FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7631, 320 aa 1>>>pF1KB7631 320 - 320 aa - 320 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4774+/-0.000773; mu= 8.6106+/- 0.047 mean_var=177.3390+/-35.361, 0's: 0 Z-trim(115.9): 28 B-trim: 723 in 1/52 Lambda= 0.096310 statistics sampled from 16418 (16446) to 16418 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.818), E-opt: 0.2 (0.505), width: 16 Scan time: 2.990 The best scores are: opt bits E(32554) CCDS7826.1 MYOD1 gene_id:4654|Hs108|chr11 ( 320) 2225 320.4 1.2e-87 CCDS9020.1 MYF5 gene_id:4617|Hs108|chr12 ( 255) 564 89.5 2.9e-18 CCDS1433.1 MYOG gene_id:4656|Hs108|chr1 ( 224) 422 69.8 2.3e-12 CCDS9019.1 MYF6 gene_id:4618|Hs108|chr12 ( 242) 420 69.5 3e-12 >>CCDS7826.1 MYOD1 gene_id:4654|Hs108|chr11 (320 aa) initn: 2225 init1: 2225 opt: 2225 Z-score: 1687.3 bits: 320.4 E(32554): 1.2e-87 Smith-Waterman score: 2225; 100.0% identity (100.0% similar) in 320 aa overlap (1-320:1-320) 10 20 30 40 50 60 pF1KB7 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 GKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQS 250 260 270 280 290 300 310 320 pF1KB7 PDAAPQCPAGANPNPIYQVL :::::::::::::::::::: CCDS78 PDAAPQCPAGANPNPIYQVL 310 320 >>CCDS9020.1 MYF5 gene_id:4617|Hs108|chr12 (255 aa) initn: 758 init1: 550 opt: 564 Z-score: 441.3 bits: 89.5 E(32554): 2.9e-18 Smith-Waterman score: 767; 48.7% identity (69.2% similar) in 279 aa overlap (17-294:5-247) 10 20 30 40 50 60 pF1KB7 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE :: :.:. .. ::: :. ::. .: ... ::. :: CCDS90 MDVMDG--CQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGA----- 10 20 30 40 70 80 90 100 110 120 pF1KB7 EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR :. : .. :. ::::::::.::::::.::.:::::::::.:. :::::::::::: CCDS90 -HK---AELQ---GSDEDEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERR 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA ::.:::.:::::::::..::::::::::::::::::::.:: :::.: . .:. CCDS90 RLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQ-------VENYYS 100 110 120 130 140 190 200 210 220 230 240 pF1KB7 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP ::.. :. .:: ::::::: . ..: .:. . ... : .. . CCDS90 L----PGQSC------SEPTSPTSNCSDGMPECNSP-VWSRKSSTFDSIYCPDVSNVYAT 150 160 170 180 190 250 260 270 280 290 pF1KB7 GKSAAVSSLDCLSSIVERI-STESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQ :.. .:::::::.::.:: :.:.:. : : :. : :: .. . : :: CCDS90 DKNS-LSSLDCLSNIVDRITSSEQPGLP---LQDLASLSPVASTDSQPATPGASSSRLIY 200 210 220 230 240 250 300 310 320 pF1KB7 SPDAAPQCPAGANPNPIYQVL CCDS90 HVL >>CCDS1433.1 MYOG gene_id:4656|Hs108|chr1 (224 aa) initn: 444 init1: 382 opt: 422 Z-score: 335.4 bits: 69.8 E(32554): 2.3e-12 Smith-Waterman score: 434; 41.7% identity (64.3% similar) in 199 aa overlap (23-217:4-183) 10 20 30 40 50 60 pF1KB7 MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE . :. ::..: ::.. . .:. .. .: CCDS14 MELYETSPYFYQEP-------RFYDGENYLPVHLQGF-EPP 10 20 30 70 80 90 100 110 pF1KB7 EHSHFPAAVHP-APGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRER . . .. : ::: ::. . .: .: :.:: ::::.::::....:::.:::.::. CCDS14 GYERTELTLSPEAPGPLEDKGLGTP--EHCPGQCLPWACKVCKRKSVSVDRRRAATLREK 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 RRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFY :::.:::::::.::: : :::::::::::::.::.::: ::::: . . : CCDS14 RRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLR---Y 100 110 120 130 140 180 190 200 210 220 230 pF1KB7 APGPLPPGRGGEHYSGDSDASSPRSNCSD---GMMDYSGPPSGARRRNCYEGAYYNEAPS : :: . . :. :: ..:: . ...:. : CCDS14 RGG------GGPQPGVPSECSSHSASCSPEWGSALEFSANPGDHLLTADPTDAHNLHSLT 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB7 EPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGD CCDS14 SIVDSITVEDVSVAFPDETMPN 210 220 >>CCDS9019.1 MYF6 gene_id:4618|Hs108|chr12 (242 aa) initn: 472 init1: 388 opt: 420 Z-score: 333.4 bits: 69.5 E(32554): 3e-12 Smith-Waterman score: 446; 44.9% identity (58.4% similar) in 214 aa overlap (57-267:41-234) 30 40 50 60 70 80 pF1KB7 DDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPEEHSHFPAAVHPAPGAREDEHVRAPSG :.: . . : : . : .::: :: : CCDS90 YFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSG---EEHVLAPPG 20 30 40 50 60 90 100 110 120 130 140 pF1KB7 ---HHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQR : :.::.::::.::::.. .:::::::.::::::.:.:::::.::: : .::::: CCDS90 LQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQR 70 80 90 100 110 120 150 160 170 180 190 200 pF1KB7 LPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDASSPR ::::::::.:: ::: :: ::. : . : : . :. : :. : CCDS90 LPKVEILRSAISYIERLQDLLHRLDQQEKMQELGV-DPFSYRPKQ--ENLEG---ADFLR 130 140 150 160 170 180 210 220 230 240 250 260 pF1KB7 SNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRPGKSAAVSSLDCLSSIVERISTES . ::. . : : :: . :.: ::: ::::::. ::.: CCDS90 T-CSSQWPSVSDHSRGLVITAKEGGASID----------SSASSSLRCLSSIVDSISSEE 190 200 210 220 230 270 280 290 300 310 320 pF1KB7 PAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQSPDAAPQCPAGANPNPIYQVL : CCDS90 RKLPCVEEVVEK 240 320 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:04:18 2016 done: Fri Nov 4 09:04:19 2016 Total Scan time: 2.990 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]