FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7731, 432 aa 1>>>pF1KB7731 432 - 432 aa - 432 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.2569+/-0.000416; mu= -5.0691+/- 0.026 mean_var=488.9886+/-100.345, 0's: 0 Z-trim(125.4): 147 B-trim: 969 in 1/61 Lambda= 0.058000 statistics sampled from 48926 (49093) to 48926 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.827), E-opt: 0.2 (0.576), width: 16 Scan time: 11.750 The best scores are: opt bits E(85289) XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 3042 268.4 2.6e-71 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 3042 268.4 2.6e-71 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 3042 268.4 2.6e-71 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 3042 268.4 2.6e-71 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 3042 268.4 2.6e-71 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 3042 268.4 2.6e-71 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 3042 268.4 2.6e-71 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 3042 268.4 2.6e-71 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 1031 100.1 1.2e-20 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 1031 100.1 1.2e-20 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 1031 100.1 1.2e-20 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 1031 100.1 1.2e-20 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 1031 100.1 1.2e-20 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 1031 100.1 1.2e-20 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 1029 99.9 1.3e-20 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 995 96.9 7.3e-20 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 995 97.0 8.3e-20 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 995 97.0 8.3e-20 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 995 97.2 1e-19 XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 995 97.3 1.1e-19 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 883 87.7 6.3e-17 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 883 87.7 6.3e-17 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 883 87.7 6.3e-17 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 883 87.7 6.3e-17 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 883 87.7 6.3e-17 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 883 87.7 6.3e-17 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 883 87.7 6.3e-17 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 404 47.4 5e-05 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 401 47.3 7.8e-05 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 395 46.7 0.0001 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 393 46.5 0.0001 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 386 46.0 0.00018 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 371 44.6 0.00035 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 360 43.8 0.00076 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 357 43.5 0.00084 NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328) 353 43.2 0.0012 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 351 43.0 0.0012 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 349 42.9 0.0014 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 345 42.4 0.0015 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 338 41.8 0.0022 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 338 41.8 0.0022 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 338 41.8 0.0022 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 334 41.6 0.0034 >>XP_011509367 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: XP_011 GRLPEAPKLTHL 430 >>XP_005246566 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: XP_005 GRLPEAPKLTHL 430 >>XP_005246570 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: XP_005 GRLPEAPKLTHL 430 >>XP_011509368 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: XP_011 GRLPEAPKLTHL 430 >>XP_005246567 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: XP_005 GRLPEAPKLTHL 430 >>XP_005246568 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: XP_005 GRLPEAPKLTHL 430 >>NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [Homo (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: NP_008 GRLPEAPKLTHL 430 >>XP_006712540 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1401.4 bits: 268.4 E(85289): 2.6e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 370 380 390 400 410 420 430 pF1KB7 GRLPEAPKLTHL :::::::::::: XP_006 GRLPEAPKLTHL 430 >>NP_002137 (OMIM: 142966) homeobox protein Hox-B3 isofo (431 aa) initn: 1322 init1: 465 opt: 1031 Z-score: 492.0 bits: 100.1 E(85289): 1.2e-20 Smith-Waterman score: 1367; 50.7% identity (68.7% similar) in 454 aa overlap (17-432:1-431) 10 20 30 40 50 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPG--LFGGYGYSKTTDTYGYSTPHQPYPPPAAASS ::::.::.: . :::::. .. .:...: : :: ::. NP_002 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVP--PQPPFQAATH 10 20 30 40 60 70 80 90 100 110 pF1KB7 LDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQ :. :: ::::.:: . :: :. :::::::::: . : :.. :: NP_002 LEGDYQRSACSLQSLGNA-APHAKSKELNGSCMRPGLA----------PEPLSA---PPG 50 60 70 80 120 130 140 150 160 170 pF1KB7 PPPPP--PTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNS ::: :: :. .: :: . :: ::...: :..::::::::::::.:: ::. NP_002 SPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNS---TLTKQIFPWMKESRQTSKLKNN 90 100 110 120 130 140 180 190 200 210 pF1KB7 CATAGESCE------------------------DKSPPGPA-SKRVRTAYTSAQLVELEK ..:.: :::::: : :::.:::::::::::::: NP_002 SPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEK 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB7 EFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSP ::::::::::::::::::::::.:::::::::::::::::::::::. : .. :: :: NP_002 EFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSP 210 220 230 240 250 260 280 290 300 310 320 pF1KB7 P--LGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAA-YTAPLSSCLPQQKR : . ..:: . .. : .:..::::::.:.. : :.: . : ::..: :: NP_002 PQPMQSTAGFMNALHSMTP----SYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKY 270 280 290 300 310 320 330 340 350 360 370 380 pF1KB7 --YAAPEFEPHPMASNGGGFASANLQGSPVYVGGN-FVESMAPASGP-VFNLGHLSHPSS :::.::: . .:::.... ..:::::::::. ... . : .:: ...:.:::: : NP_002 PPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPS 330 340 350 360 370 380 390 400 410 420 430 pF1KB7 ASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSS--QGRLPEAPKLTHL ...::. : . ..:::::.:::::::::.::. :::. :::::::: NP_002 GNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL 390 400 410 420 430 >>XP_011523021 (OMIM: 142966) PREDICTED: homeobox protei (431 aa) initn: 1322 init1: 465 opt: 1031 Z-score: 492.0 bits: 100.1 E(85289): 1.2e-20 Smith-Waterman score: 1367; 50.7% identity (68.7% similar) in 454 aa overlap (17-432:1-431) 10 20 30 40 50 pF1KB7 MLFEQGQQALELPECTMQKAAYYENPG--LFGGYGYSKTTDTYGYSTPHQPYPPPAAASS ::::.::.: . :::::. .. .:...: : :: ::. XP_011 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVP--PQPPFQAATH 10 20 30 40 60 70 80 90 100 110 pF1KB7 LDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQ :. :: ::::.:: . :: :. :::::::::: . : :.. :: XP_011 LEGDYQRSACSLQSLGNA-APHAKSKELNGSCMRPGLA----------PEPLSA---PPG 50 60 70 80 120 130 140 150 160 170 pF1KB7 PPPPP--PTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNS ::: :: :. .: :: . :: ::...: :..::::::::::::.:: ::. XP_011 SPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNS---TLTKQIFPWMKESRQTSKLKNN 90 100 110 120 130 140 180 190 200 210 pF1KB7 CATAGESCE------------------------DKSPPGPA-SKRVRTAYTSAQLVELEK ..:.: :::::: : :::.:::::::::::::: XP_011 SPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEK 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB7 EFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSP ::::::::::::::::::::::.:::::::::::::::::::::::. : .. :: :: XP_011 EFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSP 210 220 230 240 250 260 280 290 300 310 320 pF1KB7 P--LGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAA-YTAPLSSCLPQQKR : . ..:: . .. : .:..::::::.:.. : :.: . : ::..: :: XP_011 PQPMQSTAGFMNALHSMTP----SYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKY 270 280 290 300 310 320 330 340 350 360 370 380 pF1KB7 --YAAPEFEPHPMASNGGGFASANLQGSPVYVGGN-FVESMAPASGP-VFNLGHLSHPSS :::.::: . .:::.... ..:::::::::. ... . : .:: ...:.:::: : XP_011 PPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPS 330 340 350 360 370 380 390 400 410 420 430 pF1KB7 ASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSS--QGRLPEAPKLTHL ...::. : . ..:::::.:::::::::.::. :::. :::::::: XP_011 GNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL 390 400 410 420 430 432 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:17:48 2016 done: Fri Nov 4 09:17:49 2016 Total Scan time: 11.750 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]