FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7622, 368 aa 1>>>pF1KB7622 368 - 368 aa - 368 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5333+/-0.000416; mu= 6.1138+/- 0.025 mean_var=205.0987+/-42.574, 0's: 0 Z-trim(118.3): 2020 B-trim: 140 in 1/56 Lambda= 0.089556 statistics sampled from 28831 (31113) to 28831 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.365), width: 16 Scan time: 8.790 The best scores are: opt bits E(85289) NP_008896 (OMIM: 194534) zinc finger protein 24 is ( 368) 2534 340.2 4.5e-93 XP_005258398 (OMIM: 194534) PREDICTED: zinc finger ( 368) 2534 340.2 4.5e-93 NP_001295052 (OMIM: 194534) zinc finger protein 24 ( 193) 1281 178.0 1.6e-44 NP_001309215 (OMIM: 609600) zinc finger protein 39 ( 335) 1201 167.9 3e-41 XP_016881177 (OMIM: 609600) PREDICTED: zinc finger ( 335) 1201 167.9 3e-41 XP_016881176 (OMIM: 609600) PREDICTED: zinc finger ( 335) 1201 167.9 3e-41 NP_001309219 (OMIM: 609600) zinc finger protein 39 ( 335) 1201 167.9 3e-41 XP_006722495 (OMIM: 609600) PREDICTED: zinc finger ( 335) 1201 167.9 3e-41 NP_001128688 (OMIM: 610794) zinc finger and SCAN d ( 406) 1164 163.2 9.3e-40 XP_016866685 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 XP_011513113 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 XP_011513110 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 XP_011513111 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 NP_112161 (OMIM: 610794) zinc finger and SCAN doma ( 406) 1164 163.2 9.3e-40 XP_011513115 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 XP_011513109 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 XP_005249353 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 XP_005249352 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 XP_011513114 (OMIM: 610794) PREDICTED: zinc finger ( 406) 1164 163.2 9.3e-40 NP_001128687 (OMIM: 610794) zinc finger and SCAN d ( 406) 1164 163.2 9.3e-40 NP_001230170 (OMIM: 610794) zinc finger and SCAN d ( 406) 1164 163.2 9.3e-40 NP_665916 (OMIM: 610794) zinc finger and SCAN doma ( 406) 1164 163.2 9.3e-40 NP_665699 (OMIM: 609600) zinc finger protein 396 i ( 333) 1064 150.2 6.3e-36 NP_006290 (OMIM: 602246) zinc finger and SCAN doma ( 394) 1063 150.2 7.7e-36 XP_016866756 (OMIM: 602246) PREDICTED: zinc finger ( 394) 1063 150.2 7.7e-36 NP_001186409 (OMIM: 602246) zinc finger and SCAN d ( 394) 1063 150.2 7.7e-36 XP_011513180 (OMIM: 602246) PREDICTED: zinc finger ( 526) 1063 150.3 9.4e-36 XP_011513319 (OMIM: 603978) PREDICTED: zinc finger ( 565) 1039 147.2 8.4e-35 NP_666019 (OMIM: 601261) zinc finger and SCAN doma ( 473) 894 128.4 3.3e-29 XP_005250625 (OMIM: 601261) PREDICTED: zinc finger ( 473) 894 128.4 3.3e-29 XP_016868073 (OMIM: 601261) PREDICTED: zinc finger ( 473) 894 128.4 3.3e-29 XP_006716176 (OMIM: 601261) PREDICTED: zinc finger ( 473) 894 128.4 3.3e-29 NP_001307884 (OMIM: 616463) zinc finger protein 23 ( 416) 891 128.0 3.9e-29 XP_016880511 (OMIM: 616463) PREDICTED: zinc finger ( 368) 882 126.8 8.1e-29 XP_016881178 (OMIM: 609600) PREDICTED: zinc finger ( 266) 726 106.4 7.6e-23 NP_001309220 (OMIM: 