FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7615, 304 aa 1>>>pF1KB7615 304 - 304 aa - 304 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0899+/-0.000908; mu= 5.1121+/- 0.055 mean_var=219.5131+/-44.827, 0's: 0 Z-trim(114.1): 178 B-trim: 80 in 1/51 Lambda= 0.086565 statistics sampled from 14517 (14716) to 14517 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.452), width: 16 Scan time: 2.550 The best scores are: opt bits E(32554) CCDS34605.1 MEOX2 gene_id:4223|Hs108|chr7 ( 304) 2101 274.4 7.3e-74 CCDS11466.1 MEOX1 gene_id:4222|Hs108|chr17 ( 254) 525 77.5 1.1e-14 CCDS42343.1 MEOX1 gene_id:4222|Hs108|chr17 ( 139) 519 76.5 1.3e-14 >>CCDS34605.1 MEOX2 gene_id:4223|Hs108|chr7 (304 aa) initn: 2101 init1: 2101 opt: 2101 Z-score: 1439.6 bits: 274.4 E(32554): 7.3e-74 Smith-Waterman score: 2101; 100.0% identity (100.0% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB7 MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ASQHHRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSGGPPEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ASQHHRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQMSSPPSAARHSLCLQPDSGGPPEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GSSPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GSSPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSIANEDSHDSDHSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 KWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSIANEDSHDSDHSSE 250 260 270 280 290 300 pF1KB7 HAHL :::: CCDS34 HAHL >>CCDS11466.1 MEOX1 gene_id:4222|Hs108|chr17 (254 aa) initn: 629 init1: 487 opt: 525 Z-score: 376.9 bits: 77.5 E(32554): 1.1e-14 Smith-Waterman score: 624; 47.8% identity (64.3% similar) in 255 aa overlap (4-249:17-233) 10 20 30 pF1KB7 MEHPLFGCLRSPHAT---AQGLHPFSQSSLALHGRSDHMS-----YP :..::::.::. :.:: . . ...: . : .. :: CCDS11 MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 ELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHHQQQQHQALQTNWHLPQMSS ..:.: . . :.:: .:. :: :. :::.: CCDS11 DFSASCLAATPHSLPQEEHIFTEQHPA-------------FPQSP------NWHFPV--- 70 80 90 100 110 120 130 140 150 pF1KB7 PPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPGD-YGRQALSPAE : ::. .:.:: : ::. ..:::: ::. ::: :: . . : CCDS11 --SDARR----RPNSG--PAGGSKE----MGTSSLGLVDTTGG---PGDDYGVLGSTANE 100 110 120 130 140 160 170 180 190 200 210 pF1KB7 AEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRY .::.:. .:: .:::.::. : : .:: :::::::::::.::::::::::::::::::: CCDS11 TEKKSSRRRK-ESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRY 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB7 EIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAA ::::::::.:::::::::::::::::::::: CCDS11 EIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDSTASPSSE 210 220 230 240 250 280 290 300 pF1KB7 TLQQTGDSIANEDSHDSDHSSEHAHL >>CCDS42343.1 MEOX1 gene_id:4222|Hs108|chr17 (139 aa) initn: 520 init1: 487 opt: 519 Z-score: 376.1 bits: 76.5 E(32554): 1.3e-14 Smith-Waterman score: 519; 70.8% identity (84.2% similar) in 120 aa overlap (131-249:3-118) 110 120 130 140 150 pF1KB7 PSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPGD-YGRQALSPAEA .:::: :: .::: :: . . :. CCDS42 MGTSSLGLVDTTG---GPGDDYGVLGSTANET 10 20 160 170 180 190 200 210 pF1KB7 EKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYE ::.:. .:...:::.::. : : .:: :::::::::::.:::::::::::::::::::: CCDS42 EKKSS-RRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYE 30 40 50 60 70 80 220 230 240 250 260 270 pF1KB7 IAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAAT :::::::.:::::::::::::::::::::: CCDS42 IAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDSTASPSSE 90 100 110 120 130 304 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:19:56 2016 done: Fri Nov 4 21:19:56 2016 Total Scan time: 2.550 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]