FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7666, 371 aa 1>>>pF1KB7666 371 - 371 aa - 371 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.5977+/-0.000371; mu= -1.6759+/- 0.023 mean_var=305.0862+/-63.183, 0's: 0 Z-trim(122.5): 146 B-trim: 494 in 2/59 Lambda= 0.073428 statistics sampled from 40584 (40736) to 40584 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.478), width: 16 Scan time: 8.210 The best scores are: opt bits E(85289) NP_001124185 (OMIM: 153245) lymphoid enhancer-bind ( 371) 2609 289.5 8.3e-78 NP_001124186 (OMIM: 153245) lymphoid enhancer-bind ( 386) 2546 282.9 8.7e-76 NP_001159591 (OMIM: 153245) lymphoid enhancer-bind ( 303) 2128 238.5 1.6e-62 XP_005263105 (OMIM: 153245) PREDICTED: lymphoid en ( 318) 2065 231.8 1.7e-60 NP_057353 (OMIM: 153245) lymphoid enhancer-binding ( 399) 1524 174.6 3.5e-43 XP_005263103 (OMIM: 153245) PREDICTED: lymphoid en ( 414) 1524 174.6 3.6e-43 XP_006714296 (OMIM: 153245) PREDICTED: lymphoid en ( 299) 1058 125.1 2e-28 XP_005263104 (OMIM: 153245) PREDICTED: lymphoid en ( 346) 1043 123.6 6.8e-28 NP_003193 (OMIM: 189908) transcription factor 7 is ( 384) 1042 123.5 7.9e-28 XP_006714742 (OMIM: 189908) PREDICTED: transcripti ( 429) 1039 123.3 1.1e-27 XP_006714747 (OMIM: 189908) PREDICTED: transcripti ( 365) 1032 122.4 1.6e-27 NP_998813 (OMIM: 189908) transcription factor 7 is ( 269) 851 103.1 7.6e-22 NP_963963 (OMIM: 189908) transcription factor 7 is ( 269) 851 103.1 7.6e-22 XP_011541914 (OMIM: 189908) PREDICTED: transcripti ( 244) 848 102.8 8.8e-22 NP_963965 (OMIM: 189908) transcription factor 7 is ( 268) 848 102.8 9.4e-22 NP_001128323 (OMIM: 189908) transcription factor 7 ( 269) 848 102.8 9.5e-22 XP_006714749 (OMIM: 189908) PREDICTED: transcripti ( 314) 848 102.9 1.1e-21 XP_011541911 (OMIM: 189908) PREDICTED: transcripti ( 289) 845 102.5 1.2e-21 NP_001185460 (OMIM: 125853,602228) transcription f ( 465) 805 98.5 3.3e-20 NP_001139758 (OMIM: 125853,602228) transcription f ( 442) 800 98.0 4.6e-20 NP_001185459 (OMIM: 125853,602228) transcription f ( 408) 798 97.7 5e-20 XP_016872082 (OMIM: 125853,602228) PREDICTED: tran ( 602) 801 98.2 5.3e-20 NP_001139746 (OMIM: 125853,602228) transcription f ( 602) 801 98.2 5.3e-20 XP_005270153 (OMIM: 125853,602228) PREDICTED: tran ( 482) 798 97.8 5.6e-20 XP_005270161 (OMIM: 125853,602228) PREDICTED: tran ( 438) 795 97.4 6.5e-20 XP_005270141 (OMIM: 125853,602228) PREDICTED: tran ( 619) 798 97.9 6.7e-20 XP_016872081 (OMIM: 125853,602228) PREDICTED: tran ( 619) 798 97.9 6.7e-20 XP_005270159 (OMIM: 125853,602228) PREDICTED: tran ( 461) 795 97.4 6.8e-20 XP_005270160 (OMIM: 125853,602228) PREDICTED: tran ( 447) 794 97.3 7.1e-20 NP_001139757 (OMIM: 125853,602228) transcription f ( 579) 796 97.6 7.4e-20 NP_001185455 (OMIM: 125853,602228) transcription f ( 579) 796 97.6 7.4e-20 NP_001185457 (OMIM: 125853,602228) transcription f ( 459) 793 97.2 7.8e-20 NP_001185458 (OMIM: 125853,602228) transcription f ( 459) 793 97.2 7.8e-20 XP_005270157 (OMIM: 125853,602228) PREDICTED: tran ( 470) 793 97.2 8e-20 XP_016872080 (OMIM: 125853,602228) PREDICTED: tran ( 620) 795 97.6 8.3e-20 XP_011538413 (OMIM: 125853,602228) PREDICTED: tran ( 596) 793 97.3 9.4e-20 NP_110383 (OMIM: 125853,602228) transcription fact ( 596) 793 97.3 9.4e-20 NP_001139755 (OMIM: 125853,602228) transcription f ( 489) 791 97.0 9.5e-20 XP_016872084 (OMIM: 125853,602228) PREDICTED: tran ( 513) 791 97.1 9.8e-20 NP_001185456 (OMIM: 125853,602228) transcription