FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7661, 335 aa 1>>>pF1KB7661 335 - 335 aa - 335 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0352+/-0.000686; mu= 14.3509+/- 0.042 mean_var=98.9792+/-20.328, 0's: 0 Z-trim(113.0): 72 B-trim: 335 in 1/52 Lambda= 0.128915 statistics sampled from 13650 (13722) to 13650 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.422), width: 16 Scan time: 3.070 The best scores are: opt bits E(32554) CCDS4794.1 SPDEF gene_id:25803|Hs108|chr6 ( 335) 2307 438.7 3.1e-123 CCDS59013.1 SPDEF gene_id:25803|Hs108|chr6 ( 319) 1461 281.4 6.9e-76 CCDS56424.1 ETV7 gene_id:51513|Hs108|chr6 ( 264) 392 82.5 4.2e-16 CCDS7893.1 ELF5 gene_id:2001|Hs108|chr11 ( 255) 331 71.1 1.1e-12 CCDS7892.1 ELF5 gene_id:2001|Hs108|chr11 ( 265) 331 71.1 1.1e-12 CCDS45043.1 ELF1 gene_id:1997|Hs108|chr13 ( 595) 307 66.9 4.6e-11 CCDS9374.1 ELF1 gene_id:1997|Hs108|chr13 ( 619) 307 67.0 4.7e-11 CCDS59165.1 ELK1 gene_id:2002|Hs108|chrX ( 95) 295 64.1 5.2e-11 CCDS64063.1 ELF2 gene_id:1998|Hs108|chr4 ( 504) 305 66.5 5.2e-11 CCDS64062.1 ELF2 gene_id:1998|Hs108|chr4 ( 521) 305 66.5 5.3e-11 CCDS3745.1 ELF2 gene_id:1998|Hs108|chr4 ( 533) 305 66.5 5.4e-11 CCDS3744.1 ELF2 gene_id:1998|Hs108|chr4 ( 581) 305 66.6 5.8e-11 CCDS82954.1 ELF2 gene_id:1998|Hs108|chr4 ( 593) 305 66.6 5.9e-11 CCDS14617.1 ELF4 gene_id:2000|Hs108|chrX ( 663) 303 66.2 8.3e-11 >>CCDS4794.1 SPDEF gene_id:25803|Hs108|chr6 (335 aa) initn: 2307 init1: 2307 opt: 2307 Z-score: 2325.9 bits: 438.7 E(32554): 3.1e-123 Smith-Waterman score: 2307; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB7 MGSASPGLSSVSPSHLLLPPDTVSRTGLEKAAAGAVGLERRDWSPSPPATPEQGLSAFYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MGSASPGLSSVSPSHLLLPPDTVSRTGLEKAAAGAVGLERRDWSPSPPATPEQGLSAFYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SYFDMLYPEDSSWAAKAPGASSREEPPEEPEQCPVIDSQAPAGSLDLVPGGLTLEEHSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SYFDMLYPEDSSWAAKAPGASSREEPPEEPEQCPVIDSQAPAGSLDLVPGGLTLEEHSLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 KELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHYCASTSEESWTDSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHYCASTSEESWTDSEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAM 250 260 270 280 290 300 310 320 330 pF1KB7 NYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI ::::::::::::::::::::::::::::::::::: CCDS47 NYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI 310 320 330 >>CCDS59013.1 SPDEF gene_id:25803|Hs108|chr6 (319 aa) initn: 1456 init1: 1456 opt: 1461 Z-score: 1475.9 bits: 281.4 E(32554): 6.9e-76 Smith-Waterman score: 2145; 95.2% identity (95.2% similar) in 335 aa overlap (1-335:1-319) 10 20 30 40 50 60 pF1KB7 MGSASPGLSSVSPSHLLLPPDTVSRTGLEKAAAGAVGLERRDWSPSPPATPEQGLSAFYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MGSASPGLSSVSPSHLLLPPDTVSRTGLEKAAAGAVGLERRDWSPSPPATPEQGLSAFYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SYFDMLYPEDSSWAAKAPGASSREEPPEEPEQCPVIDSQAPAGSLDLVPGGLTLEEHSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SYFDMLYPEDSSWAAKAPGASSREEPPEEPEQCPVIDSQAPAGSLDLVPGGLTLEEHSLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 KELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHYCASTSEESWTDSEV :::::::::::::::::::::::::::::::: :::::::::::: CCDS59 KELCAMSEEQFRQRSPLGGDVLHAHLDIWKSA----------------STSEESWTDSEV 190 200 210 220 250 260 270 280 290 300 pF1KB7 DSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAM 230 240 250 260 270 280 310 320 330 pF1KB7 NYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI ::::::::::::::::::::::::::::::::::: CCDS59 NYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI 290 300 310 >>CCDS56424.1 ETV7 gene_id:51513|Hs108|chr6 (264 aa) initn: 387 init1: 198 opt: 392 Z-score: 402.5 bits: 82.5 E(32554): 4.2e-16 