FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7600, 434 aa 1>>>pF1KB7600 434 - 434 aa - 434 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1457+/-0.000437; mu= 9.6652+/- 0.027 mean_var=142.3101+/-27.915, 0's: 0 Z-trim(114.7): 32 B-trim: 56 in 1/54 Lambda= 0.107512 statistics sampled from 24664 (24690) to 24664 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.289), width: 16 Scan time: 8.630 The best scores are: opt bits E(85289) NP_005808 (OMIM: 602702) perilipin-3 isoform 1 [Ho ( 434) 2740 436.9 4.8e-122 NP_001157661 (OMIM: 602702) perilipin-3 isoform 2 ( 433) 2721 434.0 3.7e-121 NP_001157666 (OMIM: 602702) perilipin-3 isoform 3 ( 422) 1953 314.8 2.6e-85 NP_001113 (OMIM: 103195) perilipin-2 [Homo sapiens ( 437) 1170 193.4 9.8e-49 XP_016869748 (OMIM: 103195) PREDICTED: perilipin-2 ( 445) 1128 186.9 9.1e-47 NP_001013728 (OMIM: 613248) perilipin-5 [Homo sapi ( 463) 699 120.4 1e-26 NP_002657 (OMIM: 170290,613877) perilipin-1 [Homo ( 522) 389 72.3 3.3e-12 NP_001138783 (OMIM: 170290,613877) perilipin-1 [Ho ( 522) 389 72.3 3.3e-12 XP_005254991 (OMIM: 170290,613877) PREDICTED: peri ( 522) 389 72.3 3.3e-12 NP_001073869 (OMIM: 613247) perilipin-4 [Homo sapi (1357) 256 52.0 1.1e-05 XP_006722931 (OMIM: 613247) PREDICTED: perilipin-4 (1371) 256 52.0 1.1e-05 XP_006722929 (OMIM: 613247) PREDICTED: perilipin-4 (1372) 256 52.0 1.1e-05 XP_011526535 (OMIM: 613247) PREDICTED: perilipin-4 (1432) 256 52.0 1.2e-05 XP_016882681 (OMIM: 613247) PREDICTED: perilipin-4 (1433) 256 52.0 1.2e-05 XP_016882683 (OMIM: 613247) PREDICTED: perilipin-4 (1433) 256 52.0 1.2e-05 XP_016882682 (OMIM: 613247) PREDICTED: perilipin-4 (1433) 256 52.0 1.2e-05 >>NP_005808 (OMIM: 602702) perilipin-3 isoform 1 [Homo s (434 aa) initn: 2740 init1: 2740 opt: 2740 Z-score: 2312.0 bits: 436.9 E(85289): 4.8e-122 Smith-Waterman score: 2740; 99.8% identity (100.0% similar) in 434 aa overlap (1-434:1-434) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_005 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 370 380 390 400 410 420 430 pF1KB7 FAPGITEKAPEEKK :::::::::::::: NP_005 FAPGITEKAPEEKK 430 >>NP_001157661 (OMIM: 602702) perilipin-3 isoform 2 [Hom (433 aa) initn: 2015 init1: 2015 opt: 2721 Z-score: 2296.1 bits: 434.0 E(85289): 3.7e-121 Smith-Waterman score: 2721; 99.5% identity (99.8% similar) in 434 aa overlap (1-434:1-433) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_001 WLSWNQKQLQGPEKEPPKPE-VESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 360 370 380 390 400 410 430 pF1KB7 FAPGITEKAPEEKK :::::::::::::: NP_001 FAPGITEKAPEEKK 420 430 >>NP_001157666 (OMIM: 602702) perilipin-3 isoform 3 [Hom (422 aa) initn: 1949 init1: 1949 opt: 1953 Z-score: 1652.5 bits: 314.8 E(85289): 2.6e-85 Smith-Waterman score: 2640; 97.0% identity (97.2% similar) in 434 aa overlap (1-434:1-422) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKV--- 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------SGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQM 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP 350 360 370 380 390 400 430 pF1KB7 FAPGITEKAPEEKK :::::::::::::: NP_001 FAPGITEKAPEEKK 410 420 >>NP_001113 (OMIM: 103195) perilipin-2 [Homo sapiens] (437 aa) initn: 1134 init1: 671 opt: 1170 Z-score: 995.9 bits: 193.4 E(85289): 9.8e-49 Smith-Waterman score: 1170; 42.8% identity (80.7% similar) in 409 aa overlap (22-427:9-411) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC ::::: ::...::.::: :..:.:: :::..::..:.:: NP_001 MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVC 10 20 30 40 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD . ::.::.:.:..:...: ::..::::::: :. :: .:::..:: ::::.::. ...:. NP_001 EMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVAN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR .: :.. ... :..:::.::. .. ..: :.::: ..:.::::::.:....:.::: NP_001 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG . :.: :::...: ::: ....::::. :: . : ...:::.. :. ::.:::: NP_001 MMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLV------QKPSYYVRLG 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGV---DQKLVEGQEKL ::: .:...::...:.... .::..:... :: ... :.: ....: .::. ..:.:: NP_001 SLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 HQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKD . :. :... : :..:::.:.. :...::::.:: .: :.:::.: :..: NP_001 YLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQD 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 QVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWL :... .. :. ..: . ::...:.:.:..:. .. . .:.:: ...:...:::..:: NP_001 QAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWL 350 360 370 380 390 400 420 430 pF1KB7 VGPFAPGITEKAPEEKK :::: : .:: NP_001 VGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH 410 420 430 >>XP_016869748 (OMIM: 103195) PREDICTED: perilipin-2 iso (445 aa) initn: 1089 init1: 671 opt: 1128 Z-score: 960.6 bits: 186.9 E(85289): 9.1e-47 Smith-Waterman score: 1128; 42.2% identity (80.4% similar) in 403 aa overlap (22-421:9-405) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC ::::: ::...::.::: :..:.:: :::..::..:.:: XP_016 MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVC 10 20 30 40 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD . ::.::.:.:..:...: ::..::::::: :. :: .:::..:: ::::.::. ...:. XP_016 EMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVAN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR .: :.. ... :..:::.::. .. ..: :.::: ..:.::::::.:....:.::: XP_016 AKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG . :.: :::...: ::: ....::::. :: . : ...:::.. :. ::.:::: XP_016 MMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLV------QKPSYYVRLG 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGV---DQKLVEGQEKL ::: .:...::...:.... .::..:... :: ... :.: ....: .::. ..:.:: XP_016 SLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 HQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKD . :. :... : :..:::.:.. :...::::.:: .: :.:::.: :..: XP_016 YLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQD 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 QVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWL :... .. :. ..: . ::...:.:.:..:. .. . .:.:: ...:...:::..:: XP_016 QAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWL 350 360 370 380 390 400 420 430 pF1KB7 VGPFAPGITEKAPEEKK : : XP_016 VFDFTTIDLTSETDEIPDIIALEEENGSNNSHANGPVLSGQDVE 410 420 430 440 >>NP_001013728 (OMIM: 613248) perilipin-5 [Homo sapiens] (463 aa) initn: 919 init1: 343 opt: 699 Z-score: 600.7 bits: 120.4 E(85289): 1e-26 Smith-Waterman score: 945; 40.0% identity (69.9% similar) in 425 aa overlap (7-431:5-387) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC :: . .: : :: .::.::...::. .:: : .:...:. .: . ..: NP_001 MSEEEAAQIPRSSVWEQDQQ-NVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSAC 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD ::. : ::. :.. :::.: .:.::.:. . : ::::::::.::.::::.: : NP_001 RLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETV--- 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :.::::.::.... .:: .: . . .:. .:: NP_001 ---------------VTSAKDVVASSVTGVVDLARRGRRWSVELKRSVS----------- 120 130 140 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG .::.:: :::: .:. ::.:. ::: .:. .: .:.::..::..:.:::::: NP_001 ------HAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLG 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM ::: :.:. :::::.:::: .:.:::..: ::...: :.. .. :: :.:.. NP_001 SLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHEL 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ : :.:. ::.. . :.: ..:.. :...:.::.: .: ::..:::......: NP_001 WGEWGQRP---PESR--RRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVA 270 280 290 300 310 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP ..::.:. ::..:.. . :.:. .. ::..: ::: :. .:...: :.: .:. ::::: NP_001 EVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGP 320 330 340 350 360 370 430 pF1KB7 FAPGITEKAPEEKK ::: ..:. :: NP_001 FAPILVER-PEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMG 380 390 400 410 420 430 >>NP_002657 (OMIM: 170290,613877) perilipin-1 [Homo sapi (522 aa) initn: 340 init1: 313 opt: 389 Z-score: 340.2 bits: 72.3 E(85289): 3.3e-12 Smith-Waterman score: 404; 24.0% identity (63.5% similar) in 367 aa overlap (10-376:6-350) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC : : . . : .: .:..:: ..:..:.::. . .:.::::..: . .:: NP_002 MAVNKGLTLLDGDLP-EQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVC 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD .: ::::.. .. :. . .:.. .: :...:.: : ::::.:::..: :: : ::. .. NP_002 NAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :. .:... ::...... .. . : . ::. .: . . .:. .. . ..: NP_002 LKDTISTRLR-------SARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTR 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :... .:.: .::. :. .. :: : : . : : . :. .. . . : . :.: NP_002 AGRLASGGADLALGSIEKVVEYLLP-PDKEESAPAP---GHQQAQ-KSPKAKPSLLSRVG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM .:.. : ... . ... :: .: .. . . . .. : .. :.. . ... .. NP_002 ALTNTLSRYTVQ-TMA--RALEQ-GHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEV 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ . : .. . :.. . .:..... .. . . . : ... : : .. : NP_002 RVPWLHSLAAAQEED--HEDQTDTEGEDTEEEEELETEENKFSEVAALPG-PRGLLGGVA 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP .. ... ::.:.:.. NP_002 HTLQKT--LQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNV 340 350 360 370 380 390 >>NP_001138783 (OMIM: 170290,613877) perilipin-1 [Homo s (522 aa) initn: 340 init1: 313 opt: 389 Z-score: 340.2 bits: 72.3 E(85289): 3.3e-12 Smith-Waterman score: 404; 24.0% identity (63.5% similar) in 367 aa overlap (10-376:6-350) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC : : . . : .: .:..:: ..:..:.::. . .:.::::..: . .:: NP_001 MAVNKGLTLLDGDLP-EQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVC 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD .: ::::.. .. :. . .:.. .: :...:.: : ::::.:::..: :: : ::. .. NP_001 NAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :. .:... ::...... .. . : . ::. .: . . .:. .. . ..: NP_001 LKDTISTRLR-------SARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTR 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :... .:.: .::. :. .. :: : : . : : . :. .. . . : . :.: NP_001 AGRLASGGADLALGSIEKVVEYLLP-PDKEESAPAP---GHQQAQ-KSPKAKPSLLSRVG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM .:.. : ... . ... :: .: .. . . . .. : .. :.. . ... .. NP_001 ALTNTLSRYTVQ-TMA--RALEQ-GHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEV 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ . : .. . :.. . .:..... .. . . . : ... : : .. : NP_001 RVPWLHSLAAAQEED--HEDQTDTEGEDTEEEEELETEENKFSEVAALPG-PRGLLGGVA 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP .. ... ::.:.:.. NP_001 HTLQKT--LQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNV 340 350 360 370 380 390 >>XP_005254991 (OMIM: 170290,613877) PREDICTED: perilipi (522 aa) initn: 340 init1: 313 opt: 389 Z-score: 340.2 bits: 72.3 E(85289): 3.3e-12 Smith-Waterman