FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7617, 307 aa 1>>>pF1KB7617 307 - 307 aa - 307 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2535+/-0.000484; mu= 6.5688+/- 0.030 mean_var=128.0623+/-25.314, 0's: 0 Z-trim(111.9): 11 B-trim: 96 in 2/54 Lambda= 0.113335 statistics sampled from 20644 (20652) to 20644 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.596), E-opt: 0.2 (0.242), width: 16 Scan time: 4.950 The best scores are: opt bits E(85289) XP_016860736 (OMIM: 603525) PREDICTED: N-myc-inter ( 307) 1967 333.2 4.1e-91 XP_005246998 (OMIM: 603525) PREDICTED: N-myc-inter ( 307) 1967 333.2 4.1e-91 NP_004679 (OMIM: 603525) N-myc-interactor [Homo sa ( 307) 1967 333.2 4.1e-91 NP_001317159 (OMIM: 600735) interferon-induced 35 ( 286) 390 75.3 1.6e-13 XP_016880074 (OMIM: 600735) PREDICTED: interferon- ( 266) 388 74.9 1.9e-13 NP_005524 (OMIM: 600735) interferon-induced 35 kDa ( 288) 388 75.0 2.1e-13 XP_016880073 (OMIM: 600735) PREDICTED: interferon- ( 268) 386 74.6 2.4e-13 >>XP_016860736 (OMIM: 603525) PREDICTED: N-myc-interacto (307 aa) initn: 1967 init1: 1967 opt: 1967 Z-score: 1756.7 bits: 333.2 E(85289): 4.1e-91 Smith-Waterman score: 1967; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307) 10 20 30 40 50 60 pF1KB7 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 MSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 IHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQP 250 260 270 280 290 300 pF1KB7 HIAYFEE ::::::: XP_016 HIAYFEE >>XP_005246998 (OMIM: 603525) PREDICTED: N-myc-interacto (307 aa) initn: 1967 init1: 1967 opt: 1967 Z-score: 1756.7 bits: 333.2 E(85289): 4.1e-91 Smith-Waterman score: 1967; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307) 10 20 30 40 50 60 pF1KB7 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 MSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 IHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQP 250 260 270 280 290 300 pF1KB7 HIAYFEE ::::::: XP_005 HIAYFEE >>NP_004679 (OMIM: 603525) N-myc-interactor [Homo sapien (307 aa) initn: 1967 init1: 1967 opt: 1967 Z-score: 1756.7 bits: 333.2 E(85289): 4.1e-91 Smith-Waterman score: 1967; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307) 10 20 30 40 50 60 pF1KB7 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 MSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 IHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQP 250 260 270 280 290 300 pF1KB7 HIAYFEE ::::::: NP_004 HIAYFEE >>NP_001317159 (OMIM: 600735) interferon-induced 35 kDa (286 aa) initn: 249 init1: 193 opt: 390 Z-score: 363.6 bits: 75.3 E(85289): 1.6e-13 Smith-Waterman score: 390; 29.2% identity (64.2% similar) in 288 aa overlap (23-305:6-281) 10 20 30 40 50 60 pF1KB7 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI : ..: .: .. ...: ..:.:. :: .. :. .. NP_001 MSAPLDAALHALQEEQARLKMRLW-DLQQLRKELGDSPKD-KV 10 20 30 40 70 80 90 100 110 120 pF1KB7 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS ..:. . : . . .: .. :. . .. . :.:::::. .::..:.. NP_001 PFSVPKIPLVFRG-----HTQQDPEVPKSLVSNLRIHCPLLAGSALITFDDPKVAEQVLQ 50 60 70 80 90 130 140 150 160 170 pF1KB7 MSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLR--EDQMRDKLE ...: ..... :.: ..:. : . .:. ..: .. :: .: .:: :... :::: NP_001 QKEHTINMEECRLRVQVQPLELPMVTTIQMSSQLSGRRVLVTGFPASLRLSEEELLDKLE 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 LSFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEY--PLYINQTCHRVTVS . :.:.:::::.:: . ::... :.. :::... . .. :: .:. : :: NP_001 IFFGKTRNGGGDVDV--RELLPGSVMLGFARDGVAQRLCQIGQFTVPLGGQQVPLR--VS 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 PYTEIHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKC- ::.. ...: .: : :.::. .. : .: ..:...::::. :::::... NP_001 PYVNGEIQKAEIRSQPVPRSVLVLNIPDI-LDGPELHDVLEIHFQKPTRGGGEVEALTVV 220 230 240 250 260 270 300 pF1KB7 SLGQPHIAYFEE :: .: : NP_001 PQGQQGLAVFTSESG 280 >>XP_016880074 (OMIM: 600735) PREDICTED: interferon-indu (266 aa) initn: 249 init1: 193 opt: 388 Z-score: 362.3 bits: 74.9 E(85289): 1.9e-13 Smith-Waterman score: 388; 29.9% identity (64.6% similar) in 268 aa overlap (43-305:5-261) 20 