FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7582, 287 aa 1>>>pF1KB7582 287 - 287 aa - 287 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2518+/-0.000331; mu= 7.9605+/- 0.021 mean_var=140.8671+/-28.003, 0's: 0 Z-trim(119.8): 5 B-trim: 311 in 1/54 Lambda= 0.108061 statistics sampled from 34254 (34259) to 34254 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.402), width: 16 Scan time: 7.960 The best scores are: opt bits E(85289) NP_110386 (OMIM: 616477) nuclear receptor-binding ( 287) 1879 303.8 2.5e-82 NP_001269334 (OMIM: 616477) nuclear receptor-bindi ( 277) 1631 265.1 1.1e-70 XP_006717873 (OMIM: 616477) PREDICTED: nuclear rec ( 243) 1597 259.8 3.8e-69 NP_001244210 (OMIM: 267000,614184) DIS3-like exonu ( 603) 251 50.2 1.1e-05 >>NP_110386 (OMIM: 616477) nuclear receptor-binding fact (287 aa) initn: 1879 init1: 1879 opt: 1879 Z-score: 1599.0 bits: 303.8 E(85289): 2.5e-82 Smith-Waterman score: 1879; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KB7 MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMKLTQSEQAHLSLELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMKLTQSEQAHLSLELQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RDSHMKQLLLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLSQKYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 RDSHMKQLLLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLSQKYS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PSTEKCLPEIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 PSTEKCLPEIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HVEFLVAENERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 HVEFLVAENERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATAS 190 200 210 220 230 240 250 260 270 280 pF1KB7 STWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN ::::::::::::::::::::::::::::::::::::::::::::::: NP_110 STWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN 250 260 270 280 >>NP_001269334 (OMIM: 616477) nuclear receptor-binding f (277 aa) initn: 1631 init1: 1631 opt: 1631 Z-score: 1390.2 bits: 265.1 E(85289): 1.1e-70 Smith-Waterman score: 1631; 100.0% identity (100.0% similar) in 249 aa overlap (39-287:29-277) 10 20 30 40 50 60 pF1KB7 NLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMKLTQSEQAHLSLELQRDSHMKQL :::::::::::::::::::::::::::::: NP_001 MFPGATTPLPKAAAYPGVYGSNGRTPQPAYLSEAMKLTQSEQAHLSLELQRDSHMKQL 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 LLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLSQKYSPSTEKCLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLSQKYSPSTEKCLP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 EIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 NERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAA 180 190 200 210 220 230 250 260 270 280 pF1KB7 NTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN ::::::::::::::::::::::::::::::::::::::: NP_001 NTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN 240 250 260 270 >>XP_006717873 (OMIM: 616477) PREDICTED: nuclear recepto (243 aa) initn: 1597 init1: 1597 opt: 1597 Z-score: 1362.4 bits: 259.8 E(85289): 3.8e-69 Smith-Waterman score: 1597; 100.0% identity (100.0% similar) in 243 aa overlap (45-287:1-243) 20 30 40 50 60 70 pF1KB7 SRRADRLLAAGKYEEAISCHKKAAAYLSEAMKLTQSEQAHLSLELQRDSHMKQLLLIQER :::::::::::::::::::::::::::::: XP_006 MKLTQSEQAHLSLELQRDSHMKQLLLIQER 10 20 30 80 90 100 110 120 130 pF1KB7 WKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLSQKYSPSTEKCLPEIQGIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLSQKYSPSTEKCLPEIQGIF 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB7 DRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRK 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB7 ENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAANTGKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAANTGKAK 160 170 180 190 200 210 260 270 280 pF1KB7 DIPIPNLPPLDFPSPELPLMELSEDILKGFMNN ::::::::::::::::::::::::::::::::: XP_006 DIPIPNLPPLDFPSPELPLMELSEDILKGFMNN 220 230 240 >>NP_001244210 (OMIM: 267000,614184) DIS3-like exonuclea (603 aa) initn: 287 init1: 143 opt: 251 Z-score: 222.8 bits: 50.2 E(85289): 1.1e-05 Smith-Waterman score: 261; 54.4% identity (73.3% similar) in 90 aa overlap (87-175:527-601) 60 70 80 90 100 110 pF1KB7 LELQRDSHMKQLLLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLS :::.:::.:::::.::.:::::::.: NP_001 AQSMIESPTEKIPAKELPPISPEHSSEEVHQQNADKDGAAHLQASHSPSAEDAEAQ---- 500 510 520 530 540 550 120 130 140 150 160 170 pF1KB7 QKYSPSTEKCLPEIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTI-IEEQATKI ::::. ::: .:: :::::: :..:::.:. : : ..:: .:::.:.. NP_001 ----PSTEERLPETRGICDRDPDTRLFFLQQQSRVLEA-------KPQNTIRVEEQTTQL 560 570 580 590 600 180 190 200 210 220 230 pF1KB7 ADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAE NP_001 QI 287 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 15:29:24 2016 done: Sun Nov 6 15:29:25 2016 Total Scan time: 7.960 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]