609600) zinc finger protein 39 ( 210) 675 99.7 6.2e-21 NP_001230172 (OMIM: 610794) zinc finger and SCAN d ( 247) 641 95.4 1.5e-19 NP_001230173 (OMIM: 610794) zinc finger and SCAN d ( 247) 641 95.4 1.5e-19 NP_001230171 (OMIM: 610794) zinc finger and SCAN d ( 247) 641 95.4 1.5e-19 XP_006715281 (OMIM: 612791) PREDICTED: zinc finger ( 390) 633 94.6 4.1e-19 NP_001229824 (OMIM: 612791) zinc finger protein wi ( 390) 633 94.6 4.1e-19 XP_005249480 (OMIM: 612791) PREDICTED: zinc finger ( 405) 633 94.6 4.2e-19 XP_016866809 (OMIM: 612791) PREDICTED: zinc finger ( 509) 633 94.7 4.9e-19 XP_006715279 (OMIM: 612791) PREDICTED: zinc finger ( 509) 633 94.7 4.9e-19 NP_001229823 (OMIM: 612791) zinc finger protein wi ( 538) 633 94.8 5e-19 XP_006715278 (OMIM: 612791) PREDICTED: zinc finger ( 538) 633 94.8 5e-19 NP_077819 (OMIM: 612791) zinc finger protein with ( 538) 633 94.8 5e-19 XP_011512891 (OMIM: 611643) PREDICTED: zinc finger ( 390) 595 89.7 1.2e-17 XP_016866333 (OMIM: 611643) PREDICTED: zinc finger ( 390) 595 89.7 1.2e-17 NP_001291435 (OMIM: 611643) zinc finger protein wi ( 390) 595 89.7 1.2e-17 >>NP_008896 (OMIM: 194534) zinc finger protein 24 isofor (368 aa) initn: 2534 init1: 2534 opt: 2534 Z-score: 1791.9 bits: 340.2 E(85289): 4.5e-93 Smith-Waterman score: 2534; 99.7% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 WELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLSMGVPQIFKYGETCFPKGRFE :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_008 WELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLNMGVPQIFKYGETCFPKGRFE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 HTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAE 310 320 330 340 350 360 pF1KB7 KLLNVVKV :::::::: NP_008 KLLNVVKV >>XP_005258398 (OMIM: 194534) PREDICTED: zinc finger pro (368 aa) initn: 2534 init1: 2534 opt: 2534 Z-score: 1791.9 bits: 340.2 E(85289): 4.5e-93 Smith-Waterman score: 2534; 99.7% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 WELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLSMGVPQIFKYGETCFPKGRFE :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: XP_005 WELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLNMGVPQIFKYGETCFPKGRFE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAE 310 320 330 340 350 360 pF1KB7 KLLNVVKV :::::::: XP_005 KLLNVVKV >>NP_001295052 (OMIM: 194534) zinc finger protein 24 iso (193 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 920.4 bits: 178.0 E(85289): 1.6e-44 Smith-Waterman score: 1281; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 WELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLSMGVPQIFKYGETCFPKGRFE ::::::::: NP_001 WELHSLRHCVIIP 190 >>NP_001309215 (OMIM: 609600) zinc finger protein 396 is (335 aa) initn: 1106 init1: 925 opt: 1201 Z-score: 861.6 bits: 167.9 E(85289): 3e-41 Smith-Waterman score: 1201; 57.4% identity (77.4% similar) in 340 aa overlap (1-333:1-333) 10 20 30 40 50 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEE-----DPDGEEGSSIPWNHLPDPEIFRQRF :::. . ..: :. : .: . :: :.:: ::: ::. :. .:: :::.: NP_001 