FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7584, 287 aa
1>>>pF1KB7584 287 - 287 aa - 287 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9516+/-0.000827; mu= 1.5380+/- 0.050
mean_var=251.8123+/-52.170, 0's: 0 Z-trim(116.2): 169 B-trim: 0 in 0/53
Lambda= 0.080823
statistics sampled from 16660 (16836) to 16660 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.517), width: 16
Scan time: 2.500
The best scores are: opt bits E(32554)
CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 ( 287) 1983 243.3 1.6e-64
CCDS5647.1 DLX5 gene_id:1749|Hs108|chr7 ( 289) 888 115.6 4.4e-26
CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 ( 328) 735 97.8 1.1e-20
CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 ( 293) 473 67.2 1.6e-11
CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 ( 255) 466 66.3 2.6e-11
>>CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 (287 aa)
initn: 1983 init1: 1983 opt: 1983 Z-score: 1271.9 bits: 243.3 E(32554): 1.6e-64
Smith-Waterman score: 1983; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287)
10 20 30 40 50 60
pF1KB7 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS
190 200 210 220 230 240
250 260 270 280
pF1KB7 PSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY
250 260 270 280
>>CCDS5647.1 DLX5 gene_id:1749|Hs108|chr7 (289 aa)
initn: 816 init1: 629 opt: 888 Z-score: 581.8 bits: 115.6 E(32554): 4.4e-26
Smith-Waterman score: 888; 53.8% identity (73.6% similar) in 288 aa overlap (1-274:1-279)
10 20 30 40 50
pF1KB7 MSGSFDRKLSSILTD-----ISSSLSCHAGSKDSPTLPESSVTDLGYYS----APQHDYY
:.: :::.. :: . ...: . : :..::::::::.:: ::: :: : :
CCDS56 MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAP-HGYC
10 20 30 40 50
60 70 80 90 100
pF1KB7 S--GQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYG-AYREQPLPAQDP
: . ::...::: :... ..:: ::. . ..:.:..::.::: :: . : ...:
CCDS56 SPTSASYGKALNPYQYQYH-GVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 VSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGL
:: : :::::::::::::::::::::.:::::::::::.:::::::::::::.:::
CCDS56 --EKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 TQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPAR
:::::::::::.:::.::..::::.: ::::..:: :::::: :::.:. .. : .
CCDS56 TQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 SQLPPPLP-YSASPSYLDDPTNSWYHAQNLS-GPHLQQQPPQPATLHHASPGPPPNPGAV
. :: : . :::.. . ::: . : . :: :: :..:.:
CCDS56 PHAHPPTSNQSPASSYLEN-SASWYTSAASSINSHL---PP-PGSLQHPLALASGTLY
240 250 260 270 280
pF1KB7 Y
>>CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 (328 aa)
initn: 700 init1: 532 opt: 735 Z-score: 484.7 bits: 97.8 E(32554): 1.1e-20
Smith-Waterman score: 754; 47.8% identity (65.4% similar) in 295 aa overlap (17-287:42-328)
10 20 30 40
pF1KB7 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAP
::: : : ..::::: :..:: .::.
CCDS22 MHSTQIAASSTYHQHQQPPSGGGAGPGGNSSSSSSLHK-PQESPTLPVSTATDSSYYTNQ
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB7 QHDYYSGQPYGQTVNPYTYH--HQFNLNGLAGTGAYSPKSEYTYG--ASYRQYGAYREQP
:: .: : .::.. .:.. .:: .. :: :: : : :.: .:. : .