f ( 455) 788 96.7 1.1e-19 NP_001139756 (OMIM: 125853,602228) transcription f ( 455) 788 96.7 1.1e-19 XP_005270146 (OMIM: 125853,602228) PREDICTED: tran ( 584) 790 97.0 1.2e-19 XP_016872085 (OMIM: 125853,602228) PREDICTED: tran ( 478) 788 96.7 1.2e-19 XP_005270158 (OMIM: 125853,602228) PREDICTED: tran ( 464) 787 96.6 1.2e-19 XP_005270152 (OMIM: 125853,602228) PREDICTED: tran ( 518) 788 96.8 1.2e-19 NP_001185454 (OMIM: 125853,602228) transcription f ( 476) 787 96.6 1.2e-19 XP_005270142 (OMIM: 125853,602228) PREDICTED: tran ( 607) 789 96.9 1.3e-19 XP_005270145 (OMIM: 125853,602228) PREDICTED: tran ( 592) 788 96.8 1.4e-19 XP_011538412 (OMIM: 125853,602228) PREDICTED: tran ( 640) 788 96.8 1.4e-19 XP_016872076 (OMIM: 125853,602228) PREDICTED: tran ( 663) 788 96.9 1.5e-19 >>NP_001124185 (OMIM: 153245) lymphoid enhancer-binding (371 aa) initn: 2609 init1: 2609 opt: 2609 Z-score: 1517.9 bits: 289.5 E(85289): 8.3e-78 Smith-Waterman score: 2609; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371) 10 20 30 40 50 60 pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 310 320 330 340 350 360 370 pF1KB7 GTGPRMTAAYI ::::::::::: NP_001 GTGPRMTAAYI 370 >>NP_001124186 (OMIM: 153245) lymphoid enhancer-binding (386 aa) initn: 2544 init1: 2544 opt: 2546 Z-score: 1481.6 bits: 282.9 E(85289): 8.7e-76 Smith-Waterman score: 2546; 99.5% identity (99.5% similar) in 365 aa overlap (1-365:1-364) 10 20 30 40 50 60 pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 310 320 330 340 350 360 370 pF1KB7 GTGPRMTAAYI : : : NP_001 G-GKRSSFPTCKAKAATPGPLLEMEAC 370 380 >>NP_001159591 (OMIM: 153245) lymphoid enhancer-binding (303 aa) initn: 2128 init1: 2128 opt: 2128 Z-score: 1243.6 bits: 238.5 E(85289): 1.6e-62 Smith-Waterman score: 2128; 100.0% identity (100.0% similar) in 301 aa overlap (71-371:3-303) 50 60 70 80 90 100 pF1KB7 ISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGG :::::::::::::::::::::::::::::: NP_001 MAEVARQAQTSQEPYHDKAREHPDDGKHPDGG 10 20 30 110 120 130 140 150 160 pF1KB7 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB7 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIP 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB7 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 220 230 240 250 260 270 350 360 370 pF1KB7 RDNYGKKKKRKREKLQESASGTGPRMTAAYI ::::::::::::::::::::::::::::::: NP_001 RDNYGKKKKRKREKLQESASGTGPRMTAAYI 280 290 300 >>XP_005263105 (OMIM: 153245) PREDICTED: lymphoid enhanc (318 aa) initn: 2063 init1: 2063 opt: 2065 Z-score: 1207.3 bits: 231.8 E(85289): 1.7e-60 Smith-Waterman score: 2065; 99.3% identity (99.3% similar) in 295 aa overlap (71-365:3-296) 50 60 70 80 90 100 pF1KB7 ISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGG :::::::::::::::::::::::::::::: XP_005 MAEVARQAQTSQEPYHDKAREHPDDGKHPDGG 10 20 30 110 120 130 140 150 160 pF1KB7 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB7 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIP 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB7 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 220 230 240 250 260 270 350 360 370 pF1KB7 RDNYGKKKKRKREKLQESASGTGPRMTAAYI ::::::::::::::::::::: : : XP_005 RDNYGKKKKRKREKLQESASG-GKRSSFPTCKAKAATPGPLLEMEAC 280 290 300 310 >>NP_057353 (OMIM: 153245) lymphoid enhancer-binding fac (399 aa) initn: 1514 init1: 1514 opt: 1524 Z-score: 896.3 bits: 174.6 E(85289): 3.5e-43 Smith-Waterman score: 2543; 93.0% identity (93.0% similar) in 399 aa overlap (1-371:1-399) 10 20 30 40 50 60 pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 130 140 150 160 170 180 190 200 210 pF1KB7 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW--------------------------- ::::::::::::::::::::::::::::::::: NP_057 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 -FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 310 320 330 340 350 360 340 350 360 370 pF1KB7 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI ::::::::::::::::::::::::::::::::::::::: NP_057 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI 370 380 390 >>XP_005263103 (OMIM: 153245) PREDICTED: lymphoid enhanc (414 aa) initn: 1514 init1: 1514 opt: 1524 Z-score: 896.1 bits: 174.6 E(85289): 3.6e-43 Smith-Waterman score: 2480; 92.4% identity (92.4% similar) in 393 aa overlap (1-365:1-392) 10 20 30 40 50 60 pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 130 140 150 160 170 180 190 200 210 pF1KB7 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW--------------------------- ::::::::::::::::::::::::::::::::: XP_005 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 -FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 310 320 330 340 350 360 340 350 360 370 pF1KB7 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI ::::::::::::::::::::::::::::: : : XP_005 QLYPGWSARDNYGKKKKRKREKLQESASG-GKRSSFPTCKAKAATPGPLLEMEAC 370 380 390 400 410 >>XP_006714296 (OMIM: 153245) PREDICTED: lymphoid enhanc (299 aa) initn: 1031 init1: 1031 opt: 1058 Z-score: 631.1 bits: 125.1 E(85289): 2e-28 Smith-Waterman score: 1679; 89.2% identity (89.2% similar) in 278 aa overlap (116-365:1-277) 90 100 110 120 130 140 pF1KB7 KAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVV :::::::::::::::::::::::::::::: XP_006 MMPNMNNDPYMSNGSLSPPIPRTSNKVPVV 10 20 30 150 160 170 180 190 200 pF1KB7 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 40 50 60 70 80 90 210 220 230 pF1KB7 QITPPLGW----------------------------FSHHMIPGPPGPHTTGIPHPAIVT :::::::: :::::::::::::::::::::::: XP_006 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB7 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB7 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 220 230 240 250 260 270 360 370 pF1KB7 SASGTGPRMTAAYI :::: : : XP_006 SASG-GKRSSFPTCKAKAATPGPLLEMEAC 280 290 >>XP_005263104 (OMIM: 153245) PREDICTED: lymphoid enhanc (346 aa) initn: 1033 init1: 1033 opt: 1043 Z-score: 621.7 bits: 123.6 E(85289): 6.8e-28 Smith-Waterman score: 1999; 90.7% identity (90.7% similar) in 323 aa overlap (71-365:3-324) 50 60 70 80 90 100 pF1KB7 ISHPEEEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGG :::::::::::::::::::::::::::::: XP_005 MAEVARQAQTSQEPYHDKAREHPDDGKHPDGG 10 20 30 110 120 130 140 150 160 pF1KB7 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITY 40 50 60 70 80 90 170 180 190 200 210 pF1KB7 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYP 100 110 120 130 140 150 220 230 240 250 pF1KB7 ---------------------FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLM ::::::::::::::::::::::::::::::::::::::: XP_005 ITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLM 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB7 HVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHAL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB7 SREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI ::::::::::::::::::::::::::::::::::::::::::::::::: : : XP_005 SREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASG-GKRSSFPTCK 