FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7651, 330 aa 1>>>pF1KB7651 330 - 330 aa - 330 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.9075+/-0.000434; mu= 9.3356+/- 0.027 mean_var=412.3837+/-86.922, 0's: 0 Z-trim(123.0): 162 B-trim: 2473 in 2/56 Lambda= 0.063157 statistics sampled from 41915 (42132) to 41915 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.494), width: 16 Scan time: 9.320 The best scores are: opt bits E(85289) NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 2285 221.8 1.6e-57 NP_001182446 (OMIM: 186770) T-cell leukemia homeob ( 257) 1812 178.5 1.4e-44 XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 1355 137.0 5.4e-32 XP_011538047 (OMIM: 186770) PREDICTED: T-cell leuk ( 269) 1346 136.0 8.4e-32 NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 866 92.4 1.3e-18 NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 852 91.1 3.1e-18 NP_001418 (OMIM: 131310) homeobox protein engraile ( 333) 310 41.8 0.0024 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 307 41.4 0.0027 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 305 41.5 0.0037 NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 296 40.5 0.0056 NP_004089 (OMIM: 269160,600035) homeobox protein E ( 252) 291 39.9 0.007 NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328) 292 40.2 0.0075 NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 ( 354) 290 40.0 0.0089 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 287 39.6 0.0099 NP_001417 (OMIM: 131290) homeobox protein engraile ( 392) 289 40.0 0.01 >>NP_005512 (OMIM: 186770) T-cell leukemia homeobox prot (330 aa) initn: 2285 init1: 2285 opt: 2285 Z-score: 1153.5 bits: 221.8 E(85289): 1.6e-57 Smith-Waterman score: 2285; 100.0% identity (100.0% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KB7 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHN 250 260 270 280 290 300 310 320 330 pF1KB7 SSLFALQNLQPWSDDSTKITSVTSVASACE :::::::::::::::::::::::::::::: NP_005 SSLFALQNLQPWSDDSTKITSVTSVASACE 310 320 330 >>NP_001182446 (OMIM: 186770) T-cell leukemia homeobox p (257 aa) initn: 1812 init1: 1812 opt: 1812 Z-score: 921.6 bits: 178.5 E(85289): 1.4e-44 Smith-Waterman score: 1812; 100.0% identity (100.0% similar) in 257 aa overlap (1-257:1-257) 10 20 30 40 50 60 pF1KB7 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHN ::::::::::::::::: NP_001 TDAQVKTWFQNRRTKWR 250 >>XP_011538046 (OMIM: 186770) PREDICTED: T-cell leukemia (342 aa) initn: 1346 init1: 1346 opt: 1355 Z-score: 695.4 bits: 137.0 E(85289): 5.4e-32 Smith-Waterman score: 2251; 96.5% identity (96.5% similar) in 342 aa overlap (1-330:1-342) 10 20 30 40 50 60 pF1KB7 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN 130 140 150 160 170 180 190 200 210 220 pF1KB7 RRYTKDRFT------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLAS ::::::::: ::::::::::::::::::::::::::::::::::::::: XP_011 RRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLAS 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 AERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLA 250 260 270 280 290 300 290 300 310 320 330 pF1KB7 QPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE :::::::::::::::::::::::::::::::::::::::::: XP_011 QPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE 310 320 330 340 >>XP_011538047 (OMIM: 186770) PREDICTED: T-cell leukemia (269 aa) initn: 1346 init1: 1346 opt: 1346 Z-score: 691.9 bits: 136.0 E(85289): 8.4e-32 Smith-Waterman score: 1778; 95.5% identity (95.5% similar) in 269 aa overlap (1-257:1-269) 10 20 30 40 50 60 pF1KB7 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN 130 140 150 160 170 180 190 200 210 220 pF1KB7 RRYTKDRFT------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLAS ::::::::: ::::::::::::::::::::::::::::::::::::::: XP_011 RRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLAS 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 AERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLA ::::::::::::::::::::::::::::: XP_011 AERAALAKALKMTDAQVKTWFQNRRTKWR 250 260 >>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa) initn: 1021 init1: 715 opt: 866 Z-score: 455.4 bits: 92.4 E(85289): 1.3e-18 Smith-Waterman score: 1043; 55.5% identity (68.8% similar) in 337 aa overlap (4-327:6-282) 10 20 30 40 50 pF1KB7 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYG ::::.: : : :::::::::::..:. : : ::: : NP_057 MEPGMLGPHNL-PHH-EPISFGIDQILSGPETPG----------GGLGLG--------RG 10 20 30 40 60 70 80 90 100 110 pF1KB7 GGGSAAATGAGGAGAYGTGGPGGPG-GPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGG : : : ::.. : :. : :::: :..:: :: .: :::: NP_057 GQGH------GENGAFSGGYHGASGYGPAG-----SLAPLPGS--------SGVGPGG-- 50 60 70 120 130 140 150 160 170 pF1KB7 GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWM :::::::::: : : : : :.::. .. :...:.::::::: NP_057 -------------VIRVPAHRPLP----VPPP-AGGAPAVPGPSGLGGAGGLAGLTFPWM 80 90 100 110 120 180 190 200 210 220 pF1KB7 ESNRRYTKDRFT------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKY .:.::..:::.: :::::::::::.:::::::.: :. :::.:: :::: NP_057 DSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKY 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB7 LASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQK :::::::::::::.:::::::::::::::::::::::::::::..:.:.::.:::.:. . NP_057 LASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPR 190 200 210 220 230 240 290 300 310 320 330 pF1KB7 SLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE : ::: ::::.::::::::::::::..:. :..::...:: NP_057 PLRPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLASVV 250 260 270 280 >>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa) initn: 1111 init1: 792 opt: 852 Z-score: 448.4 bits: 91.1 E(85289): 3.1e-18 Smith-Waterman score: 1127; 59.6% identity (71.7% similar) in 332 aa overlap (10-325:11-290) 10 20 30 40 50 pF1KB7 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGG :: : :::::::::::::::: . .:: : :: :: NP_066 MEAPASAQTPHP-H-EPISFGIDQILNSPDQDS--APAPRGPDGASYLG----------- 10 20 30 40 60 70 80 90 100 110 pF1KB7 GGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPL--TGSYNVNMALAGGPGPGGGG : : : :. :. :.. :: :. :. .:::.::..:: : NP_066 -------GPPG-GRPGATYPSLPASFAGLGA-----PFEDAGSYSVNLSLA--P------ 50 60 70 80 120 130 140 150 160 170 pF1KB7 GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWM :::::::::::: ::: : :: ..::..::::. :..: ::.:::: NP_066 -----------AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWM 90 100 110 120 180 190 200 210 220 pF1KB7 ESNRRYTKDRFT--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQ ::.::..::::: :::::::::::.:::::::.:.:::::::::::: NP_066 ESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQ 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB7 KYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAF :::::::::::::.::::::::::::::::::::::::::::::::::.:..::::..:: NP_066 KYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAF 190 200 210 220 230 240 290 300 310 320 330 pF1KB7 QKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE :::: . . ::::.:::::::::::::: .::.:. .:::. NP_066 QKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV 250 260 270 280 290 >>NP_001418 (OMIM: 131310) homeobox protein engrailed-2 (333 aa) initn: 348 init1: 170 opt: 310 Z-score: 180.9 bits: 41.8 E(85289): 0.0024 Smith-Waterman score: 320; 34.5% identity (60.2% similar) in 226 aa overlap (61-263:86-306) 40 50 60 70 80 90 pF1KB7 GGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGG :. : ::::. . :.:: :: .: :::: NP_001 APGNHQHPHRITNFFIDNILRPEFGRRKDAGTCCA-GAGGGRGGGAGGEGGASGAEGGGG 60 70 80 90 100 110 100 110 120 130 pF1KB7 ACSMGPLTGS------YNVNMAL-AGGPGPGGG----GGSSGGAGALSAAGVIRVPAHR- : . : :: : : :::: :..: : . ::. .:: : . . NP_001 AGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPG 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB7 -PLAGAVAHPQPLATGLPTVPSVP--AMPGVN-NLTGLTFP-WMESNRRYTKDRFTGHPY :: :.. . . :. : .: : .. :.: . . .: :. .: :. :: .. : NP_001 GPLDGSL-KARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTR-YS-DRPSSGP- 180 190 200 210 220 230 200 210 220 230 240 pF1KB7 QNRTPPKK------KKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKT ..: : :: :.:::.:: :. .:. .:. ..::. .: .::. :.....:.: NP_001 RSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKI 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB7 WFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQ ::::.:.: .. :... NP_001 WFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE 300 310 320 330 >>NP_000200 (OMIM: 125853,260370,600733,606176,606392) p (283 aa) initn: 236 init1: 236 opt: 307 Z-score: 180.1 bits: 41.4 E(85289): 0.0027 Smith-Waterman score: 307; 32.0% identity (56.9% similar) in 197 aa overlap (111-295:49-244) 90 100 110 120 130 140 pF1KB7 GPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPAHRPL : ::. :. :. . . : : NP_000 AFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPA 20 30 40 50 60 70 150 160 170 180 190 pF1KB7 AGAVAHPQPLATGLPTVPSVP----AMPGV---NNLTGLTFPWMESNRRYT-KDRFTGHP .. . : : .:: :. : : ::: : . : ::::.:.. .. : ...: NP_000 VAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGA 80 90 100 110 120 130 200 210 220 230 240 250 pF1KB7 YQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNR : . : ..:. ::..:: :. ::::.: .::.. .:. :: :..:. ..: ::::: NP_000 YAAE-PEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNR 140 150 160 170 180 190 260 270 280 290 300 pF1KB7 RTKWRRQTAEEREAERQQANRILLQLQQEAFQKS----LAQPLPADPLCVHNSSLFALQN : ::... ..: . .. . . .:. : :: : : : NP_000 RMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAR 200 210 220 230 240 250 310 320 330 pF1KB7 LQPWSDDSTKITSVTSVASACE NP_000 EGRLPPGLSASPQPSSVAPRRPQEPR 260 270 280 >>NP_005506 (OMIM: 142994,176450) motor neuron and pancr (401 aa) initn: 312 init1: 240 opt: 305 Z-score: 177.8 bits: 41.5 E(85289): 0.0037 Smith-Waterman score: 323; 35.4% identity (58.7% similar) in 223 aa overlap (67-270:98-314) 40 50 60 70 80 90 pF1KB7 ASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGP ::::.:. :: ::: : :.: . . NP_005 APADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAA 70 80 90 100 110 120 100 110 120 130 140 pF1KB7 LTGSYNVNMALAGGPGPG-GGGGSSGGAGALSAAGVIRVPAHRPLAGAVA------HPQP ... : ::: . : ::..:::: . :.. :.. :.:.: :: NP_005 AAAA-----AAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPA- 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB7 LATGLPTVPSV-PAMPGVNNLTGL-TFP---WME-SNRRYTKDRFTGHPYQNRTP--PKK :. . : : .. :: :. : :: :.. :. . .. : .. : NP_005 LSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKC 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 KKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRR-QT ..:::.:: :. :::..:. .:::. .: .: .: .:..::: :::::: ::.: . NP_005 RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKK 250 260 270 280 290 300 270 280 290 300 310 pF1KB7 AEER---EAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDST :.:. :::.:. NP_005 AKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDSDPEEDED 310 320 330 340 350 360 >>NP_002439 (OMIM: 106600,142983,189500,608874) homeobox (303 aa) initn: 266 init1: 205 opt: 296 Z-score: 174.4 bits: 40.5 E(85289): 0.0056 Smith-Waterman score: 296; 28.1% identity (53.1% similar) in 288 aa overlap (34-304:1-272) 10 20 30 40 50 60 pF1KB7 LGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSA :.::. . . :. .. .:::.. NP_002 MAPAADMTSLPLGVKVEDSAFGKPAGGGAG 10 20 30 70 80 90 100 110 120 pF1KB7 AATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGA : .:..: : . :. . : ...: ..:. .: ::. .. . . NP_002 QAPSAAAATAAAMGADEEGAKP-------KVSPSLLPFSVEALMADHRKPGAKESALAPS 40 50 60 70 80 130 140 150 160 170 pF1KB7 GALSAAGVIRVPAHRPLAG-----AVAHPQPLAT----GLPTVPSVPAMPGVNNLTGLTF ...::: : : .. : . :.::. :: .: . . . NP_002 EGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERT 90 100 110 120 130 140 180 190 200 210 220 pF1KB7 PWMESNRRYTKDRFTGHPYQNRTPP-----KKK---KPRTSFTRLQICELEKRFHRQKYL :::.: ::. : . .:: :.: :::: :: :. ::..:....:: NP_002 PWMQS------PRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYL 150 160 170 180 190 230 240 250 260 270 280 pF1KB7 ASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKS . :::: ....:..:..::: ::::::.: .: : : .. :. .: :: : NP_002 SIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPML---PPAAFGLS 200 210 220 230 240 250 290 300 310 320 330 pF1KB7 LAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE . :: . ..::. NP_002 FPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT 260 270 280 290 300 330 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:25:16 2016 done: Fri Nov 4 21:25:17 2016 Total Scan time: 9.320 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]