FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7565, 209 aa 1>>>pF1KB7565 209 - 209 aa - 209 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.9890+/-0.000864; mu= 4.3807+/- 0.052 mean_var=243.5392+/-48.521, 0's: 0 Z-trim(115.8): 46 B-trim: 117 in 1/52 Lambda= 0.082184 statistics sampled from 16352 (16393) to 16352 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.504), width: 16 Scan time: 2.390 The best scores are: opt bits E(32554) CCDS3816.1 HMGB2 gene_id:3148|Hs108|chr4 ( 209) 1431 181.3 3.7e-46 CCDS9335.1 HMGB1 gene_id:3146|Hs108|chr13 ( 215) 1182 151.8 2.9e-37 CCDS35428.1 HMGB3 gene_id:3149|Hs108|chrX ( 200) 1016 132.1 2.3e-31 CCDS2477.1 SP100 gene_id:6672|Hs108|chr2 ( 879) 865 114.9 1.5e-25 CCDS30668.1 HMGB4 gene_id:127540|Hs108|chr1 ( 186) 540 75.6 2.2e-14 >>CCDS3816.1 HMGB2 gene_id:3148|Hs108|chr4 (209 aa) initn: 1431 init1: 1431 opt: 1431 Z-score: 942.2 bits: 181.3 E(32554): 3.7e-46 Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS38 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::::::::::::::::::::::::::: CCDS38 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>CCDS9335.1 HMGB1 gene_id:3146|Hs108|chr13 (215 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 782.5 bits: 151.8 E(32554): 2.9e-37 Smith-Waterman score: 1182; 81.3% identity (94.3% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF ::::::.::::::::::::::::::::::::::.::::.::::::::::::::::::.:: CCDS93 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::.:::::.::::.:.::::. : : :::::::::::::::::::.:::::.::::: CCDS93 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. .: ::::::.::::::::::::::::::::: .:.::: . CCDS93 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::.: :..::.::.:.:.:.::::::: CCDS93 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 190 200 210 >>CCDS35428.1 HMGB3 gene_id:3149|Hs108|chrX (200 aa) initn: 1151 init1: 494 opt: 1016 Z-score: 676.5 bits: 132.1 E(32554): 2.3e-31 Smith-Waterman score: 1016; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:1-200) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :.::::.::.::::.:::::::::::::::.:. ::::::::::::::::::.:::::: CCDS35 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL ..:::.::.:::::::.: : :: :: ::::::::::::.::::::: :::::: .::. CCDS35 DEMAKADKVRYDREMKDYGPAKGGKK--KKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGI 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. . ..:::: ::::::::::::.: :..::: . : :::.. CCDS35 SIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFD-GAKGPAKV-- 120 130 140 150 160 170 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ..:: : ::::::::::.: :::::: CCDS35 ARKKVEEEDEEEEEEEEEE-EEEEDE 180 190 200 >>CCDS2477.1 SP100 gene_id:6672|Hs108|chr2 (879 aa) initn: 1151 init1: 847 opt: 865 Z-score: 572.1 bits: 114.9 E(32554): 1.5e-25 Smith-Waterman score: 865; 66.7% identity (84.6% similar) in 201 aa overlap (8-208:683-879) 10 20 30 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVN : : : .:. : ::::::.::.::. CCDS24 KNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPC-EEHKKKNPDASVK 660 670 680 690 700 710 40 50 60 70 80 90 pF1KB7 FAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKR :.:: ::::: :::. ::::.:::::::.:::.:.::::.:.::::.:: : :::::::: CCDS24 FSEFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKGEKKKKFKDPNAPKR 720 730 740 750 760 770 100 110 120 130 140 150 pF1KB7 PPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEK :: ::::::::.:::::.::::::: :..:::. ::.. .: ::: ::.:::::::::.: CCDS24 PPLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKK 780 790 800 810 820 830 160 170 180 190 200 pF1KB7 DIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDEDEEEEDEDEE :::::::::: ...:: . ::::.: :::.::.:.:.:.:::.:. CCDS24 DIAAYRAKGKPNSAKKRVVKAEKSKKKKE---EEEDEEDEQEEENEEDDDK 840 850 860 870 >>CCDS30668.1 HMGB4 gene_id:127540|Hs108|chr1 (186 aa) initn: 544 init1: 279 opt: 540 Z-score: 371.8 bits: 75.6 E(32554): 2.2e-14 Smith-Waterman score: 540; 45.5% identity (77.6% similar) in 165 aa overlap (1-165:1-163) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF ::: ::....:::. :. . :.. :...:.. :.: :::.::::.:...: .::.:. CCDS30 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL : .:: :::::..:: ::: . :: .:.::. :.::::.:.:::..: ..: :.:. CCDS30 EALAKLDKARYQEEMMNYVGKR--KKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNW 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG :. ..:: :.::: . .:.::::..: :. :: ... :: . CCDS30 SVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRC 120 130 140 150 160 170 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE CCDS30 RGKRVRQS 180 209 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:44:49 2016 done: Fri Nov 4 08:44:49 2016 Total Scan time: 2.390 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]