Result of FASTA (omim) for
pF1KB7714
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7714, 473 aa
1>>>pF1KB7714 473 - 473 aa - 473 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6847+/-0.000375; mu= 16.5732+/- 0.023
mean_var=86.6360+/-17.343, 0's: 0 Z-trim(115.1): 411 B-trim: 1241 in 1/53
Lambda= 0.137792
statistics sampled from 24847 (25275) to 24847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.296), width: 16
Scan time: 9.260
The best scores are: opt bits E(85289)
NP_071285 (OMIM: 603065) nuclear receptor subfamil ( 473) 3217 649.6 5.3e-186
NP_003880 (OMIM: 603065) nuclear receptor subfamil ( 434) 2955 597.5 2.4e-170
NP_148934 (OMIM: 603065) nuclear receptor subfamil ( 397) 1506 309.4 1.1e-83
NP_001017536 (OMIM: 166710,277440,601769) vitamin ( 477) 972 203.3 1.2e-51
NP_001017535 (OMIM: 166710,277440,601769) vitamin ( 427) 965 201.9 2.9e-51
XP_011537022 (OMIM: 166710,277440,601769) PREDICTE ( 427) 965 201.9 2.9e-51
NP_000367 (OMIM: 166710,277440,601769) vitamin D3 ( 427) 965 201.9 2.9e-51
XP_006719650 (OMIM: 166710,277440,601769) PREDICTE ( 427) 965 201.9 2.9e-51
NP_001070947 (OMIM: 603881) nuclear receptor subfa ( 319) 603 129.9 1e-29
NP_005113 (OMIM: 603881) nuclear receptor subfamil ( 348) 603 129.9 1.1e-29
NP_001070948 (OMIM: 603881) nuclear receptor subfa ( 352) 595 128.3 3.4e-29
XP_005245751 (OMIM: 603881) PREDICTED: nuclear rec ( 424) 595 128.4 3.9e-29
NP_001070940 (OMIM: 603881) nuclear receptor subfa ( 324) 583 125.9 1.7e-28
XP_005245754 (OMIM: 603881) PREDICTED: nuclear rec ( 353) 583 125.9 1.8e-28
NP_001070945 (OMIM: 603881) nuclear receptor subfa ( 306) 505 110.4 7.4e-24
NP_001070946 (OMIM: 603881) nuclear receptor subfa ( 339) 497 108.8 2.4e-23
NP_001070944 (OMIM: 603881) nuclear receptor subfa ( 311) 485 106.4 1.2e-22
NP_001070937 (OMIM: 603881) nuclear receptor subfa ( 340) 485 106.4 1.3e-22
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols ( 323) 399 89.3 1.7e-17
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols ( 332) 399 89.3 1.7e-17
XP_011518108 (OMIM: 602423) PREDICTED: oxysterols ( 342) 399 89.3 1.8e-17
NP_001123573 (OMIM: 602423) oxysterols receptor LX ( 387) 399 89.4 2e-17
XP_005252770 (OMIM: 602423) PREDICTED: oxysterols ( 387) 399 89.4 2e-17
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 89.4 2e-17
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 89.4 2e-17
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 89.4 2e-17
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 89.4 2e-17
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 399 89.4 2e-17
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 89.4 2e-17
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 89.4 2.2e-17
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 399 89.4 2.2e-17
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 89.4 2.2e-17
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 89.4 2.2e-17
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 89.4 2.2e-17
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 89.4 2.2e-17
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 89.4 2.2e-17
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 399 89.4 2.2e-17
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 399 89.4 2.2e-17
NP_009052 (OMIM: 600380) oxysterols receptor LXR-b ( 461) 390 87.6 7.8e-17
NP_001070941 (OMIM: 603881) nuclear receptor subfa ( 315) 371 83.7 7.9e-16
NP_001070950 (OMIM: 603881) nuclear receptor subfa ( 357) 371 83.8 8.7e-16
XP_005245750 (OMIM: 603881) PREDICTED: nuclear rec ( 429) 371 83.8 1e-15
XP_016862604 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.0 7e-15
XP_016862602 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.0 7e-15
XP_011532355 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.0 7e-15
XP_016862603 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.0 7e-15
XP_005265481 (OMIM: 145650,188570,190160,274300) P ( 461) 357 81.1 7.4e-15
XP_016862601 (OMIM: 145650,188570,190160,274300) P ( 461) 357 81.1 7.4e-15
XP_011532349 (OMIM: 145650,188570,190160,274300) P ( 461) 357 81.1 7.4e-15
NP_000452 (OMIM: 145650,188570,190160,274300) thyr ( 461) 357 81.1 7.4e-15
