FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7562, 274 aa 1>>>pF1KB7562 274 - 274 aa - 274 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0202+/-0.000305; mu= -4.6146+/- 0.019 mean_var=264.8467+/-53.363, 0's: 0 Z-trim(125.3): 13 B-trim: 27 in 1/57 Lambda= 0.078809 statistics sampled from 48702 (48720) to 48702 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.856), E-opt: 0.2 (0.571), width: 16 Scan time: 8.280 The best scores are: opt bits E(85289) NP_612465 (OMIM: 614983) basic leucine zipper tran ( 274) 1905 228.6 1e-59 NP_001287736 (OMIM: 614983) basic leucine zipper t ( 250) 1595 193.3 3.8e-49 NP_001287737 (OMIM: 614983) basic leucine zipper t ( 189) 1325 162.5 5.3e-40 NP_061134 (OMIM: 612470) basic leucine zipper tran ( 127) 249 40.0 0.0026 NP_006390 (OMIM: 612476) basic leucine zipper tran ( 125) 244 39.5 0.0038 >>NP_612465 (OMIM: 614983) basic leucine zipper transcri (274 aa) initn: 1905 init1: 1905 opt: 1905 Z-score: 1193.2 bits: 228.6 E(85289): 1e-59 Smith-Waterman score: 1905; 100.0% identity (100.0% similar) in 274 aa overlap (1-274:1-274) 10 20 30 40 50 60 pF1KB7 MHLCGGNGLLTQTDPKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHESLEKDNLALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 MHLCGGNGLLTQTDPKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHESLEKDNLALR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQHGCREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 KEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQHGCREQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPLLFASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 LELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPLLFASH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TGSSLQGSSSKLSALQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARLQSREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 TGSSLQGSSSKLSALQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARLQSREH 190 200 210 220 230 240 250 260 270 pF1KB7 KPALSAATWQGLVVDPSPHPLLAFPLLSSAQVHF :::::::::::::::::::::::::::::::::: NP_612 KPALSAATWQGLVVDPSPHPLLAFPLLSSAQVHF 250 260 270 >>NP_001287736 (OMIM: 614983) basic leucine zipper trans (250 aa) initn: 1595 init1: 1595 opt: 1595 Z-score: 1003.3 bits: 193.3 E(85289): 3.8e-49 Smith-Waterman score: 1595; 99.1% identity (99.6% similar) in 230 aa overlap (45-274:21-250) 20 30 40 50 60 70 pF1KB7 PKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHESLEKDNLALRKEIQSLQAELAWWS . :::::::::::::::::::::::::::: NP_001 MAPVGKRIGGLGDTRVGGPCISQQHESLEKDNLALRKEIQSLQAELAWWS 10 20 30 40 50 80 90 100 110 120 130 pF1KB7 RTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQHGCREQLELFQTPGSCYPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQHGCREQLELFQTPGSCYPAQ 60 70 80 90 100 110 140 150 160 170 180 190 pF1KB7 PLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPLLFASHTGSSLQGSSSKLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPLLFASHTGSSLQGSSSKLSA 120 130 140 150 160 170 200 210 220 230 240 250 pF1KB7 LQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARLQSREHKPALSAATWQGLVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARLQSREHKPALSAATWQGLVV 180 190 200 210 220 230 260 270 pF1KB7 DPSPHPLLAFPLLSSAQVHF :::::::::::::::::::: NP_001 DPSPHPLLAFPLLSSAQVHF 240 250 >>NP_001287737 (OMIM: 614983) basic leucine zipper trans (189 aa) initn: 1325 init1: 1325 opt: 1325 Z-score: 839.1 bits: 162.5 E(85289): 5.3e-40 Smith-Waterman score: 1325; 100.0% identity (100.0% similar) in 189 aa overlap (86-274:1-189) 60 70 80 90 100 110 pF1KB7 NLALRKEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQH :::::::::::::::::::::::::::::: NP_001 MDCASCSAPGLLGCWDQAEGLLGPGPQGQH 10 20 30 120 130 140 150 160 170 pF1KB7 GCREQLELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCREQLELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPL 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB7 LFASHTGSSLQGSSSKLSALQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFASHTGSSLQGSSSKLSALQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARL 100 110 120 130 140 150 240 250 260 270 pF1KB7 QSREHKPALSAATWQGLVVDPSPHPLLAFPLLSSAQVHF ::::::::::::::::::::::::::::::::::::::: NP_001 QSREHKPALSAATWQGLVVDPSPHPLLAFPLLSSAQVHF 160 170 180 >>NP_061134 (OMIM: 612470) basic leucine zipper transcri (127 aa) initn: 247 init1: 224 opt: 249 Z-score: 180.4 bits: 40.0 E(85289): 0.0026 Smith-Waterman score: 249; 47.4% identity (84.2% similar) in 76 aa overlap (12-86:29-104) 10 20 30 40 pF1KB7 MHLCGGNGLLTQTDPKEQQRQLKK-QKNRAAAQRSRQKHTDKA : .:....:.... .:::.::::::.:.:.:: NP_061 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 DALHQQHESLEKDNLALRKEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQ : ::...::::..: ::.:: .: :: ...:. ::..::. NP_061 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 AEGLLGPGPQGQHGCREQLELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAV NP_061 VAGCLPR >>NP_006390 (OMIM: 612476) basic leucine zipper transcri (125 aa) initn: 244 init1: 230 opt: 244 Z-score: 177.4 bits: 39.5 E(85289): 0.0038 Smith-Waterman score: 244; 47.0% identity (74.7% similar) in 83 aa overlap (12-94:21-103) 10 20 30 40 50 pF1KB7 MHLCGGNGLLTQTDPKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHES : . . .: ...::: :::.:::..:.:::.:: . :. NP_006 MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 LEKDNLALRKEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGP :::.: ::::::..: :: ... .:. :: :: . :: .: NP_006 LEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 QGQHGCREQLELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLS NP_006 PRFQP 274 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:43:03 2016 done: Fri Nov 4 08:43:04 2016 Total Scan time: 8.280 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]