FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7587, 224 aa
  1>>>pF1KB7587 224 - 224 aa - 224 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7024+/-0.000263; mu= 14.6219+/- 0.017
 mean_var=104.0911+/-21.787, 0's: 0 Z-trim(122.7): 50  B-trim: 2111 in 1/54
 Lambda= 0.125709
 statistics sampled from 41280 (41342) to 41280 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.485), width:  16
 Scan time:  5.700

The best scores are:                                      opt bits E(85289)
NP_002470 (OMIM: 159980) myogenin [Homo sapiens]   ( 224) 1536 287.8 9.8e-78
NP_002460 (OMIM: 159991,614408) myogenic factor 6  ( 242)  527 104.9 1.3e-22
NP_005584 (OMIM: 159990) myogenic factor 5 [Homo s ( 255)  471 94.7 1.5e-19
NP_002469 (OMIM: 159970) myoblast determination pr ( 320)  422 85.9 8.3e-17
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328)  167 39.7  0.0071


>>NP_002470 (OMIM: 159980) myogenin [Homo sapiens]        (224 aa)
 initn: 1536 init1: 1536 opt: 1536  Z-score: 1516.6  bits: 287.8 E(85289): 9.8e-78
Smith-Waterman score: 1536; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)

               10        20        30        40        50        60
pF1KB7 MELYETSPYFYQEPRFYDGENYLPVHLQGFEPPGYERTELTLSPEAPGPLEDKGLGTPEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MELYETSPYFYQEPRFYDGENYLPVHLQGFEPPGYERTELTLSPEAPGPLEDKGLGTPEH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVPSECSSHSASCSPEWGSALEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVPSECSSHSASCSPEWGSALEFS
              130       140       150       160       170       180

              190       200       210       220    
pF1KB7 ANPGDHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETMPN
       ::::::::::::::::::::::::::::::::::::::::::::
NP_002 ANPGDHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETMPN
              190       200       210       220    

>>NP_002460 (OMIM: 159991,614408) myogenic factor 6 [Hom  (242 aa)
 initn: 542 init1: 463 opt: 527  Z-score: 527.2  bits: 104.9 E(85289): 1.3e-22
Smith-Waterman score: 570; 45.6% identity (64.0% similar) in 250 aa overlap (1-222:3-240)

                 10        20        30            40              
pF1KB7   MELYETSPYFYQEPRFYDGENYLPVHLQGFE----PPGYERTELTLSP----------
         :.:.::. ::.    . ::::   : :: .:     : :  .. ::::          
NP_002 MMMDLFETGSYFF----YLDGEN---VTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAG
               10               20        30        40        50   

               50        60        70        80        90       100
pF1KB7 -EAPGP---LEDKGLGTPEHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEA
        .. :    :   ::  : ::::::: ::::.:::::. .:::.::::::.:::::.:::
NP_002 SDSSGEEHVLAPPGL-QPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEA
            60         70        80        90       100       110  

              110       120       130       140       150       160
pF1KB7 FEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVPS
       :::::: :. ::::::::::::::::.:::::: ::  :.:.:.  .   :  :    :.
NP_002 FEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQEL--GVDPFSYRPK
            120       130       140       150       160         170

                  170             180       190       200       210
pF1KB7 ECSSHSA----SCSPEWGSA------LEFSANPGDHLLTADPTDAHNLHSLTSIVDSITV
       . . ..:    .:: .: :.      : ..:. :    . : . . .:. :.::::::. 
NP_002 QENLEGADFLRTCSSQWPSVSDHSRGLVITAKEGG--ASIDSSASSSLRCLSSIVDSISS
              180       190       200         210       220        

              220    
pF1KB7 EDVSVAFPDETMPN
       :. ..   .:..  
NP_002 EERKLPCVEEVVEK
      230       240  

>>NP_005584 (OMIM: 159990) myogenic factor 5 [Homo sapie  (255 aa)
 initn: 461 init1: 393 opt: 471  Z-score: 472.0  bits: 94.7 E(85289): 1.5e-19
Smith-Waterman score: 471; 42.9% identity (64.8% similar) in 219 aa overlap (4-209:9-215)

                    10             20        30        40        50
pF1KB7      MELYETSPYFYQ-----EPRFYDGENYLPVHLQGFEPPGYERTELTLSPEAPGPL
               .  : :::.      :.   :....: .. .:   : ...::       :  
NP_005 MDVMDGCQFSPSEYFYDGSCIPSPEGEFGDEFVP-RVAAF---GAHKAELQ------GSD
               10        20        30            40              50