>>NP_071285 (OMIM: 603065) nuclear receptor subfamily 1 (473 aa)
initn: 3217 init1: 3217 opt: 3217 Z-score: 3460.3 bits: 649.6 E(85289): 5.3e-186
Smith-Waterman score: 3217; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473)
10 20 30 40 50 60
pF1KB7 MTVTRTHHFKEGSLRAPAIPLHSAAAELASNHPRGPEANLEVRPKESWNHADFVHCEDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MTVTRTHHFKEGSLRAPAIPLHSAAAELASNHPRGPEANLEVRPKESWNHADFVHCEDTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 SYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNR
370 380 390 400 410 420
430 440 450 460 470
pF1KB7 PQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
430 440 450 460 470
>>NP_003880 (OMIM: 603065) nuclear receptor subfamily 1 (434 aa)
initn: 2955 init1: 2955 opt: 2955 Z-score: 3179.3 bits: 597.5 E(85289): 2.4e-170
Smith-Waterman score: 2955; 99.8% identity (100.0% similar) in 434 aa overlap (40-473:1-434)
10 20 30 40 50 60
pF1KB7 KEGSLRAPAIPLHSAAAELASNHPRGPEANLEVRPKESWNHADFVHCEDTESVPGKPSVN
.:::::::::::::::::::::::::::::
NP_003 MEVRPKESWNHADFVHCEDTESVPGKPSVN
10 20 30
70 80 90 100 110 120
pF1KB7 ADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 RRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMM
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 IRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 VSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 DQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYML
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 KKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF
340 350 360 370 380 390
430 440 450 460 470
pF1KB7 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
::::::::::::::::::::::::::::::::::::::::::::
NP_003 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
400 410 420 430
>>NP_148934 (OMIM: 603065) nuclear receptor subfamily 1 (397 aa)
initn: 1506 init1: 1506 opt: 1506 Z-score: 1623.1 bits: 309.4 E(85289): 1.1e-83
Smith-Waterman score: 2621; 91.2% identity (91.5% similar) in 434 aa overlap (40-473:1-397)
10 20 30 40 50 60
pF1KB7 KEGSLRAPAIPLHSAAAELASNHPRGPEANLEVRPKESWNHADFVHCEDTESVPGKPSVN
.:::::::::::::::::::::::::::::
NP_148 MEVRPKESWNHADFVHCEDTESVPGKPSVN
10 20 30
70 80 90 100 110 120
pF1KB7 ADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 ADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 RRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 RRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMM
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 IRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLK
:::::::::::::::::::::::
NP_148 IRELMDAQMKTFDTTFSHFKNFR-------------------------------------
160 170
250 260 270 280 290 300
pF1KB7 VSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 VSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIE
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB7 DQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 DQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYML
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB7 KKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 KKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF
300 310 320 330 340 350
430 440 450 460 470
pF1KB7 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
::::::::::::::::::::::::::::::::::::::::::::
NP_148 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
360 370 380 390
>>NP_001017536 (OMIM: 166710,277440,601769) vitamin D3 r (477 aa)
initn: 969 init1: 297 opt: 972 Z-score: 1048.3 bits: 203.3 E(85289): 1.2e-51
Smith-Waterman score: 1057; 40.4% identity (68.7% similar) in 453 aa overlap (32-469:34-473)
10 20 30 40 50 60
pF1KB7 TVTRTHHFKEGSLRAPAIPLHSAAAELASNHPRGPEANLEVRPKESWNHADFVHCEDTES
: :.: .. . : : .: . :
NP_001 RNKKRSDWLSMVLRTAGVEEAFGSEVSVRPHRRAPLGSTYLPPAPSGMEA----MAASTS
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKG
.: :. . :..: :.:: ::::.:::.:::.::::::::::::.:::.: . ::: .:
NP_001 LPD-PG-DFDRNV--PRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPF-NG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 ACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQG
:.::. .::.::::::..:.. :: ::.:..:: :...: .: ..: :.. . : .
