Result of FASTA (omim) for
pF1KB7676
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7676, 406 aa
1>>>pF1KB7676 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6209+/-0.000419; mu= 20.7914+/- 0.027
mean_var=246.1622+/-52.091, 0's: 0 Z-trim(119.1): 335 B-trim: 0 in 0/56
Lambda= 0.081745
statistics sampled from 32381 (32832) to 32381 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.385), width: 16
Scan time: 7.600
The best scores are: opt bits E(85289)
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 2741 336.4 7.8e-92
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 2134 264.6 2.5e-70
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 1029 134.3 4.3e-31
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 1029 134.4 4.5e-31
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 1029 134.4 4.6e-31
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 1029 134.4 4.6e-31
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 1029 134.5 4.7e-31
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 461 67.4 6.5e-11
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 461 67.5 6.8e-11
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 459 67.2 7.8e-11
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 461 67.7 7.8e-11
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 459 67.2 7.9e-11
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 459 67.2 8e-11
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230) 451 65.9 1.2e-10
NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349) 443 65.2 2.8e-10
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 442 65.2 3.2e-10
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 430 63.1 5.6e-10
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 430 63.1 5.6e-10
NP_001230541 (OMIM: 180386) LIM domain only protei ( 163) 430 63.1 5.7e-10
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 433 64.2 6.8e-10
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 425 62.4 8.1e-10
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 425 62.4 8.1e-10
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 425 62.4 8.1e-10
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 425 62.4 8.1e-10
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 425 62.4 8.1e-10
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 425 62.4 8.1e-10
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 425 62.4 8.1e-10
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 425 62.4 8.1e-10
NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 425 62.5 8.4e-10
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 424 62.3 8.8e-10
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 424 62.3 8.8e-10
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 424 62.5 1e-09
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 417 61.6 1.7e-09
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 417 61.6 1.7e-09
XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279) 398 59.8 9.9e-09
XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 348 53.4 4.6e-07
XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
NP_001135788 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 348 53.4 4.6e-07
XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 53.4 4.6e-07
NP_005565 (OMIM: 180385) rhombotin-2 isoform 1 [Ho ( 227) 348 53.7 5.4e-07
NP_002305 (OMIM: 601329) LIM domain kinase 1 isofo ( 647) 337 53.2 2.1e-06
XP_016871746 (OMIM: 602330) PREDICTED: actin-bindi ( 522) 321 51.2 7.2e-06
XP_016871736 (OMIM: 602330) PREDICTED: actin-bindi ( 619) 321 51.3 7.8e-06
XP_016871737 (OMIM: 602330) PREDICTED: actin-bindi ( 619) 321 51.3 7.8e-06
>>NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 [Ho (406 aa)
initn: 2741 init1: 2741 opt: 2741 Z-score: 1769.7 bits: 336.4 E(85289): 7.8e-92
Smith-Waterman score: 2741; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)
10 20 30 40 50 60
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 FNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 QKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELSNASLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELSNASLSP
310 320 330 340 350 360
370 380 390 400
pF1KB7 SSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
370 380 390 400
>>XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobox pr (314 aa)
initn: 2134 init1: 2134 opt: 2134 Z-score: 1383.7 bits: 264.6 E(85289): 2.5e-70
Smith-Waterman score: 2134; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311)
10 20 30 40 50 60
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 FNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 QKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELSNASLSP
:::::::::::
XP_006 QKTGLTKRVLQASL
310
>>XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobox pr (336 aa)
initn: 1422 init1: 924 opt: 1029 Z-score: 679.2 bits: 134.3 E(85289): 4.3e-31
Smith-Waterman score: 1565; 73.7% identity (87.2% similar) in 312 aa overlap (1-311:26-318)
10 20 30
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDR
::::..:: ...:...::.::.:.:: ..:
XP_005 MQTLQTPSPLRMKPASSRVSGPQEAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 GDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFS
: .. :: .: .. ::::::::::::::::::::::::.:::::::::: ::::::::.
