FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7639, 326 aa 1>>>pF1KB7639 326 - 326 aa - 326 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3391+/-0.000814; mu= 8.0124+/- 0.049 mean_var=150.6501+/-29.557, 0's: 0 Z-trim(113.5): 11 B-trim: 0 in 0/52 Lambda= 0.104494 statistics sampled from 14118 (14123) to 14118 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.434), width: 16 Scan time: 3.180 The best scores are: opt bits E(32554) CCDS12597.1 DEDD2 gene_id:162989|Hs108|chr19 ( 326) 2166 337.7 7.9e-93 CCDS59391.1 DEDD2 gene_id:162989|Hs108|chr19 ( 321) 2105 328.5 4.6e-90 CCDS1219.1 DEDD gene_id:9191|Hs108|chr1 ( 318) 828 135.9 4e-32 CCDS81391.1 DEDD gene_id:9191|Hs108|chr1 ( 348) 516 88.9 6.2e-18 >>CCDS12597.1 DEDD2 gene_id:162989|Hs108|chr19 (326 aa) initn: 2166 init1: 2166 opt: 2166 Z-score: 1780.1 bits: 337.7 E(32554): 7.9e-93 Smith-Waterman score: 2166; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD 250 260 270 280 290 300 310 320 pF1KB7 EADYEAGRRRLLLMEEEGGRRPTEAS :::::::::::::::::::::::::: CCDS12 EADYEAGRRRLLLMEEEGGRRPTEAS 310 320 >>CCDS59391.1 DEDD2 gene_id:162989|Hs108|chr19 (321 aa) initn: 1170 init1: 1170 opt: 2105 Z-score: 1730.5 bits: 328.5 E(32554): 4.6e-90 Smith-Waterman score: 2105; 98.5% identity (98.5% similar) in 326 aa overlap (1-326:1-321) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ ::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS59 SSSKRTEGSCRRRRQSSSSANSQQG-----SPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD 240 250 260 270 280 290 310 320 pF1KB7 EADYEAGRRRLLLMEEEGGRRPTEAS :::::::::::::::::::::::::: CCDS59 EADYEAGRRRLLLMEEEGGRRPTEAS 300 310 320 >>CCDS1219.1 DEDD gene_id:9191|Hs108|chr1 (318 aa) initn: 851 init1: 551 opt: 828 Z-score: 690.1 bits: 135.9 E(32554): 4e-32 Smith-Waterman score: 849; 45.8% identity (71.3% similar) in 310 aa overlap (12-312:12-309) 10 20 30 40 50 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLL-DEAPGAAGGL : :.. . .:. ::::::..:: .::. ....:.::. : :: CCDS12 MAGLKRRASQVWPEEHGEQEHGLYSLHRMFDIVGTHLTHRDVRVLSFLFVDVIDDHERGL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 ARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPE---RYS :.: ..:: :::.:.:::::.: . ::::...::::::... :::: : :. .: CCDS12 I--RNGRDFLLALERQGRCDESNFRQVLQLLRIITRHDLLPYVTLKRRRAVCPDLVDKYL 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YGTS---SSSKRTEGSCRRRRQSSSSANSQQGQW--ETGSPPTKRQRRSRGRPSGGARRR :: . . : : :... . :..: .: .::: . :..:. CCDS12 EETSIRYVTPRALSDPEPRPPQPSKTVPPHYPVVCCPTSGPQMCSKRPARGRATLGSQRK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 RRGAPAAPQQQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDV :: . . :. . : :::::::::::::.: ::. .: : . . : ::.. CCDS12 RR----------KSVTPDPKEKQTCDIRLRVRAEYCQHETALQGNVFSNKQDPLERQFER 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 FGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGRE :.::...:.::::::..::::::::.:::::: ::..:.::.::.:::.:..:..:::.: CCDS12 FNQANTILKSRDLGSIICDIKFSELTYLDAFWRDYINGSLLEALKGVFITDSLKQAVGHE 230 240 250 260 270 280 300 310 320 pF1KB7 AVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS :..:::.::: ::: ::..:: CCDS12 AIKLLVNVDEEDYELGRQKLLRNLMLQALP 290 300 310 >>CCDS81391.1 DEDD gene_id:9191|Hs108|chr1 (348 aa) initn: 852 init1: 506 opt: 516 Z-score: 435.4 bits: 88.9 E(32554): 6.2e-18 Smith-Waterman score: 793; 43.0% identity (67.9% similar) in 330 aa overlap (12-312:12-339) 10 20 30 40 50 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLL-DEAPGAAGGL : :.. . .:. ::::::..:: .::. ....:.::. : :: CCDS81 MAGLKRRASQVWPEEHGEQEHGLYSLHRMFDIVGTHLTHRDVRVLSFLFVDVIDDHERGL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 ARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPE---RYS :.: ..:: :::.:.:::::.: . ::::...::::::... :::: : :. .: CCDS81 I--RNGRDFLLALERQGRCDESNFRQVLQLLRIITRHDLLPYVTLKRRRAVCPDLVDKYL 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YGTS---SSSKRTEGSCRRRRQSSSSANSQQGQW--ETGSPPTKRQRRSRGRPSGGARRR :: . . : : :... . :..: .: .::: . :..:. CCDS81 EETSIRYVTPRALSDPEPRPPQPSKTVPPHYPVVCCPTSGPQMCSKRPARGRATLGSQRK 120 130 140 150 160 170 180 190 200 210 pF1KB7 RRGA--PAAPQQQS---------EPARPSSEGKVTCD---------IRLRVRAEYCEHGP :: . : ..:. . .: .: : ::::::::::.: CCDS81 RRKSVTPDPKEKQTCGEEVQGFQRWSRLEGEYKELLGHWAVYAIQYIRLRVRAEYCQHET 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 ALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGAL ::. .: : . . : ::.. :.::...:.::::::..::::::::.:::::: ::..:.: CCDS81 ALQGNVFSNKQDPLERQFERFNQANTILKSRDLGSIICDIKFSELTYLDAFWRDYINGSL 240 250 260 270 280 290 280 290 300 310 320 pF1KB7 LQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS :.::.:::.:..:..:::.::..:::.::: ::: ::..:: CCDS81 LEALKGVFITDSLKQAVGHEAIKLLVNVDEEDYELGRQKLLRNLMLQALP 300 310 320 330 340 326 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:23:10 2016 done: Fri Nov 4 21:23:10 2016 Total Scan time: 3.180 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]