 220 230 240 pF1KB7 WFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQ ::::::.:::: :. .... NP_057 WFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQ 210 220 230 240 250 260 >>NP_068777 (OMIM: 142995) H2.0-like homeobox protein [H (488 aa) initn: 296 init1: 252 opt: 326 Z-score: 224.8 bits: 50.2 E(85289): 8.8e-06 Smith-Waterman score: 326; 32.0% identity (53.7% similar) in 281 aa overlap (2-260:136-406) 10 20 pF1KB7 MQYPHPGPAAGAVGVPL----YAPTPLLQPA : : : : :::. : .:.: . . NP_068 AGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGS 110 120 130 140 150 160 30 40 50 60 70 80 pF1KB7 HPTP------FYIEDILGRGPAAPTPAPTLPSPNSSFTSLVSPYRTPVYEPTPIHPAFSH :.: : :. ::. : : . ..:::.. : :. .: . . NP_068 APAPSSKDLKFGIDRILS---AEFDPKVKEGNTLRDLTSLLTGGR-----PAGVHLSGLQ 170 180 190 200 210 90 100 110 120 130 pF1KB7 HSAAALAAAYGP----GGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFL-QRPLHK ::. . :. : ... .:: :: :. : . : .: . . : .: NP_068 PSAGQFFASLDPINEASAILSPLNSNPR--NSVQHQFQDTFPGPYAVLTKDTMPQTYKRK 220 230 240 250 260 270 140 150 160 170 180 190 pF1KB7 RKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLK :. ... ::: : :::.:: :::.. :.::.:: :: :.. :::.:::::: :::. : NP_068 RSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSK 280 290 300 310 320 330 200 210 220 230 240 pF1KB7 QENPQSNKKEELESLDS----SCDQRQDL--PSEQNKGASLDSSQCSPSPASQEDLE-SE . . :..: .: : . : .:: ::... : .::. . : : .: NP_068 EAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTE 340 350 360 370 380 390 250 260 270 pF1KB7 ISEDSDQEVDIEGDKSYFNAG :: : ... . NP_068 GSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSL 400 410 420 430 440 450 >>NP_004088 (OMIM: 600034) homeobox protein EMX1 [Homo s (290 aa) initn: 259 init1: 190 opt: 296 Z-score: 208.6 bits: 46.4 E(85289): 7.1e-05 Smith-Waterman score: 299; 31.5% identity (56.8% similar) in 241 aa overlap (7-232:58-285) 10 20 30 pF1KB7 MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIED : ..:..: : : . .: .:: . NP_004 APAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEPLRPTALNYPH 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 ILGRGPAAPTPAPTLPSPNSSFTSL-VSPYRTP--VYEPTPIHPAFSHHSAAALAAA--Y :.: : . : .. .. : : : :. . :::.. : : :.:. NP_004 -----PSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGASPLQ 90 100 110 120 130 140 100 110 120 130 140 pF1KB7 GPGGFGG-----PLYPFPRTVND--YTHALLRHD-PLGKPLLWSPFLQRPLHKRKGGQVR : .: : ::. .: .. . . : . : : :: .:: ..: . : . NP_004 PPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTA---- 150 160 170 180 190 150 160 170 180 190 200 pF1KB7 FSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRR--LKQENPQ :: .: ..::. :: ..:. :::.:: :.::: :::.::::::.:..: :..:.:. NP_004 FSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPE 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB7 SNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQEVDIE :..:.. : .: . ..: .: ..: NP_004 SEQKKK----GSHHINRWRIATKQANGEDIDVTSND 260 270 280 290 270 pF1KB7 GDKSYFNAG >>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa) initn: 356 init1: 239 opt: 285 Z-score: 201.6 bits: 45.2 E(85289): 0.00017 Smith-Waterman score: 316; 32.0% identity (53.2% similar) in 231 aa overlap (2-206:8-235) 10 20 30 40 50 pF1KB7 MQYPHPG-PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPS : ::: : . .. : .: :: : . :: :: . :. : :: NP_066 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPA-PRGPDGASYLG-GPPGGRPGATYPS 10 20 30 40 50 60 70 80 90 pF1KB7 PNSSFTSLVSPY------------------RTPVYEPTP--IHPAFSHHSAAALAAAYGP .::..: .:. :.:...: : . : . . :. .. NP_066 LPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPS-ALPAMPSVPTV 60 70 80 90 100 110 100 110 120 130 140 pF1KB7 