Result of FASTA (omim) for
pF1KB7738
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7738, 484 aa
1>>>pF1KB7738 484 - 484 aa - 484 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7587+/-0.00034; mu= 1.8507+/- 0.021
mean_var=186.4875+/-38.549, 0's: 0 Z-trim(121.0): 155 B-trim: 0 in 0/54
Lambda= 0.093918
statistics sampled from 36846 (37008) to 36846 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.434), width: 16
Scan time: 9.660
The best scores are: opt bits E(85289)
NP_001073143 (OMIM: 600711) ETS translocation vari ( 484) 3431 477.2 4.5e-134
NP_001977 (OMIM: 600711) ETS translocation variant ( 484) 3431 477.2 4.5e-134
XP_016879838 (OMIM: 600711) PREDICTED: ETS translo ( 479) 3375 469.6 8.7e-132
NP_001248367 (OMIM: 600711) ETS translocation vari ( 445) 3173 442.2 1.4e-123
NP_001248366 (OMIM: 600711) ETS translocation vari ( 445) 3173 442.2 1.4e-123
XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1678 239.6 1.4e-62
NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 1678 239.6 1.4e-62
XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1678 239.6 1.4e-62
XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1678 239.6 1.4e-62
XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 1653 236.3 1.5e-61
XP_011513469 (OMIM: 600541) PREDICTED: ETS translo ( 491) 1653 236.3 1.5e-61
NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 1543 221.3 4.3e-57
XP_011522816 (OMIM: 600711) PREDICTED: ETS translo ( 221) 1506 216.1 7.8e-56
NP_001248368 (OMIM: 600711) ETS translocation vari ( 207) 1457 209.5 7.4e-54
NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 1442 207.6 5.4e-53
NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 1438 207.1 8.5e-53
NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 1438 207.1 8.5e-53
NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 1271 184.4 4.7e-46
NP_004445 (OMIM: 601600) ETS translocation variant ( 510) 1121 164.2 7.9e-40
NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 1084 159.1 2.3e-38
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 409 67.5 4.4e-11
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 408 67.5 7.1e-11
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 409 67.7 7.4e-11
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 409 67.7 7.7e-11
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 408 67.5 7.8e-11
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 409 67.7 7.8e-11
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 409 67.7 8.2e-11
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 408 67.5 8.3e-11
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 409 67.7 8.3e-11
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 409 67.7 8.3e-11
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 409 67.7 8.8e-11
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 405 67.2 1.2e-10
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 405 67.2 1.2e-10
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 405 67.2 1.2e-10
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 405 67.2 1.5e-10
NP_068567 (OMIM: 600246) ETS domain-containing pro ( 405) 389 64.9 4.7e-10
XP_016856069 (OMIM: 600246) PREDICTED: ETS domain- ( 413) 389 65.0 4.8e-10
NP_001244097 (OMIM: 311040) ETS domain-containing ( 95) 376 62.8 4.8e-10
XP_005245007 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 389 65.0 4.9e-10
XP_005245008 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 389 65.0 4.9e-10
NP_001964 (OMIM: 600246) ETS domain-containing pro ( 431) 389 65.0 4.9e-10
XP_016884828 (OMIM: 311040) PREDICTED: ETS domain- ( 428) 380 63.7 1.1e-09
NP_001107595 (OMIM: 311040) ETS domain-containing ( 428) 380 63.7 1.1e-09
NP_005220 (OMIM: 311040) ETS domain-containing pro ( 428) 380 63.7 1.1e-09
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 374 62.9 2e-09
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 374 62.9 2e-09
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 368 62.0 2.2e-09
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 365 61.6 3.1e-09
NP_005221 (OMIM: 600247) ETS domain-containing pro ( 407) 367 62.0 3.7e-09
XP_006719338 (OMIM: 600247) PREDICTED: ETS domain- ( 407) 367 62.0 3.7e-09
>>NP_001073143 (OMIM: 600711) ETS translocation variant (484 aa)
