FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7632, 364 aa 1>>>pF1KB7632 364 - 364 aa - 364 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6548+/-0.000293; mu= 2.9418+/- 0.018 mean_var=189.4541+/-36.794, 0's: 0 Z-trim(124.1): 4 B-trim: 0 in 0/57 Lambda= 0.093180 statistics sampled from 45038 (45043) to 45038 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.528), width: 16 Scan time: 8.950 The best scores are: opt bits E(85289) NP_005988 (OMIM: 600607) vacuolar protein sorting- ( 364) 2459 342.1 1.2e-93 NP_001258016 (OMIM: 600607) vacuolar protein sorti ( 375) 1557 220.8 3.9e-57 NP_001258017 (OMIM: 600607) vacuolar protein sorti ( 199) 1246 178.8 9e-45 XP_016857694 (OMIM: 600607) PREDICTED: vacuolar pr ( 243) 904 132.9 7.3e-31 >>NP_005988 (OMIM: 600607) vacuolar protein sorting-asso (364 aa) initn: 2459 init1: 2459 opt: 2459 Z-score: 1802.3 bits: 342.1 E(85289): 1.2e-93 Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KB7 MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 YRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQK 310 320 330 340 350 360 pF1KB7 IVIK :::: NP_005 IVIK >>NP_001258016 (OMIM: 600607) vacuolar protein sorting-a (375 aa) initn: 2445 init1: 1555 opt: 1557 Z-score: 1146.8 bits: 220.8 E(85289): 3.9e-57 Smith-Waterman score: 2427; 97.1% identity (97.1% similar) in 375 aa overlap (1-364:1-375) 10 20 30 40 50 60 pF1KB7 MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGSLCF 190 200 210 220 230 240 240 250 260 270 280 pF1KB7 -------LDPAPSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVR ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSFVLRLDPAPSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVR 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 EVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPL 310 320 330 340 350 360 350 360 pF1KB7 PGSGPRALRQKIVIK ::::::::::::::: NP_001 PGSGPRALRQKIVIK 370 >>NP_001258017 (OMIM: 600607) vacuolar protein sorting-a (199 aa) initn: 1246 init1: 1246 opt: 1246 Z-score: 924.8 bits: 178.8 E(85289): 9e-45 Smith-Waterman score: 1246; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB7 MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPA ::::::::::: NP_001 ELNLRSLETYEAAPKSPCS 190 >>XP_016857694 (OMIM: 600607) PREDICTED: vacuolar protei (243 aa) initn: 1582 init1: 904 opt: 904 Z-score: 675.1 bits: 132.9 E(85289): 7.3e-31 Smith-Waterman score: 1564; 95.5% identity (95.5% similar) in 243 aa overlap (133-364:1-243) 110 120 130 140 150 160 pF1KB7 TPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPH :::::::::::::::::::::::::::::: XP_016 MRQSTAEHTRQTFLRVQERQGQSRRRKGPH 10 20 30 170 180 190 200 210 220 pF1KB7 CERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLV 40 50 60 70 80 90 230 240 250 260 270 pF1KB7 GEPGPKEENVDIEG-----------LDPAPSVSALTPHAGTGPVNPPARCSRTFITFSDD :::::::::::::: ::::::::::::::::::::::::::::::::::: XP_016 GEPGPKEENVDIEGSLCFSLSFVLRLDPAPSVSALTPHAGTGPVNPPARCSRTFITFSDD 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB7 ATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHG 160 170 180 190 200 210 340 350 360 pF1KB7 LPPTASALGPGPPPPEPLPGSGPRALRQKIVIK ::::::::::::::::::::::::::::::::: XP_016 LPPTASALGPGPPPPEPLPGSGPRALRQKIVIK 220 230 240 364 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:04:55 2016 done: Fri Nov 4 09:04:56 2016 Total Scan time: 8.950 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]