FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7629, 319 aa 1>>>pF1KB7629 319 - 319 aa - 319 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6613+/-0.00111; mu= 4.8912+/- 0.066 mean_var=162.2770+/-32.946, 0's: 0 Z-trim(107.0): 234 B-trim: 0 in 0/55 Lambda= 0.100681 statistics sampled from 9028 (9291) to 9028 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.285), width: 16 Scan time: 2.690 The best scores are: opt bits E(32554) CCDS7412.1 ANKRD1 gene_id:27063|Hs108|chr10 ( 319) 2070 312.8 2.2e-85 CCDS7466.1 ANKRD2 gene_id:26287|Hs108|chr10 ( 360) 846 135.1 8.2e-32 CCDS2027.1 ANKRD23 gene_id:200539|Hs108|chr2 ( 305) 773 124.4 1.1e-28 CCDS44468.1 ANKRD2 gene_id:26287|Hs108|chr10 ( 327) 571 95.1 8e-20 >>CCDS7412.1 ANKRD1 gene_id:27063|Hs108|chr10 (319 aa) initn: 2070 init1: 2070 opt: 2070 Z-score: 1646.2 bits: 312.8 E(32554): 2.2e-85 Smith-Waterman score: 2070; 100.0% identity (100.0% similar) in 319 aa overlap (1-319:1-319) 10 20 30 40 50 60 pF1KB7 MMVLKVEELVTGKKNGNGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MMVLKVEELVTGKKNGNGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEIITEPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEIITEPVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 FRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 CEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHWQNGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 CEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHWQNGTK 250 260 270 280 290 300 310 pF1KB7 AIFDSLRENSYKTSRIATF ::::::::::::::::::: CCDS74 AIFDSLRENSYKTSRIATF 310 >>CCDS7466.1 ANKRD2 gene_id:26287|Hs108|chr10 (360 aa) initn: 1119 init1: 800 opt: 846 Z-score: 684.6 bits: 135.1 E(32554): 8.2e-32 Smith-Waterman score: 846; 48.4% identity (75.1% similar) in 285 aa overlap (20-300:50-328) 10 20 30 40 pF1KB7 MMVLKVEELVTGKKNGNGEAGEFLPEDFR-DGEYEAAVTLEKQEDLKTL : : : .: :.. . . : :: : CCDS74 ALWPAEAVMDGTMEDSEAVQRATALIEQRLAQEEENEKLRGDARQKLPMDLLVLEDEKHH 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB7 LAHPVTLGEQQWKSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKTKVPVVK :. ..: :. :.... ..: .:. : .. .. .. .:.:.:..: .: . ... CCDS74 GAQSAAL--QKVKGQER----VRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAS 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB7 E---PEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGH . :::: :: ::: ::::::.:.:. :.::::.: .. :.::...::::::: :::: CCDS74 HEPPPEPEEITGPVDEETFLKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGH 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB7 LAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHV . :.:::.. :: ..:.: :. ::.::: :::.:.:.::: ..:: ..::::::: ::: CCDS74 MEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHV 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB7 AVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAG :::::. : .::... ..::.:::::: :::::::::::.:.::...:::. :: :: CCDS74 AVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAG 260 270 280 290 300 310 290 300 310 pF1KB7 KTPMDLVLHWQNGTKAIFDSLRENSYKTSRIATF ::: ::: :: :. CCDS74 KTPTDLVQLWQADTRHALEHPEPGAEHNGLEGPNDSGRETPQPVPAQ 320 330 340 350 360 >>CCDS2027.1 ANKRD23 gene_id:200539|Hs108|chr2 (305 aa) initn: 1168 init1: 678 opt: 773 Z-score: 628.3 bits: 124.4 E(32554): 1.1e-28 Smith-Waterman score: 773; 49.6% identity (73.8% similar) in 248 aa overlap (63-300:47-291) 40 50 60 70 80 pF1KB7 YEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELKKKKLEQ----RSKLENLEDLE :: . : ::::::. : .:.:: ::: CCDS20 GKVLGFGHGVPDPGAWPSDWRRGPQEAVAREKLKLEEEKKKKLERFNSTRFNLDNLADLE 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB7 IIIQLKKRKKYRKTKVPVVKEPEPEII------TEPVDVPTFLKAALENKLPVVEKFLSD ..: .::: . .:: ..::: . .::: . ::::: ::. ...:.:.: CCDS20 NLVQ--RRKKRLRHRVPP-RKPEPLVKPQSQAQVEPVGLEMFLKAAAENQEYLIDKYLTD 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB7 KNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVL ..:.. :. .::::: :::.:: .:.::. ::: .. ::.:. : . :: :::.: .: CCDS20 GGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVIL 140 150 160 170 180 190 210 220 230 240 250 260 pF1KB7 KLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRL : :::.::...::::. :: ::::::: : .: :::: : : :::.:.:::: ::.::: CCDS20 KQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRH 200 210 220 230 240 250 270 280 290 300 310 pF1KB7 NRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHWQNGTKAIFDSLRENSYKTSRIATF . :: ..::..:::.:...: :. ::..:. :: : . CCDS20 GSYKAMKLLLLYGAELGVRNAASVTPVQLARDWQRGIREALQAHVAHPRTRC 260 270 280 290 300 >>CCDS44468.1 ANKRD2 gene_id:26287|Hs108|chr10 (327 aa) initn: 947 init1: 521 opt: 571 Z-score: 469.4 bits: 95.1 E(32554): 8e-20 Smith-Waterman score: 658; 41.8% identity (66.0% similar) in 285 aa overlap (20-300:50-295) 10 20 30 40 pF1KB7 MMVLKVEELVTGKKNGNGEAGEFLPEDFR-DGEYEAAVTLEKQEDLKTL : : : .: :.. . . : :: : CCDS44 ALWPAEAVMDGTMEDSEAVQRATALIEQRLAQEEENEKLRGDARQKLPMDLLVLEDEKHH 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB7 LAHPVTLGEQQWKSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKTKVPVVK :. ..: :. :.... ..: .:. : .. .. .. .:.:.:..: .: . ... CCDS44 GAQSAAL--QKVKGQER----VRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAS 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB7 E---PEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGH . :::: :: ::: ::::::.:.:. :.::::.: .. :.::...::::::: :::: CCDS44 HEPPPEPEEITGPVDEETFLKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGH 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB7 LAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHV . :.:::.. :: ..:.: :. ::.::: :::.:.:.::: ..:: CCDS44 MEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGA--------------- 200 210 220 230 230 240 250 260 270 280 pF1KB7 AVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAG : :..:.:::: :::::::::::.:.::...:::. :: :: CCDS44 ------------------DTNVRDKEGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAG 240 250 260 270 280 290 300 310 pF1KB7 KTPMDLVLHWQNGTKAIFDSLRENSYKTSRIATF ::: ::: :: :. CCDS44 KTPTDLVQLWQADTRHALEHPEPGAEHNGLEGPNDSGRETPQPVPAQ 290 300 310 320 319 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:08:07 2016 done: Sat Nov 5 18:08:07 2016 Total Scan time: 2.690 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]