CCDS22 QHPAGGGGGGG---SPYAHMGSYQYQASGLNNV-PYSAKSSYDLGYTAAYTSYAPYGTSS
80 90 100 110 120
110 120 130 140 150 160
pF1KB7 LPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAEL
::.. ::. : :.:.:::::::::::::::::.:::::::::::.:::::::::::
CCDS22 SPANNEPE-KEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAEL
130 140 150 160 170 180
170 180 190 200 210
pF1KB7 AAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPP--SPALWD---
::.:::::::::::::::::::::..:.::.: :. :. : : : ::: .:: ::
CCDS22 AASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCASPPVSAPASWDFGV
190 200 210 220 230 240
220 230 240 250 260
pF1KB7 ---TSSHSTPAPARSQLPPP--LPYSASPSYLDDPTNSWYHAQNLSGPHLQQ--------
.. . :. . : : ::. ..: . ::: . :. :::
CCDS22 PQRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGN--YPWYHQTSGSASHLQATAPLLHPT
250 260 270 280 290 300
270 280
pF1KB7 QPPQPATLHH--ASPGPPPNPGAVY
: ::: :: .. : : . :...
CCDS22 QTPQPHHHHHHHGGGGAPVSAGTIF
310 320
>>CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 (293 aa)
initn: 423 init1: 388 opt: 473 Z-score: 320.2 bits: 67.2 E(32554): 1.6e-11
Smith-Waterman score: 483; 41.1% identity (64.0% similar) in 258 aa overlap (30-268:52-291)
10 20 30 40 50
pF1KB7 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSA--PQHDYYSGQPYG
: :.:. .. .. .: : : .:. .
CCDS47 MEFGQQQQQQQQQQQQQQQQQQQPPPPPPPPPQPHSQQSSPAMAGAHYPLHCLHSAAAAA
30 40 50 60 70 80
60 70 80 90 100
pF1KB7 QTVNPYTYHHQFNLNG---LAGTG-AYSPKSEYTYG-ASYRQYG----AYREQPLPAQ--
. . . .::: . .: .: : .:. .: .: :. :.. .:... ::
CCDS47 AAGSHHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQSYHNSSAAAQTR
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB7 -DPVSVKEEP---EAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAEL
: .. .. ..:.:. ::: ::.::::::::: :: ::..:::..:::::::::::
CCDS47 GDDTDQQKTTVIENGEIRF-NGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAEL
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB7 AAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNSPPSPALWDTSSH
::.::::::::::::::.::::::: :.: : : .: ..: ... :: : .::.:
CCDS47 AASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALPPVWDVS--
210 220 230 240 250
230 240 250 260 270 280
pF1KB7 STPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQ-QQPPQPATLHHASPGPP
: :.. :: : :.: . :: :.:: . .: ::
CCDS47 ---ASAKGVSMPPNSYM--PGY-----SHWY-----SSPHQDTMQRPQMM
260 270 280 290
pF1KB7 PNPGAVY
>>CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 (255 aa)
initn: 457 init1: 388 opt: 466 Z-score: 316.6 bits: 66.3 E(32554): 2.6e-11
Smith-Waterman score: 477; 41.0% identity (60.5% similar) in 266 aa overlap (3-262:24-254)
10 20 30
pF1KB7 MSGSFDRKLS-SILTDISSSLSC-HAGSKDSPTLPESSV
: ....: : .. :. : :......:
CCDS22 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQP-------
10 20 30 40 50
40 50 60 70 80 90
pF1KB7 TDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGA
: .: :: . . : :: :: . : :.. : . : .:: : .
CCDS22 -DGAYSSASSFSRPLGYPY---VNSVSSH--------ASSPYISSVQSYPGSASLAQ--S
60 70 80 90
100 110 120 130 140 150
pF1KB7 YREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALP
:.: .. .: : .:::. ::: ::.::::::::: :: ::.::::..::::::
CCDS22 RLEDPGADSEKSTVVEG--GEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALP
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB7 ERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNSPPSPALW
:::::::.::::::::::::::.:::::::.:.: . :: : :. ... .::: : :
CCDS22 ERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGW
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB7 DTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWY---HAQNLSGPHLQQQPPQPATLH
. .: : . . . : ::: .::: : . .. :.:
CCDS22 NPNSSSGKGSGGNA------GSYIPSY-----TSWYPSAHQEAMQQPQLM
220 230 240 250
280
pF1KB7 HASPGPPPNPGAVY
287 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:17:03 2016 done: Fri Nov 4 20:17:03 2016
Total Scan time: 2.500 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]