XP_005 G-RDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFA
70 80 90 100 110
100 110 120 130 140 150
pF1KB7 KDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDH
:::::::::::::::::::::::::::::::::::::: ::::.::::.:::: ::::::
XP_005 KDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 FGMKDSLVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYN
::::::::::: :::.::::::: ....... ::::.::. :::.:
XP_005 FGMKDSLVYCRAHFETLLQGEYPPQLSYTEL--------AAKSGGLA--------LPYFN
180 190 200 210 220
220 230 240 250 260 270
pF1KB7 GVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQ-PYPSSQKTKRMRTSFK
:.::::::::::::::. :.:.. ::. .::::.:.:::::: ::: ::::::::::::
XP_005 GTGTVQKGRPRKRKSPALGVDIVNYNS--GCNENEADHLDRDQQPYPPSQKTKRMRTSFK
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB7 HHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVD
:::::::::::::::::::::::::::::::::::::
XP_005 HHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQGEQILGHYSQTSRRLKIP
290 300 310 320 330
340 350 360 370 380 390
pF1KB7 KSTDAALQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEP
>>XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobox pr (378 aa)
initn: 1824 init1: 930 opt: 1029 Z-score: 678.8 bits: 134.4 E(85289): 4.5e-31
Smith-Waterman score: 1891; 70.3% identity (85.5% similar) in 407 aa overlap (1-406:1-378)
10 20 30 40 50 60
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI
::::..:: ...:...::.::.:.:: ..: : .. :: .: .. ::::::::::
XP_016 MLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNG-RDAGMPPLSPEKPALCAGCGGKI
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL
::::::::::::::.:::::::::: ::::::::.:::::::::::::::::::::::::
XP_016 SDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH
::::::::::::: ::::.::::.:::: ::::::::::::::::: :::.::::::: .
XP_016 GISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 FNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY
......:: ::.::. :::.::.::::::::::::::. :.:.. :
XP_016 LSYTELAA--------KSGGLA--------LPYFNGTGTVQKGRPRKRKSPALGVDIVNY
180 190 200 210 220
250 260 270 280 290
pF1KB7 NAALSCNENDAEHLDRDQ-PYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
:. .::::.:.:::::: ::: :::::::::::::::::::::::::::::::::::::
XP_016 NS--GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELSNASLS
::::::::::::::::::::::::::::::: ::::. ..: :. :... ...:.
XP_016 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSL----PAPPSAD--SGALT
290 300 310 320 330
360 370 380 390 400
pF1KB7 PSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
: .: :::::::.::. .:.::: .:...:: :::::::::::
XP_016 PPGTATTLTDLTNPTI----TVVTSVTSNMDSHESGSPSQTTLTNLF
340 350 360 370
>>NP_001014434 (OMIM: 606066) LIM/homeobox protein Lhx9 (388 aa)
initn: 1824 init1: 930 opt: 1029 Z-score: 678.7 bits: 134.4 E(85289): 4.6e-31
Smith-Waterman score: 1891; 70.3% identity (85.5% similar) in 407 aa overlap (1-406:11-388)
10 20 30 40 50
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRA
::::..:: ...:...::.::.:.:: ..: : .. :: .: ..
NP_001 MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNG-RDAGMPPLSPEKP
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRF
::::::::::::::::::::::::.:::::::::: ::::::::.:::::::::::::::
NP_001 ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 SVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFE
::::::::::::::::::::::: ::::.::::.:::: ::::::::::::::::: :::
NP_001 SVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 ALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKS
.::::::: .......:: ::.::. :::.::.:::::::::::::
NP_001 TLLQGEYPPQLSYTELAA--------KSGGLA--------LPYFNGTGTVQKGRPRKRKS
180 190 200 210 220
240 250 260 270 280
pF1KB7 PGPGADLAAYNAALSCNENDAEHLDRDQ-PYPSSQKTKRMRTSFKHHQLRTMKSYFAINH
:. :.:.. ::. .::::.:.:::::: ::: :::::::::::::::::::::::::::
NP_001 PALGVDIVNYNS--GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINH
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 NPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGP
::::::::::::::::::::::::::::::::::::::::: ::::. ..: :. :
NP_001 NPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSL----PAPP
290 300 310 320 330
350 360 370 380 390 400
pF1KB7 ASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
... ...:.: .: :::::::.::. .:.::: .:...:: :::::::::::
NP_001 SAD--SGALTPPGTATTLTDLTNPTI----TVVTSVTSNMDSHESGSPSQTTLTNLF
340 350 360 370 380
>>NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 iso (397 aa)
initn: 1824 init1: 930 opt: 1029 Z-score: 678.6 bits: 134.4 E(85289): 4.6e-31
Smith-Waterman score: 1891; 70.3% identity (85.5% similar) in 407 aa overlap (1-406:20-397)
10 20 30 40
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETT
::::..:: ...:...::.::.:.:: ..: : ..
