Result of FASTA (ccds) for pF1KB7666
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7666, 371 aa
  1>>>pF1KB7666 371 - 371 aa - 371 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3281+/-0.000862; mu= 5.6172+/- 0.052
 mean_var=238.1151+/-49.166, 0's: 0 Z-trim(114.9): 54  B-trim: 385 in 1/53
 Lambda= 0.083115
 statistics sampled from 15370 (15423) to 15370 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.474), width:  16
 Scan time:  3.030

The best scores are:                                      opt bits E(32554)
CCDS47123.1 LEF1 gene_id:51176|Hs108|chr4          ( 371) 2609 325.2 5.5e-89
CCDS47122.1 LEF1 gene_id:51176|Hs108|chr4          ( 386) 2546 317.7 1.1e-86
CCDS54791.1 LEF1 gene_id:51176|Hs108|chr4          ( 303) 2128 267.5 1.1e-71
CCDS3679.1 LEF1 gene_id:51176|Hs108|chr4           ( 399) 1524 195.2 8.5e-50
CCDS4169.1 TCF7 gene_id:6932|Hs108|chr5            ( 384) 1042 137.4 2.1e-32
CCDS4170.1 TCF7 gene_id:6932|Hs108|chr5            ( 269)  851 114.3 1.3e-25
CCDS43362.1 TCF7 gene_id:6932|Hs108|chr5           ( 268)  848 113.9 1.6e-25
CCDS47263.2 TCF7 gene_id:6932|Hs108|chr5           ( 269)  848 113.9 1.6e-25
CCDS73198.1 TCF7L2 gene_id:6934|Hs108|chr10        ( 408)  798 108.1 1.4e-23
CCDS53577.1 TCF7L2 gene_id:6934|Hs108|chr10        ( 602)  801 108.7 1.4e-23
CCDS73197.1 TCF7L2 gene_id:6934|Hs108|chr10        ( 579)  796 108.0 2.1e-23
CCDS55729.1 TCF7L2 gene_id:6934|Hs108|chr10        ( 459)  793 107.6 2.3e-23
CCDS7576.1 TCF7L2 gene_id:6934|Hs108|chr10         ( 596)  793 107.7 2.7e-23
CCDS53578.1 TCF7L2 gene_id:6934|Hs108|chr10        ( 489)  791 107.4 2.8e-23
CCDS81504.1 TCF7L2 gene_id:6934|Hs108|chr10        ( 455)  788 107.0 3.4e-23
CCDS73196.1 TCF7L2 gene_id:6934|Hs108|chr10        ( 476)  787 106.9 3.9e-23
CCDS1971.1 TCF7L1 gene_id:83439|Hs108|chr2         ( 588)  734 100.6 3.7e-21


>>CCDS47123.1 LEF1 gene_id:51176|Hs108|chr4               (371 aa)
 initn: 2609 init1: 2609 opt: 2609  Z-score: 1711.0  bits: 325.2 E(32554): 5.5e-89
Smith-Waterman score: 2609; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371)

               10        20        30        40        50        60
pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS
              310       320       330       340       350       360

              370 
pF1KB7 GTGPRMTAAYI
       :::::::::::
CCDS47 GTGPRMTAAYI
              370 

>>CCDS47122.1 LEF1 gene_id:51176|Hs108|chr4               (386 aa)
 initn: 2544 init1: 2544 opt: 2546  Z-score: 1670.0  bits: 317.7 E(32554): 1.1e-86
Smith-Waterman score: 2546; 99.5% identity (99.5% similar) in 365 aa overlap (1-365:1-364)

               10        20        30        40        50        60
pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS
              310       320       330       340       350       360

              370                 
pF1KB7 GTGPRMTAAYI                
       : : :                      
CCDS47 G-GKRSSFPTCKAKAATPGPLLEMEAC
               370       380      

>>CCDS54791.1 LEF1 gene_id:51176|Hs108|chr4               (303 aa)
 initn: 2128 init1: 2128 opt: 2128  Z-score: 1400.4  bits: 267.5 E(32554): 1.1e-71
Smith-Waterman score: 2128; 100.0% identity (100.0% similar) in 301 aa overlap (71-371:3-303)

               50        60        70        80        90       100
pF1KB7 ISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGG
                                     ::::::::::::::::::::::::::::::
CCDS54                             MAEVARQAQTSQEPYHDKAREHPDDGKHPDGG
                                           10        20        30  

