FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7737, 436 aa 1>>>pF1KB7737 436 - 436 aa - 436 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7864+/-0.000352; mu= 3.7617+/- 0.022 mean_var=240.3152+/-49.959, 0's: 0 Z-trim(122.9): 76 B-trim: 772 in 1/58 Lambda= 0.082734 statistics sampled from 41806 (41888) to 41806 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.491), width: 16 Scan time: 10.550 The best scores are: opt bits E(85289) XP_016879103 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 3084 380.7 4.1e-105 XP_011544228 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 3084 380.7 4.1e-105 XP_005255580 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 3084 380.7 4.1e-105 NP_004599 (OMIM: 122600,602427) T-box transcriptio ( 436) 3084 380.7 4.1e-105 NP_005985 (OMIM: 600747) T-box transcription facto ( 712) 867 116.3 2.7e-25 XP_011523797 (OMIM: 147891,601719) PREDICTED: T-bo ( 417) 820 110.4 8.9e-24 XP_016877522 (OMIM: 616061) PREDICTED: MAX gene-as (1439) 829 112.0 1e-23 XP_011519703 (OMIM: 616061) PREDICTED: MAX gene-as (1549) 829 112.0 1.1e-23 XP_011523793 (OMIM: 147891,601719) PREDICTED: T-bo ( 608) 820 110.6 1.2e-23 XP_011523792 (OMIM: 147891,601719) PREDICTED: T-bo ( 609) 820 110.6 1.2e-23 NP_060958 (OMIM: 147891,601719) T-box transcriptio ( 545) 819 110.4 1.2e-23 NP_001308049 (OMIM: 147891,601719) T-box transcrip ( 546) 819 110.4 1.2e-23 XP_016877519 (OMIM: 616061) PREDICTED: MAX gene-as (2207) 829 112.2 1.4e-23 NP_001074010 (OMIM: 616061) MAX gene-associated pr (2856) 829 112.3 1.7e-23 XP_005254310 (OMIM: 616061) PREDICTED: MAX gene-as (2906) 829 112.3 1.7e-23 XP_005254309 (OMIM: 616061) PREDICTED: MAX gene-as (2956) 829 112.3 1.7e-23 XP_011519700 (OMIM: 616061) PREDICTED: MAX gene-as (3004) 829 112.3 1.8e-23 XP_011519699 (OMIM: 616061) PREDICTED: MAX gene-as (3005) 829 112.3 1.8e-23 NP_001157745 (OMIM: 616061) MAX gene-associated pr (3065) 829 112.3 1.8e-23 XP_005254306 (OMIM: 616061) PREDICTED: MAX gene-as (3066) 829 112.3 1.8e-23 XP_005254305 (OMIM: 616061) PREDICTED: MAX gene-as (3114) 829 112.3 1.8e-23 XP_005254300 (OMIM: 616061) PREDICTED: MAX gene-as (3115) 829 112.3 1.8e-23 XP_006720506 (OMIM: 616061) PREDICTED: MAX gene-as (3115) 829 112.3 1.8e-23 XP_005254304 (OMIM: 616061) PREDICTED: MAX gene-as (3115) 829 112.3 1.8e-23 XP_005254301 (OMIM: 616061) PREDICTED: MAX gene-as (3115) 829 112.3 1.8e-23 XP_005254303 (OMIM: 616061) PREDICTED: MAX gene-as (3115) 829 112.3 1.8e-23 XP_005254302 (OMIM: 616061) PREDICTED: MAX gene-as (3115) 829 112.3 1.8e-23 XP_016884415 (OMIM: 187500,188400,192430,217095,60 ( 495) 810 109.3 2.3e-23 XP_006724375 (OMIM: 187500,188400,192430,217095,60 ( 495) 810 109.3 2.3e-23 NP_542378 (OMIM: 187500,188400,192430,217095,60205 ( 495) 810 109.3 2.3e-23 XP_016884414 (OMIM: 187500,188400,192430,217095,60 ( 545) 810 109.3 2.5e-23 NP_001071121 (OMIM: 606061,611363) T-box transcrip ( 447) 808 109.0 2.5e-23 NP_005987 (OMIM: 181450,601621) T-box transcriptio ( 723) 811 109.6 2.8e-23 NP_000183 (OMIM: 142900,601620) T-box transcriptio ( 518) 808 109.1 2.8e-23 NP_852259 (OMIM: 142900,601620) T-box transcriptio ( 518) 808 109.1 2.8e-23 XP_016875401 (OMIM: 142900,601620) PREDICTED: T-bo ( 534) 808 109.1 2.9e-23 NP_001317606 (OMIM: 260660,604127) T-box transcrip ( 602) 803 108.5 4.7e-23 NP_001073977 (OMIM: 143100,143400,604613) T-box