MSAK-LGKSSSLLTQTSEECNGILTEKMEEEEQTCDPD----SSLHWSSSYSPETFRQQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDH :::::::::::.::.:.: :::.::::::.:::::::::.:::::.::::::::.::. : NP_001 RQFGYQDSPGPHEALSRLWELCHLWLRPEVHTKEQILELLVLEQFLAILPKELQAWVQKH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 HPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQ :::::::.::.:::.: ::: : : . . ::: ....: .. .: .. ::::.: :..: NP_001 HPENGEETVTMLEDVERELDGPKQ-IFFGRRK-DMIAEKLAPSEITEELPSSQLMPVKKQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LKWASWELHSLRHCDDDGRTENGALAPKQELPSALESH-EVPGTLSMGVPQIFKYGETCF :. :::::.::: :.: .: : : .:. ..: : .: . : :. : : : NP_001 LQGASWELQSLRPHDEDIKTTNVKSASRQKTSLGIELHCNVSNILHMNGSQSSTYRGTYE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 PKGRFERKR-NPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSI ::::... ::: :::. :::::: :::.::::::::::::.:::.: ::.::::::.: NP_001 QDGRFEKRQGNPSWKKQQKCDECGKIFSQSSALILHQRIHSGKKPYACDECAKAFSRSAI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRH :.::.:.::::::::: .:::::::.:.:. :.. : .: NP_001 LIQHRRTHTGEKPYKCHDCGKAFSQSSNLFRHRKRHIRKKVP 300 310 320 330 360 pF1KB7 QRRHNAEKLLNVVKV >>XP_016881177 (OMIM: 609600) PREDICTED: zinc finger pro (335 aa) initn: 1106 init1: 925 opt: 1201 Z-score: 861.6 bits: 167.9 E(85289): 3e-41 Smith-Waterman score: 1201; 57.4% identity (77.4% similar) in 340 aa overlap (1-333:1-333) 10 20 30 40 50 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEE-----DPDGEEGSSIPWNHLPDPEIFRQRF :::. . ..: :. : .: . :: :.:: ::: ::. :. .:: :::.: XP_016 MSAK-LGKSSSLLTQTSEECNGILTEKMEEEEQTCDPD----SSLHWSSSYSPETFRQQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDH :::::::::::.::.:.: :::.::::::.:::::::::.:::::.::::::::.::. : XP_016 RQFGYQDSPGPHEALSRLWELCHLWLRPEVHTKEQILELLVLEQFLAILPKELQAWVQKH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 HPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQ :::::::.::.:::.: ::: : : . . ::: ....: .. .: .. ::::.: :..: XP_016 HPENGEETVTMLEDVERELDGPKQ-IFFGRRK-DMIAEKLAPSEITEELPSSQLMPVKKQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LKWASWELHSLRHCDDDGRTENGALAPKQELPSALESH-EVPGTLSMGVPQIFKYGETCF :. :::::.::: :.: .: : : .:. ..: : .: . : :. : : : XP_016 LQGASWELQSLRPHDEDIKTTNVKSASRQKTSLGIELHCNVSNILHMNGSQSSTYRGTYE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 PKGRFERKR-NPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSI ::::... ::: :::. :::::: :::.::::::::::::.:::.: ::.::::::.: XP_016 QDGRFEKRQGNPSWKKQQKCDECGKIFSQSSALILHQRIHSGKKPYACDECAKAFSRSAI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRH :.::.:.::::::::: .:::::::.:.:. :.. : .: XP_016 LIQHRRTHTGEKPYKCHDCGKAFSQSSNLFRHRKRHIRKKVP 300 310 320 330 360 pF1KB7 QRRHNAEKLLNVVKV >>XP_016881176 (OMIM: 609600) PREDICTED: zinc finger pro (335 aa) initn: 1106 init1: 925 opt: 1201 Z-score: 861.6 bits: 167.9 E(85289): 3e-41 Smith-Waterman score: 1201; 57.4% identity (77.4% similar) in 340 aa overlap (1-333:1-333) 10 20 30 40 50 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEE-----DPDGEEGSSIPWNHLPDPEIFRQRF :::. . ..: :. : .: . :: :.:: ::: ::. :. .:: :::.: XP_016 