FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7728, 479 aa 1>>>pF1KB7728 479 - 479 aa - 479 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2103+/-0.000363; mu= 13.6557+/- 0.023 mean_var=85.5543+/-17.202, 0's: 0 Z-trim(115.2): 35 B-trim: 783 in 1/53 Lambda= 0.138661 statistics sampled from 25426 (25461) to 25426 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.299), width: 16 Scan time: 9.720 The best scores are: opt bits E(85289) NP_055368 (OMIM: 609785) transcription factor CP2- ( 479) 3257 661.5 1.4e-189 XP_016859391 (OMIM: 609785) PREDICTED: transcripti ( 406) 2735 557.1 3.3e-158 NP_005644 (OMIM: 189889) alpha-globin transcriptio ( 502) 2414 492.9 8.6e-139 NP_001166923 (OMIM: 189889) alpha-globin transcrip ( 501) 2397 489.5 9e-138 NP_001121632 (OMIM: 609784) upstream-binding prote ( 504) 1854 380.9 4.5e-105 XP_016859393 (OMIM: 609785) PREDICTED: transcripti ( 273) 1746 359.2 8.6e-99 XP_016859394 (OMIM: 609785) PREDICTED: transcripti ( 273) 1738 357.6 2.6e-98 XP_016859392 (OMIM: 609785) PREDICTED: transcripti ( 274) 1524 314.7 2e-85 NP_001121633 (OMIM: 609784) upstream-binding prote ( 540) 1403 290.7 7e-78 NP_055332 (OMIM: 609784) upstream-binding protein ( 540) 1403 290.7 7e-78 NP_001166924 (OMIM: 189889) alpha-globin transcrip ( 450) 848 179.6 1.6e-44 XP_005246216 (OMIM: 609786) PREDICTED: grainyhead- ( 429) 381 86.2 2e-16 XP_016859390 (OMIM: 609786) PREDICTED: grainyhead- ( 467) 366 83.2 1.7e-15 NP_937825 (OMIM: 609786) grainyhead-like protein 1 ( 618) 366 83.3 2.2e-15 XP_006711947 (OMIM: 609786) PREDICTED: grainyhead- ( 441) 361 82.2 3.3e-15 XP_011515609 (OMIM: 608576,608641,616029) PREDICTE ( 591) 355 81.0 9.7e-15 XP_011515608 (OMIM: 608576,608641,616029) PREDICTE ( 609) 355 81.0 9.9e-15 NP_001317522 (OMIM: 608576,608641,616029) grainyhe ( 609) 355 81.0 9.9e-15 NP_079191 (OMIM: 608576,608641,616029) grainyhead- ( 625) 355 81.1 1e-14 XP_011540172 (OMIM: 606713,608317) PREDICTED: grai ( 509) 352 80.4 1.3e-14 XP_011540171 (OMIM: 606713,608317) PREDICTED: grai ( 556) 352 80.4 1.4e-14 NP_001181939 (OMIM: 606713,608317) grainyhead-like ( 556) 352 80.4 1.4e-14 NP_937816 (OMIM: 606713,608317) grainyhead-like pr ( 602) 352 80.4 1.5e-14 NP_067003 (OMIM: 606713,608317) grainyhead-like pr ( 607) 352 80.4 1.5e-14 NP_937817 (OMIM: 606713,608317) grainyhead-like pr ( 626) 352 80.5 1.5e-14 XP_016859389 (OMIM: 609786) PREDICTED: grainyhead- ( 479) 346 79.2 2.8e-14 XP_011508645 (OMIM: 609786) PREDICTED: grainyhead- ( 583) 346 79.2 3.3e-14 XP_006711945 (OMIM: 609786) PREDICTED: grainyhead- ( 630) 346 79.3 3.6e-14 >>NP_055368 (OMIM: 609785) transcription factor CP2-like (479 aa) initn: 3257 init1: 3257 opt: 3257 Z-score: 3524.5 bits: 661.5 E(85289): 1.4e-189 Smith-Waterman score: 3257; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479) 10 20 30 40 50 60 pF1KB7 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 AIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSVYHAIFLEELTTLELIEKIAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSVYHAIFLEELTTLELIEKIAN 370 380 390 400 410 420 430 440 450 460 470 pF1KB7 LYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILKCGL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILKCGL 430 440 450 460 470 >>XP_016859391 (OMIM: 609785) PREDICTED: transcription f (406 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 2961.2 bits: 557.1 E(85289): 3.3e-158 Smith-Waterman score: 2735; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399) 10 20 30 40 50 60 pF1KB7 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 AIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSVYHAIFLEELTTLELIEKIAN ::::::::::::::::::::::::::::::::::::::: XP_016 AIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSDGAELPR 370 380 390 400 430 440 450 460 470 pF1KB7 LYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILKCGL >>NP_005644 (OMIM: 189889) alpha-globin transcription fa (502 aa) initn: 2065 init1: 1475 opt: 2414 Z-score: 2612.8 bits: 492.9 E(85289): 8.6e-139 Smith-Waterman score: 2414; 74.6% identity (91.5% similar) in 469 aa overlap (16-476:35-502) 10 20 30 40 pF1KB7 MLFWHTQPEHYNQHNSGSY-LRDVLALPIFKQEEPQLSPENEARL .:.: . :::::::::::: .: :.:: .. NP_005 LKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPPDNENKI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 PPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVF :.:::::::::::::::.:::::::::::::::.:.:::::.. ..: : ::::.:::: NP_005 LPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 HDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRAS ::::::::::::::::::.::::::::::::.::::.::::.:::::.::::::::::.: NP_005 HDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPTQLNTVEFLWDPAKRTS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 AFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGAD .:::::::::::: :::::::::::::::::::.:::::::::::::::::::::::::: NP_005 VFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGAD 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 RKQKTDREKMEKRTAQEKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGL :::::::::::::: .:::::::::::::::::::::...: ::..:::..:.: .::.: NP_005 RKQKTDREKMEKRTPHEKEKYQPSYETTILTECSPWPEITY-VNNSPSPGFNSSHSSFSL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 GEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRD ::::.::.: : : .:.:::... :.::::::::::: : :::..::::::::..:: NP_005 GEGNGSPNHQPEPPPPVTDNLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRD 310 320 330 340 350 360 350 360 370 380 390 pF1KB7 DLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQEL-----EQNRVPLQQKRDGSGDSNLS :..::::::::::::::.::: :::..::::::: .:.. ::.. .:::: . NP_005 DVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQQQQQQQQQKHEDGDSNGT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 --VYHAIFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESC :::::.:::::..:: ::::.:.:::: .: ..:.::::::::..:.::.::::.:.: NP_005 FFVYHAIYLEELTAVELTEKIAQLFSISPCQISQIYKQGPTGIHVLISDEMIQNFQEEAC 430 440 450 460 470 480 460 470 pF1KB7 FVLSTIKAESNDGYHIILKCGL :.:.:.:::.::.:::::: NP_005 FILDTMKAETNDSYHIILK 490 500 >>NP_001166923 (OMIM: 189889) alpha-globin transcription (501 aa) initn: 2385 init1: 1475 opt: 2397 Z-score: 2594.4 bits: 489.5 E(85289): 9e-138 Smith-Waterman score: 2397; 74.4% identity (91.3% similar) in 469 aa overlap (16-476:35-501) 10 20 30 40 pF1KB7 MLFWHTQPEHYNQHNSGSY-LRDVLALPIFKQEEPQLSPENEARL .:.: . :::::::::::: .: :.:: .. NP_001 LKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPPDNENKI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 PPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVF :.:::::::::::::::.:::::::::::::::.:.:::::.. ..: : ::::.:::: NP_001 LPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 HDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRAS ::::::::::::::::::.::::::::::::.::::.::::.:::::.::::::::::.: NP_001 HDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPTQLNTVEFLWDPAKRTS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 AFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGAD .:::::::::::: :::::::::::::::::::.:::::::::::::::::::::::::: NP_001 VFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGAD 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 RKQKTDREKMEKRTAQEKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGL :::::::::::::: .:::::::::::::::::::::...: ::..:::..:.: .::.: NP_001 RKQKTDREKMEKRTPHEKEKYQPSYETTILTECSPWPEITY-VNNSPSPGFNSSHSSFSL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 GEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRD ::::.::.: : : .:.:::... :.::::::::::: : :::..::::::::..:: NP_001 GEGNGSPNHQPEPPPPVTDNLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRD 310 320 330 340 350 360 350 360 370 380 390 pF1KB7 DLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQEL-----EQNRVPLQQKRDGSGDSNLS :..::::::::::::::.::: :::..::::::: .:.. ::.. .:::: . NP_001 DVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQQQQQQQQQKHEDGDSNGT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 --VYHAIFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESC :::::.:::::..:: ::::.:.:::: .: ..:.::::::::..:.::.::::.:.: NP_001 FFVYHAIYLEELTAVELTEKIAQLFSISPCQISQIYKQGPTGIHVLISDEMIQNFQEEAC 430 440 450 460 470 480 460 470 pF1KB7 FVLSTIKAESNDGYHIILKCGL :.:.:.: :.::.:::::: NP_001 FILDTMK-ETNDSYHIILK 490 500 >>NP_001121632 (OMIM: 609784) upstream-binding protein 1 (504 aa) initn: 2156 init1: 1446 opt: 