tr ( 607) 800 108.2 6.1e-23 NP_542448 (OMIM: 142900,601620) T-box transcriptio ( 468) 789 106.8 1.3e-22 NP_689593 (OMIM: 260660,604127) T-box transcriptio ( 496) 781 105.8 2.5e-22 XP_006715665 (OMIM: 143100,143400,604613) PREDICTE ( 364) 774 104.9 3.6e-22 XP_011534551 (OMIM: 143100,143400,604613) PREDICTE ( 372) 774 104.9 3.7e-22 XP_016866962 (OMIM: 143100,143400,604613) PREDICTE ( 376) 774 104.9 3.7e-22 XP_011534550 (OMIM: 143100,143400,604613) PREDICTE ( 377) 774 104.9 3.7e-22 XP_011534549 (OMIM: 143100,143400,604613) PREDICTE ( 379) 774 104.9 3.7e-22 XP_005271218 (OMIM: 260660,604127) PREDICTED: T-bo ( 635) 771 104.7 6.9e-22 NP_001159692 (OMIM: 606061,611363) T-box transcrip ( 297) 755 102.5 1.5e-21 NP_542377 (OMIM: 187500,188400,192430,217095,60205 ( 398) 747 101.7 3.6e-21 XP_016884417 (OMIM: 187500,188400,192430,217095,60 ( 448) 747 101.7 3.9e-21 XP_011543294 (OMIM: 604648) PREDICTED: T-box trans ( 430) 746 101.6 4.1e-21 >>XP_016879103 (OMIM: 122600,602427) PREDICTED: T-box tr (436 aa) initn: 3084 init1: 3084 opt: 3084 Z-score: 2008.1 bits: 380.7 E(85289): 4.1e-105 Smith-Waterman score: 3084; 100.0% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP 370 380 390 400 410 420 430 pF1KB7 YTAPGGYLDVGSKPMY :::::::::::::::: XP_016 YTAPGGYLDVGSKPMY 430 >>XP_011544228 (OMIM: 122600,602427) PREDICTED: T-box tr (436 aa) initn: 3084 init1: 3084 opt: 3084 Z-score: 2008.1 bits: 380.7 E(85289): 4.1e-105 Smith-Waterman score: 3084; 100.0% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP 370 380 390 400 410 420 430 pF1KB7 YTAPGGYLDVGSKPMY :::::::::::::::: XP_011 YTAPGGYLDVGSKPMY 430 >>XP_005255580 (OMIM: 122600,602427) PREDICTED: T-box tr (436 aa) initn: 3084 init1: 3084 opt: 3084 Z-score: 2008.1 bits: 380.7 E(85289): 4.1e-105 Smith-Waterman score: 3084; 100.0% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP 370 380 390 400 410 420 430 pF1KB7 YTAPGGYLDVGSKPMY :::::::::::::::: XP_005 YTAPGGYLDVGSKPMY 430 >>NP_004599 (OMIM: 122600,602427) T-box transcription fa (436 aa) initn: 3084 init1: 3084 opt: 3084 Z-score: 2008.1 bits: 380.7 E(85289): 4.1e-105 Smith-Waterman score: 3084; 100.0% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLP 370 380 390 400 410 420 430 pF1KB7 YTAPGGYLDVGSKPMY :::::::::::::::: NP_004 YTAPGGYLDVGSKPMY 430 >>NP_005985 (OMIM: 600747) T-box transcription factor TB (712 aa) initn: 875 init1: 788 opt: 867 Z-score: 575.2 bits: 116.3 E(85289): 2.7e-25 Smith-Waterman score: 867; 39.5% identity (60.8% similar) in 413 aa overlap (2-397:13-415) 10 20 30 40 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPE--LDTPKLD ::: .. : . .. .:. :: :::: : : : : NP_005 MREPALAASAMAYHP--FHAPRPADFPMSAFLAAAQPSFFPALA----LPPGALAKPLPD 10 20 30 40 50 50 60 70 80 90 100 pF1KB7 CFLSGMEAAPRTLAAHPPLPLLPPAMGTEPAPSAPEALHSL-P------GVSLSLENREL :.: :: . :: : :.: .: . ..:.:: : ...:: .:: NP_005 PGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKEL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 WKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEP : .: ..::::.:::.:::::: .: :.::: .:.:..:.:.. .: ::.... :: NP_005 WDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 SGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRI .:::.:..: :.:::::::::: .:: .::.::..::::. : :: ::.::::::::. NP_005 AGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 HLVRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKR :.::: .. . .. . .. :::: ::.:::::: .:::::: ::::::::..: . .. NP_005 HIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRRE 240 250 260 270 280 290 290 300 310 320 330 pF1KB7 ERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRE--SDPEQAPAPGEATAAPA .: . .:: : .... .. :: :: ..: ::.: . : : NP_005 KRKQLTLPSLRLYEEHCKPERDGAESDASSCDPP---PAREPPTSPGAAPSPLRLHRARA 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB7 PL--CGGPSAEAYLLHPAAFHGAP---SHLP-TRSPSFPEAPDSGRSAPYSAAFLELPHG :.. : ::: : : . ::. :. .: : . : NP_005 EEKSCAADSDPEPERLSEERAGAPLGRSPAPDSASPTRLTEPERARER-RSPERGKEPAE 360 370 380 390 400 410 400 410 420 430 pF1KB7 SGGSGYPAAPPAVPFAPHFLQGGPFPLPYTAPGGYLDVGSKPMY :::.: NP_005 SGGDGPFGLRSLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAF 420 430 440 450 460 470 >>XP_011523797 (OMIM: 147891,601719) PREDICTED: T-box tr (417 aa) initn: 797 init1: 639 opt: 820 Z-score: 547.9 bits: 110.4 E(85289): 8.9e-24 Smith-Waterman score: 820; 46.5% identity (72.0% similar) in 282 aa overlap (18-289:55-328) 10 20 30 40 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPP-ALAEGYRYPELDTPKL ::.. : . .:.:. . . : : XP_011 ARSWESKSKPGMRRPLNKMGERPEPGDAPGGPGESGKKEMLQDKGLSESEEAFRAPGPAL 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 DCFLSGMEAAPRTLAAHPPLPLLPPAMGTEPAP-----SAPEALHSLPGVSLSLENRELW .. ::. : : : :.:. :.: .: : ... .....:...::: XP_011 GE--ASAANAPEPALAAPGLS--GAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELW 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 KEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPS :.: .:::::::::::::::. .:.:::..:...:..:.:..:.: ::.. .: . XP_011 KKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVA 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB7 GKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIH ::::: .: :.:.:::::::::::::: :::...::::. ::: ::.::.::::::::.: XP_011 GKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLH 210 220 230 240 250 260 230 240 250 260 270 pF1KB7 LVRAAQLCSQHWGG----MASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRN .:.: . .. .:. . . ::::.:::::.::: .:::::: :::::::: : . XP_011 IVKADE--NNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFR--GSD 270 280 290 300 310 280 290 300 310 320 330 pF1KB7 CKRERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAP . : ::.. : XP_011 DSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQL 320 330 340 350 360 370 >>XP_016877522 (OMIM: 616061) PREDICTED: MAX gene-associ (1439 aa) initn: 767 init1: 579 opt: 829 Z-score: 546.7 bits: 112.0 E(85289): 1e-23 Smith-Waterman score: 831; 48.8% identity (74.4% similar) in 250 aa overlap (87-332:71-306) 60 70 80 90 100 110 pF1KB7 PRTLAAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKA .. :....:.: .:.:: .::::.:: XP_016 LVTNQDACALASSVSSPVKSKGKICLPADCTVGGITVTLDNNSMWNEFYHRSTEMILTKQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 GRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHP :::::: :: .:::: . .:....:. :::. ::.:.:: :::::::::.. ::.::: XP_016 GRRMFPYCRYWITGLDSNLKYILVMDISPVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 DSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLV---RAAQLCSQHW .::.:: .::.:::::...::::.::: .::.::::::.: ::.::: .:... . . XP_016 ESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKAVEVIQLNG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 GGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGP :. .: ::.: :..:::::: ::::::: ::::::::..: : : .::.. : XP_016 PGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLNNKPQRDGKQK------ 230 240 250 260 270 300 310 320 330 340 350 pF1KB7 EPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPA-PGEATAAPAPLCGGPSAEAYLLH .:.: :. .:. : .: .. . . ::. XP_016 --------NSSDQEGNNISSSSGHRVRLTEGQGSEIQPGDLDPLSRGHETSGKGLEKTSL 280 290 300 310 320 360 370 380 390 400 410 pF1KB7 PAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFL XP_016 NIKRDFLGFMDTDSALSEVPQLKQEISECLIASSFEDDSRVASPLDQNGSFNVVIKEEPL 330 340 350 360 370 380 >>XP_011519703 (OMIM: 616061) PREDICTED: MAX gene-associ (1549 aa) initn: 767 init1: 579 opt: 829 Z-score: 546.3 bits: 112.0 E(85289): 1.1e-23 Smith-Waterman score: 831; 48.8% identity (74.4% similar) in 250 aa overlap (87-332:71-306) 60 70 80 90 100 110 pF1KB7 PRTLAAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKA .. :....:.: .:.:: .::::.:: XP_011 LVTNQDACALASSVSSPVKSKGKICLPADCTVGGITVTLDNNSMWNEFYHRSTEMILTKQ 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 GRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHP :::::: :: .:::: . .:....:. :::. ::.:.:: :::::::::.. ::.::: XP_011 GRRMFPYCRYWITGLDSNLKYILVMDISPVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 DSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLV---RAAQLCSQHW .::.:: .::.:::::...::::.::: .::.::::::.: ::.::: .:... . . XP_011 ESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKAVEVIQLNG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 GGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGP :. .: ::.: :..:::::: ::::::: ::::::::..: : : .::.. : XP_011 PGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLNNKPQRDGKQK------ 230 240 250 260 270 300 310 320 330 340 350 pF1KB7 EPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPA-PGEATAAPAPLCGGPSAEAYLLH .:.: :. .:. : .: .. . . ::. XP_011 --------NSSDQEGNNISSSSGHRVRLTEGQGSEIQPGDLDPLSRGHETSGKGLEKTSL 280 290 300 310 320 360 370 380 390 400 410 pF1KB7 PAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFL XP_011 NIKRDFLGFMDTDSALSEVPQLKQEISECLIASSFEDDSRVASPLDQNGSFNVVIKEEPL 330 340 350 360 370 380 >>XP_011523793 (OMIM: 147891,601719) PREDICTED: T-box tr (608 aa) initn: 822 init1: 639 opt: 820 Z-score: 545.7 bits: 110.6 E(85289): 1.2e-23 Smith-Waterman score: 832; 37.8% identity (60.8% similar) in 421 aa overlap (18-412:55-441) 10 20 30 40 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPP-ALAEGYRYPELDTPKL ::.. : . .:.:. . . : : XP_011 ARSWESKSKPGMRRPLNKMGERPEPGDAPGGPGESGKKEMLQDKGLSESEEAFRAPGPAL 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 DCFLSGMEAAPRTLAAHPPLPLLPPAMGTEPAP-----SAPEALHSLPGVSLSLENRELW .. ::. : : : :.:. :.: .: : ... .....:...::: XP_011 GE--ASAANAPEPALAAPGLS--GAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELW 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 KEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPS :.: .:::::::::::::::. .:.:::..:...:..:.:..:.: ::.. .: . XP_011 KKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVA 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB7 GKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIH ::::: .: :.:.:::::::::::::: :::...::::. ::: ::.::.::::::::.: XP_011 GKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLH 210 220 230 240 