FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7600, 434 aa 1>>>pF1KB7600 434 - 434 aa - 434 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2056+/-0.00105; mu= 9.0082+/- 0.063 mean_var=125.5730+/-24.576, 0's: 0 Z-trim(107.6): 26 B-trim: 7 in 1/50 Lambda= 0.114453 statistics sampled from 9664 (9682) to 9664 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.297), width: 16 Scan time: 3.250 The best scores are: opt bits E(32554) CCDS12137.1 PLIN3 gene_id:10226|Hs108|chr19 ( 434) 2740 463.8 1.5e-130 CCDS59338.1 PLIN3 gene_id:10226|Hs108|chr19 ( 433) 2721 460.7 1.3e-129 CCDS59337.1 PLIN3 gene_id:10226|Hs108|chr19 ( 422) 1953 333.9 1.9e-91 CCDS6490.1 PLIN2 gene_id:123|Hs108|chr9 ( 437) 1170 204.6 1.6e-52 CCDS42473.1 PLIN5 gene_id:440503|Hs108|chr19 ( 463) 699 126.8 4.3e-29 CCDS10353.1 PLIN1 gene_id:5346|Hs108|chr15 ( 522) 389 75.7 1.2e-13 >>CCDS12137.1 PLIN3 gene_id:10226|Hs108|chr19 (434 aa) initn: 2740 init1: 2740 opt: 2740 Z-score: 2457.5 bits: 463.8 E(32554): 1.5e-130 Smith-Waterman score: 2740; 99.8% identity (100.0% similar) in 434 aa overlap (1-434:1-434) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: CCDS12 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 370 380 390 400 410 420 430 pF1KB7 FAPGITEKAPEEKK :::::::::::::: CCDS12 FAPGITEKAPEEKK 430 >>CCDS59338.1 PLIN3 gene_id:10226|Hs108|chr19 (433 aa) initn: 2015 init1: 2015 opt: 2721 Z-score: 2440.6 bits: 460.7 E(32554): 1.3e-129 Smith-Waterman score: 2721; 99.5% identity (99.8% similar) in 434 aa overlap (1-434:1-433) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: CCDS59 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: CCDS59 WLSWNQKQLQGPEKEPPKPE-VESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 360 370 380 390 400 410 430 pF1KB7 FAPGITEKAPEEKK :::::::::::::: CCDS59 FAPGITEKAPEEKK 420 430 >>CCDS59337.1 PLIN3 gene_id:10226|Hs108|chr19 (422 aa) initn: 1949 init1: 1949 opt: 1953 Z-score: 1755.4 bits: 333.9 E(32554): 1.9e-91 Smith-Waterman score: 2640; 97.0% identity (97.2% similar) in 434 aa overlap (1-434:1-422) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKV--- 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ---------SGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: CCDS59 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQM 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 350 360 370 380 390 400 430 pF1KB7 FAPGITEKAPEEKK :::::::::::::: CCDS59 FAPGITEKAPEEKK 410 420 >>CCDS6490.1 PLIN2 gene_id:123|Hs108|chr9 (437 aa) initn: 1134 init1: 671 opt: 1170 Z-score: 1056.4 bits: 204.6 E(32554): 1.6e-52 Smith-Waterman score: 1170; 42.8% identity (80.7% similar) in 409 aa overlap (22-427:9-411) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC ::::: ::...::.::: :..:.:: :::..::..:.:: CCDS64 MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVC 10 20 30 40 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD . ::.::.:.:..:...: ::..::::::: :. :: .:::..:: ::::.::. ...:. CCDS64 EMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVAN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR .: :.. ... :..:::.::. .. ..: :.::: ..:.::::::.:....:.::: CCDS64 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG . :.: :::...: ::: ....::::. :: . : ...:::.. :. ::.:::: CCDS64 MMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLV------QKPSYYVRLG 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGV---DQKLVEGQEKL ::: .:...::...:.... .::..:... :: ... :.: ....: .::. ..:.:: CCDS64 SLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 HQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKD . :. :... : :..:::.:.. :...::::.:: .: :.:::.: :..: CCDS64 YLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQD 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 QVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWL :... .. :. ..: . ::...:.:.:..:. .. . .:.:: ...:...:::..:: CCDS64 QAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWL 350 360 370 380 390 400 420 430 pF1KB7 VGPFAPGITEKAPEEKK :::: : .:: CCDS64 VGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH 410 420 430 >>CCDS42473.1 PLIN5 gene_id:440503|Hs108|chr19 (463 aa) initn: 919 init1: 343 opt: 699 Z-score: 635.7 bits: 126.8 E(32554): 4.3e-29 Smith-Waterman score: 945; 40.0% identity (69.9% similar) in 425 aa overlap (7-431:5-387) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :: . .: : :: .::.::...::. .:: : .:...:. .: . ..: CCDS42 MSEEEAAQIPRSSVWEQDQQ-NVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSAC 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD ::. : ::. :.. :::.: .:.::.:. . : ::::::::.::.::::.: : CCDS42 RLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETV--- 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :.::::.::.... .:: .: . . .:. .:: CCDS42 ---------------VTSAKDVVASSVTGVVDLARRGRRWSVELKRSVS----------- 120 130 140 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG .::.:: :::: .:. ::.:. ::: .:. .: .:.::..::..:.:::::: CCDS42 ------HAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLG 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::: :.:. :::::.:::: .:.:::..: ::...: :.. .. :: :.:.. CCDS42 SLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHEL 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ : :.:. ::.. . :.: ..:.. :...:.::.: .: ::..:::......: CCDS42 WGEWGQRP---PESR--RRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVA 270 280 290 300 310 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP ..::.:. ::..:.. . :.:. .. ::..: ::: :. .:...: :.: .:. ::::: CCDS42 EVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGP 320 330 340 350 360 370 430 pF1KB7 FAPGITEKAPEEKK ::: ..:. :: CCDS42 FAPILVER-PEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMG 380 390 400 410 420 430 >>CCDS10353.1 PLIN1 gene_id:5346|Hs108|chr15 (522 aa) initn: 340 init1: 313 opt: 389 Z-score: 358.3 bits: 75.7 E(32554): 1.2e-13 Smith-Waterman score: 404; 24.0% identity (63.5% similar) in 367 aa overlap (10-376:6-350) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC : : . . : .: .:..:: ..:..:.::. . .:.::::..: . .:: CCDS10 MAVNKGLTLLDGDLP-EQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVC 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD .: ::::.. .. :. . .:.. .: :...:.: : ::::.:::..: :: : ::. .. CCDS10 NAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :. .:... ::...... .. . : . ::. .: . . .:. .. . ..: CCDS10 LKDTISTRLR-------SARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTR 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :... .:.: .::. :. .. :: : : . : : . :. .. . . : . :.: CCDS10 AGRLASGGADLALGSIEKVVEYLLP-PDKEESAPAP---GHQQAQ-KSPKAKPSLLSRVG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM .:.. : ... . ... :: .: .. . . . .. : .. :.. . ... .. CCDS10 ALTNTLSRYTVQ-TMA--RALEQ-GHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEV 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ . : .. . :.. . .:..... .. . . . : ... : : .. : CCDS10 RVPWLHSLAAAQEED--HEDQTDTEGEDTEEEEELETEENKFSEVAALPG-PRGLLGGVA 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP .. ... ::.:.:.. CCDS10 HTLQKT--LQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNV 340 350 360 370 380 390 434 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:47:53 2016 done: Sat Nov 5 01:47:53 2016 Total Scan time: 3.250 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]