FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7621, 313 aa 1>>>pF1KB7621 313 - 313 aa - 313 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3267+/-0.000375; mu= -1.8846+/- 0.024 mean_var=441.0163+/-88.307, 0's: 0 Z-trim(126.3): 144 B-trim: 0 in 0/61 Lambda= 0.061073 statistics sampled from 51779 (51952) to 51779 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.843), E-opt: 0.2 (0.609), width: 16 Scan time: 7.770 The best scores are: opt bits E(85289) NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 2189 205.9 8.5e-53 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 2157 203.1 6.1e-52 XP_011533179 (OMIM: 600297) PREDICTED: homeobox pr ( 273) 1593 153.4 5e-37 XP_011533178 (OMIM: 600297) PREDICTED: homeobox pr ( 281) 1567 151.1 2.5e-36 XP_011533180 (OMIM: 600297) PREDICTED: homeobox pr ( 204) 923 94.2 2.5e-19 XP_011533181 (OMIM: 600297) PREDICTED: homeobox pr ( 196) 906 92.6 6.8e-19 NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 584 64.4 2.8e-10 NP_005184 (OMIM: 300025) homeobox protein CDX-4 [H ( 284) 453 52.9 8.9e-07 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 368 45.5 0.00017 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 334 42.4 0.0012 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 334 42.4 0.0012 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 334 42.7 0.0017 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 334 42.7 0.0017 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 334 42.7 0.0017 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 334 42.7 0.0017 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 334 42.7 0.0017 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 334 42.7 0.0017 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 334 42.7 0.0017 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 334 42.7 0.0017 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 322 41.4 0.0027 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 319 41.1 0.0032 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 313 40.6 0.0044 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 309 40.1 0.005 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 309 40.1 0.005 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 309 40.1 0.005 NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328) 308 40.2 0.0068 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 305 39.8 0.0069 NP_005513 (OMIM: 142955,601536) homeobox protein H ( 335) 304 39.9 0.0088 >>NP_001256 (OMIM: 600297) homeobox protein CDX-2 [Homo (313 aa) initn: 2189 init1: 2189 opt: 2189 Z-score: 1068.9 bits: 205.9 E(85289): 8.5e-53 Smith-Waterman score: 2189; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB7 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 ERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVL 250 260 270 280 290 300 310 pF1KB7 GPTGGVLNPTVTQ ::::::::::::: NP_001 GPTGGVLNPTVTQ 310 >>XP_011533177 (OMIM: 600297) PREDICTED: homeobox protei (321 aa) initn: 1597 init1: 1288 opt: 2157 Z-score: 1053.5 bits: 203.1 E(85289): 6.1e-52 Smith-Waterman score: 2157; 97.2% identity (97.2% similar) in 321 aa overlap (1-313:1-321) 10 20 30 40 50 60 pF1KB7 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 --------VKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKI :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 WFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASV 250 260 270 280 290 300 300 310 pF1KB7 SGSVPGVLGPTGGVLNPTVTQ :::::::::::::::::::: XP_011 PGSVPGVLGPTGGVLNPTVTQ 310 320 >>XP_011533179 (OMIM: 600297) PREDICTED: homeobox protei (273 aa) initn: 1586 init1: 1586 opt: 1593 Z-score: 785.7 bits: 153.4 E(85289): 5e-37 Smith-Waterman score: 1593; 95.9% identity (97.5% similar) in 243 aa overlap (1-243:1-240) 10 20 30 40 50 60 pF1KB7 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAK :::::::::::::::::::::::::::::::::::::::::::::::: .: : : :. XP_011 VKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSER-LKSGF--RTAE 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 ERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVL .:. XP_011 QRRGKSTRRSCSSNSSSSHHSRLRRHHSLPSLSQVL 240 250 260 270 >>XP_011533178 (OMIM: 600297) PREDICTED: homeobox protei (281 aa) initn: 1478 init1: 1288 opt: 1567 Z-score: 773.2 bits: 151.1 E(85289): 2.5e-36 Smith-Waterman score: 1567; 92.8% identity (94.4% similar) in 251 aa overlap (1-243:1-248) 10 20 30 40 50 60 pF1KB7 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 --------VKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKI :::::::::::::::::::::::::::::::::::::::::::::::: .: XP_011 ALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSER-LKS 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 WFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASV : : :..:. XP_011 GF--RTAEQRRGKSTRRSCSSNSSSSHHSRLRRHHSLPSLSQVL 240 250 260 270 280 >>XP_011533180 (OMIM: 600297) PREDICTED: homeobox protei (204 aa) initn: 904 init1: 904 opt: 923 Z-score: 468.1 bits: 94.2 E(85289): 2.5e-19 Smith-Waterman score: 923; 89.2% identity (91.8% similar) in 158 aa overlap (157-313:47-204) 130 140 150 160 170 180 pF1KB7 AAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKP-AQQSLGSQVKTRT ::::. . : :. : : .: ::::: XP_011 YSQLQLYKSKRPLGAVSGHRFLRHCAHARESPGGNAADRGEGHRSASALTSPSSTVKTRT 20 30 40 50 60 70 190 200 210 220 230 240 pF1KB7 KDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKIN 80 90 100 110 120 130 250 260 270 280 290 300 pF1KB7 KKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVLGPTGG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_011 KKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVPGSVPGVLGPTGG 140 150 160 170 180 190 310 pF1KB7 VLNPTVTQ :::::::: XP_011 VLNPTVTQ 200 >>XP_011533181 (OMIM: 600297) PREDICTED: homeobox protei (196 aa) initn: 898 init1: 898 opt: 906 Z-score: 460.2 bits: 92.6 E(85289): 6.8e-19 Smith-Waterman score: 906; 87.9% identity (91.1% similar) in 157 aa overlap (157-313:47-196) 130 140 150 160 170 180 pF1KB7 AAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQVKTRTK ::::. . : :. ..:::::: XP_011 YSQLQLYKSKRPLGAVSGHRFLRHCAHARESPGGNAADRGEGHRS-------ASVKTRTK 20 30 40 50 60 190 200 210 220 230 240 pF1KB7 DKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINK 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB7 KKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVLGPTGGV :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_011 KKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVPGSVPGVLGPTGGV 130 140 150 160 170 180 310 pF1KB7 LNPTVTQ ::::::: XP_011 LNPTVTQ 190 >>NP_001795 (OMIM: 600746) homeobox protein CDX-1 [Homo (265 aa) initn: 549 init1: 485 opt: 584 Z-score: 305.4 bits: 64.4 E(85289): 2.8e-10 Smith-Waterman score: 744; 49.3% identity (64.9% similar) in 282 aa overlap (1-274:1-238) 10 20 30 40 50 pF1KB7 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNF------VSPPQYPDYGGYHVAAAAAAAAN :::.:.:::: .::. .: .. :.:.:: . .::::::...: .. NP_001 MYVGYVLDKDSPVYPGPARPAS-LGLGPQAYGPPAPPPAPPQYPDFSSY---------SH 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LDSAQSPGPSWPAAYGAPLREDWNG-YAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADY .. : .: .: : . :: ..:: . :.:: :: :: :::. .... : :. NP_001 VEPAPAPPTAWGAPFPAP-KDDWAAAYGPGPAAPAA----------SPAS-LAFGPPPDF 60 70 80 90 120 130 140 150 160 170 pF1KB7 HPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKP- : : :. .: ::: :: :. :::.:: . ::::. NP_001 SPVPAP------PGPGP----GLLAQPLGGPGTPS--------SPGAQRPTPYEWMRRSV 100 110 120 130 140 180 190 200 210 220 230 pF1KB7 AQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKI : . :.. :::::::::::::::::::::::::::::::::::.::::.:::.:::::: NP_001 AAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKI 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB7 WFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASV :::::::::::.:::: :::::::::: : :: NP_001 WFQNRRAKERKVNKKK---QQQQQPPQPPMAHDITATPA-GPSLGGLCPSNTSLLATSSP 210 220 230 240 250 300 310 pF1KB7 SGSVPGVLGPTGGVLNPTVTQ NP_001 MPVKEEFLP 260 >>NP_005184 (OMIM: 300025) homeobox protein CDX-4 [Homo (284 aa) initn: 551 init1: 384 opt: 