FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7588, 289 aa 1>>>pF1KB7588 289 - 289 aa - 289 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5075+/-0.000848; mu= 2.2072+/- 0.052 mean_var=193.7614+/-40.628, 0's: 0 Z-trim(114.2): 175 B-trim: 782 in 1/50 Lambda= 0.092138 statistics sampled from 14609 (14797) to 14609 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.455), width: 16 Scan time: 2.880 The best scores are: opt bits E(32554) CCDS5647.1 DLX5 gene_id:1749|Hs108|chr7 ( 289) 1970 273.5 1.3e-73 CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 ( 287) 888 129.7 2.5e-30 CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 ( 328) 783 115.7 4.4e-26 CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 ( 293) 517 80.3 1.8e-15 CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 ( 255) 476 74.9 7e-14 >>CCDS5647.1 DLX5 gene_id:1749|Hs108|chr7 (289 aa) initn: 1970 init1: 1970 opt: 1970 Z-score: 1435.2 bits: 273.5 E(32554): 1.3e-73 Smith-Waterman score: 1970; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289) 10 20 30 40 50 60 pF1KB7 MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PTSASYGKALNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PTSASYGKALNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQPEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 VKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAH 190 200 210 220 230 240 250 260 270 280 pF1KB7 PPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASGTLY ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASGTLY 250 260 270 280 >>CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 (287 aa) initn: 816 init1: 629 opt: 888 Z-score: 657.9 bits: 129.7 E(32554): 2.5e-30 Smith-Waterman score: 888; 53.8% identity (73.6% similar) in 288 aa overlap (1-279:1-274) 10 20 30 40 50 pF1KB7 MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAP-HGYC :.: :::.. :: . ...: . : :..::::::::.:: ::: :: : : CCDS11 MSGSFDRKLSSILTD-----ISSSLSCHAGSKDSPTLPESSVTDLGYYS----APQHDYY 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 SPTSASYGKALNPYQYQYH-GVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQP : . ::...::: :... ..:: ::. . ..:.:..::.::: :: . : ...: CCDS11 S--GQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYG-AYREQPLPAQDP 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 E--KEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGL :: : :::::::::::::::::::::.:::::::::::.:::::::::::::.::: CCDS11 VSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 TQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHH :::::::::::.:::.::..::::.: ::::..:: :::::: :::.:. .. : . CCDS11 TQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPAR 170 180 190 200 210 220 240 250 260 270 280 pF1KB7 PHAHPPTSNQSPASSYLEN-SASWYTSAASSINSHL---PP-PGSLQHPLALASGTLY . :: : . :::.. . ::: . : . :: :: :..:.: CCDS11 SQLPPPLP-YSASPSYLDDPTNSWYHAQNLS-GPHLQQQPPQPATLHHASPGPPPNPGAV 230 240 250 260 270 280 CCDS11 Y >>CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 (328 aa) initn: 713 init1: 600 opt: 783 Z-score: 581.7 bits: 115.7 E(32554): 4.4e-26 Smith-Waterman score: 783; 52.2% identity (71.1% similar) in 270 aa overlap (23-280:43-302) 10 20 30 40 pF1KB7 MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYS--- .:...:.: ::::::: :.::::.::. CCDS22 HSTQIAASSTYHQHQQPPSGGGAGPGGNSSSSSSLHKP-QESPTLPVSTATDSSYYTNQQ 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB7 -PTGGAPHGYCSPTSASYGKALNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAY :.::. : :: :.. .. :::: :.:. : ::. : .:...: .:. CCDS22 HPAGGGGGGG-SP----YAH-MGSYQYQASGLNNVP--YSAKSSYDLGYTAAYTSYAPYG 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 NRVPSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERA . :.:.:::: :::.:.::::::::::::::::::::::::::::::::::::::: CCDS22 TSSSPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 ELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSP--QSPAVWE- :::::::::::::::::::.:::.::. :.::.: :. :..: : :: ..:: :. CCDS22 ELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCASPPVSAPASWDF 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 --PQ---GSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHP :: :.. : : :. : :.: . .. :: ....: ::: . : :: CCDS22 GVPQRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGNYPWYHQTSGSA-SHLQATAPLLHP 250 260 270 280 290 300 pF1KB7 LALASGTLY CCDS22 TQTPQPHHHHHHHGGGGAPVSAGTIF 310 320 >>CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 (293 aa) initn: 537 init1: 427 opt: 517 Z-score: 391.3 bits: 80.3 E(32554): 1.8e-15 Smith-Waterman score: 545; 40.8% identity (63.8% similar) in 265 aa overlap (18-262:30-281) 10 20 30 40 pF1KB7 MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYY : : . ... .: : : :. CCDS47 MMTMTTMADGLEGQDSSKSAFMEFGQQQQQQQQQQQQQQQQQQQPPPPPPPPPQPHSQQS 10 20 30 40 50 60 50 60 70 80 90 pF1KB7 SPTGGAPHG--YCSPTSASYGKA----LNPYQYQYHG---VNGSAGSYPAKAYADYSYAS ::. .. : .: ..:. . : . .:...:: ..:...:: .. : : : : CCDS47 SPAMAGAHYPLHCLHSAAAAAAAGSHHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYMS 70 80 90 100 110 120 100 110 120 130 140 pF1KB7 ---------SYHQYGGAYNRVPSATNQPEKEVTEP-EVRMVNGKPKKVRKPRTIYSSFQL :::. ..: . . :.: . : : :.:. ::: ::.:::::::::.:: CCDS47 HSQHSPYLQSYHNSSAAAQTRGDDTDQQKTTVIENGEIRF-NGKGKKIRKPRTIYSSLQL 130 140 150 160 170 150 160 170 180 190 200 pF1KB7 AALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSP-S ::..:::.:::::::::::::::::::::::::::::::::.::..:.: : : .: . CCDS47 QALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQ 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 SSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSIN .: .. :: : ::. ..:....: :: .::. . . ::.: CCDS47 GSAALSPRSPALPPVWDVSASAKGVSM-----PP-------NSYMPGYSHWYSSPHQDTM 240 250 260 270 280 270 280 pF1KB7 SHLPPPGSLQHPLALASGTLY CCDS47 QRPQMM 290 >>CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 (255 aa) initn: 430 init1: 389 opt: 476 Z-score: 362.7 bits: 74.9 E(32554): 7e-14 Smith-Waterman score: 501; 43.7% identity (63.5% similar) in 252 aa overlap (36-263:5-244) 10 20 30 40 50 60 pF1KB7 DRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPES--SATDSDYYSPTGGAPHGYCSPTS :.::: : ... : :. ::. CCDS22 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSP 10 20 30 70 80 90 100 pF1KB7 ASYGK-ALNPYQYQYH----GVNGSAGS------YP----AKAYADYSYASSYHQYGG-- :.:. ... . : :. .::.: :: ....:. : :: ..: : CCDS22 MSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSA 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB7 --AYNRV--PSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYL : .:. :.: .. : :::. ::: ::.:::::::::.:: ::.::::.:::: CCDS22 SLAQSRLEDPGADSEKSTVVEGGEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYL 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB7 ALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSP-SSSDPMACNSPQSP :::::::::::::::::::::::::::::.::.::.: : : ... .. .:: : CCDS22 ALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVP 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB7 AVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPL :.:..:: . : . :.::. . .::: :: CCDS22 PGWNPNSSSGKGSG-----------GNAGSYIPSYTSWYPSAHQEAMQQPQLM 220 230 240 250 pF1KB7 ALASGTLY 289 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:53:13 2016 done: Fri Nov 4 08:53:13 2016 Total Scan time: 2.880 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]