initn: 3431 init1: 3431 opt: 3431 Z-score: 2527.9 bits: 477.2 E(85289): 4.5e-134
Smith-Waterman score: 3431; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)
10 20 30 40 50 60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
430 440 450 460 470 480
pF1KB7 GYSY
::::
NP_001 GYSY
>>NP_001977 (OMIM: 600711) ETS translocation variant 4 i (484 aa)
initn: 3431 init1: 3431 opt: 3431 Z-score: 2527.9 bits: 477.2 E(85289): 4.5e-134
Smith-Waterman score: 3431; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)
10 20 30 40 50 60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
430 440 450 460 470 480
pF1KB7 GYSY
::::
NP_001 GYSY
>>XP_016879838 (OMIM: 600711) PREDICTED: ETS translocati (479 aa)
initn: 2106 init1: 2082 opt: 3375 Z-score: 2487.0 bits: 469.6 E(85289): 8.7e-132
Smith-Waterman score: 3375; 99.0% identity (99.0% similar) in 484 aa overlap (1-484:1-479)
10 20 30 40 50 60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPG-----YGYE
250 260 270 280 290
310 320 330 340 350 360
pF1KB7 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
420 430 440 450 460 470
pF1KB7 GYSY
::::
XP_016 GYSY
>>NP_001248367 (OMIM: 600711) ETS translocation variant (445 aa)
initn: 3173 init1: 3173 opt: 3173 Z-score: 2339.6 bits: 442.2 E(85289): 1.4e-123
Smith-Waterman score: 3173; 100.0% identity (100.0% similar) in 445 aa overlap (40-484:1-445)
10 20 30 40 50 60
pF1KB7 LDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
::::::::::::::::::::::::::::::
NP_001 MDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
10 20 30
70 80 90 100 110 120
pF1KB7 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB7 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
400 410 420 430 440
>>NP_001248366 (OMIM: 600711) ETS translocation variant (445 aa)
initn: 3173 init1: 3173 opt: 3173 Z-score: 2339.6 bits: 442.2 E(85289): 1.4e-123
Smith-Waterman score: 3173; 100.0% identity (100.0% similar) in 445 aa overlap (40-484:1-445)
10 20 30 40 50 60
pF1KB7 LDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
::::::::::::::::::::::::::::::
NP_001 MDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
10 20 30
70 80 90 100 110 120
pF1KB7 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB7 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
400 410 420 430 440
>>XP_011513470 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 1654 init1: 868 opt: 1678 Z-score: 1244.4 bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)
10 20 30 40 50 60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
:. :::::: .... : . .. :... .: :::.::::::..
XP_011 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
::::::::::::.:::::::...:.::::. .:::::.:: .. . .::.. :. . .
XP_011 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
::.:::. :::: :.... : . ...:..:. .: .: : ::
XP_011 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
: .: .: :.. : . :.:: :: : ::.:.::: :.: :.::::
XP_011 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
::::.::. . :.. .. .: ..:::: ::::::.: .: :.:.. ::: .
XP_011 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
:: .: : .:: : : ::.:::::::.:::::: : .:::: :::::.:::::::
XP_011 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
:::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
XP_011 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
:::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
XP_011 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
410 420 430 440 450 460
470 480
pF1KB7 ELAGPAQPFGPKGGYSY
: .: .: . :: :
XP_011 E-GGCCNPHPYNEGYVY
470
>>NP_004947 (OMIM: 600541) ETS translocation variant 1 i (477 aa)
initn: 1654 init1: 868 opt: 1678 Z-score: 1244.4 bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)
10 20 30 40 50 60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
:. :::::: .... : . .. :... .: :::.::::::..
NP_004 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
::::::::::::.:::::::...:.::::. .:::::.:: .. . .::.. :. . .
NP_004 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
::.:::. :::: :.... : . ...:..:. .: .: : ::
NP_004 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
: .: .: :.. : . :.:: :: : ::.:.::: :.: :.::::
NP_004 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
::::.::. . :.. .. .: ..:::: ::::::.: .: :.:.. ::: .
