FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7584, 287 aa 1>>>pF1KB7584 287 - 287 aa - 287 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9516+/-0.000827; mu= 1.5380+/- 0.050 mean_var=251.8123+/-52.170, 0's: 0 Z-trim(116.2): 169 B-trim: 0 in 0/53 Lambda= 0.080823 statistics sampled from 16660 (16836) to 16660 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.517), width: 16 Scan time: 2.500 The best scores are: opt bits E(32554) CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 ( 287) 1983 243.3 1.6e-64 CCDS5647.1 DLX5 gene_id:1749|Hs108|chr7 ( 289) 888 115.6 4.4e-26 CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 ( 328) 735 97.8 1.1e-20 CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 ( 293) 473 67.2 1.6e-11 CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 ( 255) 466 66.3 2.6e-11 >>CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 (287 aa) initn: 1983 init1: 1983 opt: 1983 Z-score: 1271.9 bits: 243.3 E(32554): 1.6e-64 Smith-Waterman score: 1983; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KB7 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSAS 190 200 210 220 230 240 250 260 270 280 pF1KB7 PSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY ::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY 250 260 270 280 >>CCDS5647.1 DLX5 gene_id:1749|Hs108|chr7 (289 aa) initn: 816 init1: 629 opt: 888 Z-score: 581.8 bits: 115.6 E(32554): 4.4e-26 Smith-Waterman score: 888; 53.8% identity (73.6% similar) in 288 aa overlap (1-274:1-279) 10 20 30 40 50 pF1KB7 MSGSFDRKLSSILTD-----ISSSLSCHAGSKDSPTLPESSVTDLGYYS----APQHDYY :.: :::.. :: . ...: . : :..::::::::.:: ::: :: : : CCDS56 MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAP-HGYC 10 20 30 40 50 60 70 80 90 100 pF1KB7 S--GQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYG-AYREQPLPAQDP : . ::...::: :... ..:: ::. . ..:.:..::.::: :: . : ...: CCDS56 SPTSASYGKALNPYQYQYH-GVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQP 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 VSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGL :: : :::::::::::::::::::::.:::::::::::.:::::::::::::.::: CCDS56 --EKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 TQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPAR :::::::::::.:::.::..::::.: ::::..:: :::::: :::.:. .. : . CCDS56 TQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHH 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 SQLPPPLP-YSASPSYLDDPTNSWYHAQNLS-GPHLQQQPPQPATLHHASPGPPPNPGAV . :: : . :::.. . ::: . : . :: :: :..:.: CCDS56 PHAHPPTSNQSPASSYLEN-SASWYTSAASSINSHL---PP-PGSLQHPLALASGTLY 240 250 260 270 280 pF1KB7 Y >>CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 (328 aa) initn: 700 init1: 532 opt: 735 Z-score: 484.7 bits: 97.8 E(32554): 1.1e-20 Smith-Waterman score: 754; 47.8% identity (65.4% similar) in 295 aa overlap (17-287:42-328) 10 20 30 40 pF1KB7 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAP ::: : : ..::::: :..:: .::. CCDS22 MHSTQIAASSTYHQHQQPPSGGGAGPGGNSSSSSSLHK-PQESPTLPVSTATDSSYYTNQ 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB7 QHDYYSGQPYGQTVNPYTYH--HQFNLNGLAGTGAYSPKSEYTYG--ASYRQYGAYREQP :: .: : .::.. .:.. .:: .. :: :: : : :.: .:. : . CCDS22 QHPAGGGGGGG---SPYAHMGSYQYQASGLNNV-PYSAKSSYDLGYTAAYTSYAPYGTSS 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 LPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAEL ::.. ::. : :.:.:::::::::::::::::.:::::::::::.::::::::::: CCDS22 SPANNEPE-KEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAEL 130 140 150 160 170 180 170 