NP_064 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNG-RDAG
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 MPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIY
:: .: .. ::::::::::::::::::::::::.:::::::::: ::::::::.::::::
NP_064 MPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIY
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 CKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDS
:::::::::::::::::::::::::::::::: ::::.::::.:::: ::::::::::::
NP_064 CKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 LVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQ
::::: :::.::::::: .......:: ::.::. :::.::.::::
NP_064 LVYCRAHFETLLQGEYPPQLSYTELAA--------KSGGLA--------LPYFNGTGTVQ
180 190 200 210 220
230 240 250 260 270 280
pF1KB7 KGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQ-PYPSSQKTKRMRTSFKHHQLRT
::::::::::. :.:.. ::. .::::.:.:::::: ::: ::::::::::::::::::
NP_064 KGRPRKRKSPALGVDIVNYNS--GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 MKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAA
:::::::::::::::::::::::::::::::::::::::::::::::::: ::::. ..
NP_064 MKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTS
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 LQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQT
: :. :... ...:.: .: :::::::.::. .:.::: .:...:: :::::
NP_064 L----PAPPSAD--SGALTPPGTATTLTDLTNPTI----TVVTSVTSNMDSHESGSPSQT
350 360 370 380 390
pF1KB7 TLTNLF
::::::
NP_064 TLTNLF
>>XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobox pr (403 aa)
initn: 1824 init1: 930 opt: 1029 Z-score: 678.6 bits: 134.5 E(85289): 4.7e-31
Smith-Waterman score: 1891; 70.3% identity (85.5% similar) in 407 aa overlap (1-406:26-403)
10 20 30
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDR
::::..:: ...:...::.::.:.:: ..:
XP_011 MQTLQTPSPLRMKPASSRVSGPQEAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 GDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFS
: .. :: .: .. ::::::::::::::::::::::::.:::::::::: ::::::::.
XP_011 G-RDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFA
70 80 90 100 110
100 110 120 130 140 150
pF1KB7 KDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDH
:::::::::::::::::::::::::::::::::::::: ::::.::::.:::: ::::::
XP_011 KDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 FGMKDSLVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYN
::::::::::: :::.::::::: .......:: ::.::. :::.:
XP_011 FGMKDSLVYCRAHFETLLQGEYPPQLSYTELAA--------KSGGLA--------LPYFN
180 190 200 210 220
220 230 240 250 260 270
pF1KB7 GVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQ-PYPSSQKTKRMRTSFK
:.::::::::::::::. :.:.. ::. .::::.:.:::::: ::: ::::::::::::
XP_011 GTGTVQKGRPRKRKSPALGVDIVNYNS--GCNENEADHLDRDQQPYPPSQKTKRMRTSFK
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB7 HHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 HHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVD
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB7 KSTDAALQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEP
:. ..: :. :... ...:.: .: :::::::.::. .:.::: .:...::
XP_011 KADGTSL----PAPPSAD--SGALTPPGTATTLTDLTNPTI----TVVTSVTSNMDSHES
350 360 370 380 390
400
pF1KB7 HSPSQTTLTNLF
:::::::::::
XP_011 GSPSQTTLTNLF
400
>>NP_665804 (OMIM: 609481) insulin gene enhancer protein (359 aa)
initn: 448 init1: 255 opt: 461 Z-score: 316.9 bits: 67.4 E(85289): 6.5e-11
Smith-Waterman score: 596; 35.9% identity (59.8% similar) in 301 aa overlap (51-346:25-274)
30 40 50 60 70
pF1KB7 RAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKISDRYYL-LAVDKQWHMRCLK
:.:.:::..: :.. : .. : .:: :::
NP_665 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLK
10 20 30 40 50
80 90 100 110 120 130
pF1KB7 CCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLN
: ::. :. ::: .::. :::.:: : :.. .::.:..:.:.:..:::::: :::..
NP_665 CAECSQYLDETCTCFVRDGKTYCKRDYVRLFGI-KCAKCQVGFSSSDLVMRARDSVYHIE
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB7 CFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSA
:: :..:...: ::.:.... . :: ::. :::.. .:
NP_665 CFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLE---------------RAAAGSPRSP
120 130 140 150
200 210 220 230 240 250
pF1KB7 GLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQP
: :: : :: : : ::. .:.
