FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7639, 326 aa 1>>>pF1KB7639 326 - 326 aa - 326 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5353+/-0.000339; mu= 6.8598+/- 0.021 mean_var=163.8788+/-33.138, 0's: 0 Z-trim(120.9): 16 B-trim: 798 in 1/54 Lambda= 0.100187 statistics sampled from 36769 (36786) to 36769 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.431), width: 16 Scan time: 9.100 The best scores are: opt bits E(85289) NP_579874 (OMIM: 617078) DNA-binding death effecto ( 326) 2166 324.5 1.8e-88 NP_001257543 (OMIM: 617078) DNA-binding death effe ( 326) 2166 324.5 1.8e-88 NP_001257544 (OMIM: 617078) DNA-binding death effe ( 321) 2105 315.7 8.2e-86 XP_011524874 (OMIM: 617078) PREDICTED: DNA-binding ( 256) 1337 204.6 1.8e-52 XP_011524873 (OMIM: 617078) PREDICTED: DNA-binding ( 299) 1333 204.1 3e-52 XP_016881892 (OMIM: 617078) PREDICTED: DNA-binding ( 327) 1333 204.1 3.3e-52 XP_011524871 (OMIM: 617078) PREDICTED: DNA-binding ( 366) 1333 204.2 3.5e-52 XP_016881891 (OMIM: 617078) PREDICTED: DNA-binding ( 366) 1333 204.2 3.5e-52 NP_001034800 (OMIM: 606841) death effector domain- ( 318) 828 131.1 3e-30 NP_001034801 (OMIM: 606841) death effector domain- ( 318) 828 131.1 3e-30 XP_016858291 (OMIM: 606841) PREDICTED: death effec ( 318) 828 131.1 3e-30 NP_127491 (OMIM: 606841) death effector domain-con ( 318) 828 131.1 3e-30 NP_001317694 (OMIM: 606841) death effector domain- ( 348) 516 86.1 1.2e-16 XP_005245657 (OMIM: 606841) PREDICTED: death effec ( 348) 516 86.1 1.2e-16 XP_005245656 (OMIM: 606841) PREDICTED: death effec ( 348) 516 86.1 1.2e-16 XP_005245655 (OMIM: 606841) PREDICTED: death effec ( 348) 516 86.1 1.2e-16 >>NP_579874 (OMIM: 617078) DNA-binding death effector do (326 aa) initn: 2166 init1: 2166 opt: 2166 Z-score: 1709.1 bits: 324.5 E(85289): 1.8e-88 Smith-Waterman score: 2166; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD 250 260 270 280 290 300 310 320 pF1KB7 EADYEAGRRRLLLMEEEGGRRPTEAS :::::::::::::::::::::::::: NP_579 EADYEAGRRRLLLMEEEGGRRPTEAS 310 320 >>NP_001257543 (OMIM: 617078) DNA-binding death effector (326 aa) initn: 2166 init1: 2166 opt: 2166 Z-score: 1709.1 bits: 324.5 E(85289): 1.8e-88 Smith-Waterman score: 2166; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD 250 260 270 280 290 300 310 320 pF1KB7 EADYEAGRRRLLLMEEEGGRRPTEAS :::::::::::::::::::::::::: NP_001 EADYEAGRRRLLLMEEEGGRRPTEAS 310 320 >>NP_001257544 (OMIM: 617078) DNA-binding death effector (321 aa) initn: 1170 init1: 1170 opt: 2105 Z-score: 1661.6 bits: 315.7 E(85289): 8.2e-86 Smith-Waterman score: 2105; 98.5% identity (98.5% similar) in 326 aa overlap (1-326:1-321) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ ::::::::::::::::::::::::: :::::::::::::::::::::::::::::: NP_001 SSSKRTEGSCRRRRQSSSSANSQQG-----SPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVD 240 250 260 270 280 290 310 320 pF1KB7 EADYEAGRRRLLLMEEEGGRRPTEAS :::::::::::::::::::::::::: NP_001 EADYEAGRRRLLLMEEEGGRRPTEAS 300 310 320 >>XP_011524874 (OMIM: 617078) PREDICTED: DNA-binding dea (256 aa) initn: 1337 init1: 1337 opt: 1337 Z-score: 1063.0 bits: 204.6 E(85289): 1.8e-52 Smith-Waterman score: 1337; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLR ::::::::::::::::: XP_011 QQSEPARPSSEGKVTCDGETGSERHPAPGSSRVLRAWASLGAGRGIPAAPGAGAAAGRVW 190 200 210 220 230 240 >>XP_011524873 (OMIM: 617078) PREDICTED: DNA-binding dea (299 aa) initn: 1329 init1: 1329 opt: 1333 Z-score: 1058.9 bits: 204.1 E(85289): 3e-52 Smith-Waterman score: 1333; 97.6% identity (97.6% similar) in 205 aa overlap (1-204:1-205) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 QQSEPARPSSEGKVTCD-IRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVL :::::::::::::::: : :: : XP_011 QQSEPARPSSEGKVTCGCTRSRVPASASVEDLRKLPFMVEGQGEQACHMTSGSGFEQSTA 190 200 210 220 230 240 >>XP_016881892 (OMIM: 617078) PREDICTED: DNA-binding dea (327 aa) initn: 1329 init1: 1329 opt: 1333 Z-score: 1058.4 bits: 204.1 E(85289): 3.3e-52 Smith-Waterman score: 1333; 97.6% identity (97.6% similar) in 205 aa overlap (1-204:1-205) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 QQSEPARPSSEGKVTCD-IRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVL :::::::::::::::: : :: : XP_016 QQSEPARPSSEGKVTCGCTRSRVPASASVEDLRKLPFMVEGQGEQACHMMGKQAQRGKVT 190 200 210 220 230 240 >>XP_011524871 (OMIM: 617078) PREDICTED: DNA-binding dea (366 aa) initn: 2152 init1: 1329 opt: 1333 Z-score: 1057.7 bits: 204.2 E(85289): 3.5e-52 Smith-Waterman score: 2023; 88.8% identity (88.8% similar) in 358 aa overlap (1-318:1-358) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 pF1KB7 QQSEPARPSSEGKVTC----------------------------------------DIRL :::::::::::::::: :::: XP_011 QQSEPARPSSEGKVTCGCTRSRVPASASVEDLRKLPFMVEGQGEQACHMMGKQAQRDIRL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 RVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLD 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 AFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGR 310 320 330 340 350 360 pF1KB7 RPTEAS XP_011 RPTEAS >>XP_016881891 (OMIM: 617078) PREDICTED: DNA-binding dea (366 aa) initn: 2152 init1: 1329 opt: 1333 Z-score: 1057.7 bits: 204.2 E(85289): 3.5e-52 Smith-Waterman score: 2023; 88.8% identity (88.8% similar) in 358 aa overlap (1-318:1-358) 10 20 30 40 50 60 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQ 130 140 150 160 170 180 190 200 pF1KB7 QQSEPARPSSEGKVTC----------------------------------------DIRL :::::::::::::::: :::: XP_016 QQSEPARPSSEGKVTCGCTRSRVPASASVEDLRKLPFMVEGQGEQACHMMGKQAQRDIRL 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 RVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLD 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 AFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGR 310 320 330 340 350 360 pF1KB7 RPTEAS XP_016 RPTEAS >>NP_001034800 (OMIM: 606841) death effector domain-cont (318 aa) initn: 851 init1: 551 opt: 828 Z-score: 664.1 bits: 131.1 E(85289): 3e-30 Smith-Waterman score: 849; 45.8% identity (71.3% similar) in 310 aa overlap (12-312:12-309) 10 20 30 40 50 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLL-DEAPGAAGGL : :.. . .:. ::::::..:: .::. ....:.::. : :: NP_001 MAGLKRRASQVWPEEHGEQEHGLYSLHRMFDIVGTHLTHRDVRVLSFLFVDVIDDHERGL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 ARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPE---RYS :.: ..:: :::.:.:::::.: . ::::...::::::... :::: : :. .: NP_001 I--RNGRDFLLALERQGRCDESNFRQVLQLLRIITRHDLLPYVTLKRRRAVCPDLVDKYL 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YGTS---SSSKRTEGSCRRRRQSSSSANSQQGQW--ETGSPPTKRQRRSRGRPSGGARRR :: . . : : :... . :..: .: .::: . :..:. NP_001 EETSIRYVTPRALSDPEPRPPQPSKTVPPHYPVVCCPTSGPQMCSKRPARGRATLGSQRK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 RRGAPAAPQQQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDV :: . . :. . : :::::::::::::.: ::. .: : . . : ::.. NP_001 RR----------KSVTPDPKEKQTCDIRLRVRAEYCQHETALQGNVFSNKQDPLERQFER 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 FGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGRE :.::...:.::::::..::::::::.:::::: ::..:.::.::.:::.:..:..:::.: NP_001 FNQANTILKSRDLGSIICDIKFSELTYLDAFWRDYINGSLLEALKGVFITDSLKQAVGHE 230 240 250 260 270 280 300 310 320 pF1KB7 AVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS :..:::.::: ::: ::..:: NP_001 AIKLLVNVDEEDYELGRQKLLRNLMLQALP 290 300 310 >>NP_001034801 (OMIM: 606841) death effector domain-cont (318 aa) initn: 851 init1: 551 opt: 828 Z-score: 664.1 bits: 131.1 E(85289): 3e-30 Smith-Waterman score: 849; 45.8% identity (71.3% similar) in 310 aa overlap (12-312:12-309) 10 20 30 40 50 pF1KB7 MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLL-DEAPGAAGGL : :.. . .:. ::::::..:: .::. ....:.::. : :: NP_001 MAGLKRRASQVWPEEHGEQEHGLYSLHRMFDIVGTHLTHRDVRVLSFLFVDVIDDHERGL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 ARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPE---RYS :.: ..:: :::.:.:::::.: . ::::...::::::... :::: : :. .: NP_001 I--RNGRDFLLALERQGRCDESNFRQVLQLLRIITRHDLLPYVTLKRRRAVCPDLVDKYL 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YGTS---SSSKRTEGSCRRRRQSSSSANSQQGQW--ETGSPPTKRQRRSRGRPSGGARRR :: . . : : :... . :..: .: .::: . :..:. NP_001 EETSIRYVTPRALSDPEPRPPQPSKTVPPHYPVVCCPTSGPQMCSKRPARGRATLGSQRK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 RRGAPAAPQQQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDV :: . . :. . : :::::::::::::.: ::. .: : . . : ::.. NP_001 RR----------KSVTPDPKEKQTCDIRLRVRAEYCQHETALQGNVFSNKQDPLERQFER 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 FGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGRE :.::...:.::::::..::::::::.:::::: ::..:.::.::.:::.:..:..:::.: NP_001 FNQANTILKSRDLGSIICDIKFSELTYLDAFWRDYINGSLLEALKGVFITDSLKQAVGHE 230 240 250 260 270 280 300 310 320 pF1KB7 AVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS :..:::.::: ::: ::..:: NP_001 AIKLLVNVDEEDYELGRQKLLRNLMLQALP 290 300 310 326 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:23:11 2016 done: Fri Nov 4 21:23:12 2016 Total Scan time: 9.100 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]