GGFGGPLYPFP----RTVNDYTHALLRHDPLGKPL-LWSPFLQRPLHKRKGGQVRFSNDQ ...:: .:. : :.: : :. . :. .: ::: .. :: : NP_066 SSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQ 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB7 TIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEEL ::::.:. ::::. :: ::: :.... ::::::::::.:::: :. ...... NP_066 ICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQAS 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 ESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQEVDIEGDKSYFN NP_066 RLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV 240 250 260 270 280 290 >>NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 [Hom (367 aa) initn: 280 init1: 231 opt: 276 Z-score: 194.8 bits: 44.2 E(85289): 0.00041 Smith-Waterman score: 297; 32.0% identity (51.2% similar) in 297 aa overlap (5-257:68-337) 10 20 30 pF1KB7 MQYPHPG----PAAGAVGVPLYAPTPLLQPAHPT .:: ::.:... : .: :. : : NP_006 AAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLS-SLGSPPQQLSAA--T 40 50 60 70 80 90 40 50 60 70 80 pF1KB7 PFYIEDILGRGPAAPTPA-PTLPSPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAA : :.:::.: :. :. . .::: . : .: : . . . : .::: :: NP_006 PHGINDILSR-PSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAA----AAAAAAA 100 110 120 130 140 90 100 110 120 130 pF1KB7 AYGPGGF--GGP----LYPFPRTVNDY-------THALLRHD-PLGK-----PLLWSPFL : .:.:. : : : : : . : . :. :. ::.. :..: . NP_006 ASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVM 150 160 170 180 190 200 140 150 160 170 pF1KB7 QRPL----------H----------KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRL : : : ::: . ::..: . ::: :: :::. ::: :: NP_006 QSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARL 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB7 AKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGAS : : ..: :::.::::::.:::. . . . :: .:: .:. :::: NP_006 AYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKK------------KQDSETERLKGAS 270 280 290 300 310 240 250 260 270 pF1KB7 LDSSQCSPSPASQEDLESEISEDSDQEVDIEGDKSYFNAG . . ..: .. .. .::.: NP_006 ENEEE-------DDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHASEPESSS 320 330 340 350 360 >>NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 isof (234 aa) initn: 266 init1: 220 opt: 259 Z-score: 186.4 bits: 42.0 E(85289): 0.0012 Smith-Waterman score: 292; 35.4% identity (53.1% similar) in 254 aa overlap (4-241:7-232) 10 20 30 40 50 pF1KB7 MQYPHPGPAAGAVGVPLYAPTPLLQPAHP-TPFYIEDILGRGPAAPTPAPTLPSPNS :.:: : . ..: :: :..: : : :.::: : : . .: NP_006 MLRVPEPRPGEAKAEGAAP---PT----PSKPLTSFLIQDILRDG------AQRQGGRTS 10 20 30 40 60 70 80 90 100 110 pF1KB7 SFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLR : . : : :: : .: .. :.: . : ::.. . ...: . NP_006 S-----QRQRDPEPEPEP-EPEGGRSRAGAQNDQLSTG---------PRAAPEEAETLAE 50 60 70 80 90 120 130 140 150 160 pF1KB7 HDP---LGKPLLWS-------PFL-QRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPP .: ::. :: : : : : : . .: ... ::. :.::::.:: ::::: : NP_006 TEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAP 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB7 ERKRLAKMLQLSERQVKTWFQNRRAKWRR--LKQENPQSNKKEELESLDSSCDQRQDLPS :: .::: :.:.: ::: :::::: : .: :..: . .:. : .: .: .: : NP_006 ERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVS 160 170 180 190 200 210 230 240 250 260 270 pF1KB7 EQNKGASLDSSQC--SPSPASQEDLESEISEDSDQEVDIEGDKSYFNAG :. : : ::: NP_006 VYNSYPYYPYLYCVGSWSPAFW 220 230 >>XP_011538046 (OMIM: 186770) PREDICTED: T-cell leukemia (342 aa) initn: 265 init1: 213 opt: 258 Z-score: 183.8 bits: 42.1 E(85289): 0.0017 Smith-Waterman score: 263; 28.4% identity (55.1% similar) in 236 aa overlap (6-224:82-306) 