FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7688, 410 aa 1>>>pF1KB7688 410 - 410 aa - 410 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1853+/-0.000762; mu= 14.1900+/- 0.047 mean_var=96.2441+/-18.994, 0's: 0 Z-trim(110.7): 22 B-trim: 0 in 0/53 Lambda= 0.130734 statistics sampled from 11797 (11810) to 11797 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.363), width: 16 Scan time: 2.950 The best scores are: opt bits E(32554) CCDS9538.1 TFDP1 gene_id:7027|Hs108|chr13 ( 410) 2680 515.4 3.8e-146 CCDS14636.2 TFDP3 gene_id:51270|Hs108|chrX ( 405) 1894 367.2 1.6e-101 CCDS54650.1 TFDP2 gene_id:7029|Hs108|chr3 ( 446) 1351 264.8 1.2e-70 CCDS43159.1 TFDP2 gene_id:7029|Hs108|chr3 ( 386) 1336 261.9 7.3e-70 CCDS54648.1 TFDP2 gene_id:7029|Hs108|chr3 ( 418) 1334 261.6 1e-69 CCDS54649.1 TFDP2 gene_id:7029|Hs108|chr3 ( 349) 1320 258.9 5.5e-69 CCDS54647.1 TFDP2 gene_id:7029|Hs108|chr3 ( 310) 1208 237.7 1.1e-62 >>CCDS9538.1 TFDP1 gene_id:7027|Hs108|chr13 (410 aa) initn: 2680 init1: 2680 opt: 2680 Z-score: 2737.3 bits: 515.4 E(32554): 3.8e-146 Smith-Waterman score: 2680; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KB7 MAKDAGLIEANGELKVFIDQNLSPGKGVVSLVAVHPSTVNPLGKQLLPKTFGQSNVNIAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 MAKDAGLIEANGELKVFIDQNLSPGKGVVSLVAVHPSTVNPLGKQLLPKTFGQSNVNIAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QVVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAGKRNRKGEKNGKGLRHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 QVVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAGKRNRKGEKNGKGLRHFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 MKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 MKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 IISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 RHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 KRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVFITTAGSTSNGTRFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 KRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVFITTAGSTSNGTRFS 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 ASDLTNGADGMLATSSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDEDD :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 ASDLTNGADGMLATSSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDEDD 370 380 390 400 410 >>CCDS14636.2 TFDP3 gene_id:51270|Hs108|chrX (405 aa) initn: 1702 init1: 1640 opt: 1894 Z-score: 1936.2 bits: 367.2 E(32554): 1.6e-101 Smith-Waterman score: 1894; 75.2% identity (87.3% similar) in 411 aa overlap (1-410:1-405) 10 20 30 40 50 60 pF1KB7 MAKDAGLIEANGELKVFIDQNLSPGKGVVSLVAVHPSTVNPLGKQLLPKTFGQSNVNIAQ ::: ..: ::: ::::..:.: . :::: ::::::::::::::::::.::: : CCDS14 MAKYVSLTEANEELKVLMDENQTSRP-----VAVHTSTVNPLGKQLLPKTFGQSSVNIDQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QVVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAGKRNRKGEKNGKGLRHFS ::::: :::::::: :::::. :::::::::: : ::: ::..:::::::: :: ..: CCDS14 QVVIGMPQRPAASNIPVVGSPNPPSTHFASQNQHSYSSPPWAGQHNRKGEKNGMGLCRLS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 MKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMN ::: : :::::::: .::. ::::.: ::.:: ::::::: :::.::.::::::::::: CCDS14 MKVWETVQRKGTTSCQEVVGELVAKFRAASNHASPNESAYDVKNIKRRTYDALNVLMAMN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 IISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRN :::.:::.:::::: :::::.::::.::::.::::::::::.::.:::::::::::: :: CCDS14 IISREKKKIKWIGLTTNSAQNCQNLRVERQKRLERIKQKQSELQQLILQQIAFKNLVLRN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 RHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVL ...:.:.:. : ::::::.::::...::::::.::::.:: ::::.:...:::::: ::: CCDS14 QYVEEQVSQRPLPNSVIHVPFIIISSSKKTVINCSISDDKSEYLFKFNSSFEIHDDTEVL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 KRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVFITTAGSTSNGTRFS :::. ::::::::::::::::.::::::::::::::::: :::: ::::: :::: .: CCDS14 MWMGMTFGLESGSCSAEDLKMARNLVPKALEPYVTEMAQGTFGGVF-TTAGSRSNGTWLS 300 310 320 330 340 350 370 380 390 400 410 pF1KB7 ASDLTNGADGMLATSSNGSQYSGSRVETP-VSYVGEDDEEDDDFNENDEDD :::::: : :::::::.:::::::::::: : :.:..:::..:::::: CCDS14 ASDLTNIAIGMLATSSGGSQYSGSRVETPAVEEEEEEDNNDDDLSENDEDD 360 370 380 390 400 >>CCDS54650.1 TFDP2 gene_id:7029|Hs108|chr3 (446 aa) initn: 1413 init1: 1028 opt: 1351 