FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7556, 271 aa 1>>>pF1KB7556 271 - 271 aa - 271 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4817+/-0.000751; mu= 4.9743+/- 0.046 mean_var=235.9003+/-47.443, 0's: 0 Z-trim(118.9): 30 B-trim: 468 in 1/52 Lambda= 0.083505 statistics sampled from 19937 (19969) to 19937 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.87), E-opt: 0.2 (0.613), width: 16 Scan time: 2.810 The best scores are: opt bits E(32554) CCDS8121.1 FOSL1 gene_id:8061|Hs108|chr11 ( 271) 1878 237.6 7e-63 CCDS76436.1 FOSL1 gene_id:8061|Hs108|chr11 ( 169) 920 122.0 2.8e-28 CCDS73324.1 FOSL1 gene_id:8061|Hs108|chr11 ( 235) 915 121.6 5.3e-28 CCDS76437.1 FOSL1 gene_id:8061|Hs108|chr11 ( 135) 735 99.6 1.2e-21 CCDS1766.1 FOSL2 gene_id:2355|Hs108|chr2 ( 326) 487 70.1 2.2e-12 CCDS9841.1 FOS gene_id:2353|Hs108|chr14 ( 380) 468 67.9 1.2e-11 >>CCDS8121.1 FOSL1 gene_id:8061|Hs108|chr11 (271 aa) initn: 1878 init1: 1878 opt: 1878 Z-score: 1242.4 bits: 237.6 E(32554): 7e-63 Smith-Waterman score: 1878; 100.0% identity (100.0% similar) in 271 aa overlap (1-271:1-271) 10 20 30 40 50 60 pF1KB7 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST 190 200 210 220 230 240 250 260 270 pF1KB7 PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL ::::::::::::::::::::::::::::::: CCDS81 PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL 250 260 270 >>CCDS76436.1 FOSL1 gene_id:8061|Hs108|chr11 (169 aa) initn: 920 init1: 920 opt: 920 Z-score: 621.2 bits: 122.0 E(32554): 2.8e-28 Smith-Waterman score: 941; 62.4% identity (62.4% similar) in 271 aa overlap (1-271:1-169) 10 20 30 40 50 60 pF1KB7 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG ::::::::::::::::::::::::::::::::: CCDS76 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQ--------------------------- 10 20 30 70 80 90 100 110 120 pF1KB7 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA CCDS76 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB7 KCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE ::::::::::::::::::::::::::::::::::::::::::::: CCDS76 ---------------ETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE 40 50 60 70 190 200 210 220 230 240 pF1KB7 GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST 80 90 100 110 120 130 250 260 270 pF1KB7 PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL ::::::::::::::::::::::::::::::: CCDS76 PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL 140 150 160 >>CCDS73324.1 FOSL1 gene_id:8061|Hs108|chr11 (235 aa) initn: 915 init1: 915 opt: 915 Z-score: 616.2 bits: 121.6 E(32554): 5.3e-28 Smith-Waterman score: 1564; 86.7% identity (86.7% similar) in 271 aa overlap (1-271:1-235) 10 20 30 40 50 60 pF1KB7 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA ::::::::::::::::::::::::::::::::::::::: CCDS73 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQ--------------------- 70 80 90 130 140 150 160 170 180 pF1KB7 KCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE ::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ---------------ETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE 100 110 120 130 140 190 200 210 220 230 240 pF1KB7 GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST 150 160 170 180 190 200 250 260 270 pF1KB7 PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL ::::::::::::::::::::::::::::::: CCDS73 PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL 210 220 230 >>CCDS76437.1 FOSL1 gene_id:8061|Hs108|chr11 (135 aa) initn: 732 init1: 732 opt: 735 