MSAK-LGKSSSLLTQTSEECNGILTEKMEEEEQTCDPD----SSLHWSSSYSPETFRQQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDH :::::::::::.::.:.: :::.::::::.:::::::::.:::::.::::::::.::. : XP_016 RQFGYQDSPGPHEALSRLWELCHLWLRPEVHTKEQILELLVLEQFLAILPKELQAWVQKH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 HPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQ :::::::.::.:::.: ::: : : . . ::: ....: .. .: .. ::::.: :..: XP_016 HPENGEETVTMLEDVERELDGPKQ-IFFGRRK-DMIAEKLAPSEITEELPSSQLMPVKKQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LKWASWELHSLRHCDDDGRTENGALAPKQELPSALESH-EVPGTLSMGVPQIFKYGETCF :. :::::.::: :.: .: : : .:. ..: : .: . : :. : : : XP_016 LQGASWELQSLRPHDEDIKTTNVKSASRQKTSLGIELHCNVSNILHMNGSQSSTYRGTYE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 PKGRFERKR-NPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSI ::::... ::: :::. :::::: :::.::::::::::::.:::.: ::.::::::.: XP_016 QDGRFEKRQGNPSWKKQQKCDECGKIFSQSSALILHQRIHSGKKPYACDECAKAFSRSAI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRH :.::.:.::::::::: .:::::::.:.:. :.. : .: XP_016 LIQHRRTHTGEKPYKCHDCGKAFSQSSNLFRHRKRHIRKKVP 300 310 320 330 360 pF1KB7 QRRHNAEKLLNVVKV >>NP_001309219 (OMIM: 609600) zinc finger protein 396 is (335 aa) initn: 1106 init1: 925 opt: 1201 Z-score: 861.6 bits: 167.9 E(85289): 3e-41 Smith-Waterman score: 1201; 57.4% identity (77.4% similar) in 340 aa overlap (1-333:1-333) 10 20 30 40 50 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEE-----DPDGEEGSSIPWNHLPDPEIFRQRF :::. . ..: :. : .: . :: :.:: ::: ::. :. .:: :::.: NP_001 MSAK-LGKSSSLLTQTSEECNGILTEKMEEEEQTCDPD----SSLHWSSSYSPETFRQQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDH :::::::::::.::.:.: :::.::::::.:::::::::.:::::.::::::::.::. : NP_001 RQFGYQDSPGPHEALSRLWELCHLWLRPEVHTKEQILELLVLEQFLAILPKELQAWVQKH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 HPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQ :::::::.::.:::.: ::: : : . . ::: ....: .. .: .. ::::.: :..: NP_001 HPENGEETVTMLEDVERELDGPKQ-IFFGRRK-DMIAEKLAPSEITEELPSSQLMPVKKQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LKWASWELHSLRHCDDDGRTENGALAPKQELPSALESH-EVPGTLSMGVPQIFKYGETCF :. :::::.::: :.: .: : : .:. ..: : .: . : :. : : : NP_001 LQGASWELQSLRPHDEDIKTTNVKSASRQKTSLGIELHCNVSNILHMNGSQSSTYRGTYE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 PKGRFERKR-NPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSI ::::... ::: :::. :::::: :::.::::::::::::.:::.: ::.::::::.: NP_001 QDGRFEKRQGNPSWKKQQKCDECGKIFSQSSALILHQRIHSGKKPYACDECAKAFSRSAI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRH :.::.:.::::::::: .:::::::.:.:. :.. : .: NP_001 LIQHRRTHTGEKPYKCHDCGKAFSQSSNLFRHRKRHIRKKVP 300 310 320 330 360 pF1KB7 QRRHNAEKLLNVVKV >>XP_006722495 (OMIM: 609600) PREDICTED: zinc finger pro (335 aa) initn: 1106 init1: 925 opt: 1201 Z-score: 861.6 bits: 167.9 E(85289): 3e-41 Smith-Waterman score: 1201; 57.4% identity (77.4% similar) in 340 aa overlap (1-333:1-333) 10 20 30 40 50 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILRVKLEE-----DPDGEEGSSIPWNHLPDPEIFRQRF :::. . ..: :. : .: . :: :.:: ::: ::. :. .:: :::.: XP_006 