Z-score: 1382.1 bits: 264.8 E(32554): 1.2e-70 Smith-Waterman score: 1608; 59.6% identity (79.1% similar) in 446 aa overlap (2-408:3-446) 10 20 30 40 50 pF1KB7 MAKDAGLIEANGELKVFIDQNLSPGKGVVSLVAVHPSTVNPLGKQLLPKTFGQSNVNIA ::..:: .:.:.. :::::::: :: .:.:: :..: : .::::.: :::.. CCDS54 MTAKNVGLTSTNAEVRGFIDQNLSPTKGNISFVAFPVSNTNSPTK-ILPKTLGPINVNVG 10 20 30 40 50 60 70 80 90 100 pF1KB7 QQVVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAG---------------- :..:.:::: ..:.....:::.::. ...:.. .... : : CCDS54 PQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSES 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 KRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQK ::..::.:::::::::::::::::::::::::::::::::.::. ..:: : .:::::: CCDS54 KRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNH-LAADSAYDQK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 NIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQL :::::::::::::::::::::::::::::::::::::::::::.:.:::.::::::..:: CCDS54 NIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 QELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEY :::.::::::::::::::. ::: . :: ::.:.:::::.:::.:::::::::.::::: CCDS54 QELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 LFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTV- ::::::::::::::::::::::. :::::.:: ::::.:.:::::::: :.:... : CCDS54 LFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSW 300 310 320 330 340 350 350 360 370 380 pF1KB7 --GGVFITTAGSTSN-----GTRFSASDLTNG----ADGMLAT-----------SSNGSQ :...... :.:: :. . :....: :. ::: :: .:. CCDS54 LNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASH 360 370 380 390 400 410 390 400 410 pF1KB7 YSGSRVETPVSYVGEDDEEDDDFNENDEDD : :: ::: :. ::.:.:.. . . : CCDS54 CSESRGETPCSFNDEDEEDDEEDSSSPE 420 430 440 >>CCDS43159.1 TFDP2 gene_id:7029|Hs108|chr3 (386 aa) initn: 1405 init1: 1308 opt: 1336 Z-score: 1367.7 bits: 261.9 E(32554): 7.3e-70 Smith-Waterman score: 1434; 60.4% identity (79.8% similar) in 386 aa overlap (62-408:1-386) 40 50 60 70 80 90 pF1KB7 VAVHPSTVNPLGKQLLPKTFGQSNVNIAQQVVIGTPQRPAASNTLVVGSPHTPSTHFASQ ..:.:::: ..:.....:::.::. ...: CCDS43 MIISTPQRLTSSGSVLIGSPYTPAPAMVTQ 10 20 30 100 110 120 130 pF1KB7 NQPSDSSPWSAG----------------KRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSY .. .... : : ::..::.::::::::::::::::::::::::: CCDS43 THIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSY 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB7 NEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLP ::::::::.::. ..::. . .::::::::::::::::::::::::::::::::::::: CCDS43 NEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLP 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB7 TNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNS :::::::::::.:.:::.::::::..:::::.::::::::::::::. ::: . :: :: CCDS43 TNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNS 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB7 VIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCS .:.:::::.:::.:::::::::.:::::::::::::::::::::::::::. :::::.:: CCDS43 TIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCS 220 230 240 250 260 270 320 330 340 350 360 pF1KB7 AEDLKMARSLVPKALEPYVTEMAQGTV---GGVFITTAGSTSN-----GTRFSASDLTNG ::::.:.:::::::: :.:... : :...... :.:: :. . :....: CCDS43 LEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQG 280 290 300 310 320 330 370 380 390 400 410 pF1KB7 ----ADGMLAT-----------SSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDEDD :. ::: :: .:. : :: ::: :. ::.:.:.. . . : CCDS43 LCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE 340 350 360 370 380 >>CCDS54648.1 TFDP2 gene_id:7029|Hs108|chr3 (418 aa) initn: 1245 init1: 1028 opt: 1334 Z-score: 1365.2 bits: 261.6 E(32554): 1e-69 Smith-Waterman score: 1435; 59.8% identity (79.9% similar) in 393 aa overlap (55-408:27-418) 30 40 50 60 70 80 pF1KB7 GKGVVSLVAVHPSTVNPLGKQLLPKTFGQSNVNIAQQVVIGTPQRPAASNTLVVGSPHTP ... .....:.:::: ..:.....:::.:: CCDS54 MQPEGIIFEAENKPSPGTESAGTFILDLSATSRTIISTPQRLTSSGSVLIGSPYTP 10 20 30 40 50 90 100 110 120 pF1KB7 STHFASQNQPSDSSPWSAG----------------KRNRKGEKNGKGLRHFSMKVCEKVQ . ...:.. .... : : ::..::.:::::::::::::::::: CCDS54 APAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 RKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKE :::::::::::::::.::. ..:: : .::::::::::::::::::::::::::::::: CCDS54 