FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7581, 175 aa 1>>>pF1KB7581 175 - 175 aa - 175 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5106+/-0.000537; mu= 13.3840+/- 0.033 mean_var=76.5732+/-15.223, 0's: 0 Z-trim(114.7): 7 B-trim: 16 in 1/51 Lambda= 0.146567 statistics sampled from 15290 (15297) to 15290 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.47), width: 16 Scan time: 1.720 The best scores are: opt bits E(32554) CCDS55651.1 BGLAP gene_id:100527963|Hs108|chr1 ( 175) 1160 253.3 5.8e-68 CCDS55650.1 BGLAP gene_id:100527963|Hs108|chr1 ( 220) 792 175.5 1.8e-44 CCDS30886.1 PMF1 gene_id:11243|Hs108|chr1 ( 205) 791 175.3 2e-44 CCDS60299.1 BGLAP gene_id:100527963|Hs108|chr1 ( 211) 791 175.3 2.1e-44 CCDS55649.1 PMF1 gene_id:11243|Hs108|chr1 ( 180) 790 175.0 2.1e-44 CCDS55648.1 PMF1 gene_id:11243|Hs108|chr1 ( 207) 525 119.0 1.7e-27 CCDS72944.1 BGLAP gene_id:100527963|Hs108|chr1 ( 142) 332 78.1 2.5e-15 >>CCDS55651.1 BGLAP gene_id:100527963|Hs108|chr1 (175 aa) initn: 1160 init1: 1160 opt: 1160 Z-score: 1333.7 bits: 253.3 E(32554): 5.8e-68 Smith-Waterman score: 1160; 99.4% identity (100.0% similar) in 175 aa overlap (1-175:1-175) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PAWCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PAWCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV 130 140 150 160 170 >>CCDS55650.1 BGLAP gene_id:100527963|Hs108|chr1 (220 aa) initn: 797 init1: 776 opt: 792 Z-score: 911.7 bits: 175.5 E(32554): 1.8e-44 Smith-Waterman score: 955; 77.8% identity (78.3% similar) in 207 aa overlap (1-162:1-207) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE 70 80 90 100 110 120 130 pF1KB7 PA-------------------W--------------------------CEAQRCRVQQRC :: : :::::::::::: CCDS55 PACNGTPCGAMCRNRRPRTSSWQMPSWQGGGRWRSCSYRSRPSSRPGRCEAQRCRVQQRC 130 140 150 160 170 180 140 150 160 170 pF1KB7 SLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV ::::::::::::::::::::::::::: CCDS55 SLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV 190 200 210 220 >>CCDS30886.1 PMF1 gene_id:11243|Hs108|chr1 (205 aa) initn: 791 init1: 791 opt: 791 Z-score: 911.0 bits: 175.3 E(32554): 2e-44 Smith-Waterman score: 791; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS30 CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PAWCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV ::: CCDS30 PAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQV 130 140 150 160 170 180 >>CCDS60299.1 BGLAP gene_id:100527963|Hs108|chr1 (211 aa) initn: 791 init1: 791 opt: 791 Z-score: 910.8 bits: 175.3 E(32554): 2.1e-44 Smith-Waterman score: 791; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS60 CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PAWCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV ::: CCDS60 PAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQV 130 140 150 160 170 180 >>CCDS55649.1 PMF1 gene_id:11243|Hs108|chr1 (180 aa) initn: 793 init1: 776 opt: 790 Z-score: 910.7 bits: 175.0 E(32554): 2.1e-44 Smith-Waterman score: 790; 78.4% identity (84.4% similar) in 167 aa overlap (1-159:1-167) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PA--------WCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQE :: :. .: :... :.::. : .. : : : CCDS55 PACNGTPCGAMCRNRRPRTSSWQMPSWQGGGRWRSCSYRSRPSSRPGRLYTENRGSWLLC 130 140 150 160 170 180 pF1KB7 GGV >>CCDS55648.1 PMF1 gene_id:11243|Hs108|chr1 (207 aa) initn: 541 init1: 337 opt: 525 Z-score: 607.0 bits: 119.0 E(32554): 1.7e-27 Smith-Waterman score: 525; 73.8% identity (81.0% similar) in 126 aa overlap (1-123:1-125) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::: . CCDS55 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSSPLLHW 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 CYKCFYQLQPAMTQRIYDKF---IAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKV . .: :. : . . : .: . .:::::::::::::::::::::::::::: CCDS55 DGSAGPRL-PSGGQSVKQAFSWAACRLPQGRKEEISDIKEEGNLEAVLNALDKIVEEGKV 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 RKEPAWCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV :::::: CCDS55 RKEPAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQ 120 130 140 150 160 170 >>CCDS72944.1 BGLAP gene_id:100527963|Hs108|chr1 (142 aa) initn: 332 init1: 332 opt: 332 Z-score: 388.8 bits: 78.1 E(32554): 2.5e-15 Smith-Waterman score: 332; 100.0% identity (100.0% similar) in 53 aa overlap (1-53:1-53) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGRRPSGIP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE CCDS72 EKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQVQAQQQAWQV 70 80 90 100 110 120 175 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:16:20 2016 done: Fri Nov 4 20:16:20 2016 Total Scan time: 1.720 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]