FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7619, 308 aa 1>>>pF1KB7619 308 - 308 aa - 308 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4536+/-0.000337; mu= 14.7511+/- 0.021 mean_var=65.6499+/-13.428, 0's: 0 Z-trim(115.8): 5 B-trim: 1265 in 3/51 Lambda= 0.158291 statistics sampled from 26484 (26489) to 26484 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.311), width: 16 Scan time: 6.630 The best scores are: opt bits E(85289) NP_001507 (OMIM: 601750) general transcription fac ( 308) 2060 479.0 5.2e-135 NP_001258796 (OMIM: 601750) general transcription ( 267) 1788 416.8 2.3e-116 XP_016874717 (OMIM: 601750) PREDICTED: general tra ( 162) 1094 258.3 7.7e-69 NP_001258797 (OMIM: 601750) general transcription ( 162) 1094 258.3 7.7e-69 NP_001258795 (OMIM: 601750) general transcription ( 265) 1066 252.0 9.9e-67 >>NP_001507 (OMIM: 601750) general transcription factor (308 aa) initn: 2060 init1: 2060 opt: 2060 Z-score: 2544.8 bits: 479.0 E(85289): 5.2e-135 Smith-Waterman score: 2060; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB7 MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAK 250 260 270 280 290 300 pF1KB7 KKKLKVSA :::::::: NP_001 KKKLKVSA >>NP_001258796 (OMIM: 601750) general transcription fact (267 aa) initn: 1788 init1: 1788 opt: 1788 Z-score: 2210.0 bits: 416.8 E(85289): 2.3e-116 Smith-Waterman score: 1788; 100.0% identity (100.0% similar) in 267 aa overlap (42-308:1-267) 20 30 40 50 60 70 pF1KB7 VIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLY :::::::::::::::::::::::::::::: NP_001 MVLGNSHLFMNRSNKLAVIASHIQESRFLY 10 20 30 80 90 100 110 120 130 pF1KB7 PGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKSDIKGQHTET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKSDIKGQHTET 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB7 LLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILI 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB7 DACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDY 160 170 180 190 200 210 260 270 280 290 300 pF1KB7 RAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKVSA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKVSA 220 230 240 250 260 >>XP_016874717 (OMIM: 601750) PREDICTED: general transcr (162 aa) initn: 1094 init1: 1094 opt: 1094 Z-score: 1356.9 bits: 258.3 E(85289): 7.7e-69 Smith-Waterman score: 1094; 100.0% identity (100.0% similar) in 162 aa overlap (147-308:1-162) 120 130 140 150 160 170 pF1KB7 DLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMN :::::::::::::::::::::::::::::: XP_016 MNKEVKDNQEMKSRILVIKAAEDSALQYMN 10 20 30 180 190 200 210 220 230 pF1KB7 FMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQD 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB7 QRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPV 100 110 120 130 140 150 300 pF1KB7 LKAKKKKLKVSA :::::::::::: XP_016 LKAKKKKLKVSA 160 >>NP_001258797 (OMIM: 601750) general transcription fact (162 aa) initn: 1094 init1: 1094 opt: 1094 Z-score: 1356.9 bits: 258.3 E(85289): 7.7e-69 Smith-Waterman score: 1094; 100.0% identity (100.0% similar) in 162 aa overlap (147-308:1-162) 120 130 140 150 160 170 pF1KB7 DLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMN :::::::::::::::::::::::::::::: NP_001 MNKEVKDNQEMKSRILVIKAAEDSALQYMN 10 20 30 180 190 200 210 220 230 pF1KB7 FMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQD 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB7 QRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPV 100 110 120 130 140 150 300 pF1KB7 LKAKKKKLKVSA :::::::::::: NP_001 LKAKKKKLKVSA 160 >>NP_001258795 (OMIM: 601750) general transcription fact (265 aa) initn: 1776 init1: 1066 opt: 1066 Z-score: 1319.0 bits: 252.0 E(85289): 9.9e-67 Smith-Waterman score: 1694; 86.0% identity (86.0% similar) in 308 aa overlap (1-308:1-265) 10 20 30 40 50 60 pF1KB7 MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNV :::::::::::::::::::::::::::::::::::::::::: NP_001 KSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRIL------------------ 130 140 150 160 190 200 210 220 230 240 pF1KB7 IFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQ ::::::::::::::::::::::::::::::::::: NP_001 -------------------------ACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQ 170 180 190 250 260 270 280 290 300 pF1KB7 LILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAK 200 210 220 230 240 250 pF1KB7 KKKLKVSA :::::::: NP_001 KKKLKVSA 260 308 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:58:07 2016 done: Fri Nov 4 08:58:08 2016 Total Scan time: 6.630 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]