180 190 200 210 pF1KB7 AAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPP--SPALWD--- ::.:::::::::::::::::::::..:.::.: :. :. : : : ::: .:: :: CCDS22 AASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCASPPVSAPASWDFGV 190 200 210 220 230 240 220 230 240 250 260 pF1KB7 ---TSSHSTPAPARSQLPPP--LPYSASPSYLDDPTNSWYHAQNLSGPHLQQ-------- .. . :. . : : ::. ..: . ::: . :. ::: CCDS22 PQRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGN--YPWYHQTSGSASHLQATAPLLHPT 250 260 270 280 290 300 270 280 pF1KB7 QPPQPATLHH--ASPGPPPNPGAVY : ::: :: .. : : . :... CCDS22 QTPQPHHHHHHHGGGGAPVSAGTIF 310 320 >>CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 (293 aa) initn: 423 init1: 388 opt: 473 Z-score: 320.2 bits: 67.2 E(32554): 1.6e-11 Smith-Waterman score: 483; 41.1% identity (64.0% similar) in 258 aa overlap (30-268:52-291) 10 20 30 40 50 pF1KB7 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSA--PQHDYYSGQPYG : :.:. .. .. .: : : .:. . CCDS47 MEFGQQQQQQQQQQQQQQQQQQQPPPPPPPPPQPHSQQSSPAMAGAHYPLHCLHSAAAAA 30 40 50 60 70 80 60 70 80 90 100 pF1KB7 QTVNPYTYHHQFNLNG---LAGTG-AYSPKSEYTYG-ASYRQYG----AYREQPLPAQ-- . . . .::: . .: .: : .:. .: .: :. :.. .:... :: CCDS47 AAGSHHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQSYHNSSAAAQTR 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 -DPVSVKEEP---EAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAEL : .. .. ..:.:. ::: ::.::::::::: :: ::..:::..::::::::::: CCDS47 GDDTDQQKTTVIENGEIRF-NGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAEL 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB7 AAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNSPPSPALWDTSSH ::.::::::::::::::.::::::: :.: : : .: ..: ... :: : .::.: CCDS47 AASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALPPVWDVS-- 210 220 230 240 250 230 240 250 260 270 280 pF1KB7 STPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQ-QQPPQPATLHHASPGPP : :.. :: : :.: . :: :.:: . .: :: CCDS47 ---ASAKGVSMPPNSYM--PGY-----SHWY-----SSPHQDTMQRPQMM 260 270 280 290 pF1KB7 PNPGAVY >>CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 (255 aa) initn: 457 init1: 388 opt: 466 Z-score: 316.6 bits: 66.3 E(32554): 2.6e-11 Smith-Waterman score: 477; 41.0% identity (60.5% similar) in 266 aa overlap (3-262:24-254) 10 20 30 pF1KB7 MSGSFDRKLS-SILTDISSSLSC-HAGSKDSPTLPESSV : ....: : .. :. : :......: CCDS22 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQP------- 10 20 30 40 50 40 50 60 70 80 90 pF1KB7 TDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGA : .: :: . . : :: :: . : :.. : . : .:: : . CCDS22 -DGAYSSASSFSRPLGYPY---VNSVSSH--------ASSPYISSVQSYPGSASLAQ--S 60 70 80 90 100 110 120 130 140 150 pF1KB7 YREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALP :.: .. .: : .:::. ::: ::.::::::::: :: ::.::::..:::::: CCDS22 RLEDPGADSEKSTVVEG--GEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALP 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB7 ERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNSPPSPALW :::::::.::::::::::::::.:::::::.:.: . :: : :. ... .::: : : CCDS22 ERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGW 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB7 DTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWY---HAQNLSGPHLQQQPPQPATLH . .: : . . . : ::: .::: : . .. :.: CCDS22 NPNSSSGKGSGGNA------GSYIPSY-----TSWYPSAHQEAMQQPQLM 220 230 240 250 280 pF1KB7 HASPGPPPNPGAVY 287 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:17:03 2016 done: Fri Nov 4 20:17:03 2016 Total Scan time: 2.500 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]