453 Z-score: 242.7 bits: 52.9 E(85289): 8.9e-07 Smith-Waterman score: 549; 39.9% identity (62.7% similar) in 303 aa overlap (1-293:1-283) 10 20 30 40 50 60 pF1KB7 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS :: : ::.:...:::... :: . : . .. : . . . ::: : . . . NP_005 MYGSCLLEKEAGMYPGTLMSPGGDGTAGTGGTGGGGSP-MPASNFAAAPAFSHYMGYPHM 10 20 30 40 50 70 80 90 100 110 pF1KB7 PG--PSWPA--AYGAPL---REDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADY :. : ::. ..:.: ::::. : :: ... ... .. ... :::: . : .:: NP_005 PSMDPHWPSLGVWGSPYSPPREDWSVY-PGPSSTMGTVPVNDVTS-SPAA---FCS-TDY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 HPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPA . : .. :. :.: .: : : ::. ::. .:.. :::: . NP_005 S-NLGPVGGGTSGSSLPGQAGG---SLVPTDAG-----AAKASSPSRSRHSPYAWMRKTV 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 QQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIW : . : :::::.::::::::::::::::::: .:::::.::.:::..::::::::::: NP_005 QVT-G---KTRTKEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIW 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 FQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPL---SPVSSLQA ::::::::::. :::..: ... : :. . ..: . .:. :. NP_005 FQNRRAKERKMIKKKISQFENSGGSVQSDSDSISPGELPNTFFTTPSAVRGFQPIEIQQV 230 240 250 260 270 280 300 310 pF1KB7 SVSGSVPGVLGPTGGVLNPTVTQ :: NP_005 IVSE >>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa) initn: 314 init1: 275 opt: 368 Z-score: 201.6 bits: 45.5 E(85289): 0.00017 Smith-Waterman score: 377; 32.5% identity (53.9% similar) in 271 aa overlap (20-283:62-319) 10 20 30 40 pF1KB7 MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAA :.:: . : :. .: .:: NP_002 ADGGPGGGPGYQQPPAPPTQHLPLQQPQLPHAGG-GREPTASYYAPRTAREPAYPAAALY 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB7 AAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSS : . :.: : :. : : . : : :.. ::::.. . .. . NP_002 PAHGAADTAYPYGYRGGASPGRPPQ-------PEQPPAQAKGPAHGLHA---SHVLQPQL 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 PADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWM : .:. : :.. ::: :. . . . .: : : :. :.. . :: NP_002 PPPLQPRAVPPAAPRRCEAAP--ATPGVPAGGSAPACPLLLADKSPLGLKGKEPVVYPWM 150 160 170 180 190 170 180 190 200 210 220 pF1KB7 RKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQ .: .... . . . :..:: .: ::::::::..::.: ::. :.: :: ::::: NP_002 KKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQ 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB7 VKIWFQNRRAKERKINK---KKLQQQQQQQPPQPPP--PPPQPPQ--PQPGPLRSVPEPL ::::::::: : .: .: :...... . :: : :. :.: : :.: : NP_002 VKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQSPHLHPHPHPSTSTPVPS 260 270 280 290 300 310 290 300 310 pF1KB7 SPVSSLQASVSGSVPGVLGPTGGVLNPTVTQ : NP_002 SI 320 >>NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 327 init1: 284 opt: 334 Z-score: 186.4 bits: 42.4 E(85289): 0.0012 Smith-Waterman score: 334; 32.6% identity (58.6% similar) in 181 aa overlap (106-284:74-252) 80 90 100 110 120 130 pF1KB7 DWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPHHHPHHPAA--APSCA : .. . : . ::::.. . :. NP_705 GFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPL 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB7 SGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVY :: . .:.::. . : . : .... . ::.: .... . . . :..: NP_705 SGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAY 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB7 TDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQ : .: :::::::::.::.: ::. :.: .: :::::.:::::::: : .: ..: . . NP_705 TRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK--DHRLPNTK 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB7 QQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVLGPTGGVLNPTVTQ .. : : :: .. . .: NP_705 VRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 230 240 250 260 313 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:00:12 2016 done: Fri Nov 4 09:00:13 2016 Total Scan time: 7.770 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]