FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7706, 465 aa 1>>>pF1KB7706 465 - 465 aa - 465 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.6391+/-0.000411; mu= -10.6428+/- 0.026 mean_var=349.9765+/-70.447, 0's: 0 Z-trim(122.5): 42 B-trim: 0 in 0/60 Lambda= 0.068557 statistics sampled from 40618 (40660) to 40618 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.477), width: 16 Scan time: 11.210 The best scores are: opt bits E(85289) XP_016864959 (OMIM: 603110) PREDICTED: mothers aga ( 465) 3271 337.1 6e-92 NP_001001420 (OMIM: 603110) mothers against decape ( 465) 3271 337.1 6e-92 NP_001001419 (OMIM: 603110) mothers against decape ( 465) 3271 337.1 6e-92 NP_005894 (OMIM: 603110) mothers against decapenta ( 465) 3271 337.1 6e-92 XP_011530263 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2926 303.0 1.1e-81 XP_011530265 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2926 303.0 1.1e-81 XP_005263049 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2926 303.0 1.1e-81 NP_001003688 (OMIM: 601595) mothers against decape ( 465) 2926 303.0 1.1e-81 XP_011530264 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2926 303.0 1.1e-81 XP_006714280 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2926 303.0 1.1e-81 XP_011530266 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2926 303.0 1.1e-81 NP_005891 (OMIM: 601595) mothers against decapenta ( 465) 2926 303.0 1.1e-81 NP_001120689 (OMIM: 603295,615342) mothers against ( 467) 2584 269.2 1.7e-71 XP_006719890 (OMIM: 603295,615342) PREDICTED: moth ( 479) 2248 236.0 1.8e-61 XP_016881234 (OMIM: 601366) PREDICTED: mothers aga ( 467) 1402 152.3 2.7e-36 XP_005258316 (OMIM: 601366) PREDICTED: mothers aga ( 467) 1402 152.3 2.7e-36 XP_006722514 (OMIM: 601366) PREDICTED: mothers aga ( 467) 1402 152.3 2.7e-36 NP_001003652 (OMIM: 601366) mothers against decape ( 467) 1402 152.3 2.7e-36 NP_005892 (OMIM: 601366) mothers against decapenta ( 467) 1402 152.3 2.7e-36 NP_005896 (OMIM: 603295,615342) mothers against de ( 430) 1346 146.7 1.2e-34 XP_005266458 (OMIM: 603295,615342) PREDICTED: moth ( 442) 1232 135.4 3e-31 XP_011524287 (OMIM: 601366) PREDICTED: mothers aga ( 414) 1224 134.6 4.9e-31 XP_016881237 (OMIM: 601366) PREDICTED: mothers aga ( 414) 1224 134.6 4.9e-31 XP_016881236 (OMIM: 601366) PREDICTED: mothers aga ( 418) 1224 134.6 4.9e-31 XP_011524286 (OMIM: 601366) PREDICTED: mothers aga ( 425) 1224 134.6 5e-31 NP_001129409 (OMIM: 601366) mothers against decape ( 437) 1224 134.7 5.1e-31 XP_016881235 (OMIM: 601366) PREDICTED: mothers aga ( 437) 1224 134.7 5.1e-31 NP_001138574 (OMIM: 603109,613795) mothers against ( 320) 1218 134.0 6e-31 XP_011519862 (OMIM: 603109,613795) PREDICTED: moth ( 376) 1218 134.0 6.8e-31 NP_001138575 (OMIM: 603109,613795) mothers against ( 381) 1218 134.0 6.9e-31 NP_005893 (OMIM: 603109,613795) mothers against de ( 425) 1218 134.0 7.5e-31 XP_011519861 (OMIM: 603109,613795) PREDICTED: moth ( 381) 1192 131.4 4.1e-30 NP_001138576 (OMIM: 603109,613795) mothers against ( 230) 1151 127.2 4.5e-29 XP_016881239 (OMIM: 601366) PREDICTED: mothers aga ( 227) 1148 126.9 5.5e-29 XP_005266460 (OMIM: 603295,615342) PREDICTED: moth ( 393) 1046 117.0 9.3e-26 XP_005266461 (OMIM: 603295,615342) PREDICTED: moth ( 356) 991 111.5 3.7e-24 XP_016881238 (OMIM: 601366) PREDICTED: mothers aga ( 263) 513 64.2 5e-10 NP_005350 (OMIM: 139210,174900,175050,260350,60099 ( 552) 485 61.6 6.2e-09 XP_011519863 (OMIM: 602931,614823) PREDICTED: moth ( 235) 346 47.6 4.3e-05 NP_005576 (OMIM: 602931,614823) mothers against de ( 496) 348 48.0 6.8e-05 NP_001177751 (OMIM: 602932,612229) mothers against ( 211) 292 42.3 0.0016 NP_001177752 (OMIM: 602932,612229) mothers against ( 238) 292 42.3 0.0018 >>XP_016864959 (OMIM: 603110) PREDICTED: mothers against (465 aa) initn: 3271 init1: 3271 opt: 3271 Z-score: 1771.7 bits: 337.1 E(85289): 6e-92 Smith-Waterman score: 3271; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW 370 380 390 400 410 420 430 440 450 460 pF1KB7 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 430 440 450 460 >>NP_001001420 (OMIM: 603110) mothers against decapentap (465 aa) initn: 3271 init1: 3271 opt: 3271 Z-score: 1771.7 bits: 337.1 E(85289): 6e-92 Smith-Waterman score: 3271; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW 370 380 390 400 410 420 430 440 450 460 pF1KB7 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 