FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7702, 461 aa 1>>>pF1KB7702 461 - 461 aa - 461 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7065+/-0.000424; mu= 2.4381+/- 0.026 mean_var=435.2599+/-89.903, 0's: 0 Z-trim(123.3): 386 B-trim: 1421 in 1/61 Lambda= 0.061475 statistics sampled from 42462 (42857) to 42462 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.502), width: 16 Scan time: 9.750 The best scores are: opt bits E(85289) NP_004950 (OMIM: 184757,612964,612965,613957) ster ( 461) 3209 298.6 2.3e-80 XP_005251928 (OMIM: 184757,612964,612965,613957) P ( 461) 3209 298.6 2.3e-80 XP_011516757 (OMIM: 184757,612964,612965,613957) P ( 461) 3209 298.6 2.3e-80 XP_005245119 (OMIM: 604453) PREDICTED: nuclear rec ( 469) 1900 182.5 2.1e-45 XP_011507684 (OMIM: 604453) PREDICTED: nuclear rec ( 469) 1900 182.5 2.1e-45 NP_001263393 (OMIM: 604453) nuclear receptor subfa ( 469) 1900 182.5 2.1e-45 NP_003813 (OMIM: 604453) nuclear receptor subfamil ( 495) 1900 182.6 2.1e-45 XP_011507686 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 1900 182.6 2.1e-45 XP_011507683 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 1900 182.6 2.1e-45 XP_016856393 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 1900 182.6 2.1e-45 XP_011507682 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 1900 182.6 2.1e-45 NP_995582 (OMIM: 604453) nuclear receptor subfamil ( 541) 1900 182.6 2.2e-45 XP_016877955 (OMIM: 600825) PREDICTED: nuclear rec ( 460) 419 51.2 7.1e-06 XP_011520179 (OMIM: 600825) PREDICTED: nuclear rec ( 467) 419 51.2 7.1e-06 NP_599024 (OMIM: 600825) nuclear receptor ROR-alph ( 468) 419 51.2 7.1e-06 XP_005254641 (OMIM: 600825) PREDICTED: nuclear rec ( 477) 419 51.2 7.2e-06 XP_011520177 (OMIM: 600825) PREDICTED: nuclear rec ( 504) 419 51.2 7.5e-06 NP_599023 (OMIM: 600825) nuclear receptor ROR-alph ( 523) 419 51.3 7.6e-06 XP_011520176 (OMIM: 600825) PREDICTED: nuclear rec ( 525) 419 51.3 7.6e-06 NP_002934 (OMIM: 600825) nuclear receptor ROR-alph ( 548) 419 51.3 7.8e-06 NP_599022 (OMIM: 600825) nuclear receptor ROR-alph ( 556) 419 51.3 7.9e-06 NP_068370 (OMIM: 602408) nuclear receptor subfamil ( 614) 406 50.2 1.9e-05 NP_004443 (OMIM: 602167,608565) steroid hormone re ( 508) 397 49.3 2.9e-05 XP_016876575 (OMIM: 602167,608565) PREDICTED: ster ( 508) 397 49.3 2.9e-05 XP_011534856 (OMIM: 602167,608565) PREDICTED: ster ( 529) 397 49.3 3e-05 XP_011534855 (OMIM: 602167,608565) PREDICTED: ster ( 531) 397 49.3 3e-05 XP_016856133 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 XP_016856136 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 XP_016856129 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 NP_001230441 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 NP_001230442 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 XP_016856130 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 NP_001230438 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 XP_016856131 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 NP_001230448 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 NP_001230440 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 XP_016856128 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 NP_996318 (OMIM: 602969) estrogen-related receptor ( 435) 395 49.0 3e-05 NP_001230444 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 XP_016856135 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 NP_001127757 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 XP_016856134 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 NP_001230443 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 XP_016856127 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 NP_996317 (OMIM: 602969) estrogen-related receptor ( 435) 395 49.0 3e-05 NP_001230439 (OMIM: 602969) estrogen-related recep ( 435) 395 49.0 3e-05 XP_016856138 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 XP_016856137 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 395 49.0 3e-05 XP_016876574 (OMIM: 602167,608565) PREDICTED: ster ( 552) 397 49.3 3e-05 >>NP_004950 (OMIM: 184757,612964,612965,613957) steroido (461 aa) initn: 3209 init1: 3209 opt: 3209 Z-score: 1563.8 bits: 298.6 E(85289): 2.3e-80 Smith-Waterman score: 3209; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL 370 380 390 400 410 420 430 440 450 460 pF1KB7 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT ::::::::::::::::::::::::::::::::::::::::: NP_004 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT 430 440 450 460 >>XP_005251928 (OMIM: 184757,612964,612965,613957) PREDI (461 aa) initn: 3209 init1: 3209 opt: 3209 Z-score: 1563.8 bits: 298.6 E(85289): 2.3e-80 Smith-Waterman score: 3209; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL 370 380 390 400 410 420 430 440 450 460 pF1KB7 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT ::::::::::::::::::::::::::::::::::::::::: XP_005 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT 430 440 450 460 >>XP_011516757 (OMIM: 184757,612964,612965,613957) PREDI (461 aa) initn: 3209 init1: 3209 opt: 3209 Z-score: 1563.8 bits: 298.6 E(85289): 2.3e-80 Smith-Waterman score: 3209; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL 370 380 390 400 410 420 430 440 450 460 pF1KB7 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT ::::::::::::::::::::::::::::::::::::::::: XP_011 LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT 430 440 450 460 >>XP_005245119 (OMIM: 604453) PREDICTED: nuclear recepto (469 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 936.3 bits: 182.5 E(85289): 2.1e-45 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (1-460:2-468) 10 20 30 40 50 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDK ..:::::::.:::::::::::::::::::::::::::::::::::.::: :.:.:.::: XP_005 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 TQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFK :::::::.:::::::.:::.:::::::::::::::::::::::::::::::: :::::.: XP_005 TQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 LETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGL----AAGPPAG-PLGDFGAPALPMAVP ::. . . : ..:. ::: :: ::. . : . . :..: XP_005 LEAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLPLNHAALPPTDYDRSPFVTSPISMTMP 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 GAHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPF-SGGP-NVPELILQLL :: : :: : ::.::::::::.::.: :. . :.: . . ...: ..:.:::.:: XP_005 -PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELL 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 QLEPDEDQVRARILGCLQEP--TKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKEL . :::: ::.:.:.. ::. ..:. .. ..:::.:.:::::..:::.::: . :.:: XP_005 KCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFREL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 EVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVL .: ::: ::::::::::..::::::: :::::::.:::::.:. . .:.:::. :..:. XP_005 KVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 RAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHY .::::: .: .::.:..:::::::..:::::.: :.: ::. .::..::::::::.:.: XP_005 HAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNY 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB7 PHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT :. .:: :::: : :.::.::::.::::.:::....: ::::::::.::. XP_005 PQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA 420 430 440 450 460 >>XP_011507684 (OMIM: 604453) PREDICTED: nuclear recepto (469 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 936.3 bits: 182.5 E(85289): 2.1e-45 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (1-460:2-468) 10 20 30 40 50 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDK ..:::::::.:::::::::::::::::::::::::::::::::::.::: :.:.:.::: XP_011 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 TQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFK :::::::.:::::::.:::.:::::::::::::::::::::::::::::::: :::::.: XP_011 TQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 LETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGL----AAGPPAG-PLGDFGAPALPMAVP ::. . . : ..:. ::: :: ::. . : . . :..: XP_011 LEAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLPLNHAALPPTDYDRSPFVTSPISMTMP 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 GAHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPF-SGGP-NVPELILQLL :: : :: : ::.::::::::.::.: :. . :.: . . ...: ..:.:::.:: XP_011 -PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELL 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 QLEPDEDQVRARILGCLQEP--TKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKEL . :::: ::.:.:.. ::. ..:. .. ..:::.:.:::::..:::.::: . :.:: XP_011 KCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFREL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 EVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVL .: ::: ::::::::::..::::::: :::::::.:::::.:. . .:.:::. :..:. XP_011 KVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 RAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHY .::::: .: .::.:..:::::::..:::::.: :.: ::. .::..::::::::.:.: XP_011 HAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNY 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB7 PHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT :. .:: :::: : :.::.::::.::::.:::....: ::::::::.::. XP_011 PQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA 420 430 440 450 460 >>NP_001263393 (OMIM: 604453) nuclear receptor subfamily (469 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 936.3 bits: 182.5 E(85289): 2.1e-45 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (1-460:2-468) 10 20 30 40 50 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDK ..:::::::.:::::::::::::::::::::::::::::::::::.::: :.:.:.::: NP_001 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 TQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFK :::::::.:::::::.:::.:::::::::::::::::::::::::::::::: :::::.: NP_001 TQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 LETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGL----AAGPPAG-PLGDFGAPALPMAVP ::. . . : ..:. ::: :: ::. . : . . :..: NP_001 LEAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLPLNHAALPPTDYDRSPFVTSPISMTMP 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 GAHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPF-SGGP-NVPELILQLL :: : :: : ::.::::::::.::.: :. . :.: . . ...: ..:.:::.:: NP_001 -PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELL 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 QLEPDEDQVRARILGCLQEP--TKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKEL . :::: ::.:.:.. ::. ..:. .. ..:::.:.:::::..:::.::: . :.:: NP_001 KCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFREL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 EVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVL .: ::: ::::::::::..::::::: :::::::.:::::.:. . .:.:::. :..:. NP_001 KVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 RAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHY .::::: .: .::.:..:::::::..:::::.: :.: ::. .::..::::::::.:.: NP_001 HAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNY 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB7 PHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT :. .:: :::: : :.::.::::.::::.:::....: ::::::::.::. NP_001 PQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA 420 430 440 450 460 >>NP_003813 (OMIM: 604453) nuclear receptor subfamily 5 (495 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 936.0 bits: 182.6 E(85289): 2.1e-45 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (1-460:28-494) 10 20 30 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESC ..:::::::.::::::::::::::::::::::: NP_003 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 KGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRN ::::::::::::.::: :.:.:.::::::::::.:::::::.:::.:::::::::::::: NP_003 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 KFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGL- :::::::::::::::::: :::::.:::. . . : ..:. ::: NP_003 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLP 130 140 150 160 170 160 170 180 190 200 pF1KB7 ---AAGPPAG-PLGDFGAPALPMAVPGAHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQP :: ::. . : . . :..: :: : :: : ::.::::::::.::.: :. NP_003 LNHAALPPTDYDRSPFVTSPISMTMP-PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPES 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB7 GLPYGYPEPF-SGGP-NVPELILQLLQLEPDEDQVRARILGCLQEP--TKSRPDQPAAFG . :.: . . ...: ..:.:::.::. :::: ::.:.:.. ::. ..:. .. ..:: NP_003 IMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFG 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB7 LLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSI :.:.:::::..:::.::: . :.::.: ::: ::::::::::..::::::: ::::::: NP_003 LMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSI 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB7 LLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKF .:::::.:. . .:.:::. :..:. .::::: .: .::.:..:::::::..:::::.: NP_003 FLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN 360 370 380 390 400 410 390 400 410 420 430 440 pF1KB7 LNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLG :.: ::. .::..::::::::.:.::. .:: :::: : :.::.::::.::::.:::. NP_003 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN 420 430 440 450 460 470 450 460 pF1KB7 NEMPRNNLLIEMLQAKQT ...: ::::::::.::. NP_003 GDVPYNNLLIEMLHAKRA 480 490 >>XP_011507686 (OMIM: 604453) PREDICTED: nuclear recepto (501 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 936.0 bits: 182.6 E(85289): 2.1e-45 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (1-460:34-500) 10 20 30 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTC ..:::::::.:::::::::::::::::::: XP_011 KVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 ESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRG :::::::::::::::.::: :.:.:.::::::::::.:::::::.:::.::::::::::: XP_011 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 GRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPK ::::::::::::::::::::: :::::.:::. . . : ..:. : XP_011 GRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQV-IQAMPSDLTISSAIQNIHSAS-K 130 140 150 160 170 180 160 170 180 190 200 pF1KB7 GL----AAGPPAG-PLGDFGAPALPMAVPGAHGPLAGY-LYPAFPGRAIKSEYPEPYASP :: :: ::. . : . . :..: :: : :: : ::.::::::::.::.: XP_011 GLPLNHAALPPTDYDRSPFVTSPISMTMP-PHGSLQGYQTYGHFPSRAIKSEYPDPYTSS 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 PQPGLPYGYPEPF-SGGP-NVPELILQLLQLEPDEDQVRARILGCLQEP--TKSRPDQPA :. . :.: . . ...: ..:.:::.::. :::: ::.:.:.. ::. ..:. .. . XP_011 PESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 AFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKE .:::.:.:::::..:::.::: . :.::.: ::: ::::::::::..::::::: :::: XP_011 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 GSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLD :::.:::::.:. . .:.:::. :..:. .::::: .: .::.:..:::::::..::::: XP_011 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLD 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 LKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHK .: :.: ::. .::..::::::::.:.::. .:: :::: : :.::.::::.::::.: XP_011 VKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYK 430 440 450 460 470 480 450 460 pF1KB7 HLGNEMPRNNLLIEMLQAKQT ::....: ::::::::.::. XP_011 HLNGDVPYNNLLIEMLHAKRA 490 500 >>XP_011507683 (OMIM: 604453) PREDICTED: nuclear recepto (501 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 936.0 bits: 182.6 E(85289): 2.1e-45 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (1-460:34-500) 10 20 30 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTC ..:::::::.:::::::::::::::::::: XP_011 KVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 ESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRG :::::::::::::::.::: :.:.:.::::::::::.:::::::.:::.::::::::::: XP_011 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 GRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPK ::::::::::::::::::::: :::::.:::. . . : ..:. : XP_011 GRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQV-IQAMPSDLTISSAIQNIHSAS-K 130 140 150 160 170 180 160 170 180 190 200 pF1KB7 GL----AAGPPAG-PLGDFGAPALPMAVPGAHGPLAGY-LYPAFPGRAIKSEYPEPYASP :: :: ::. . : . . :..: :: : :: : ::.::::::::.::.: XP_011 GLPLNHAALPPTDYDRSPFVTSPISMTMP-PHGSLQGYQTYGHFPSRAIKSEYPDPYTSS 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 PQPGLPYGYPEPF-SGGP-NVPELILQLLQLEPDEDQVRARILGCLQEP--TKSRPDQPA :. . :.: . . ...: ..:.:::.::. :::: ::.:.:.. ::. ..:. .. . XP_011 PESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 AFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKE .:::.:.:::::..:::.::: . :.::.: ::: ::::::::::..::::::: :::: XP_011 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 GSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLD :::.:::::.:. . .:.:::. :..:. .::::: .: .::.:..:::::::..::::: XP_011 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLD 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 LKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHK .: :.: ::. .::..::::::::.:.::. .:: :::: : :.::.::::.::::.: XP_011 VKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYK 430 440 450 460 470 480 450 460 pF1KB7 HLGNEMPRNNLLIEMLQAKQT ::....: ::::::::.::. XP_011 HLNGDVPYNNLLIEMLHAKRA 490 500 >>XP_016856393 (OMIM: 604453) PREDICTED: nuclear recepto (501 aa) initn: 1857 init1: 879 opt: 1900 Z-score: 936.0 bits: 182.6 E(85289): 2.1e-45 Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (1-460:34-500) 10 20 30 pF1KB7 MDYSYDEDLDELCPVCGDKVSGYHYGLLTC ..:::::::.:::::::::::::::::::: XP_016 KVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 ESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRG :::::::::::::::.::: :.:.:.::::::::::.:::::::.:::.::::::::::: XP_016 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 GRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPK ::::::::::::::::::::: :::::.:::. . . : ..:. : XP_016 GRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQV-IQAMPSDLTISSAIQNIHSAS-K 130 140 150 160 170 180 160 170 180 190 200 pF1KB7 GL----AAGPPAG-PLGDFGAPALPMAVPGAHGPLAGY-LYPAFPGRAIKSEYPEPYASP :: :: ::. . : . . :..: :: : :: : ::.::::::::.::.: XP_016 GLPLNHAALPPTDYDRSPFVTSPISMTMP-PHGSLQGYQTYGHFPSRAIKSEYPDPYTSS 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 PQPGLPYGYPEPF-SGGP-NVPELILQLLQLEPDEDQVRARILGCLQEP--TKSRPDQPA :. . :.: . . ...: ..:.:::.::. :::: ::.:.:.. ::. ..:. .. . XP_016 PESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 AFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKE .:::.:.:::::..:::.::: . :.::.: ::: ::::::::::..::::::: :::: XP_016 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 GSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLD :::.:::::.:. . .:.:::. :..:. .::::: .: .::.:..:::::::..::::: XP_016 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLD 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 LKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHK .: :.: ::. .::..::::::::.:.::. .:: :::: : :.::.::::.::::.: XP_016 VKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYK 430 440 450 460 470 480 450 460 pF1KB7 HLGNEMPRNNLLIEMLQAKQT ::....: ::::::::.::. XP_016 HLNGDVPYNNLLIEMLHAKRA 490 500 461 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:10:31 2016 done: Fri Nov 4 09:10:33 2016 Total Scan time: 9.750 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]