10 20 30 pF1KB7 MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIE :: ::. :. ..: . .. XP_011 GGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLT-------GSYNVN 60 70 80 90 100 40 50 60 70 80 pF1KB7 DILGRGPAAPTPAPTLPSPNSSFTSLVSPYRTPVYEPTP---IHP---AFSHHSAAALAA :. ::. . . : ... : .. :.:...: :: : . .. .. : XP_011 MALAGGPGPGGGGGS--SGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPA 110 120 130 140 150 160 90 100 110 120 130 140 pF1KB7 AYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWS-----PFLQRPLHKRKGGQVRF : ... : .:. .. ::. : .:. . :. .: :.: .. : XP_011 MPGVNNLTGLTFPWMESNRRYTKD--RFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSF 170 180 190 200 210 220 150 160 170 180 190 200 pF1KB7 SNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNK . : ::::.:. ::::. :: ::: :.... ::::::::::.:::: :. .... XP_011 TRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAER 230 240 250 260 270 280 210 220 230 240 250 pF1KB7 KEE---LESLDSSCDQR---QDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQEV .. : .:.. :. : ::.. XP_011 QQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASA 290 300 310 320 330 340 >>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa) initn: 247 init1: 171 opt: 257 Z-score: 183.6 bits: 41.9 E(85289): 0.0017 Smith-Waterman score: 272; 27.8% identity (52.0% similar) in 273 aa overlap (2-250:59-320) 10 20 pF1KB7 MQYPHPG----PAAGAVGV-----PLYAPTP : :: : :.:. . : : :. NP_002 SGGADGGPGGGPGYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREPAY-PAA 30 40 50 60 70 80 30 40 50 60 70 pF1KB7 LLQPAHPTPFYIEDILGRGPAAP--TPAPTLP-----SPNSSF--TSLVSPYRTPVYEPT : ::: . :: :.: : : : .: .. . ...: : .: NP_002 ALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQLPPPLQPR 90 100 110 120 130 140 80 90 100 110 120 130 pF1KB7 PIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLR-HDPLGKPLLWSPFLQR . :: .. :: :. :.: ..: :. . : . :. ..:. : . . .. NP_002 AVPPAAPRRCEAAPATPGVPAGGSAPACPL--LLADKSPLGLKGKEPVVYPWMKKIHVSA 150 160 170 180 190 200 140 150 160 170 180 pF1KB7 PLHKRKGGQVR-----FSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQN . .::. . .. .:..::::.:. ..::. .: ..:. : ::::::: :::: NP_002 VNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQN 210 220 230 240 250 260 190 200 210 220 230 240 pF1KB7 RRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLE :: :: :... : : ..: .:. . . :... : : :... . NP_002 RRMKW---KKDHKLPNTK--MRSSNSASASAGPPGKAQTQSPHLHPH---PHPSTSTPVP 270 280 290 300 310 250 260 270 pF1KB7 SEISEDSDQEVDIEGDKSYFNAG : : NP_002 SSI 320 >>NP_001243268 (OMIM: 602041) homeobox protein Nkx-3.1 i (159 aa) initn: 236 init1: 220 opt: 251 Z-score: 183.3 bits: 40.9 E(85289): 0.0018 Smith-Waterman score: 252; 41.9% identity (56.8% similar) in 155 aa overlap (102-241:5-157) 80 90 100 110 120 pF1KB7 PTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALL---RHDPLGKPLLWS- : :: . : : :: ::. :: : NP_001 MLRVPEPRPGEAETLAETEPERH--LGSYLLDSE 10 20 30 130 140 150 160 170 180 pF1KB7 ------PFL-QRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQ : : : : . .: ... ::. :.::::.:: ::::: ::: .::: :.:.: : NP_001 NTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQ 40 50 60 70 80 90 190 200 210 220 230 pF1KB7 VKTWFQNRRAKWRR--LKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQC-- :: :::::: : .: :..: . .:. : .: .: .: : :. : NP_001 VKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVG 100 110 120 130 140 150 240 250 260 270 pF1KB7 SPSPASQEDLESEISEDSDQEVDIEGDKSYFNAG : ::: NP_001 SWSPAFW 270 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:27:13 2016 done: Sat Nov 5 18:27:15 2016 Total Scan time: 8.760 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]