280 290 300 310 320 330 XP_005 AKAATPGPLLEMEAC 340 >>NP_003193 (OMIM: 189908) transcription factor 7 isofor (384 aa) initn: 867 init1: 568 opt: 1042 Z-score: 620.6 bits: 123.5 E(85289): 7.9e-28 Smith-Waterman score: 1062; 50.3% identity (68.1% similar) in 386 aa overlap (1-365:1-362) 10 20 30 40 50 60 pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE ::::..::::.:: .: : ::.. :.:::. : .: . ::. :::..::::::: NP_003 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE 10 20 30 40 50 70 80 90 100 pF1KB7 SEI------IPASNGH--------EVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN :: ::. : :. . ...:. . :: : .:: : :. .:.:. NP_003 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE . . ::.. .. :. : . :. : : . . :: :.: :. : : NP_003 E----TVYSAFNLL--MHYPPPSGAGQHPQPQPPLHK---ANQPPHGVPQLS---LY--E 120 130 140 150 160 170 180 190 200 210 pF1KB7 HF-SPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMI--- :: :: ::. :.:...:: . : .::. :: :. :..::. ..::.: . NP_003 HFNSP--HPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLG 170 180 190 200 210 220 220 230 240 250 260 270 pF1KB7 PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFM : :: : ..::::::: :. ::: : .: : : :.. :.: :.: ::::::::: NP_003 SGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFM 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 LYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWS ::::::::.:.::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWS 280 290 300 310 320 330 340 350 360 370 pF1KB7 ARDNYGKKKKRKREKLQESASGTGPRMTAAYI :::::::::.:.::: :::..: : : NP_003 ARDNYGKKKRRSREKHQESTTG-GKRNAFGTYPEKAAAPAPFLPMTVL 340 350 360 370 380 >>XP_006714742 (OMIM: 189908) PREDICTED: transcription f (429 aa) initn: 865 init1: 566 opt: 1039 Z-score: 618.3 bits: 123.3 E(85289): 1.1e-27 Smith-Waterman score: 1059; 49.9% identity (68.0% similar) in 387 aa overlap (1-365:1-364) 10 20 30 40 50 60 pF1KB7 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE ::::..::::.:: .: : ::.. :.:::. : .: . ::. :::..::::::: XP_006 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE 10 20 30 40 50 70 80 90 100 pF1KB7 SEI------IPASNGH--------EVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN :: ::. : :. . ...:. . :: : .:: : :. .:.:. XP_006 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE . . ::.. .. :. : . :. : : . . :: :.: :. : : XP_006 E----TVYSAFNLL--MHYPPPSGAGQHPQPQPPLHK---ANQPPHGVPQLS---LY--E 120 130 140 150 160 170 180 190 200 210 pF1KB7 HF-SPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMI--- :: :: ::. :.:...:: . : .::. :: :. :..::. ..::.: . XP_006 HFNSP--HPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLG 170 180 190 200 210 220 220 230 240 250 260 270 pF1KB7 PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFM : :: : ..::::::: :. ::: : .: : : :.. :.: :.: ::::::::: XP_006 SGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFM 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 LYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWS ::::::::.:.::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWS 280 290 300 310 320 330 340 350 360 370 pF1KB7 ARDNYGKKKKRKREKLQESASGTG-PRMTAAYI :::::::::.:.::: :::.. : :. XP_006 ARDNYGKKKRRSREKHQESTTDPGSPKKCRARFGLNQQTDWCGPCRWVCPHHRSPFALSC 340 350 360 370 380 390 371 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 10:52:41 2016 done: Tue Nov 8 10:52:42 2016 Total Scan time: 8.210 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]