NP_665 G-PLPGARGLHLPD-AGSGRQPALRPHVHKQ-----------------------------
160 170 180
260 270 280 290 300 310
pF1KB7 YPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARA
..:: :.:: ....::.:... .: : ::: .::.. :::. ::..::::: :
NP_665 ---TEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRC
190 200 210 220 230 240
320 330 340 350 360 370
pF1KB7 KFRRN--LLRQ--ENTGVDKSTDAALQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTL
: ... :..: .. ::.. .: ::::
NP_665 KDKKKSILMKQLQQQQHSDKTSLQGL-TGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKA
250 260 270 280 290 300
380 390 400
pF1KB7 PTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
NP_665 LSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET
310 320 330 340 350
>>NP_055379 (OMIM: 221750,600577) LIM/homeobox protein L (402 aa)
initn: 521 init1: 192 opt: 461 Z-score: 316.5 bits: 67.5 E(85289): 6.8e-11
Smith-Waterman score: 470; 28.6% identity (55.3% similar) in 398 aa overlap (22-400:3-377)
10 20 30 40 50
pF1KB7 MLFHSLSGPEVHGVIDEMDRRAKSE-APAISSAIDRGDTETTMPSISSD---RAALCAGC
:..: .:: :: :: .. . .: . :::::
NP_055 MEARGELGPARESA--GGDLLLALLARRADLRREIPLCAGC
10 20 30
60 70 80 90 100 110
pF1KB7 GGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCA
.: ::. : :.:..:: .:::: .:. : . :::. :.:::.:...::.. .::
NP_055 DQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFGT-KCA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 RCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFG-MKDSLVYCRLHFEALLQG
:.::: ...: ::.:.::::.::.:..:...:.:::.: :.:: . :. .:. :
NP_055 ACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 EYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGA
: : .. .. .: . ::: :: . . :.. : :
NP_055 EAEATAKRPRTTITAKQLETLKSA--------------YNTSPKPAR-HVREQLSSETGL
160 170 180 190 200
240 250 260 270 280
pF1KB7 DLAAYNAALSCNENDAEHLDRDQ------PYPSSQKTKRMRTSFKHHQLRTMKSYFAINH
:. . .. .. . ..: .: : ..: .: .. . ... .. :
NP_055 DMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVS
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB7 NPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDA-ALQTGTPSG
:: .: ... .:: . . .: . . . :. :. . :. :.: :
NP_055 FPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYG
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB7 -PASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGN------LEGHEPHSPSQTT
: : . :: :. : :..:. : .. : ...::. : :. : : .:
NP_055 VPPSPAAPQSL-PGPQPL-LSSLVYPDT-SLGLVPSGAPGGPPPMRVLAGNGPSSDLSTG
330 340 350 360 370
pF1KB7 LTNLF
NP_055 SSGGYPDFPASPASWLDEVDHAQF
380 390 400
>>XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/home (373 aa)
initn: 521 init1: 192 opt: 459 Z-score: 315.5 bits: 67.2 E(85289): 7.8e-11
Smith-Waterman score: 468; 29.0% identity (56.2% similar) in 365 aa overlap (52-400:6-348)
30 40 50 60 70 80
pF1KB7 AKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCC
::::: .: ::. : :.:..:: .::::
XP_016 MQQIPLCAGCDQHILDRFILKALDRHWHSKCLKCS
10 20 30
90 100 110 120 130 140
pF1KB7 ECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCF
.:. : . :::. :.:::.:...::.. .:: :.::: ...: ::.:.::::.::
XP_016 DCHTPLAER--CFSRGESVYCKDDFFKRFGT-KCAACQLGIPPTQVVRRAQDFVYHLHCF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB7 TCTTCNKMLTTGDHFG-MKDSLVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAG
.:..:...:.:::.: :.:: . :. .:. : : : .. .. .: . :::
XP_016 ACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSA-
100 110 120 130 140 150
210 220 230 240 250
pF1KB7 LGAAGANPLGLPYYNGVGTVQKGRP-RKRKSPGPGADLAAYNAALSCNENDAEHLDRDQ-
:: . . .: :.. : : :. . .. .. . ..: .:
XP_016 -------------YNT--SPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAG
160 170 180 190
260 270 280 290 300 310
pF1KB7 -----PYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVW
: ..: .: .. . ... .. : :: .: ... .:: . .
XP_016 RQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPT
200 210 220 230 240 250
320 330 340 350 360 370
pF1KB7 FQNARAKFRRNLLRQENTGVDKSTDA-ALQTGTPSG-PASELSNASLSPSSTPTTLTDLT
.: . . . :. :. . :. :.: : : : . :: :. : :..:.
XP_016 QALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSL-PGPQPL-LSSLV
260 270 280 290 300 310
380 390 400
pF1KB7 SPTLPTVTSVLTSVPGN------LEGHEPHSPSQTTLTNLF
: .. : ...::. : :. : : .:
XP_016 YPDT-SLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
320 330 340 350 360 370
406 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:49:24 2016 done: Sat Nov 5 17:49:25 2016
Total Scan time: 7.600 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]