              110       120       130       140       150       160
pF1KB7 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY
             40        50        60        70        80        90  

              170       180       190       200       210       220
pF1KB7 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIP
            100       110       120       130       140       150  

              230       240       250       260       270       280
pF1KB7 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML
            160       170       180       190       200       210  

              290       300       310       320       330       340
pF1KB7 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA
            220       230       240       250       260       270  

              350       360       370 
pF1KB7 RDNYGKKKKRKREKLQESASGTGPRMTAAYI
       :::::::::::::::::::::::::::::::
CCDS54 RDNYGKKKKRKREKLQESASGTGPRMTAAYI
            280       290       300   

>>CCDS3679.1 LEF1 gene_id:51176|Hs108|chr4                (399 aa)
 initn: 1514 init1: 1514 opt: 1524  Z-score: 1007.5  bits: 195.2 E(32554): 8.5e-50
Smith-Waterman score: 2543; 93.0% identity (93.0% similar) in 399 aa overlap (1-371:1-399)

               10        20        30        40        50        60
pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
              130       140       150       160       170       180

              190       200       210                              
pF1KB7 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW---------------------------
       :::::::::::::::::::::::::::::::::                           
CCDS36 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
              190       200       210       220       230       240

            220       230       240       250       260       270  
pF1KB7 -FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
              250       260       270       280       290       300

            280       290       300       310       320       330  
pF1KB7 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
              310       320       330       340       350       360

            340       350       360       370 
pF1KB7 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI
       :::::::::::::::::::::::::::::::::::::::
CCDS36 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI
              370       380       390         

>>CCDS4169.1 TCF7 gene_id:6932|Hs108|chr5                 (384 aa)
 initn: 867 init1: 568 opt: 1042  Z-score: 695.3  bits: 137.4 E(32554): 2.1e-32
Smith-Waterman score: 1062; 50.3% identity (68.1% similar) in 386 aa overlap (1-365:1-362)

               10        20        30        40        50        60
pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
       ::::..::::.::  .: : ::.. :.:::. : .:     . ::.  :::..:::::::
CCDS41 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE
               10        20        30        40          50        

                     70                80        90          100   
pF1KB7 SEI------IPASNGH--------EVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN
       ::       ::.  :         :.  . ...:. . ::  :  .:: : :.  .:.:.
CCDS41 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK
       60        70        80        90       100       110        

           110       120       130       140       150       160   
pF1KB7 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE
       .    . ::.. ..  :.  :  . :.   : :   .   . :: :.:  :.    :  :
CCDS41 E----TVYSAFNLL--MHYPPPSGAGQHPQPQPPLHK---ANQPPHGVPQLS---LY--E
          120         130       140          150       160         

            170       180       190       200       210            
pF1KB7 HF-SPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMI---
       :: ::  ::.  :.:...:: . :   .::.  :: :. :..::.   ..::.:  .   
CCDS41 HFNSP--HPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLG
            170       180        190       200       210       220 

     220       230       240       250       260       270         
pF1KB7 PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFM
        : :: : ..::::::: :. :::    : .:   : : :.. :.: :.: :::::::::
CCDS41 SGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFM
              230       240       250          260       270       

     280       290       300       310       320       330         
pF1KB7 LYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWS
       ::::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWS
       280       290       300       310       320       330       

     340       350       360       370                 
pF1KB7 ARDNYGKKKKRKREKLQESASGTGPRMTAAYI                
       :::::::::.:.::: :::..: : :                      
CCDS41 ARDNYGKKKRRSREKHQESTTG-GKRNAFGTYPEKAAAPAPFLPMTVL
       340       350        360       370       380    

>>CCDS4170.1 TCF7 gene_id:6932|Hs108|chr5                 (269 aa)
 initn: 719 init1: 568 opt: 851  Z-score: 573.5  bits: 114.3 E(32554): 1.3e-25
Smith-Waterman score: 859; 56.4% identity (72.2% similar) in 259 aa overlap (111-365:7-247)

               90       100       110       120       130       140
pF1KB7 EPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSN
                                     ::.. ..  :.  :  . :.   : :   .
CCDS41                         MYKETVYSAFNLL--MHYPPPSGAGQHPQPQPPLHK
                                       10          20        30    