Z-score: 502.0 bits: 99.6 E(32554): 1.2e-21 Smith-Waterman score: 735; 77.9% identity (83.6% similar) in 140 aa overlap (1-138:1-135) 10 20 30 40 50 60 pF1KB7 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA ::::::::::::::::::::::::::::::::::::::: . . ..: :. : CCDS76 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQPGGRGAPPSKARAEQ-----A 70 80 90 100 110 130 140 150 160 170 pF1KB7 KCRNRRK--ELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGA : . .. : :: : : : CCDS76 GCGQVQEPEEGTDRLPAGGD 120 130 >>CCDS1766.1 FOSL2 gene_id:2355|Hs108|chr2 (326 aa) initn: 546 init1: 413 opt: 487 Z-score: 335.7 bits: 70.1 E(32554): 2.2e-12 Smith-Waterman score: 746; 46.0% identity (65.2% similar) in 328 aa overlap (1-267:1-322) 10 20 30 40 pF1KB7 MFRDFGEPGP-SSGNGGGYGGPAQPPAAAQAA--QQKFHL---------VPSINTMSGSQ :..:. :: .... :. :.::. . .... ::::.. .:.::... :: CCDS17 MYQDY--PGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQ 10 20 30 40 50 50 60 70 80 90 pF1KB7 ELQWMVQPHFLGPSSYPRPLTYPQYSP-PQ----------PRPGVIRALGPPPGVRRRPC .::::::: . : : : ..: ::: : ::::::...: : ::: CCDS17 DLQWMVQPTVITSMSNPYPRSHP-YSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRD- 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 EQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQ ::.::::::.::.::::::::::::::::.:::. :::::..::.::::::.:: ::::. CCDS17 EQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKE 120 130 140 150 160 170 160 170 180 pF1KB7 KERLELVLEAHRPICKI-PE----------------GAKEG-----------DTGSTSGT ::.::..: :: :.::: :: :.. : :. :.:.. CCDS17 KEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSA 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB7 SSPPAPCRPVPCISLSPGPVLEPEALHTPTLMT-TPSLTPFTPSLVFTYPS-----TP-- . : . ::.. : : : :::: ..: ::..:: : .::::::: .: CCDS17 GLDKAQRSVIKPISIAGGFYGE-EPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPAS 240 250 260 270 280 290 250 260 270 pF1KB7 --EPCASAHRKSSSSSGDPSSDPLGSPTLLAL : :..:::.:::: :: ::: :.::: CCDS17 PSESCSKAHRRSSSS-GDQSSDSLNSPTLLAL 300 310 320 >>CCDS9841.1 FOS gene_id:2353|Hs108|chr14 (380 aa) initn: 677 init1: 422 opt: 468 Z-score: 322.5 bits: 67.9 E(32554): 1.2e-11 Smith-Waterman score: 536; 42.2% identity (65.8% similar) in 237 aa overlap (36-251:59-288) 10 20 30 40 50 60 pF1KB7 GEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG---PS ...:.....: : .:::.::: ... :: CCDS98 YYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSVAPS 30 40 50 60 70 80 70 80 90 100 110 pF1KB7 SY--PRPLTYPQYSP-PQPRPGVIRAL--GPPPGVRRR-PCEQISPEEEERRRVRRERNK . :.:. : : : ::.... : .. :: ::.::::::.::.:::::: CCDS98 QTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNK 90 100 110 120 130 140 120 130 140 150 160 170 pF1KB7 LAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPE .:::::::::.:::: ::::::.::::::.:: :: .: :.::.::..: :::: ::::. CCDS98 MAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPD 150 160 170 180 190 200 180 190 200 210 220 pF1KB7 G---AKEGDTGSTSGTSSPPAPCRP-------VPCISLS-PGPVLEP-EALHTPTLMTTP .: ...: . :.. : : .: .. : : .:: ... . : : : CCDS98 DLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEP 210 220 230 240 250 260 230 240 250 260 270 pF1KB7 SLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL : : .:.. .: .: .: CCDS98 ----FDD---FLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATELE 270 280 290 300 310 320 271 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:40:47 2016 done: Fri Nov 4 08:40:48 2016 Total Scan time: 2.810 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]