RKGTTSYNEVADELVSEFTNSNNH-LAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 IKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQAS ::::::::::::::::::.:.:::.::::::..:::::.::::::::::::::. ::: . CCDS54 IKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 RPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACG :: ::.:.:::::.:::.:::::::::.:::::::::::::::::::::::::::. : CCDS54 GPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LESGSCSAEDLKMARSLVPKALEPYVTEMAQGTV---GGVFITTAGSTSN-----GTRFS ::::.:: ::::.:.:::::::: :.:... : :...... :.:: :. . CCDS54 LESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLP 300 310 320 330 340 350 370 380 390 400 pF1KB7 ASDLTNG----ADGMLAT-----------SSNGSQYSGSRVETPVSYVGEDDEEDDDFNE :....: :. ::: :: .:. : :: ::: :. ::.:.:.. . CCDS54 QSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSS 360 370 380 390 400 410 410 pF1KB7 NDEDD . : CCDS54 SPE >>CCDS54649.1 TFDP2 gene_id:7029|Hs108|chr3 (349 aa) initn: 1125 init1: 1028 opt: 1320 Z-score: 1352.0 bits: 258.9 E(32554): 5.5e-69 Smith-Waterman score: 1365; 66.8% identity (82.9% similar) in 334 aa overlap (98-408:17-349) 70 80 90 100 110 120 pF1KB7 QRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAGKRNRKGEKNGKGLRHFSMKVCEKV : .: .::..::.::::::::::::::::: CCDS54 MLDPKCDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKV 10 20 30 40 130 140 150 160 170 180 pF1KB7 QRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKK ::::::::::::::::.::. ..:: : .:::::::::::::::::::::::::::::: CCDS54 QRKGTTSYNEVADELVSEFTNSNNH-LAADSAYDQKNIRRRVYDALNVLMAMNIISKEKK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KB7 EIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQA :::::::::::::::::::.:.:::.::::::..:::::.::::::::::::::. ::: CCDS54 EIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQN 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB7 SRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMAC . :: ::.:.:::::.:::.:::::::::.:::::::::::::::::::::::::::. CCDS54 QGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSF 170 180 190 200 210 220 310 320 330 340 350 pF1KB7 GLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTV---GGVFITTAGSTSN-----GTRF :::::.:: ::::.:.:::::::: :.:... : :...... :.:: :. . CCDS54 GLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATL 230 240 250 260 270 280 360 370 380 390 400 pF1KB7 SASDLTNG----ADGMLAT-----------SSNGSQYSGSRVETPVSYVGEDDEEDDDFN :....: :. ::: :: .:. : :: ::: :. ::.:.:.. . CCDS54 PQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDS 290 300 310 320 330 340 410 pF1KB7 ENDEDD . : CCDS54 SSPE >>CCDS54647.1 TFDP2 gene_id:7029|Hs108|chr3 (310 aa) initn: 1125 init1: 1028 opt: 1208 Z-score: 1238.6 bits: 237.7 E(32554): 1.1e-62 Smith-Waterman score: 1253; 66.6% identity (82.3% similar) in 311 aa overlap (121-408:1-310) 100 110 120 130 140 150 pF1KB7 QNQPSDSSPWSAGKRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAEFSAAD :::::::::::::::::::::::.::. .. CCDS54 MKVCEKVQRKGTTSYNEVADELVSEFTNSN 10 20 30 160 170 180 190 200 210 pF1KB7 NHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEVERQ :: : .:::::::::::::::::::::::::::::::::::::::::::::::::.:.: CCDS54 NH-LAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQ 40 50 60 70 80 220 230 240 250 260 270 pF1KB7 RRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKT ::.::::::..:::::.::::::::::::::. ::: . :: ::.:.:::::.:::.:: CCDS54 RRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKT 90 100 110 120 130 140 280 290 300 310 320 330 pF1KB7 VIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKAL :::::::.:::::::::::::::::::::::::::. :::::.:: ::::.:.::::::: CCDS54 VIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKAL 150 160 170 180 190 200 340 350 360 370 pF1KB7 EPYVTEMAQGTV---GGVFITTAGSTSN-----GTRFSASDLTNG----ADGMLAT---- : :.:... : :...... :.:: :. . :....: :. ::: CCDS54 EGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFL 210 220 230 240 250 260 380 390 400 410 pF1KB7 -------SSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDEDD :: .:. : :: ::: :. ::.:.:.. . . : CCDS54 APNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE 270 280 290 300 310 410 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:05:30 2016 done: Sat Nov 5 10:05:31 2016 Total Scan time: 2.950 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]