score: 404; 24.0% identity (63.5% similar) in 367 aa overlap (10-376:6-350) 10 20 30 40 50 60 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC : : . . : .: .:..:: ..:..:.::. . .:.::::..: . .:: XP_005 MAVNKGLTLLDGDLP-EQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVC 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLAD .: ::::.. .. :. . .:.. .: :...:.: : ::::.:::..: :: : ::. .. XP_005 NAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 TKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSR :. .:... ::...... .. . : . ::. .: . . .:. .. . ..: XP_005 LKDTISTRLR-------SARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTR 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLG :... .:.: .::. :. .. :: : : . : : . :. .. . . : . :.: XP_005 AGRLASGGADLALGSIEKVVEYLLP-PDKEESAPAP---GHQQAQ-KSPKAKPSLLSRVG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 SLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQM .:.. : ... . ... :: .: .. . . . .. : .. :.. . ... .. XP_005 ALTNTLSRYTVQ-TMA--RALEQ-GHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEV 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQ . : .. . :.. . .:..... .. . . . : ... : : .. : XP_005 RVPWLHSLAAAQEED--HEDQTDTEGEDTEEEEELETEENKFSEVAALPG-PRGLLGGVA 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB7 QARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGP .. ... ::.:.:.. XP_005 HTLQKT--LQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNV 340 350 360 370 380 390 >>NP_001073869 (OMIM: 613247) perilipin-4 [Homo sapiens] (1357 aa) initn: 447 init1: 212 opt: 256 Z-score: 223.0 bits: 52.0 E(85289): 1.1e-05 Smith-Waterman score: 376; 27.4% identity (58.7% similar) in 431 aa overlap (5-422:945-1351) 10 20 30 pF1KB7 MSADGAEADGSTQVTVEEPVQQPSVVDRV-ASMP ::. .: :: : . .: : :: NP_001 DTVCSGVTGAVNVAKGTVQTGVDTAKTVLSGAKDAVTTGVTGAVNVAKGTVQTGVDASKA 920 930 940 950 960 970 40 50 60 70 80 90 pF1KB7 LISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPILSK-LEPQIASA .. .: : : .. ... .. . :.. :. : : ....:.. .: : . : NP_001 VLMGTKDTVFSGVTGA------MSMAKGAVQGGLDT-TKTVLTGTKDAVSAGLMGSGNVA 980 990 1000 1010 1020 100 110 120 130 140 pF1KB7 SEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGA---QEMVSSAKDTVATQLS- . .: ::. ... :: . :.... .. . : :: :. .: :: NP_001 TGATHTGLSTFQNWLPSTPATSWGGLTSSRTTDNGGEQTALSPQEAPFSGISTPPDVLSV 1030 1040 1050 1060 1070 1080 150 160 170 180 190 200 pF1KB7 ------EAVDATRGAVQSGVDKTKSVVTGGVQS-VMGSRLGQMVLSGVDTVLGKSEEWAD ::. .:.: . . . :.... : .. .... : . . .. : .: NP_001 GPEPAWEAAATTKGLATDVATFTQGAAPGREDTGLLATTHGPEEAPRLAMLQNELEGLGD 1090 1100 1110 1120 1130 1140 210 220 230 240 250 260 pF1KB7 NHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRAT :.. : :..:.: : : :..: :::::::.:. .::.:.::....:. NP_001 IFHPMNAEEQAQLAASQPGPKVLSAEQ----GSYFVRLGDLGPSFRQRAFEHAVSHLQHG 1150 1160 1170 1180 1190 1200 270 280 290 300 310 320 pF1KB7 KQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQ . .:...: ::.. . :.: ..:. ::: .: : : . . . ..: . NP_001 QFQARDTLAQLQDCFRLIEKAQQAP-----EGQPRLDQG--SGASAEDAAVQEE--RDAG 1210 1220 1230 1240 1250 330 340 350 360 370 380 pF1KB7 VESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQD : ::. ..: ::... ..: ::.::::..... : .::... .: . .: : .. NP_001 VLSRVCGLLR----QLHTAYSGLVSSLQGLPAELQQPVGRARHSLCELYGIVASAGSVEE 1260 1270 1280 1290 1300 1310 390 400 410 420 430 pF1KB7 LSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEKAPEEKK : . :.:::: : .: ..:....: . .: :..::::::: NP_001 LPAERLVQSREGVHQAWQGLEQLLEGLQHNPPLSWLVGPFALPAGGQ 1320 1330 1340 1350 434 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:47:53 2016 done: Sat Nov 5 01:47:55 2016 Total Scan time: 8.630 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]