FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7573, 212 aa 1>>>pF1KB7573 212 - 212 aa - 212 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1019+/-0.000351; mu= 14.3230+/- 0.022 mean_var=57.1635+/-11.764, 0's: 0 Z-trim(113.2): 15 B-trim: 11 in 1/57 Lambda= 0.169635 statistics sampled from 22448 (22460) to 22448 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.263), width: 16 Scan time: 5.340 The best scores are: opt bits E(85289) NP_004266 (OMIM: 612915) mediator of RNA polymeras ( 212) 1425 356.8 1.5e-98 NP_001292385 (OMIM: 612915) mediator of RNA polyme ( 150) 1022 258.1 5.6e-69 NP_001292384 (OMIM: 612915) mediator of RNA polyme ( 150) 1022 258.1 5.6e-69 NP_001292386 (OMIM: 612915) mediator of RNA polyme ( 123) 767 195.6 2.9e-50 >>NP_004266 (OMIM: 612915) mediator of RNA polymerase II (212 aa) initn: 1425 init1: 1425 opt: 1425 Z-score: 1890.1 bits: 356.8 E(85289): 1.5e-98 Smith-Waterman score: 1425; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KB7 MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRH 130 140 150 160 170 180 190 200 210 pF1KB7 DAVYGPADTMVQYMELFNKIRKQQQVPVAGIR :::::::::::::::::::::::::::::::: NP_004 DAVYGPADTMVQYMELFNKIRKQQQVPVAGIR 190 200 210 >>NP_001292385 (OMIM: 612915) mediator of RNA polymerase (150 aa) initn: 1022 init1: 1022 opt: 1022 Z-score: 1359.4 bits: 258.1 E(85289): 5.6e-69 Smith-Waterman score: 1022; 100.0% identity (100.0% similar) in 150 aa overlap (63-212:1-150) 40 50 60 70 80 90 pF1KB7 AEKQGTFCVDCETYHTAASTLGSQGQTGKLMYVMHNSEYPLSCFALFENGPCLIADTNFD :::::::::::::::::::::::::::::: NP_001 MYVMHNSEYPLSCFALFENGPCLIADTNFD 10 20 30 100 110 120 130 140 150 pF1KB7 VLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASD 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB7 CWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYGPADTMVQYMELFNKIRKQQQVPVAGIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYGPADTMVQYMELFNKIRKQQQVPVAGIR 100 110 120 130 140 150 >>NP_001292384 (OMIM: 612915) mediator of RNA polymerase (150 aa) initn: 1022 init1: 1022 opt: 1022 Z-score: 1359.4 bits: 258.1 E(85289): 5.6e-69 Smith-Waterman score: 1022; 100.0% identity (100.0% similar) in 150 aa overlap (63-212:1-150) 40 50 60 70 80 90 pF1KB7 AEKQGTFCVDCETYHTAASTLGSQGQTGKLMYVMHNSEYPLSCFALFENGPCLIADTNFD :::::::::::::::::::::::::::::: NP_001 MYVMHNSEYPLSCFALFENGPCLIADTNFD 10 20 30 100 110 120 130 140 150 pF1KB7 VLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASD 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB7 CWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYGPADTMVQYMELFNKIRKQQQVPVAGIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYGPADTMVQYMELFNKIRKQQQVPVAGIR 100 110 120 130 140 150 >>NP_001292386 (OMIM: 612915) mediator of RNA polymerase (123 aa) initn: 767 init1: 767 opt: 767 Z-score: 1023.4 bits: 195.6 E(85289): 2.9e-50 Smith-Waterman score: 767; 99.1% identity (100.0% similar) in 117 aa overlap (1-117:1-117) 10 20 30 40 50 60 pF1KB7 MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 KLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRWSMA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRH NP_001 PVW 212 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:48:50 2016 done: Fri Nov 4 08:48:51 2016 Total Scan time: 5.340 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]