              150       160        170       180       190         
pF1KB7 KVPVVQPSHAVHPLTPLITYSDEHF-SPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPL
          . :: :.:  :.    :  ::: ::  ::.  :.:...:: . :   .::.  :: :
CCDS41 ---ANQPPHGVPQLS---LY--EHFNSP--HPTPAPADISQKQ-VHRPLQTPDLSGFYSL
              40             50          60         70        80   

     200       210          220       230       240       250      
pF1KB7 SPGGVGQITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKP
       . :..::.   ..::.:  .    : :: : ..::::::: :. :::    : .:   : 
CCDS41 TSGSMGQLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KT
            90       100       110        120       130            

        260       270       280       290       300       310      
pF1KB7 QHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREE
       : :.. :.: :.: :::::::::::::::::.:.::::::::::::::::::::::::::
CCDS41 QAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREE
     140       150       160       170       180       190         

        320       330       340       350       360       370      
pF1KB7 QAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI     
       ::::::::::::::::::::::::::::::::.:.::: :::..: : :           
CCDS41 QAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTG-GKRNAFGTYPEKAA
     200       210       220       230       240        250        

CCDS41 APAPFLPMTVL
      260         

>>CCDS43362.1 TCF7 gene_id:6932|Hs108|chr5                (268 aa)
 initn: 717 init1: 566 opt: 848  Z-score: 571.6  bits: 113.9 E(32554): 1.6e-25
Smith-Waterman score: 856; 55.8% identity (71.9% similar) in 260 aa overlap (111-365:7-249)

               90       100       110       120       130       140
pF1KB7 EPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSN
                                     ::.. ..  :.  :  . :.   : :   .
CCDS43                         MYKETVYSAFNLL--MHYPPPSGAGQHPQPQPPLHK
                                       10          20        30    

              150       160        170       180       190         
pF1KB7 KVPVVQPSHAVHPLTPLITYSDEHF-SPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPL
          . :: :.:  :.    :  ::: ::  ::.  :.:...:: . :   .::.  :: :
CCDS43 ---ANQPPHGVPQLS---LY--EHFNSP--HPTPAPADISQKQ-VHRPLQTPDLSGFYSL
              40             50          60         70        80   

     200       210          220       230       240       250      
pF1KB7 SPGGVGQITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKP
       . :..::.   ..::.:  .    : :: : ..::::::: :. :::    : .:   : 
CCDS43 TSGSMGQLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KT
            90       100       110        120       130            

        260       270       280       290       300       310      
pF1KB7 QHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREE
       : :.. :.: :.: :::::::::::::::::.:.::::::::::::::::::::::::::
CCDS43 QAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREE
     140       150       160       170       180       190         

        320       330       340       350       360        370     
pF1KB7 QAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTG-PRMTAAYI    
       ::::::::::::::::::::::::::::::::.:.::: :::..  : :.          
CCDS43 QAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARFGLNQ
     200       210       220       230       240       250         

CCDS43 QTDWCGPCR
     260        

>>CCDS47263.2 TCF7 gene_id:6932|Hs108|chr5                (269 aa)
 initn: 713 init1: 562 opt: 848  Z-score: 571.5  bits: 113.9 E(32554): 1.6e-25
Smith-Waterman score: 856; 56.2% identity (72.3% similar) in 260 aa overlap (111-365:7-249)

               90       100       110       120       130       140
pF1KB7 EPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSN
                                     ::.. ..  :.  :  . :.   : :   .
CCDS47                         MYKETVYSAFNLL--MHYPPPSGAGQHPQPQPPLHK
                                       10          20        30    

              150       160        170       180       190         
pF1KB7 KVPVVQPSHAVHPLTPLITYSDEHF-SPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPL
          . :: :.:  :.    :  ::: ::  ::.  :.:...:: . :   .::.  :: :
CCDS47 ---ANQPPHGVPQLS---LY--EHFNSP--HPTPAPADISQKQ-VHRPLQTPDLSGFYSL
              40             50          60         70        80   

     200       210          220       230       240       250      
pF1KB7 SPGGVGQITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKP
       . :..::.   ..::.:  .    : :: : ..::::::: :. :::    : .:   : 
CCDS47 TSGSMGQLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KT
            90       100       110        120       130            

        260       270       280       290       300       310      
pF1KB7 QHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREE
       : :.. :.: :.: :::::::::::::::::.:.::::::::::::::::::::::::::
CCDS47 QAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREE
     140       150       160       170       180       190         