                 60        70        80        90       100        
pF1KB7 EDKGLGTP--EHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRST
       ::. . .:  .:  :.:: ::::.:::::...:::.:::.::.:::::::.:::.::: :
NP_005 EDEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCT
               60        70        80        90       100       110

      110       120       130       140       150        160       
pF1KB7 LLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVP-SECSSHSA
         :::::::::::::.::.::: :: ::   .: :      : .  .:  : :.::.   
NP_005 TTNPNQRLPKVEILRNAIRYIESLQELLR--EQVENYYSLPGQSCSEPTSPTSNCSDGMP
              120       130         140       150       160        

        170          180        190       200       210       220  
pF1KB7 SC-SPEWG---SALEFSANPG-DHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETM
        : :: :.   :...    :  ... ..: ..  .:  :..::: ::             
NP_005 ECNSPVWSRKSSTFDSIYCPDVSNVYATDKNSLSSLDCLSNIVDRITSSEQPGLPLQDLA
      170       180       190       200       210       220        

                                  
pF1KB7 PN                         
                                  
NP_005 SLSPVASTDSQPATPGASSSRLIYHVL
      230       240       250     

>>NP_002469 (OMIM: 159970) myoblast determination protei  (320 aa)
 initn: 444 init1: 382 opt: 422  Z-score: 422.7  bits: 85.9 E(85289): 8.3e-17
Smith-Waterman score: 434; 41.7% identity (64.3% similar) in 199 aa overlap (4-183:23-217)

                                  10               20        30    
pF1KB7                    MELYETSPYFYQEP-------RFYDGENYLPVHLQGF-EPP
                             . :.  ::..:       ::..  .   .:. .. .: 
NP_002 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE
               10        20        30        40        50        60

            40        50          60        70        80        90 
pF1KB7 GYERTELTLSPEAPGPLEDKGLGTP--EHCPGQCLPWACKVCKRKSVSVDRRRAATLREK
        . .   .. : :::  ::. . .:  .:  :.:: ::::.::::....:::.:::.::.
NP_002 EHSHFPAAVHP-APGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRER
               70         80        90       100       110         

             100       110       120       130       140           
pF1KB7 RRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLR---Y
       :::.:::::::.::: :  :::::::::::::.::.::: ::::: . .          :
NP_002 RRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFY
     120       130       140       150       160       170         

      150             160       170       180       190       200  
pF1KB7 RGG------GGPQPGVPSECSSHSASCSPEWGSALEFSANPGDHLLTADPTDAHNLHSLT
         :      :: . .  :. ::  ..::    . ...:. :                   
NP_002 APGPLPPGRGGEHYSGDSDASSPRSNCSD---GMMDYSGPPSGARRRNCYEGAYYNEAPS
     180       190       200          210       220       230      

            210       220                                          
pF1KB7 SIVDSITVEDVSVAFPDETMPN                                      
                                                                   
NP_002 EPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGD
        240       250       260       270       280       290      

>>NP_835455 (OMIM: 607194,609069,615935) pancreas transc  (328 aa)
 initn: 145 init1:  95 opt: 167  Z-score: 172.6  bits: 39.7 E(85289): 0.0071
Smith-Waterman score: 167; 44.9% identity (66.7% similar) in 78 aa overlap (83-159:165-236)

             60        70        80        90       100       110  
pF1KB7 KGLGTPEHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNP
                                     :.::..::.::....:.:::.:.      :
NP_835 GARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLP
          140       150       160       170       180       190    

             120       130       140       150       160       170 
pF1KB7 -NQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVPSECSSHSASCSP
        ..:: ::. :: :: ::.    .:: : :   ::  ::::.   : :            
NP_835 YEKRLSKVDTLRLAIGYIN----FLSELVQA--DLPLRGGGAGGCGGPGGGGRLGGDSPG
          200       210           220         230       240        

             180       190       200       210       220           
pF1KB7 EWGSALEFSANPGDHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETMPN       
                                                                   
NP_835 SQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKVWTPEDPRK
      250       260       270       280       290       300        




224 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 08:52:22 2016 done: Fri Nov  4 08:52:23 2016
 Total Scan time:  5.700 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]