MSAK-LGKSSSLLTQTSEECNGILTEKMEEEEQTCDPD----SSLHWSSSYSPETFRQQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 RQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDH :::::::::::.::.:.: :::.::::::.:::::::::.:::::.::::::::.::. : XP_006 RQFGYQDSPGPHEALSRLWELCHLWLRPEVHTKEQILELLVLEQFLAILPKELQAWVQKH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 HPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQ :::::::.::.:::.: ::: : : . . ::: ....: .. .: .. ::::.: :..: XP_006 HPENGEETVTMLEDVERELDGPKQ-IFFGRRK-DMIAEKLAPSEITEELPSSQLMPVKKQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LKWASWELHSLRHCDDDGRTENGALAPKQELPSALESH-EVPGTLSMGVPQIFKYGETCF :. :::::.::: :.: .: : : .:. ..: : .: . : :. : : : XP_006 LQGASWELQSLRPHDEDIKTTNVKSASRQKTSLGIELHCNVSNILHMNGSQSSTYRGTYE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 PKGRFERKR-NPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSI ::::... ::: :::. :::::: :::.::::::::::::.:::.: ::.::::::.: XP_006 QDGRFEKRQGNPSWKKQQKCDECGKIFSQSSALILHQRIHSGKKPYACDECAKAFSRSAI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRH :.::.:.::::::::: .:::::::.:.:. :.. : .: XP_006 LIQHRRTHTGEKPYKCHDCGKAFSQSSNLFRHRKRHIRKKVP 300 310 320 330 360 pF1KB7 QRRHNAEKLLNVVKV >>NP_001128688 (OMIM: 610794) zinc finger and SCAN domai (406 aa) initn: 1088 init1: 590 opt: 1164 Z-score: 834.8 bits: 163.2 E(85289): 9.3e-40 Smith-Waterman score: 1164; 53.0% identity (76.1% similar) in 347 aa overlap (19-361:5-349) 10 20 30 40 50 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILR-VKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFG ::. :. ::.:::: .. . . :.. : :: :::: NP_001 MASTEEQYDLKIVKVEEDPIWDQETHLRGNNFSGQEASRQLFRQFC 10 20 30 40 60 70 80 90 100 110 pF1KB7 YQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPEN ::..::::::.:.:::::. ::::: :::::::::.:::::..:::.:::.:::.::::. NP_001 YQETPGPREALSRLRELCHQWLRPEIHTKEQILELLVLEQFLTILPEELQAWVREHHPES 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 GEEAVTVLEDLESELDDPG-QPVSLRRRKREVLVEDMVSQEEAQGLPSS-ELDAVENQLK :::::.:.::::.::..:: : . .. . :::.:: : . ... :.. .:. . .::. NP_001 GEEAVAVVEDLEQELSEPGNQAPDHEHGHSEVLLED-VEHLKVKQEPTDIQLQPMVTQLR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 WASWELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLSMGVPQIFKYGETCFPKG . :. ::.... : .. :: :: :::. . .: : . :. : :: ::: . NP_001 YESFCLHQFQEQDGESIPENQELASKQEILKEME-HLGDSKLQRDVSLDSKYRETCKRDS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 RFERKRNPSR-KKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQ . :... : ...: :.:::: :...:.:: :::::.::::: : :::::::: : : . NP_001 KAEKQQAHSTGERRHRCNECGKSFTKSSVLIEHQRIHTGEKPYECEECGKAFSRRSSLNE 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 HQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRR :.: :::::::.: ::::::: ..:: :.::::::::::: :::.. :: : .::: NP_001 HRRSHTGEKPYQCKECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLSSCLVQHQRI 290 300 310 320 330 340 360 pF1KB7 HNAEKLLNVVKV :..:: NP_001 HTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLKKHQKIHTGE 350 360 370 380 390 400 >-- initn: 473 init1: 238 opt: 254 Z-score: 199.4 