FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7581, 175 aa 1>>>pF1KB7581 175 - 175 aa - 175 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3515+/-0.000244; mu= 14.3568+/- 0.015 mean_var=78.3570+/-15.557, 0's: 0 Z-trim(122.4): 3 B-trim: 66 in 1/54 Lambda= 0.144889 statistics sampled from 40345 (40348) to 40345 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.473), width: 16 Scan time: 4.060 The best scores are: opt bits E(85289) NP_009152 (OMIM: 609176) polyamine-modulated facto ( 205) 791 173.4 1.9e-43 NP_001186582 (OMIM: 609176) polyamine-modulated fa ( 180) 790 173.2 2e-43 NP_001186583 (OMIM: 609176) polyamine-modulated fa ( 207) 525 117.8 1e-26 >>NP_009152 (OMIM: 609176) polyamine-modulated factor 1 (205 aa) initn: 791 init1: 791 opt: 791 Z-score: 901.0 bits: 173.4 E(85289): 1.9e-43 Smith-Waterman score: 791; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: NP_009 CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PAWCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV ::: NP_009 PAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQV 130 140 150 160 170 180 >>NP_001186582 (OMIM: 609176) polyamine-modulated factor (180 aa) initn: 793 init1: 776 opt: 790 Z-score: 900.7 bits: 173.2 E(85289): 2e-43 Smith-Waterman score: 790; 78.4% identity (84.4% similar) in 167 aa overlap (1-159:1-167) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CYKCFYQLQPAMTQRIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: NP_001 CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PA--------WCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQE :: :. .: :... :.::. : .. : : : NP_001 PACNGTPCGAMCRNRRPRTSSWQMPSWQGGGRWRSCSYRSRPSSRPGRLYTENRGSWLLC 130 140 150 160 170 180 pF1KB7 GGV >>NP_001186583 (OMIM: 609176) polyamine-modulated factor (207 aa) initn: 541 init1: 337 opt: 525 Z-score: 600.5 bits: 117.8 E(85289): 1e-26 Smith-Waterman score: 525; 73.8% identity (81.0% similar) in 126 aa overlap (1-123:1-125) 10 20 30 40 50 60 pF1KB7 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::: . NP_001 MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSSPLLHW 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 CYKCFYQLQPAMTQRIYDKF---IAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKV . .: :. : . . : .: . .:::::::::::::::::::::::::::: NP_001 DGSAGPRL-PSGGQSVKQAFSWAACRLPQGRKEEISDIKEEGNLEAVLNALDKIVEEGKV 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 RKEPAWCEAQRCRVQQRCSLCVQAGGQRGSEETQALPVSMAGSPSPLPGSPGAQEGGV :::::: NP_001 RKEPAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQ 120 130 140 150 160 170 175 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:16:21 2016 done: Fri Nov 4 20:16:21 2016 Total Scan time: 4.060 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]