250 260 230 240 250 260 270 pF1KB7 LVRAAQ---LCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNC .:.: . . :.. .. . ::::.:::::.::: .:::::: :::::::: : . XP_011 IVKADENNAFGSKN-TAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFR--GSD- 270 280 290 300 310 280 290 300 310 320 330 pF1KB7 KRERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPA . : :: : :. ... : .:. . .: . XP_011 --DSDLRVARLQSKEYPVISKSIMRQ---------------RLISPQLSATPDVG----- 320 330 340 350 340 350 360 370 380 pF1KB7 PLCGGPSAEAYLLHPAAFHGA---PSHLPTRSPSFPEAPDSG--------RSA------P :: : .: . : . :. :. :: . :: ::. :.. : XP_011 PLLGTHQALQHYQHENGAHSQLAEPQDLPLST--FPTQRDSSLFYHCLKRRDGTRHLDLP 360 370 380 390 400 410 390 400 410 420 430 pF1KB7 YSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLPYTAPGGYLDVGSKPMY . ..:: : . : . : .:: :. ..: XP_011 CKRSYLEAPSSVGEDHYFRSPP--PYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGV 420 430 440 450 460 470 XP_011 DDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPG 480 490 500 510 520 530 >>XP_011523792 (OMIM: 147891,601719) PREDICTED: T-box tr (609 aa) initn: 822 init1: 639 opt: 820 Z-score: 545.7 bits: 110.6 E(85289): 1.2e-23 Smith-Waterman score: 834; 37.9% identity (60.4% similar) in 422 aa overlap (18-412:55-442) 10 20 30 40 pF1KB7 MYHPRELYPSLGAGYRLGPAQPGADSSFPP-ALAEGYRYPELDTPKL ::.. : . .:.:. . . : : XP_011 ARSWESKSKPGMRRPLNKMGERPEPGDAPGGPGESGKKEMLQDKGLSESEEAFRAPGPAL 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 DCFLSGMEAAPRTLAAHPPLPLLPPAMGTEPAP-----SAPEALHSLPGVSLSLENRELW .. ::. : : : :.:. :.: .: : ... .....:...::: XP_011 GE--ASAANAPEPALAAPGLS--GAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELW 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB7 KEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPS :.: .:::::::::::::::. .:.:::..:...:..:.:..:.: ::.. .: . XP_011 KKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVA 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB7 GKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIH ::::: .: :.:.:::::::::::::: :::...::::. ::: ::.::.::::::::.: XP_011 GKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLH 210 220 230 240 250 260 230 240 250 260 270 pF1KB7 LVRAAQ---LCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNC .:.: . . :.. .. . ::::.:::::.::: .:::::: :::::::: : . XP_011 IVKADENNAFGSKN-TAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFR--GSD- 270 280 290 300 310 280 290 300 310 320 330 pF1KB7 KRERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPA . : :: : :. ... : .:. . .: . XP_011 --DSDLRVARLQSKEYPVISKSIMRQ---------------RLISPQLSATPDVG----- 320 330 340 350 340 350 360 370 380 pF1KB7 PLCGGPSAEAYLLHPAAFHGA---PSHLPTRSPSFPEAPDSG-------RSA-------- :: : .: . : . :. :. :: . :: ::. : : XP_011 PLLGTHQALQHYQHENGAHSQLAEPQDLPLST--FPTQRDSSLFYHCLKRRADGTRHLDL 360 370 380 390 400 410 390 400 410 420 430 pF1KB7 PYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLPYTAPGGYLDVGSKPMY : . ..:: : . : . : .:: :. ..: XP_011 PCKRSYLEAPSSVGEDHYFRSPP--PYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSG 420 430 440 450 460 470 XP_011 VDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPP 480 490 500 510 520 530 436 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:02:48 2016 done: Sat Nov 5 01:02:49 2016 Total Scan time: 10.550 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]