bits: 45.7 E(85289): 0.00023 Smith-Waterman score: 254; 60.7% identity (80.4% similar) in 56 aa overlap (279-334:351-406) 250 260 270 280 290 300 pF1KB7 KQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYK : : :::::: ... : :: :::::::::. NP_001 KPYECKVCGKAFLLSSCLVQHQRIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQ 330 340 350 360 370 380 310 320 330 340 350 360 pF1KB7 CLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEKLLNVVKV : .:.: ::. . : .::.:::::.: NP_001 CSQCSKLFSKRTLLKKHQKIHTGERP 390 400 >>XP_016866685 (OMIM: 610794) PREDICTED: zinc finger and (406 aa) initn: 1088 init1: 590 opt: 1164 Z-score: 834.8 bits: 163.2 E(85289): 9.3e-40 Smith-Waterman score: 1164; 53.0% identity (76.1% similar) in 347 aa overlap (19-361:5-349) 10 20 30 40 50 pF1KB7 MSAQSVEEDSILIIPTPDEEEKILR-VKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFG ::. :. ::.:::: .. . . :.. : :: :::: XP_016 MASTEEQYDLKIVKVEEDPIWDQETHLRGNNFSGQEASRQLFRQFC 10 20 30 40 60 70 80 90 100 110 pF1KB7 YQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPEN ::..::::::.:.:::::. ::::: :::::::::.:::::..:::.:::.:::.::::. XP_016 YQETPGPREALSRLRELCHQWLRPEIHTKEQILELLVLEQFLTILPEELQAWVREHHPES 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 GEEAVTVLEDLESELDDPG-QPVSLRRRKREVLVEDMVSQEEAQGLPSS-ELDAVENQLK :::::.:.::::.::..:: : . .. . :::.:: : . ... :.. .:. . .::. XP_016 GEEAVAVVEDLEQELSEPGNQAPDHEHGHSEVLLED-VEHLKVKQEPTDIQLQPMVTQLR 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 WASWELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLSMGVPQIFKYGETCFPKG . :. ::.... : .. :: :: :::. . .: : . :. : :: ::: . XP_016 YESFCLHQFQEQDGESIPENQELASKQEILKEME-HLGDSKLQRDVSLDSKYRETCKRDS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 RFERKRNPSR-KKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQ . :... : ...: :.:::: :...:.:: :::::.::::: : :::::::: : : . XP_016 KAEKQQAHSTGERRHRCNECGKSFTKSSVLIEHQRIHTGEKPYECEECGKAFSRRSSLNE 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 HQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRR :.: :::::::.: ::::::: ..:: :.::::::::::: :::.. :: : .::: XP_016 HRRSHTGEKPYQCKECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLSSCLVQHQRI 290 300 310 320 330 340 360 pF1KB7 HNAEKLLNVVKV :..:: XP_016 HTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLKKHQKIHTGE 350 360 370 380 390 400 >-- initn: 473 init1: 238 opt: 254 Z-score: 199.4 bits: 45.7 E(85289): 0.00023 Smith-Waterman score: 254; 60.7% identity (80.4% similar) in 56 aa overlap (279-334:351-406) 250 260 270 280 290 300 pF1KB7 KQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYK : : :::::: ... : :: :::::::::. XP_016 KPYECKVCGKAFLLSSCLVQHQRIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQ 330 340 350 360 370 380 310 320 330 340 350 360 pF1KB7 CLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEKLLNVVKV : .:.: ::. . : .::.:::::.: XP_016 CSQCSKLFSKRTLLKKHQKIHTGERP 390 400 368 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:19:25 2016 done: Sat Nov 5 04:19:27 2016 Total Scan time: 8.790 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]