Smith-Waterman score: 392; 34.8% identity (65.7% similar) in 201 aa overlap (138-332:41-228) 110 120 130 140 150 160 pF1KB7 VPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLN-ITADPMDWSPSNVQKWLLWTEHQY ::: . . .: :: .: .:: :.:..: CCDS56 ISPVAAMPPLGTHVQARCEAQINLLGEGGICKLPGRLRIQPALWSREDVLHWLRWAEQEY 20 30 40 50 60 70 170 180 190 200 210 220 pF1KB7 RLPPMGKAFQELAGKELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKERT---SP-- :: .. :. :. :: .....::.:.: .::::. :. :. ..:. .: CCDS56 SLPCTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYIKT----QRRALVCGPFF 80 90 100 110 120 230 240 250 260 270 280 pF1KB7 GAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKI :.: . ...: . : .: ::... .::: . : .:.: .:. ::.. CCDS56 GGIFRLKTPTQHSPVPPE---DCR----LLWDYVYQLLLDTR-YEPYIKWEDKDAKIFRV 130 140 150 160 170 290 300 310 320 330 pF1KB7 EDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI : .::::: .::: :.:.:.::..:.::: .::.: . .:.:...:. CCDS56 VDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKK-EPGQKLLFRFLKTPGKMVQD 180 190 200 210 220 230 CCDS56 KHSHLEPLESQEQDRIEFKDKRPEISP 240 250 260 >>CCDS7893.1 ELF5 gene_id:2001|Hs108|chr11 (255 aa) initn: 324 init1: 261 opt: 331 Z-score: 341.4 bits: 71.1 E(32554): 1.1e-12 Smith-Waterman score: 392; 33.3% identity (60.9% similar) in 207 aa overlap (135-331:39-243) 110 120 130 140 150 160 pF1KB7 LDLVPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEH .::: .. : :. .: .:: . CCDS78 TFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCD 10 20 30 40 50 60 170 180 190 200 210 pF1KB7 QYRLPPMGKAFQE--LAGKELCAMSEEQFRQRSPLGGDVLHAHLD--------IWKSAAW ::.: .: . ..: .::.:..:.: . . : :. :. :. ....: CCDS78 QYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQGYSFFNDAEE 70 80 90 100 110 120 220 230 240 250 260 270 pF1KB7 MKERTSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNK : . : : .:: . : . : : : :::.:...:::.:. ...: .. CCDS78 SKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDR 130 140 150 160 170 180 280 290 300 310 320 330 pF1KB7 EKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHP :.:::.. : .:..:: ::. :.:.::::..: ::: ::... : .::::.: CCDS78 EQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD--RRLVYKFGKN 190 200 210 220 230 240 pF1KB7 I CCDS78 AHGWQEDKL 250 >>CCDS7892.1 ELF5 gene_id:2001|Hs108|chr11 (265 aa) initn: 324 init1: 261 opt: 331 Z-score: 341.2 bits: 71.1 E(32554): 1.1e-12 Smith-Waterman score: 392; 33.3% identity (60.9% similar) in 207 aa overlap (135-331:49-253) 110 120 130 140 150 160 pF1KB7 LDLVPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEH .::: .. : :. .: .:: . CCDS78 TFLPNASFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCD 20 30 40 50 60 70 170 180 190 200 210 pF1KB7 QYRLPPMGKAFQE--LAGKELCAMSEEQFRQRSPLGGDVLHAHLD--------IWKSAAW ::.: .: . ..: .::.:..:.: . . : :. :. :. ....: CCDS78 QYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCGEYLYFILQNIRTQGYSFFNDAEE 80 90 100 110 120 130 220 230 240 250 260 270 pF1KB7 MKERTSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNK : . : : .:: . : . : : : :::.:...:::.:. ...: .. CCDS78 SKATIKDYADSNCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDR 140 150 160 170 180 190 280 290 300 310 320 330 pF1KB7 EKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHP :.:::.. : .:..:: ::. :.:.::::..: ::: ::... : .::::.: CCDS78 EQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVD--RRLVYKFGKN 200 210 220 230 240 250 pF1KB7 I CCDS78 AHGWQEDKL 260 >>CCDS45043.1 ELF1 gene_id:1997|Hs108|chr13 (595 aa) initn: 291 init1: 257 opt: 307 Z-score: 312.1 bits: 66.9 E(32554): 4.6e-11 Smith-Waterman score: 307; 43.0% identity (70.2% similar) in 114 aa overlap (218-331:155-265) 190 200 210 220 230 240 pF1KB7 EEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHYCASTSEESWTDSEVDSSCSGQ .:.: :.: . : .. :.. :. CCDS45 EVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGK--GN 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB7 PIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSR :.::.:: :: . ..:.: ..::::::. :: :.:::: .::.: :::. ..: CCDS45 TIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGR 190 200 210 220 230 240 310 320 330 pF1KB7 SIRQYYKKGIIRKPDISQRLVYQFVHPI ..: ::..::. : . .::::::: CCDS45 ALRYYYQRGILAKVE-GQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQ 250 260 270 280 290 300 >>CCDS9374.1 ELF1 gene_id:1997|Hs108|chr13 (619 aa) initn: 291 init1: 257 opt: 307 Z-score: 311.9 bits: 67.0 E(32554): 4.7e-11 Smith-Waterman score: 307; 43.0% identity (70.2% similar) in 114 aa overlap (218-331:179-289) 190 200 210 220 230 240 pF1KB7 EEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHYCASTSEESWTDSEVDSSCSGQ .:.: :.: . : .. :.. :. CCDS93 EVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGK--GN 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB7 PIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSR :.::.:: :: . ..:.: ..::::::. :: :.:::: .::.: :::. ..: CCDS93 TIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGR 210 220 230 240 250 260 310 320 330 pF1KB7 SIRQYYKKGIIRKPDISQRLVYQFVHPI ..: ::..::. : . .::::::: CCDS93 ALRYYYQRGILAKVE-GQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQ 270 280 290 300 310 320 >>CCDS59165.1 ELK1 gene_id:2002|Hs108|chrX (95 aa) initn: 242 init1: 242 opt: 295 Z-score: 311.2 bits: 64.1 E(32554): 5.2e-11 Smith-Waterman score: 295; 52.4% identity (79.8% similar) in 84 aa overlap (249-332:5-86) 220 230 240 250 260 270 pF1KB7 TSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGI . ::::: .:: . .. :..: : ... : CCDS59 MDPSVTLWQFLLQLL-REQGNGHIISWTSRDGGE 10 20 30 280 290 300 310 320 330 pF1KB7 FKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI ::. :. .::::::.:::. ::::::::..: :: :.:::: . .:..::.:: CCDS59 FKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVS-GQKFVYKFVSYPESH 40 50 60 70 80 90 CCDS59 CAP >>CCDS64063.1 ELF2 gene_id:1998|Hs108|chr4 (504 aa) initn: 317 init1: 263 opt: 305 Z-score: 311.1 bits: 66.5 E(32554): 5.2e-11 Smith-Waterman score: 305; 48.8% identity (77.9% similar) in 86 aa overlap (246-331:116-200) 220 230 240 250 260 270 pF1KB7 KERTSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKE :. .::.:: .:: .. :.:.: ..: CCDS64 VEVSTEESEPMDTSPIPTSPDSHEPMKKKKGNTTYLWEFLLDLLQDKNTCPRYIKWTQRE 90 100 110 120 130 140 280 290 300 310 320 330 pF1KB7 KGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI :::::. :: :..::: .::.: :::. ..:..: ::..::. : . .::::::: CCDS64 KGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVE-GQRLVYQFKDMP 150 160 170 180 190 200 CCDS64 KNIVVIDDDKSETCNEDLAGTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINCSRAEK 210 220 230 240 250 260 >>CCDS64062.1 ELF2 gene_id:1998|Hs108|chr4 (521 aa) initn: 293 init1: 263 opt: 305 Z-score: 310.9 bits: 66.5 E(32554): 5.3e-11 Smith-Waterman score: 305; 48.8% identity (77.9% similar) in 86 aa overlap (246-331:133-217) 220 230 240 250 260 270 pF1KB7 KERTSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKE :. .::.:: .:: .. :.:.: ..: CCDS64 KVGRKPKTQQSPISNGSPELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQRE 110 120 130 140 150 160 280 290 300 310 320 330 pF1KB7 KGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI :::::. :: :..::: .::.: :::. ..:..: ::..::. : . .::::::: CCDS64 KGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVE-GQRLVYQFKDMP 170 180 190 200 210 220 CCDS64 KNIVVIDDDKSETCNEDLAGTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINCSRAEK 230 240 250 260 270 280 335 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:54:25 2016 done: Sat Nov 5 09:54:26 2016 Total Scan time: 3.070 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]