FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7561, 207 aa
1>>>pF1KB7561 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8363+/-0.000371; mu= 16.4425+/- 0.023
mean_var=60.7848+/-12.185, 0's: 0 Z-trim(112.3): 59 B-trim: 0 in 0/50
Lambda= 0.164504
statistics sampled from 21067 (21125) to 21067 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.248), width: 16
Scan time: 5.800
The best scores are: opt bits E(85289)
NP_006157 (OMIM: 189904) nuclear transcription fac ( 207) 1341 326.5 1.9e-89
XP_005268967 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 1329 323.6 1.4e-88
XP_005268965 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 1329 323.6 1.4e-88
XP_005268966 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 1329 323.6 1.4e-88
NP_001929 (OMIM: 601482) protein Dr1 [Homo sapiens ( 176) 253 68.2 9.1e-12
NP_001265184 (OMIM: 607267) DNA polymerase epsilon ( 147) 233 63.4 2.1e-10
NP_059139 (OMIM: 607267) DNA polymerase epsilon su ( 147) 233 63.4 2.1e-10
>>NP_006157 (OMIM: 189904) nuclear transcription factor (207 aa)
initn: 1341 init1: 1341 opt: 1341 Z-score: 1726.7 bits: 326.5 E(85289): 1.9e-89
Smith-Waterman score: 1341; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)
10 20 30 40 50 60
pF1KB7 MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 IANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLIT
130 140 150 160 170 180
190 200
pF1KB7 TDGQQQNVMVYTTSYQQISGVQQIQFS
:::::::::::::::::::::::::::
NP_006 TDGQQQNVMVYTTSYQQISGVQQIQFS
190 200
>>XP_005268967 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa)
initn: 1329 init1: 1329 opt: 1329 Z-score: 1711.3 bits: 323.6 E(85289): 1.4e-88
Smith-Waterman score: 1329; 100.0% identity (100.0% similar) in 205 aa overlap (3-207:4-208)
10 20 30 40 50
pF1KB7 MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNLMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 PIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 FAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLI
130 140 150 160 170 180
180 190 200
pF1KB7 TTDGQQQNVMVYTTSYQQISGVQQIQFS
::::::::::::::::::::::::::::
XP_005 TTDGQQQNVMVYTTSYQQISGVQQIQFS
190 200
>>XP_005268965 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa)
initn: 1329 init1: 1329 opt: 1329 Z-score: 1711.3 bits: 323.6 E(85289): 1.4e-88
Smith-Waterman score: 1329; 100.0% identity (100.0% similar) in 205 aa overlap (3-207:4-208)
10 20 30 40 50
pF1KB7 MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNLMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 PIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 FAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLI
130 140 150 160 170 180
180 190 200
pF1KB7 TTDGQQQNVMVYTTSYQQISGVQQIQFS
::::::::::::::::::::::::::::
XP_005 TTDGQQQNVMVYTTSYQQISGVQQIQFS
190 200
>>XP_005268966 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa)
initn: 1329 init1: 1329 opt: 1329 Z-score: 1711.3 bits: 323.6 E(85289): 1.4e-88
Smith-Waterman score: 1329; 100.0% identity (100.0% similar) in 205 aa overlap (3-207:4-208)
10 20 30 40 50
pF1KB7 MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNLMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 PIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 FAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLI
130 140 150 160 170 180
180 190 200
pF1KB7 TTDGQQQNVMVYTTSYQQISGVQQIQFS
::::::::::::::::::::::::::::
XP_005 TTDGQQQNVMVYTTSYQQISGVQQIQFS
190 200
>>NP_001929 (OMIM: 601482) protein Dr1 [Homo sapiens] (176 aa)
initn: 236 init1: 195 opt: 253 Z-score: 332.2 bits: 68.2 E(85289): 9.1e-12
Smith-Waterman score: 253; 31.6% identity (65.8% similar) in 155 aa overlap (54-207:8-154)
30 40 50 60 70 80
pF1KB7 GSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAK
..:. .: : . ...:...:.. ..:.::.
NP_001 MASSSGNDDDLTIPRAAINKMIKETLPNV-RVANDAR
10 20 30
90 100 110 120 130 140
pF1KB7 ECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFRE
: : .: .::: .:.:::.: :.. ..:::. : .. :. .::: ::. .: ::. .
NP_001 ELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKT
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB7 -AMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ
:.: .: : . ..:. . :: . : :.. ::: .. :. ...:
NP_001 VALKRRK----ASSRLENLG--IPEEELLRQQQE-LFAKARQQQAELAQQEWLQMQQAAQ
100 110 120 130 140
pF1KB7 QIQFS
: :..
NP_001 QAQLAAASASASNQAGSSQDEEDDDDI
150 160 170
>>NP_001265184 (OMIM: 607267) DNA polymerase epsilon sub (147 aa)
initn: 233 init1: 217 opt: 233 Z-score: 307.7 bits: 63.4 E(85289): 2.1e-10
Smith-Waterman score: 233; 38.1% identity (71.1% similar) in 97 aa overlap (53-149:4-100)
30 40 50 60 70 80
pF1KB7 GGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDA
: .:. :: : ..::.:.:.:. .:.:.:
NP_001 MAERPEDLNLPNAVITRIIKEALPDGVNISKEA
10 20 30
90 100 110 120 130 140
pF1KB7 KECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFR
. ... .: :. . :: :.. . ::::.:. :.: :: . :. .: ::: :. .:
NP_001 RSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB7 EAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ
. .::.:
NP_001 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN
100 110 120 130 140
>>NP_059139 (OMIM: 607267) DNA polymerase epsilon subuni (147 aa)
initn: 233 init1: 217 opt: 233 Z-score: 307.7 bits: 63.4 E(85289): 2.1e-10
Smith-Waterman score: 233; 38.1% identity (71.1% similar) in 97 aa overlap (53-149:4-100)
30 40 50 60 70 80
pF1KB7 GGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDA
: .:. :: : ..::.:.:.:. .:.:.:
NP_059 MAERPEDLNLPNAVITRIIKEALPDGVNISKEA
10 20 30
90 100 110 120 130 140
pF1KB7 KECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFR
. ... .: :. . :: :.. . ::::.:. :.: :: . :. .: ::: :. .:
NP_059 RSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB7 EAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ
. .::.:
NP_059 REQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN
100 110 120 130 140
207 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:42:34 2016 done: Fri Nov 4 08:42:35 2016
Total Scan time: 5.800 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]