NP_001 DCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPK-
120 130 140 150 160 170
190 200 210 220 230
pF1KB7 LTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----ELPESLQAPSREEAAK
:.:::. .: :.::. ::.: :.: : .:: : ...: :.: ..:: ..
NP_001 LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSF--SGD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 WSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGI
:. .: : .. : .. . : : . :. . .:.:::.::. .: .. .
NP_001 SSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQKV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 ISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYC--LED-T
:.:::.: :::: :::: :::..:.:. .:: : :. . .: :: .: . : :
NP_001 IGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVT
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 AGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAI
.: . :.::..::. ::::.:::::.::..:: . ::::::: . ... .:....
NP_001 KAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSN
360 370 380 390 400 410
420 430 440 450 460
pF1KB7 TLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFA----TPLMQE
::..::.: .: :. ..:. :.. :..:::.: .:... : ...: :::. :
NP_001 TLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLSFQPECSMKLTPLVLE
420 430 440 450 460 470
470
pF1KB7 LFGITGS
.::
NP_001 VFGNEIS
>>NP_001017535 (OMIM: 166710,277440,601769) vitamin D3 r (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1041.4 bits: 201.9 E(85289): 2.9e-51
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (77-469:21-423)
50 60 70 80 90 100
pF1KB7 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_001 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_001 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
170 180 190 200 210 220
pF1KB7 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
NP_001 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
230 240 250 260 270
pF1KB7 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
NP_001 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB7 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_001 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB7 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_001 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB7 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
NP_001 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
460 470
pF1KB7 IHPFA----TPLMQELFGITGS
..: :::. :.::
NP_001 FQPECSMKLTPLVLEVFGNEIS
410 420
>>XP_011537022 (OMIM: 166710,277440,601769) PREDICTED: v (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1041.4 bits: 201.9 E(85289): 2.9e-51
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (77-469:21-423)
50 60 70 80 90 100
pF1KB7 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
XP_011 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
XP_011 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
170 180 190 200 210 220
pF1KB7 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
XP_011 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
230 240 250 260 270
pF1KB7 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
XP_011 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB7 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
XP_011 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB7 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
XP_011 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB7 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
XP_011 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
460 470
pF1KB7 IHPFA----TPLMQELFGITGS
..: :::. :.::
XP_011 FQPECSMKLTPLVLEVFGNEIS
410 420
>>NP_000367 (OMIM: 166710,277440,601769) vitamin D3 rece (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1041.4 bits: 201.9 E(85289): 2.9e-51
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (77-469:21-423)
50 60 70 80 90 100
pF1KB7 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_000 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_000 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
170 180 190 200 210 220
pF1KB7 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
NP_000 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
230 240 250 260 270
pF1KB7 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
NP_000 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB7 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_000 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB7 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_000 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB7 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
NP_000 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
460 470
pF1KB7 IHPFA----TPLMQELFGITGS
..: :::. :.::
NP_000 FQPECSMKLTPLVLEVFGNEIS
410 420
>>XP_006719650 (OMIM: 166710,277440,601769) PREDICTED: v (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1041.4 bits: 201.9 E(85289): 2.9e-51
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (77-469:21-423)
50 60 70 80 90 100
pF1KB7 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
XP_006 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
110 120 130 140 150 160
pF1KB7 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
XP_006 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
170 180 190 200 210 220
pF1KB7 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
XP_006 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
230 240 250 260 270
pF1KB7 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
XP_006 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB7 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
XP_006 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB7 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
XP_006 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB7 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
XP_006 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
460 470
pF1KB7 IHPFA----TPLMQELFGITGS
..: :::. :.::
XP_006 FQPECSMKLTPLVLEVFGNEIS
410 420
>>NP_001070947 (OMIM: 603881) nuclear receptor subfamily (319 aa)
initn: 811 init1: 348 opt: 603 Z-score: 654.3 bits: 129.9 E(85289): 1e-29
Smith-Waterman score: 797; 39.3% identity (64.0% similar) in 364 aa overlap (105-467:7-317)
80 90 100 110 120 130
pF1KB7 GGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQ
::..... ::: :.::... ::.:
NP_001 MLPKRSRRTVSKSIGPTCPF-AGSCEVSKTQRRHCP
10 20 30
140 150 160 170 180 190
pF1KB7 ACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELM
::::.:::..::.:.::.: ::. ::: ......: .: :..::. .:: :.
