FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7605, 299 aa 1>>>pF1KB7605 299 - 299 aa - 299 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.4864+/-0.000622; mu= -7.4165+/- 0.038 mean_var=340.6473+/-71.485, 0's: 0 Z-trim(114.1): 24 B-trim: 393 in 1/53 Lambda= 0.069490 statistics sampled from 23774 (23795) to 23774 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.279), width: 16 Scan time: 5.340 The best scores are: opt bits E(85289) NP_065080 (OMIM: 606568,615994) leucine zipper tra ( 299) 1852 199.5 6.5e-51 XP_011532140 (OMIM: 606568,615994) PREDICTED: leuc ( 282) 1738 188.1 1.7e-47 XP_016862133 (OMIM: 606568,615994) PREDICTED: leuc ( 282) 1738 188.1 1.7e-47 NP_001263307 (OMIM: 606568,615994) leucine zipper ( 282) 1738 188.1 1.7e-47 XP_006713270 (OMIM: 606568,615994) PREDICTED: leuc ( 260) 1597 173.9 2.9e-43 XP_016862134 (OMIM: 606568,615994) PREDICTED: leuc ( 308) 1569 171.2 2.3e-42 NP_001263308 (OMIM: 606568,615994) leucine zipper ( 256) 1314 145.5 1e-34 >>NP_065080 (OMIM: 606568,615994) leucine zipper transcr (299 aa) initn: 1852 init1: 1852 opt: 1852 Z-score: 1035.0 bits: 199.5 E(85289): 6.5e-51 Smith-Waterman score: 1852; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299) 10 20 30 40 50 60 pF1KB7 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 250 260 270 280 290 >>XP_011532140 (OMIM: 606568,615994) PREDICTED: leucine (282 aa) initn: 1738 init1: 1738 opt: 1738 Z-score: 973.6 bits: 188.1 E(85289): 1.7e-47 Smith-Waterman score: 1738; 100.0% identity (100.0% similar) in 282 aa overlap (18-299:1-282) 10 20 30 40 50 60 pF1KB7 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG ::::::::::::::::::::::::::::::::::::::::::: XP_011 MRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG 10 20 30 40 70 80 90 100 110 120 pF1KB7 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 230 240 250 260 270 280 >>XP_016862133 (OMIM: 606568,615994) PREDICTED: leucine (282 aa) initn: 1738 init1: 1738 opt: 1738 Z-score: 973.6 bits: 188.1 E(85289): 1.7e-47 Smith-Waterman score: 1738; 100.0% identity (100.0% similar) in 282 aa overlap (18-299:1-282) 10 20 30 40 50 60 pF1KB7 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG ::::::::::::::::::::::::::::::::::::::::::: XP_016 MRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG 10 20 30 40 70 80 90 100 110 120 pF1KB7 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 230 240 250 260 270 280 >>NP_001263307 (OMIM: 606568,615994) leucine zipper tran (282 aa) initn: 1738 init1: 1738 opt: 1738 Z-score: 973.6 bits: 188.1 E(85289): 1.7e-47 Smith-Waterman score: 1738; 100.0% identity (100.0% similar) in 282 aa overlap (18-299:1-282) 10 20 30 40 50 60 pF1KB7 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG ::::::::::::::::::::::::::::::::::::::::::: NP_001 MRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG 10 20 30 40 70 80 90 100 110 120 pF1KB7 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 230 240 250 260 270 280 >>XP_006713270 (OMIM: 606568,615994) PREDICTED: leucine (260 aa) initn: 1597 init1: 1597 opt: 1597 Z-score: 897.6 bits: 173.9 E(85289): 2.9e-43 Smith-Waterman score: 1597; 100.0% identity (100.0% similar) in 259 aa overlap (1-259:1-259) 10 20 30 40 50 60 pF1KB7 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED ::::::::::::::::::: XP_006 ATAKHDLLRVQEQLHMAEKI 250 260 >>XP_016862134 (OMIM: 606568,615994) PREDICTED: leucine (308 aa) initn: 1567 init1: 1567 opt: 1569 Z-score: 881.5 bits: 171.2 E(85289): 2.3e-42 Smith-Waterman score: 1569; 97.7% identity (98.9% similar) in 264 aa overlap (36-299:47-308) 10 20 30 40 50 60 pF1KB7 LNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVV ::. .. :::::::::::::::::::::: XP_016 QWINRKGRQRKSIKLYPTHPLVTFPRSWAKFQE--KALLVEDTFTIDEVSEVLNGLQAVV 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB7 HSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSS 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB7 NKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKL 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB7 EKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKH 200 210 220 230 240 250 250 260 270 280 290 pF1KB7 DLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 260 270 280 290 300 >>NP_001263308 (OMIM: 606568,615994) leucine zipper tran (256 aa) initn: 1312 init1: 1312 opt: 1314 Z-score: 744.4 bits: 145.5 E(85289): 1e-34 Smith-Waterman score: 1314; 97.3% identity (98.7% similar) in 224 aa overlap (36-259:34-255) 10 20 30 40 50 60 pF1KB7 LNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVV ::. .. :::::::::::::::::::::: NP_001 QDPGKMGRQRKSIKLYPTHPLVTFPRSWAKFQE--KALLVEDTFTIDEVSEVLNGLQAVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 EKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKH 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 DLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED :::::::::::::: NP_001 DLLRVQEQLHMAEKI 250 299 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:56:42 2016 done: Fri Nov 4 08:56:43 2016 Total Scan time: 5.340 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]