FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7565, 209 aa 1>>>pF1KB7565 209 - 209 aa - 209 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6700+/-0.00034; mu= -0.1724+/- 0.021 mean_var=257.8198+/-51.752, 0's: 0 Z-trim(123.6): 94 B-trim: 338 in 1/56 Lambda= 0.079876 statistics sampled from 43655 (43759) to 43655 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.513), width: 16 Scan time: 6.760 The best scores are: opt bits E(85289) NP_001124160 (OMIM: 163906) high mobility group pr ( 209) 1431 176.8 2.2e-44 NP_001124161 (OMIM: 163906) high mobility group pr ( 209) 1431 176.8 2.2e-44 NP_002120 (OMIM: 163906) high mobility group prote ( 209) 1431 176.8 2.2e-44 NP_001300821 (OMIM: 163905) high mobility group pr ( 215) 1182 148.1 9.9e-36 NP_002119 (OMIM: 163905) high mobility group prote ( 215) 1182 148.1 9.9e-36 NP_001300822 (OMIM: 163905) high mobility group pr ( 215) 1182 148.1 9.9e-36 NP_001288157 (OMIM: 300193,300915) high mobility g ( 200) 1016 129.0 5.4e-30 NP_005333 (OMIM: 300193,300915) high mobility grou ( 200) 1016 129.0 5.4e-30 NP_001288158 (OMIM: 300193,300915) high mobility g ( 200) 1016 129.0 5.4e-30 NP_001288160 (OMIM: 300193,300915) high mobility g ( 220) 1016 129.0 5.8e-30 NP_003104 (OMIM: 604585) nuclear autoantigen Sp-10 ( 879) 865 112.2 2.6e-24 NP_003137 (OMIM: 604328) FACT complex subunit SSRP ( 709) 294 46.3 0.00014 XP_016873669 (OMIM: 604328) PREDICTED: FACT comple ( 843) 294 46.4 0.00016 NP_001092266 (OMIM: 611163) TOX high mobility grou ( 464) 248 40.8 0.0042 NP_116272 (OMIM: 611163) TOX high mobility group b ( 464) 248 40.8 0.0042 NP_001092267 (OMIM: 611163) TOX high mobility grou ( 506) 248 40.9 0.0045 XP_006723947 (OMIM: 611163) PREDICTED: TOX high mo ( 515) 248 40.9 0.0046 XP_016869574 (OMIM: 606863) PREDICTED: thymocyte s ( 504) 242 40.2 0.0073 NP_055544 (OMIM: 606863) thymocyte selection-assoc ( 526) 242 40.2 0.0075 XP_011521304 (OMIM: 611416) PREDICTED: TOX high mo ( 553) 239 39.9 0.0098 >>NP_001124160 (OMIM: 163906) high mobility group protei (209 aa) initn: 1431 init1: 1431 opt: 1431 Z-score: 917.7 bits: 176.8 E(85289): 2.2e-44 Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::::::::::::::::::::::::::: NP_001 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_001124161 (OMIM: 163906) high mobility group protei (209 aa) initn: 1431 init1: 1431 opt: 1431 Z-score: 917.7 bits: 176.8 E(85289): 2.2e-44 Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::::::::::::::::::::::::::: NP_001 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_002120 (OMIM: 163906) high mobility group protein B (209 aa) initn: 1431 init1: 1431 opt: 1431 Z-score: 917.7 bits: 176.8 E(85289): 2.2e-44 Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::::::::::::::::::::::::::: NP_002 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_001300821 (OMIM: 163905) high mobility group protei (215 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 762.4 bits: 148.1 E(85289): 9.9e-36 Smith-Waterman score: 1182; 81.3% identity (94.3% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF ::::::.::::::::::::::::::::::::::.::::.::::::::::::::::::.:: NP_001 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::.:::::.::::.:.::::. : : :::::::::::::::::::.:::::.::::: NP_001 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. .: ::::::.::::::::::::::::::::: .:.::: . NP_001 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::.: :..::.::.:.:.:.::::::: NP_001 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 190 200 210 >>NP_002119 (OMIM: 163905) high mobility group protein B (215 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 762.4 bits: 148.1 E(85289): 9.9e-36 Smith-Waterman score: 1182; 81.3% identity (94.3% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF ::::::.::::::::::::::::::::::::::.::::.::::::::::::::::::.:: NP_002 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::.:::::.::::.:.::::. : : :::::::::::::::::::.:::::.::::: NP_002 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. .: ::::::.::::::::::::::::::::: .:.::: . NP_002 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::.: :..::.::.:.:.:.::::::: NP_002 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 190 200 210 >>NP_001300822 (OMIM: 163905) high mobility group protei (215 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 762.4 bits: 148.1 E(85289): 9.9e-36 Smith-Waterman score: 1182; 81.3% identity (94.3% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF ::::::.::::::::::::::::::::::::::.::::.::::::::::::::::::.:: NP_001 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL :::::.:::::.::::.:.::::. : : :::::::::::::::::::.:::::.::::: NP_001 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. .: ::::::.::::::::::::::::::::: .:.::: . NP_001 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEK 130 140 150 160 170 180 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ::::.: :..::.::.:.:.:.::::::: NP_001 SKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 190 200 210 >>NP_001288157 (OMIM: 300193,300915) high mobility group (200 aa) initn: 1151 init1: 494 opt: 1016 Z-score: 659.5 bits: 129.0 E(85289): 5.4e-30 Smith-Waterman score: 1016; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:1-200) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :.::::.::.::::.:::::::::::::::.:. ::::::::::::::::::.:::::: NP_001 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL ..:::.::.:::::::.: : :: :: ::::::::::::.::::::: :::::: .::. NP_001 DEMAKADKVRYDREMKDYGPAKGGKK--KKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGI 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. . ..:::: ::::::::::::.: :..::: . : :::.. NP_001 SIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFD-GAKGPAKV-- 120 130 140 150 160 170 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ..:: : ::::::::::.: :::::: NP_001 ARKKVEEEDEEEEEEEEEE-EEEEDE 180 190 200 >>NP_005333 (OMIM: 300193,300915) high mobility group pr (200 aa) initn: 1151 init1: 494 opt: 1016 Z-score: 659.5 bits: 129.0 E(85289): 5.4e-30 Smith-Waterman score: 1016; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:1-200) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :.::::.::.::::.:::::::::::::::.:. ::::::::::::::::::.:::::: NP_005 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL ..:::.::.:::::::.: : :: :: ::::::::::::.::::::: :::::: .::. NP_005 DEMAKADKVRYDREMKDYGPAKGGKK--KKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGI 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. . ..:::: ::::::::::::.: :..::: . : :::.. NP_005 SIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFD-GAKGPAKV-- 120 130 140 150 160 170 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ..:: : ::::::::::.: :::::: NP_005 ARKKVEEEDEEEEEEEEEE-EEEEDE 180 190 200 >>NP_001288158 (OMIM: 300193,300915) high mobility group (200 aa) initn: 1151 init1: 494 opt: 1016 Z-score: 659.5 bits: 129.0 E(85289): 5.4e-30 Smith-Waterman score: 1016; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:1-200) 10 20 30 40 50 60 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF :.::::.::.::::.:::::::::::::::.:. ::::::::::::::::::.:::::: NP_001 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL ..:::.::.:::::::.: : :: :: ::::::::::::.::::::: :::::: .::. NP_001 DEMAKADKVRYDREMKDYGPAKGGKK--KKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGI 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG ::::.::::::::.. . ..:::: ::::::::::::.: :..::: . : :::.. NP_001 SIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFD-GAKGPAKV-- 120 130 140 150 160 170 190 200 pF1KB7 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE ..:: : ::::::::::.: :::::: NP_001 ARKKVEEEDEEEEEEEEEE-EEEEDE 180 190 200 >>NP_001288160 (OMIM: 300193,300915) high mobility group (220 aa) initn: 1151 init1: 494 opt: 1016 Z-score: 658.9 bits: 129.0 E(85289): 5.8e-30 Smith-Waterman score: 1016; 74.3% identity (88.8% similar) in 206 aa overlap (1-206:21-220) 10 20 30 40 pF1KB7 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAE :.::::.::.::::.:::::::::::::::.:. ::::: NP_001 MQRMEILPARKRNPFIIRIRMAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 FSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPS :::::::::::::.::::::..:::.::.:::::::.: : :: :: :::::::::::: NP_001 FSKKCSERWKTMSGKEKSKFDEMAKADKVRYDREMKDYGPAKGGKK--KKDPNAPKRPPS 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 AFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIA .::::::: :::::: .::.::::.::::::::.. . ..:::: ::::::::::::.: NP_001 GFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVA 120 130 140 150 160 170 170 180 190 200 pF1KB7 AYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDEDEEEEDEDEE :..::: . : :::.. ..:: : ::::::::::.: :::::: NP_001 DYKSKGKFD-GAKGPAKV--ARKKVEEEDEEEEEEEEEE-EEEEDE 180 190 200 210 220 209 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:44:49 2016 done: Fri Nov 4 08:44:50 2016 Total Scan time: 6.760 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]