NP_001 ACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLL
40 50 60 70 80
200 210 220 230 240 250
pF1KB7 DAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQL
:. . . : : .: .:: :. : . : ::
NP_001 GAHTRHMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP------------------------
90 100 110 120
260 270 280 290 300 310
pF1KB7 RGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISL
.. :. :.::..:.: .:.:.: . ::.:::::::::
NP_001 --------------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISL
130 140 150 160
320 330 340 350 360 370
pF1KB7 LKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQ
::::: :.:.. .::.: .: .. :: : : .:: : ::: .:: ...:: :.:::
NP_001 LKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQ
170 180 190 200 210 220
380 390 400 410 420 430
pF1KB7 LHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIM
:.: ::::. :..::::::::: :. .:::::..:.::.:::. .. .: :::. :..
NP_001 LQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLL
230 240 250 260 270 280
440 450 460 470
pF1KB7 AMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
..:.:::::: . .. .:: . . ::.::.
NP_001 GLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEICS
290 300 310
>>NP_005113 (OMIM: 603881) nuclear receptor subfamily 1 (348 aa)
initn: 965 init1: 348 opt: 603 Z-score: 653.8 bits: 129.9 E(85289): 1.1e-29
Smith-Waterman score: 972; 42.2% identity (66.1% similar) in 389 aa overlap (80-467:11-346)
50 60 70 80 90 100
pF1KB7 HADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMK
: ::::.:::::::..:::::::::::...
NP_005 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVS
10 20 30 40
110 120 130 140 150 160
pF1KB7 RNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKS
.. ::: :.::... ::.: ::::.:::..::.:.::.: ::. ::: ....
NP_005 KSIGPTCPF-AGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRA
50 60 70 80 90
170 180 190 200 210 220
pF1KB7 ERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQA
..: .: :..::. .:: :. :. . . : : .: .:: :. : . : :
NP_005 QQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-PLPTLA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 PSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYM
: .. :. :.::..:.:
NP_005 P--------------------------------------------VLPLVTHFADINTFM
160
290 300 310 320 330 340
pF1KB7 FKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLED
.:.:.: . ::.:::::::::::::: :.:.. .::.: .: .. :: : : .::
NP_005 VLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIED
170 180 190 200 210 220
350 360 370 380 390 400
pF1KB7 TAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQF
: ::: .:: ...:: :.::::.: ::::. :..::::::::: :. .:::::..
NP_005 GARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEM
230 240 250 260 270 280
410 420 430 440 450 460
pF1KB7 AITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELF
:.::.:::. .. .: :::. :....:.:::::: . .. .:: . . ::.::.
NP_005 ALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEIC
290 300 310 320 330 340
470
pF1KB7 GITGS
NP_005 S
473 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:29:34 2016 done: Sat Nov 5 18:29:35 2016
Total Scan time: 9.260 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]