FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7636, 377 aa 1>>>pF1KB7636 377 - 377 aa - 377 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1595+/-0.000371; mu= 16.8656+/- 0.023 mean_var=58.2981+/-12.329, 0's: 0 Z-trim(111.9): 108 B-trim: 898 in 1/56 Lambda= 0.167976 statistics sampled from 20565 (20675) to 20565 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.242), width: 16 Scan time: 6.740 The best scores are: opt bits E(85289) NP_060956 (OMIM: 300269) histone deacetylase 8 iso ( 377) 2575 632.5 4.8e-181 XP_011529288 (OMIM: 300269) PREDICTED: histone dea ( 441) 2529 621.4 1.2e-177 XP_011529289 (OMIM: 300269) PREDICTED: histone dea ( 379) 2280 561.0 1.6e-159 NP_001159891 (OMIM: 300269) histone deacetylase 8 ( 256) 1674 414.1 1.8e-115 XP_016885135 (OMIM: 300269) PREDICTED: histone dea ( 274) 1666 412.2 7.4e-115 NP_001159890 (OMIM: 300269) histone deacetylase 8 ( 286) 1586 392.8 5.3e-109 XP_016885131 (OMIM: 300269) PREDICTED: histone dea ( 350) 1540 381.7 1.4e-105 XP_016885136 (OMIM: 300269) PREDICTED: histone dea ( 268) 1264 314.7 1.5e-85 XP_016885130 (OMIM: 300269) PREDICTED: histone dea ( 389) 1264 314.8 2.1e-85 XP_016885129 (OMIM: 300269) PREDICTED: histone dea ( 415) 1264 314.8 2.3e-85 XP_016885133 (OMIM: 300269) PREDICTED: histone dea ( 324) 1104 276.0 8.6e-74 XP_011534090 (OMIM: 605164) PREDICTED: histone dea ( 458) 1089 272.4 1.4e-72 XP_016866288 (OMIM: 605164) PREDICTED: histone dea ( 458) 1089 272.4 1.4e-72 NP_001518 (OMIM: 605164) histone deacetylase 2 [Ho ( 488) 1089 272.4 1.5e-72 NP_004955 (OMIM: 601241) histone deacetylase 1 [Ho ( 482) 1083 271.0 4.1e-72 NP_003874 (OMIM: 605166) histone deacetylase 3 [Ho ( 428) 1048 262.5 1.3e-69 NP_001159894 (OMIM: 300269) histone deacetylase 8 ( 158) 1001 250.9 1.5e-66 NP_001159892 (OMIM: 300269) histone deacetylase 8 ( 146) 999 250.4 2e-66 XP_016885134 (OMIM: 300269) PREDICTED: histone dea ( 315) 993 249.1 1e-65 XP_016885132 (OMIM: 300269) PREDICTED: histone dea ( 341) 993 249.1 1.1e-65 XP_011539611 (OMIM: 601241) PREDICTED: histone dea ( 289) 576 148.0 2.6e-35 XP_011535999 (OMIM: 605166) PREDICTED: histone dea ( 241) 521 134.7 2.2e-31 NP_001308157 (OMIM: 300272,300863) histone deacety (1215) 400 105.6 6.1e-22 NP_001308156 (OMIM: 300272,300863) histone deacety (1215) 400 105.6 6.1e-22 NP_001308155 (OMIM: 300272,300863) histone deacety (1215) 400 105.6 6.1e-22 NP_006035 (OMIM: 300272,300863) histone deacetylas (1215) 400 105.6 6.1e-22 NP_001308158 (OMIM: 300272,300863) histone deacety (1215) 400 105.6 6.1e-22 NP_001308154 (OMIM: 300272,300863) histone deacety (1229) 400 105.7 6.2e-22 NP_001159920 (OMIM: 300269) histone deacetylase 8 ( 139) 364 96.5 4e-20 XP_016884676 (OMIM: 300272,300863) PREDICTED: hist ( 622) 364 96.8 1.5e-19 NP_478056 (OMIM: 606543) histone deacetylase 9 iso (1011) 360 95.9 4.3e-19 NP_001308826 (OMIM: 606543) histone deacetylase 9 (1025) 360 95.9 4.4e-19 XP_016868317 (OMIM: 606543) PREDICTED: histone dea (1025) 360 95.9 4.4e-19 NP_001308806 (OMIM: 606543) histone deacetylase 9 (1025) 360 95.9 4.4e-19 XP_011513948 (OMIM: 606543) PREDICTED: histone dea (1035) 360 95.9 4.4e-19 XP_011513947 (OMIM: 606543) PREDICTED: histone dea (1038) 360 95.9 4.4e-19 XP_011513946 (OMIM: 606543) PREDICTED: histone dea (1038) 360 95.9 4.4e-19 XP_011513944 (OMIM: 606543) PREDICTED: histone dea (1043) 360 95.9 4.5e-19 XP_016868316 (OMIM: 606543) PREDICTED: histone dea (1043) 360 95.9 4.5e-19 XP_011513943 (OMIM: 606543) PREDICTED: histone dea (1043) 360 95.9 4.5e-19 XP_011513936 (OMIM: 606543) PREDICTED: histone dea (1044) 360 95.9 4.5e-19 NP_001308797 (OMIM: 606543) histone deacetylase 9 (1044) 360 95.9 4.5e-19 XP_016868315 (OMIM: 606543) PREDICTED: histone dea (1066) 360 95.9 4.5e-19 NP_848510 (OMIM: 606543) histone deacetylase 9 iso (1066) 360 95.9 4.5e-19 XP_011513940 (OMIM: 606543) PREDICTED: histone dea (1069) 360 95.9 4.5e-19 NP_848512 (OMIM: 606543) histone deacetylase 9 iso (1069) 360 95.9 4.5e-19 XP_011513941 (OMIM: 606543) PREDICTED: histone dea (1069) 360 95.9 4.5e-19 XP_011513938 (OMIM: 606543) PREDICTED: histone dea (1071) 360 95.9 4.6e-19 XP_011513939 (OMIM: 606543) PREDICTED: histone dea (1071) 360 95.9 4.6e-19 XP_011513950 (OMIM: 606543) PREDICTED: histone dea (1074) 360 95.9 4.6e-19 >>NP_060956 (OMIM: 300269) histone deacetylase 8 isoform (377 aa) initn: 2575 init1: 2575 opt: 2575 Z-score: 3371.4 bits: 632.5 E(85289): 4.8e-181 Smith-Waterman score: 2575; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH 310 320 330 340 350 360 370 pF1KB7 RIQQILNYIKGNLKHVV ::::::::::::::::: NP_060 RIQQILNYIKGNLKHVV 370 >>XP_011529288 (OMIM: 300269) PREDICTED: histone deacety (441 aa) initn: 2553 init1: 2529 opt: 2529 Z-score: 3310.1 bits: 621.4 E(85289): 1.2e-177 Smith-Waterman score: 2529; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:39-408) 10 20 30 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDS :::::::::::::::::::::::::::::: XP_011 GRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE 310 320 330 340 350 360 340 350 360 370 pF1KB7 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV :::::::::::::::::::::::::::::::::::::::: XP_011 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKA 370 380 390 400 410 420 XP_011 KTTEGQRNLKHVV 430 440 >>XP_011529289 (OMIM: 300269) PREDICTED: histone deacety (379 aa) initn: 2280 init1: 2280 opt: 2280 Z-score: 2985.0 bits: 561.0 E(85289): 1.6e-159 Smith-Waterman score: 2280; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:39-373) 10 20 30 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDS :::::::::::::::::::::::::::::: XP_011 GRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE 310 320 330 340 350 360 340 350 360 370 pF1KB7 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV ::::: XP_011 IPDHENMPVNT 370 >>NP_001159891 (OMIM: 300269) histone deacetylase 8 isof (256 aa) initn: 1674 init1: 1674 opt: 1674 Z-score: 2193.9 bits: 414.1 E(85289): 1.8e-115 Smith-Waterman score: 1674; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI ::::: NP_001 YQICERYEPPAPNPGL 250 >>XP_016885135 (OMIM: 300269) PREDICTED: histone deacety (274 aa) initn: 1690 init1: 1666 opt: 1666 Z-score: 2183.0 bits: 412.2 E(85289): 7.4e-115 Smith-Waterman score: 1666; 100.0% identity (100.0% similar) in 241 aa overlap (130-370:1-241) 100 110 120 130 140 150 pF1KB7 YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAV :::::::::::::::::::::::::::::: XP_016 MCKVAINWSGGWHHAKKDEASGFCYLNDAV 10 20 30 160 170 180 190 200 210 pF1KB7 LGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGL 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB7 GKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNM 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB7 TPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTA 160 170 180 190 200 210 340 350 360 370 pF1KB7 YGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV ::::::::::::::::::::::::::::::: XP_016 YGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNL 220 230 240 250 260 270 XP_016 KHVV >>NP_001159890 (OMIM: 300269) histone deacetylase 8 isof (286 aa) initn: 1586 init1: 1586 opt: 1586 Z-score: 2077.9 bits: 392.8 E(85289): 5.3e-109 Smith-Waterman score: 1748; 75.9% identity (75.9% similar) in 377 aa overlap (1-377:1-286) 10 20 30 40 50 60 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMR----- 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI NP_001 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH :::::::::::::::::::::::::::::::::: NP_001 --------------------------DEASGFCYLNDAVLGILRLRRKFERILYVDLDLH 60 70 80 190 200 210 220 230 240 pF1KB7 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY 90 100 110 120 130 140 250 260 270 280 290 300 pF1KB7 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI 150 160 170 180 190 200 310 320 330 340 350 360 pF1KB7 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH 210 220 230 240 250 260 370 pF1KB7 RIQQILNYIKGNLKHVV ::::::::::::::::: NP_001 