1854 Z-score: 2007.3 bits: 380.9 E(85289): 4.5e-105 Smith-Waterman score: 2176; 68.1% identity (89.2% similar) in 474 aa overlap (16-476:32-504) 10 20 30 40 pF1KB7 MLFWHTQPEHYNQHNSGSY-LRDVLALPIFKQEEPQLSPENEARL .:.: . :::::::::::. .: ..:.. NP_001 AWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETEH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 PPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVF ::.:::.:::::::::::.:::::::::::::::.:.:::.::. ..: : ::::::::: NP_001 PPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 HDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRAS ::::::::::::::::.:.:::::.::.:::.::::.: :..:.::::::::::::::.: NP_001 HDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 AFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGAD ::::::::::::::::::::::::::.:.::::::::::::.:::::::::::::::::: NP_001 AFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGAD 190 200 210 220 230 240 230 240 250 260 270 pF1KB7 RKQKTDREKMEKRTAQEKEKYQPSYETTILTECSPWPDV--AYQVNSAPSPSYN-GSP-- :::::::::::::::.:::::::::.::::::::::::. :: ::..:::. . :: NP_001 RKQKTDREKMEKRTAHEKEKYQPSYDTTILTECSPWPDAPTAY-VNNSPSPAPTFTSPQQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 NSFGLGEGNAS-PTHPVE-ALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGAD .. .. ..:.: :.: . : ...... :::.::..:::: .::::.. :::..::::: NP_001 STCSVPDSNSSSPNHQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGAD 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 LLKMSRDDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNRV-PLQQKRDGSGDS :::....::::::: ::::::.:..:.:.:::..:::::.: .. : ::. .:.. NP_001 LLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQAASSASE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 NLS----VYHAIFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNF : : :::::.:::. . :. .:.: ...: ..:..::::::::::..::..::::: NP_001 NGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNF 430 440 450 460 470 480 460 470 pF1KB7 QDESCFVLSTIKAESNDGYHIILKCGL ::::::..::.::::.:: ::::: NP_001 QDESCFLFSTVKAESSDGIHIILK 490 500 >>XP_016859393 (OMIM: 609785) PREDICTED: transcription f (273 aa) initn: 1744 init1: 1744 opt: 1746 Z-score: 1894.7 bits: 359.2 E(85289): 8.6e-99 Smith-Waterman score: 1746; 96.3% identity (96.7% similar) in 270 aa overlap (1-262:1-270) 10 20 30 40 50 60 pF1KB7 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 EKEKYQPSYETTILTE----CS----PWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPT :::::::::::::::: :: :: . XP_016 EKEKYQPSYETTILTEPQPLCSSADCPWEERSW 250 260 270 >>XP_016859394 (OMIM: 609785) PREDICTED: transcription f (273 aa) initn: 1738 init1: 1738 opt: 1738 Z-score: 1886.0 bits: 357.6 E(85289): 2.6e-98 Smith-Waterman score: 1738; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256) 10 20 30 40 50 60 pF1KB7 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPV :::::::::::::::: XP_016 EKEKYQPSYETTILTEEAQRDPLGTSLAPGVTY 250 260 270 >>XP_016859392 (OMIM: 609785) PREDICTED: transcription f (274 aa) initn: 1524 init1: 1524 opt: 1524 Z-score: 1654.6 bits: 314.7 E(85289): 2e-85 Smith-Waterman score: 1524; 98.7% identity (100.0% similar) in 226 aa overlap (254-479:49-274) 230 240 250 260 270 280 pF1KB7 DRKQKTDREKMEKRTAQEKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFG ...::::::::::::::::::::::::::: XP_016 LLNISAGFLHVALVTCLAVAHCGHWVNAGCVSQCSPWPDVAYQVNSAPSPSYNGSPNSFG 20 30 40 50 60 70 290 300 310 320 330 340 pF1KB7 LGEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSR 80 90 100 110 120 130 350 360 370 380 390 400 pF1KB7 DDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSVYHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSVYHA 140 150 160 170 180 190 410 420 430 440 450 460 pF1KB7 IFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTI 200 210 220 230 240 250 470 pF1KB7 KAESNDGYHIILKCGL :::::::::::::::: XP_016 KAESNDGYHIILKCGL 260 270 >>NP_001121633 (OMIM: 609784) upstream-binding protein 1 (540 aa) initn: 2142 init1: 1385 opt: 1403 Z-score: 1519.2 bits: 290.7 E(85289): 7e-78 Smith-Waterman score: 2031; 62.9% identity (82.7% similar) in 498 aa overlap (16-464:32-528) 10 20 30 40 pF1KB7 MLFWHTQPEHYNQHNSGSY-LRDVLALPIFKQEEPQLSPENEARL .:.: . :::::::::::. .: ..:.. NP_001 AWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETEH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 PPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVF ::.:::.:::::::::::.:::::::::::::::.:.:::.::. ..: : ::::::::: NP_001 PPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 HDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRAS ::::::::::::::::.:.:::::.::.:::.::::.: :..:.::::::::::::::.: NP_001 HDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 AFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGAD ::::::::::::::::::::::::::.:.::::::::::::.:::::::::::::::::: NP_001 AFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGAD 190 200 210 220 230 240 230 240 250 pF1KB7 RKQKTDREKMEKRTAQEKEKYQPSYETTILTE---------------------------- :::::::::::::::.:::::::::.:::::: NP_001 RKQKTDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYG 250 260 270 280 290 300 260 270 280 290 300 pF1KB7 --------CSPWPDV--AYQVNSAPSPSYN-GSP--NSFGLGEGNAS-PTHPVE-ALPVG ::::::. :: ::..:::. . :: .. .. ..:.: :.: . : .. NP_001 DSLAKRGSCSPWPDAPTAY-VNNSPSPAPTFTSPQQSTCSVPDSNSSSPNHQGDGASQTS 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB7 SDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFNA .... :::.::..:::: .::::.. :::..::::::::....::::::: ::::::.:. NP_001 GEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNS 370 380 390 400 410 420 370 380 390 400 410 pF1KB7 IKGRNVRPKMTIYVCQELEQNRV-PLQQKRDGSGDSNLS----VYHAIFLEELTTLELIE .:.:.:::..:::::.: .. : ::. .:.. : : :::::.:::. . :. . NP_001 LKSRSVRPRLTIYVCREQPSSTVLQGQQQAASSASENGSGAPYVYHAIYLEEMIASEVAR 430 440 450 460 470 480 420 430 440 450 460 470 pF1KB7 KIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILK :.: ...: ..:..::::::::::..::..:::::::::::..::.: NP_001 KLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK 490 500 510 520 530 540 pF1KB7 CGL >>NP_055332 (OMIM: 609784) upstream-binding protein 1 is (540 aa) initn: 2142 init1: 1385 opt: 1403 Z-score: 1519.2 bits: 290.7 E(85289): 7e-78 Smith-Waterman score: 2031; 62.9% identity (82.7% similar) in 498 aa overlap (16-464:32-528) 10 20 30 40 pF1KB7 MLFWHTQPEHYNQHNSGSY-LRDVLALPIFKQEEPQLSPENEARL .:.: . :::::::::::. .: ..:.. NP_055 AWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETEH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 PPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVF ::.:::.:::::::::::.:::::::::::::::.:.:::.::. ..: : ::::::::: NP_055 PPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 HDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRAS ::::::::::::::::.:.:::::.::.:::.::::.: :..:.::::::::::::::.: NP_055 HDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 AFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGAD ::::::::::::::::::::::::::.:.::::::::::::.:::::::::::::::::: NP_055 AFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGAD 190 200 210 220 230 240 230 240 250 pF1KB7 RKQKTDREKMEKRTAQEKEKYQPSYETTILTE---------------------------- :::::::::::::::.:::::::::.:::::: NP_055 RKQKTDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYG 250 260 270 280 290 300 260 270 280 290 300 pF1KB7 --------CSPWPDV--AYQVNSAPSPSYN-GSP--NSFGLGEGNAS-PTHPVE-ALPVG ::::::. :: ::..:::. . :: .. .. ..:.: :.: . : .. NP_055 DSLAKRGSCSPWPDAPTAY-VNNSPSPAPTFTSPQQSTCSVPDSNSSSPNHQGDGASQTS 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB7 SDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFNA .... :::.::..:::: .::::.. :::..::::::::....::::::: ::::::.:. NP_055 GEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNS 370 380 390 400 410 420 370 380 390 400 410 pF1KB7 IKGRNVRPKMTIYVCQELEQNRV-PLQQKRDGSGDSNLS----VYHAIFLEELTTLELIE .:.:.:::..:::::.: .. : ::. .:.. : : :::::.:::. . :. . NP_055 LKSRSVRPRLTIYVCREQPSSTVLQGQQQAASSASENGSGAPYVYHAIYLEEMIASEVAR 430 440 450 460 470 480 420 430 440 450 460 470 pF1KB7 KIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILK :.: ...: ..:..::::::::::..::..:::::::::::..::.: NP_055 KLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK 490 500 510 520 530 540 pF1KB7 CGL 479 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 04:46:23 2016 done: Mon Nov 7 04:46:24 2016 Total Scan time: 9.720 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]