        320       330       340       350       360        370     
pF1KB7 QAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTG-PRMTAAYI    
       ::::::::::::::::::::::::::::::::.:.::: :::.. :. ::          
CCDS47 QAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTETNWPRELKDGNGQES
     200       210       220       230       240       250         

CCDS47 LSMSSSSSPA
     260         

>>CCDS73198.1 TCF7L2 gene_id:6934|Hs108|chr10             (408 aa)
 initn: 1335 init1: 752 opt: 798  Z-score: 536.9  bits: 108.1 E(32554): 1.4e-23
Smith-Waterman score: 1397; 57.8% identity (71.4% similar) in 405 aa overlap (1-370:1-392)

               10        20        30        40        50        60
pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
       ::::.::::      .: :.::.: :::::. :.::  .: :  :.  ::::.:::::::
CCDS73 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEKS-SENSSAER--DLADVKSSLVNE
               10             20         30           40        50 

                70        80        90        100       110        
pF1KB7 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP
       ::    .:.  :. :.    .: ..::.::  ... :. ::::. ::: : .:  .::.:
CCDS73 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP
              60        70        80        90        100          

      120       130       140       150       160       170        
pF1KB7 NMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDV
       .... ::. ::::::   ::::::::::  : :::::::::::.:::.::. : :.:.::
CCDS73 DLTS-PYLPNGSLSPTA-RTSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADV
     110        120        130       140       150       160       

      180       190       200       210                            
pF1KB7 NSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW----------------FSH------
       . : :. : :  :::  .:::::: ::::  ::::                : :      
CCDS73 DPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTAL
       170       180       190       200       210       220       

                   220       230       240       250       260     
pF1KB7 -----------HMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQE
                  ::.:     ::::::::::::: ::::  ..:   .: . .....::.:
CCDS73 TVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEE
       230       240       250       260       270       280       

         270       280       290       300       310       320     
pF1KB7 PKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR
        :.:::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
CCDS73 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR
       290       300       310       320       330       340       

         330       340       350       360       370               
pF1KB7 KERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI              
       :::::::::::::::::::::::::::.:    ..:      :.:               
CCDS73 KERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSAFATYKVKAAASAHPLQMEA
       350       360       370       380       390       400       

CCDS73 Y
        

>>CCDS53577.1 TCF7L2 gene_id:6934|Hs108|chr10             (602 aa)
 initn: 1406 init1: 752 opt: 801  Z-score: 536.7  bits: 108.7 E(32554): 1.4e-23
Smith-Waterman score: 1131; 50.4% identity (62.6% similar) in 401 aa overlap (57-365:48-445)

         30        40        50        60         70        80     
pF1KB7 KDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESEIIP-ASNGHEVARQAQTSQEPYHD
                                     ::::::    .:.  :. :.    .: ..:
CCDS53 LISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSESFRD
        20        30        40        50        60        70       

          90        100       110       120       130              
pF1KB7 KAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSP-----------
       :.::  ... :. ::::. ::: : .:  .::.:.... ::. ::::::           
CCDS53 KSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIPDLTS-PYLPNGSLSPTARTLHFQSGS
        80        90        100        110        120       130    

                                                        140        
pF1KB7 -------------------------------------------PIPR--TSNKVPVVQPS
                                                  : :   .::::::::  
CCDS53 THYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHP
          140       150       160       170       180       190    

      150       160       170       180       190       200        
pF1KB7 HAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQIT
       : :::::::::::.:::.::. : :.:.::. : :. : :  :::  .:::::: :::: 
CCDS53 HHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIP
          200       210       220       230       240       250    

      210                                        220       230     
pF1KB7 PPLGW----------------FSH-----------------HMIPGPPGPHTTGIPHPAI
        ::::                : :                 ::.:     ::::::::::
CCDS53 HPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAI
          260       270       280       290       300       310    

         240       250       260       270       280       290     
pF1KB7 VTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTL
       ::: ::::  ..:   .: . .....::.: :.:::::::::::::::::::.:::::::
CCDS53 VTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTL
          320       330       340       350       360       370    

         300       310       320       330       340       350     
pF1KB7 KESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: 
CCDS53 KESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQ
          380       390       400       410       420       430    

          360       370                                            
pF1KB7 Q-ESASGTGPRMTAAYI                                           
         :. ... :.                                                 
CCDS53 PGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPP
          440       450       460       470       480       490    




371 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 10:52:40 2016 done: Tue Nov  8 10:52:41 2016
 Total Scan time:  3.030 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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