RIQQILNYIKGNLKHVV 270 280 >>XP_016885131 (OMIM: 300269) PREDICTED: histone deacety (350 aa) initn: 1564 init1: 1540 opt: 1540 Z-score: 2016.3 bits: 381.7 E(85289): 1.4e-105 Smith-Waterman score: 1702; 75.4% identity (75.4% similar) in 370 aa overlap (1-370:39-317) 10 20 30 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDS :::::::::::::::::::::::::::::: XP_016 GRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH ::::::::::::::::::::::::: XP_016 LAKIPKRASMVHSLIEAYALHKQMR----------------------------------- 70 80 90 100 110 120 130 140 150 pF1KB7 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS :::: XP_016 --------------------------------------------------------DEAS 160 170 180 190 200 210 pF1KB7 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB7 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB7 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE 220 230 240 250 260 270 340 350 360 370 pF1KB7 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV :::::::::::::::::::::::::::::::::::::::: XP_016 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKA 280 290 300 310 320 330 XP_016 KTTEGQRNLKHVV 340 350 >>XP_016885136 (OMIM: 300269) PREDICTED: histone deacety (268 aa) initn: 1264 init1: 1264 opt: 1264 Z-score: 1656.6 bits: 314.7 E(85289): 1.5e-85 Smith-Waterman score: 1438; 89.4% identity (89.4% similar) in 245 aa overlap (1-245:39-257) 10 20 30 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDS :::::::::::::::::::::::::::::: XP_016 GRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG :::::::::::::::::::::::::::::::::: XP_016 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDG-------------------------- 190 200 210 220 220 230 240 250 260 270 pF1KB7 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA ::::::::::::::::::::::::::::::::::: XP_016 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICERYEPPAPNPGL 230 240 250 260 280 290 300 310 320 330 pF1KB7 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE >>XP_016885130 (OMIM: 300269) PREDICTED: histone deacety (389 aa) initn: 1264 init1: 1264 opt: 1264 Z-score: 1654.1 bits: 314.8 E(85289): 2.1e-85 Smith-Waterman score: 2339; 93.1% identity (93.1% similar) in 377 aa overlap (1-377:39-389) 10 20 30 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDS :::::::::::::::::::::::::::::: XP_016 GRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG :::::::::::::::::::::::::::::::::: XP_016 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDG-------------------------- 190 200 210 220 220 230 240 250 260 270 pF1KB7 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB7 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE 290 300 310 320 330 340 340 350 360 370 pF1KB7 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 350 360 370 380 >>XP_016885129 (OMIM: 300269) PREDICTED: histone deacety (415 aa) initn: 1264 init1: 1264 opt: 1264 Z-score: 1653.7 bits: 314.8 E(85289): 2.3e-85 Smith-Waterman score: 2293; 93.0% identity (93.0% similar) in 370 aa overlap (1-370:39-382) 10 20 30 pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDS :::::::::::::::::::::::::::::: XP_016 GRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPG :::::::::::::::::::::::::::::::::: XP_016 GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDG-------------------------- 190 200 210 220 220 230 240 250 260 270 pF1KB7 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIA 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB7 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSE 290 300 310 320 330 340 340 350 360 370 pF1KB7 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV :::::::::::::::::::::::::::::::::::::::: XP_016 IPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKA 350 360 370 380 390 400 XP_016 KTTEGQRNLKHVV 410 377 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:31:01 2016 done: Fri Nov 4 12:31:03 2016 Total Scan time: 6.740 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]