30 40 50 60 70 pF1KB7 KEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQIKEDIPETKMKFL ..:.:. :: .. :. .. ..:. . : XP_016 MRLWDLQQLRKELGDSPKD-KVPFSVPKIPLVFR 10 20 30 80 90 100 110 120 130 pF1KB7 SVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVSMSKHHVQIKDVN . . .: .. :. . .. . :.:::::. .::..:.....: ..... XP_016 G-----HTQQDPEVPKSLVSNLRIHCPLLAGSALITFDDPKVAEQVLQQKEHTINMEECR 40 50 60 70 80 140 150 160 170 180 190 pF1KB7 LEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLR--EDQMRDKLELSFSKSRNGGGE :.: ..:. : . .:. ..: .. :: .: .:: :... ::::. :.:.:::::. XP_016 LRVQVQPLELPMVTTIQMSSQLSGRRVLVTGFPASLRLSEEELLDKLEIFFGKTRNGGGD 90 100 110 120 130 140 200 210 220 230 240 pF1KB7 VDRVDYDRQSGSAVITFVEIGVADKILKKKEY--PLYINQTCHRVTVSPYTEIHLKKYQI :: . ::... :.. :::... . .. :: .:. : ::::.. ...: .: XP_016 VDV--RELLPGSVMLGFARDGVAQRLCQIGQFTVPLGGQQVPLR--VSPYVNGEIQKAEI 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB7 FSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKC-SLGQPHIAYFEE : :.::. .. : .: ..:...::::. :::::... :: .: : XP_016 RSQPVPRSVLVLNIPDI-LDGPELHDVLEIHFQKPTRGGGEVEALTVVPQGQQGLAVFTS 210 220 230 240 250 260 XP_016 ESG >>NP_005524 (OMIM: 600735) interferon-induced 35 kDa pro (288 aa) initn: 240 init1: 113 opt: 388 Z-score: 361.8 bits: 75.0 E(85289): 2.1e-13 Smith-Waterman score: 388; 28.6% identity (64.5% similar) in 290 aa overlap (23-305:6-283) 10 20 30 40 50 60 pF1KB7 MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQI : ..: .: .. ...: ..:.:. :: .. :. .. NP_005 MSAPLDAALHALQEEQARLKMRLW-DLQQLRKELGDSPKD-KV 10 20 30 40 70 80 90 100 110 120 pF1KB7 KEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVS ..:. . : . . .: .. :. . .. . :.:::::. .::..:.. NP_005 PFSVPKIPLVFRG-----HTQQDPEVPKSLVSNLRIHCPLLAGSALITFDDPKVAEQVLQ 50 60 70 80 90 130 140 150 160 170 pF1KB7 MSKHHVQIKDVNLEVTAKPV--PLNSGVRFQVYVEVSKMKINVTEIPDTLR--EDQMRDK ...: ..... :.: ..:. :. . .. .. ..: .. :: .: .:: :... :: NP_005 QKEHTINMEECRLRVQVQPLELPMVTTIQVMMSSQLSGRRVLVTGFPASLRLSEEELLDK 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 LELSFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEY--PLYINQTCHRVT ::. :.:.:::::.:: . ::... :.. :::... . .. :: .:. : NP_005 LEIFFGKTRNGGGDVDV--RELLPGSVMLGFARDGVAQRLCQIGQFTVPLGGQQVPLR-- 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 VSPYTEIHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVK ::::.. ...: .: : :.::. .. : .: ..:...::::. :::::... NP_005 VSPYVNGEIQKAEIRSQPVPRSVLVLNIPDI-LDGPELHDVLEIHFQKPTRGGGEVEALT 220 230 240 250 260 270 300 pF1KB7 C-SLGQPHIAYFEE :: .: : NP_005 VVPQGQQGLAVFTSESG 280 >>XP_016880073 (OMIM: 600735) PREDICTED: interferon-indu (268 aa) initn: 240 init1: 113 opt: 386 Z-score: 360.5 bits: 74.6 E(85289): 2.4e-13 Smith-Waterman score: 386; 29.3% identity (64.8% similar) in 270 aa overlap (43-305:5-263) 20 30 40 50 60 70 pF1KB7 KEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQIKEDIPETKMKFL ..:.:. :: .. :. .. ..:. . : XP_016 MRLWDLQQLRKELGDSPKD-KVPFSVPKIPLVFR 10 20 30 80 90 100 110 120 130 pF1KB7 SVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVSMSKHHVQIKDVN . . .: .. :. . .. . :.:::::. .::..:.....: ..... XP_016 G-----HTQQDPEVPKSLVSNLRIHCPLLAGSALITFDDPKVAEQVLQQKEHTINMEECR 40 50 60 70 80 140 150 160 170 180 pF1KB7 LEVTAKPV--PLNSGVRFQVYVEVSKMKINVTEIPDTLR--EDQMRDKLELSFSKSRNGG :.: ..:. :. . .. .. ..: .. :: .: .:: :... ::::. :.:.:::: XP_016 LRVQVQPLELPMVTTIQVMMSSQLSGRRVLVTGFPASLRLSEEELLDKLEIFFGKTRNGG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB7 GEVDRVDYDRQSGSAVITFVEIGVADKILKKKEY--PLYINQTCHRVTVSPYTEIHLKKY :.:: . ::... :.. :::... . .. :: .:. : ::::.. ...: XP_016 GDVDV--RELLPGSVMLGFARDGVAQRLCQIGQFTVPLGGQQVPLR--VSPYVNGEIQKA 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB7 QIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKC-SLGQPHIAYF .: : :.::. .. : .: ..:...::::. :::::... :: .: : XP_016 EIRSQPVPRSVLVLNIPDI-LDGPELHDVLEIHFQKPTRGGGEVEALTVVPQGQQGLAVF 210 220 230 240 250 260 pF1KB7 EE XP_016 TSESG 307 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:56:28 2016 done: Sat Nov 5 18:56:28 2016 Total Scan time: 4.950 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]