430 440 450 460 >>NP_001001419 (OMIM: 603110) mothers against decapentap (465 aa) initn: 3271 init1: 3271 opt: 3271 Z-score: 1771.7 bits: 337.1 E(85289): 6e-92 Smith-Waterman score: 3271; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW 370 380 390 400 410 420 430 440 450 460 pF1KB7 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 430 440 450 460 >>NP_005894 (OMIM: 603110) mothers against decapentapleg (465 aa) initn: 3271 init1: 3271 opt: 3271 Z-score: 1771.7 bits: 337.1 E(85289): 6e-92 Smith-Waterman score: 3271; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW 370 380 390 400 410 420 430 440 450 460 pF1KB7 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::::::::: NP_005 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 430 440 450 460 >>XP_011530263 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2687 init1: 1430 opt: 2926 Z-score: 1587.3 bits: 303.0 E(85289): 1.1e-81 Smith-Waterman score: 2926; 89.7% identity (95.1% similar) in 465 aa overlap (3-465:2-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG ...:::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::.:::::::::::::::::::::::::::::::::::::::::::. ::::::::::: XP_011 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP ::::::::::::::::::::::::.:.:::::::.:::::..:::::: ::::::::.:: XP_011 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 NNTPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNS :. ::: :::: :: :: .:::::.::.:: ::::::.:::::::::.::.: : ::.: XP_011 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 QPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG ::::: : : : . :. ::: :::::::::::::::::::::::::::::::::::: XP_011 QPMDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 NCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVK :::.::::::::::::::.::::::::::::::::::::::::.:::::::::::::::: XP_011 NCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVK 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::: ::::::: XP_011 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_011530265 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2687 init1: 1430 opt: 2926 Z-score: 1587.3 bits: 303.0 E(85289): 1.1e-81 Smith-Waterman score: 2926; 89.7% identity (95.1% similar) in 465 aa overlap (3-465:2-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG ...:::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::.:::::::::::::::::::::::::::::::::::::::::::. ::::::::::: XP_011 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP ::::::::::::::::::::::::.:.:::::::.:::::..:::::: ::::::::.:: XP_011 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 NNTPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNS :. ::: :::: :: :: .:::::.::.:: ::::::.:::::::::.::.: : ::.: XP_011 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 QPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG ::::: : : : . :. ::: :::::::::::::::::::::::::::::::::::: XP_011 QPMDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 NCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVK :::.::::::::::::::.::::::::::::::::::::::::.:::::::::::::::: XP_011 NCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVK 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::: ::::::: XP_011 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_005263049 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2687 init1: 1430 opt: 2926 Z-score: 1587.3 bits: 303.0 E(85289): 1.1e-81 Smith-Waterman score: 2926; 89.7% identity (95.1% similar) in 465 aa overlap (3-465:2-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG ...:::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_005 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::.:::::::::::::::::::::::::::::::::::::::::::. ::::::::::: XP_005 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP ::::::::::::::::::::::::.:.:::::::.:::::..:::::: ::::::::.:: XP_005 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 NNTPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNS :. ::: :::: :: :: .:::::.::.:: ::::::.:::::::::.::.: : ::.: XP_005 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 QPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG ::::: : : : . :. ::: :::::::::::::::::::::::::::::::::::: XP_005 QPMDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 NCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVK :::.::::::::::::::.::::::::::::::::::::::::.:::::::::::::::: XP_005 NCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVK 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::: ::::::: XP_005 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>NP_001003688 (OMIM: 601595) mothers against decapentap (465 aa) initn: 2687 init1: 1430 opt: 2926 Z-score: 1587.3 bits: 303.0 E(85289): 1.1e-81 Smith-Waterman score: 2926; 89.7% identity (95.1% similar) in 465 aa overlap (3-465:2-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG ...:::::::::::::::::::::::::::::::::::::::::::::::::::: :: NP_001 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::.:::::::::::::::::::::::::::::::::::::::::::. ::::::::::: NP_001 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP ::::::::::::::::::::::::.:.:::::::.:::::..:::::: ::::::::.:: NP_001 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 NNTPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNS :. ::: :::: :: :: .:::::.::.:: ::::::.:::::::::.::.: : ::.: NP_001 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 QPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG ::::: : : : . :. ::: :::::::::::::::::::::::::::::::::::: NP_001 QPMDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 NCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVK :::.::::::::::::::.::::::::::::::::::::::::.:::::::::::::::: NP_001 NCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVK 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::: ::::::: NP_001 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_011530264 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2687 init1: 1430 opt: 2926 Z-score: 1587.3 bits: 303.0 E(85289): 1.1e-81 Smith-Waterman score: 2926; 89.7% identity (95.1% similar) in 465 aa overlap (3-465:2-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG ...:::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::.:::::::::::::::::::::::::::::::::::::::::::. ::::::::::: XP_011 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP ::::::::::::::::::::::::.:.:::::::.:::::..:::::: ::::::::.:: XP_011 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 NNTPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNS :. ::: :::: :: :: .:::::.::.:: ::::::.:::::::::.::.: : ::.: XP_011 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 QPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG ::::: : : : . :. ::: :::::::::::::::::::::::::::::::::::: XP_011 QPMDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 NCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVK :::.::::::::::::::.::::::::::::::::::::::::.:::::::::::::::: XP_011 NCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVK 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::: ::::::: XP_011 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_006714280 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2687 init1: 1430 opt: 2926 Z-score: 1587.3 bits: 303.0 E(85289): 1.1e-81 Smith-Waterman score: 2926; 89.7% identity (95.1% similar) in 465 aa overlap (3-465:2-465) 10 20 30 40 50 60 pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG ...:::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_006 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE :::.:::::::::::::::::::::::::::::::::::::::::::. ::::::::::: XP_006 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP ::::::::::::::::::::::::.:.:::::::.:::::..:::::: ::::::::.:: XP_006 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 NNTPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNS :. ::: :::: :: :: .:::::.::.:: ::::::.:::::::::.::.: : ::.: XP_006 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 QPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG ::::: : : : . :. ::: :::::::::::::::::::::::::::::::::::: XP_006 QPMDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 NCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVK :::.::::::::::::::.::::::::::::::::::::::::.:::::::::::::::: XP_006 NCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVK 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS ::::::::::::::::::::::::::::::::::::::: ::::::: XP_006 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 465 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:04:52 2016 done: Fri Nov 4 22:04:53 2016 Total Scan time: 11.210 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]