NP_004 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
:: .: : .:: : : ::.:::::::.:::::: : .:::: :::::.:::::::
NP_004 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
:::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
NP_004 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
:::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
NP_004 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
410 420 430 440 450 460
470 480
pF1KB7 ELAGPAQPFGPKGGYSY
: .: .: . :: :
NP_004 E-GGCCNPHPYNEGYVY
470
>>XP_005249693 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 1654 init1: 868 opt: 1678 Z-score: 1244.4 bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)
10 20 30 40 50 60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
:. :::::: .... : . .. :... .: :::.::::::..
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
::::::::::::.:::::::...:.::::. .:::::.:: .. . .::.. :. . .
XP_005 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
::.:::. :::: :.... : . ...:..:. .: .: : ::
XP_005 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
: .: .: :.. : . :.:: :: : ::.:.::: :.: :.::::
XP_005 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
::::.::. . :.. .. .: ..:::: ::::::.: .: :.:.. ::: .
XP_005 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
:: .: : .:: : : ::.:::::::.:::::: : .:::: :::::.:::::::
XP_005 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
:::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
:::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
XP_005 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
410 420 430 440 450 460
470 480
pF1KB7 ELAGPAQPFGPKGGYSY
: .: .: . :: :
XP_005 E-GGCCNPHPYNEGYVY
470
>>XP_005249692 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 1654 init1: 868 opt: 1678 Z-score: 1244.4 bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)
10 20 30 40 50 60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
:. :::::: .... : . .. :... .: :::.::::::..
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
::::::::::::.:::::::...:.::::. .:::::.:: .. . .::.. :. . .
XP_005 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
::.:::. :::: :.... : . ...:..:. .: .: : ::
XP_005 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
: .: .: :.. : . :.:: :: : ::.:.::: :.: :.::::
XP_005 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
::::.::. . :.. .. .: ..:::: ::::::.: .: :.:.. ::: .
XP_005 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
:: .: : .:: : : ::.:::::::.:::::: : .:::: :::::.:::::::
XP_005 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
:::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
:::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
XP_005 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
410 420 430 440 450 460
470 480
pF1KB7 ELAGPAQPFGPKGGYSY
: .: .: . :: :
XP_005 E-GGCCNPHPYNEGYVY
470
>>XP_011513472 (OMIM: 600541) PREDICTED: ETS translocati (472 aa)
initn: 1617 init1: 868 opt: 1653 Z-score: 1226.1 bits: 236.3 E(85289): 1.5e-61
Smith-Waterman score: 1658; 57.9% identity (76.2% similar) in 449 aa overlap (49-484:37-472)
20 30 40 50 60 70
pF1KB7 SSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFV
:::.::::::..::::::::::::.:::::
XP_011 DLDKSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFV
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB7 PDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYS-SAYDPPRQIA
::...:.::::. .:::::.:: .. . .::.. :. . .::.:::. :::: :..
XP_011 PDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVG
70 80 90 100 110 120
140 150 160 170 180
pF1KB7 IKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQPHPGHGYLGEHSSVFQQP
.. : . ...:..:. .: .: : :: : .: .: :..
XP_011 MRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHR--FRRQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 L-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGG
: . :.:: :: : ::.:.::: :.: :.::::::::.::. . :.
XP_011 LSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMV----GS
190 200 210 220 230
250 260 270 280 290 300
pF1KB7 VNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SGPSPGDGAMGYGYEKPLRP
. .. .: ..:::: ::::::.: .: :.:.. ::: . :: .: : .:: :
XP_011 AASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCM---FEKGPRQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 FPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGR
: ::.:::::::.:::::: : .:::: :::::.::::::::::::::.:.::::::::
XP_011 FYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 GMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::::::.::
XP_011 GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 ALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
::::.:::::::: ::....: ..:::::::::.::: ::.:: .: .: . :: :
XP_011 ALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPE-GGCCNPHPYNEGYVY
420 430 440 450 460 470
484 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:03:20 2016 done: Sat Nov 5 01:03:22 2016
Total Scan time: 9.660 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]